WormBase Tree Display for Gene: WBGene00004749
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WBGene00004749 | SMap | S_parent | Sequence | F57C7 | |||
---|---|---|---|---|---|---|---|
Identity (6) | |||||||
Gene_info | Biotype | SO:0001217 | |||||
Gene_class | sdn | ||||||
Allele (60) | |||||||
Strain | WBStrain00031428 | ||||||
WBStrain00000144 | |||||||
WBStrain00050774 | |||||||
RNASeq_FPKM (74) | |||||||
GO_annotation | 00047443 | ||||||
00047444 | |||||||
00047445 | |||||||
00047446 | |||||||
00047447 | |||||||
00047448 | |||||||
00047449 | |||||||
00047450 | |||||||
00047451 | |||||||
00047452 | |||||||
00047453 | |||||||
00047454 | |||||||
00047455 | |||||||
00047456 | |||||||
00047457 | |||||||
00047458 | |||||||
00047459 | |||||||
00047460 | |||||||
00113124 | |||||||
Ortholog (42) | |||||||
Structured_description | Concise_description | sdn-1 encodes a homolog of vertebrate syndecan-2, a type I transmembrane heparan sulfate proteoglycan; by homology, SDN-1 is predicted to play a role in cell-cell and cell-matrix adhesion; loss of sdn-1 activity via RNA-mediated interference (RNAi) indicates that SDN-1 is required for backward locomotion and for normal development of the egg-laying system, particularly gonadal and vulval structures; SDN-1 is expressed in a subset of neuronal cell bodies and their associated processes in the nerve ring, and also in select tail neurons. | Paper_evidence | WBPaper00011289 | |||
WBPaper00018603 | |||||||
Curator_confirmed | WBPerson1843 | ||||||
Date_last_updated | 17 Jun 2004 00:00:00 | ||||||
Automated_description | Involved in embryo development; epidermis morphogenesis; and nematode larval development. Located in cell surface. Expressed in several structures, including neuroblasts; neurons; pharynx; somatic nervous system; and vulva. Human ortholog(s) of this gene implicated in several diseases, including Hodgkin's lymphoma; cleft lip; and glucose metabolism disease (multiple). Is an ortholog of human SDC1 (syndecan 1); SDC2 (syndecan 2); and SDC4 (syndecan 4). | Paper_evidence | WBPaper00065943 | ||||
Curator_confirmed | WBPerson324 | ||||||
WBPerson37462 | |||||||
Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||
Date_last_updated | 29 Nov 2023 00:00:00 | ||||||
Disease_info | Potential_model | DOID:9296 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:10659) | ||
DOID:8567 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:10658) | ||||
DOID:4195 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:10658) | ||||
DOID:3910 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:10658) | ||||
DOID:9352 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:10659) | ||||
DOID:5844 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:10661) | ||||
DOID:674 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:10659) | ||||
Molecular_info | Corresponding_CDS | F57C7.3a | |||||
F57C7.3b | |||||||
Corresponding_CDS_history | F57C7.3:wp83 | ||||||
Corresponding_transcript | F57C7.3a.1 | ||||||
F57C7.3b.1 | |||||||
Other_sequence (22) | |||||||
Associated_feature (27) | |||||||
Experimental_info | RNAi_result | WBRNAi00109528 | Inferred_automatically | RNAi_primary | |||
WBRNAi00109334 | Inferred_automatically | RNAi_primary | |||||
WBRNAi00048861 | Inferred_automatically | RNAi_primary | |||||
WBRNAi00102205 | Inferred_automatically | RNAi_primary | |||||
WBRNAi00109237 | Inferred_automatically | RNAi_primary | |||||
WBRNAi00065732 | Inferred_automatically | RNAi_primary | |||||
WBRNAi00033032 | Inferred_automatically | RNAi_primary | |||||
WBRNAi00109625 | Inferred_automatically | RNAi_primary | |||||
WBRNAi00109431 | Inferred_automatically | RNAi_primary | |||||
Expr_pattern (12) | |||||||
Drives_construct | WBCnstr00000700 | ||||||
WBCnstr00001405 | |||||||
WBCnstr00001406 | |||||||
WBCnstr00019775 | |||||||
WBCnstr00020032 | |||||||
WBCnstr00035413 | |||||||
Construct_product (13) | |||||||
Antibody | WBAntibody00000804 | ||||||
WBAntibody00002534 | |||||||
Microarray_results (26) | |||||||
Expression_cluster (124) | |||||||
Interaction (34) | |||||||
Anatomy_function | WBbtf0790 | ||||||
WBbtf0791 | |||||||
WBbtf0792 | |||||||
Map_info | Map | X | Position | 2.31221 | Error | 0.009839 | |
Positive | Positive_clone | F57C7 | Inferred_automatically | From CDS info | |||
From sequence, transcript, pseudogene data | |||||||
Mapping_data | Multi_point | 4532 | |||||
4652 | |||||||
4134 | |||||||
Pseudo_map_position | |||||||
Reference (47) | |||||||
Remark | Sequence connection from [Turnbull J, Kinnunen T]. krb 13/11/01 | ||||||
Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | ||||||
Method | Gene |