WormBase Tree Display for Gene: WBGene00001898
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WBGene00001898 | SMap | S_parent | Sequence | M163 | |||
---|---|---|---|---|---|---|---|
Identity (6) | |||||||
Gene_info | Biotype | SO:0001217 | |||||
Gene_class | his | ||||||
Allele (33) | |||||||
Legacy_information | [C.elegansII] NMK. Histone type H1. Contains intron, encodes polyadenylated RNA. [Sanicola et al. 1990] | ||||||
Strain | WBStrain00031772 | ||||||
WBStrain00034782 | |||||||
WBStrain00034807 | |||||||
WBStrain00006458 | |||||||
RNASeq_FPKM (74) | |||||||
GO_annotation | 00039072 | ||||||
00039073 | |||||||
00039074 | |||||||
00039075 | |||||||
00039076 | |||||||
00039077 | |||||||
00039078 | |||||||
00039079 | |||||||
00039080 | |||||||
00039081 | |||||||
00039082 | |||||||
00039083 | |||||||
00039084 | |||||||
00039085 | |||||||
00039086 | |||||||
00039087 | |||||||
00039088 | |||||||
00039089 | |||||||
00039090 | |||||||
00039091 | |||||||
00039092 | |||||||
00039093 | |||||||
00039094 | |||||||
00039095 | |||||||
00039096 | |||||||
00039097 | |||||||
00109613 | |||||||
00109614 | |||||||
00109615 | |||||||
00109616 | |||||||
Ortholog (80) | |||||||
Paralog | WBGene00001852 | Caenorhabditis elegans | From_analysis | TreeFam | |||
Panther | |||||||
WormBase-Compara | |||||||
WBGene00001853 | Caenorhabditis elegans | From_analysis | TreeFam | ||||
Panther | |||||||
WormBase-Compara | |||||||
WBGene00001854 | Caenorhabditis elegans | From_analysis | TreeFam | ||||
Panther | |||||||
WormBase-Compara | |||||||
WBGene00001855 | Caenorhabditis elegans | From_analysis | TreeFam | ||||
Panther | |||||||
WormBase-Compara | |||||||
WBGene00001856 | Caenorhabditis elegans | From_analysis | TreeFam | ||||
Panther | |||||||
WormBase-Compara | |||||||
WBGene00001857 | Caenorhabditis elegans | From_analysis | TreeFam | ||||
Panther | |||||||
WormBase-Compara | |||||||
Structured_description | Concise_description | his-24 encodes one of eight C. elegans H1 linker histones; HIS-24, along with the histone deacetylase SIR-2.1 and the Enhancer of zeste E(Z) ortholog MES-2, plays a key role in heterochromatin regulation and thus, in regulation of fertility and embryonic development; specifically, HIS-24 and SIR-2.1 are essential for maintenance of the histone H3K27me3 mark at subtelomeric regions in the C. elegans germ line; HIS-24 interacts specifically with the H3 K27 region, either when unmodified or when in the trimethylated (me3) state; HIS-24 is ubiquitously expressed and localizes to nuclei; in addition, in germ cells, the majority of HIS-24 localizes to the cytoplasm, in a manner dependent upon SIR-2.1 and MES proteins. | Paper_evidence | WBPaper00004630 | |||
WBPaper00028983 | |||||||
WBPaper00033091 | |||||||
Curator_confirmed | WBPerson1843 | ||||||
WBPerson567 | |||||||
Date_last_updated | 17 Nov 2010 00:00:00 | ||||||
Automated_description | Enables H3K27me3 modified histone binding activity. Involved in defense response to Gram-positive bacterium and negative regulation of gene expression. Located in chromosome, telomeric region; cytoplasm; and nucleus. Expressed in several structures, including germ line and gonad. Is an ortholog of human H1-0 (H1.0 linker histone) and H1-8 (H1.8 linker histone). | Paper_evidence | WBPaper00065943 | ||||
Curator_confirmed | WBPerson324 | ||||||
WBPerson37462 | |||||||
Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||
Date_last_updated | 29 Nov 2023 00:00:00 | ||||||
Molecular_info | Corresponding_CDS | M163.3 | |||||
Corresponding_transcript | M163.3.1 | ||||||
Other_sequence (76) | |||||||
Associated_feature (15) | |||||||
Experimental_info | RNAi_result | WBRNAi00090698 | Inferred_automatically | RNAi_primary | |||
WBRNAi00017226 | Inferred_automatically | RNAi_primary | |||||
WBRNAi00089638 | Inferred_automatically | RNAi_primary | |||||
WBRNAi00027719 | Inferred_automatically | RNAi_primary | |||||
WBRNAi00089608 | Inferred_automatically | RNAi_primary | |||||
WBRNAi00050989 | Inferred_automatically | RNAi_primary | |||||
WBRNAi00076026 | Inferred_automatically | RNAi_primary | |||||
WBRNAi00076031 | Inferred_automatically | RNAi_primary | |||||
WBRNAi00064599 | Inferred_automatically | RNAi_primary | |||||
WBRNAi00076030 | Inferred_automatically | RNAi_primary | |||||
Expr_pattern (15) | |||||||
Drives_construct | WBCnstr00000408 | ||||||
WBCnstr00000430 | |||||||
WBCnstr00002522 | |||||||
WBCnstr00007280 | |||||||
WBCnstr00009451 | |||||||
WBCnstr00013533 | |||||||
WBCnstr00015453 | |||||||
WBCnstr00015912 | |||||||
WBCnstr00036616 | |||||||
Construct_product (293) | |||||||
Regulate_expr_cluster | WBPaper00041609:hpl-1_hpl-2_downregulated | ||||||
WBPaper00041609:hpl-1_hpl-2_upregulated | |||||||
Antibody (3) | |||||||
Microarray_results (26) | |||||||
Expression_cluster (392) | |||||||
Interaction (157) | |||||||
WBProcess | WBbiopr:00000008 | ||||||
WBbiopr:00000039 | |||||||
Map_info | Map | X | Position | 16.7093 | Error | 0.005353 | |
Positive | Positive_clone | LCEH1A | |||||
M163 | Inferred_automatically | From sequence, transcript, pseudogene data | |||||
Pseudo_map_position | |||||||
Reference (29) | |||||||
Remark | Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | |||||
Method | Gene |