WormBase Tree Display for Gene: WBGene00022647

WBGene00022647 SMap: S_parent: Sequence: CHROMOSOME_X
  Identity: Version: 3
    Name: CGC_name: slc-17.1 Person_evidence: WBPerson260
            WBPerson24428
      Sequence_name: ZK54.1
      Molecular_name: ZK54.1a
        ZK54.1a.1
        CE31271
        ZK54.1b
        CE39537
        ZK54.1b.1
      Other_name: C36E6.a Curator_confirmed: WBPerson1983
          Remark: Old cosmid naming mapped via unique overlapping PCR_product on CDSs
        vst-1 Person_evidence: WBPerson24428
        CELE_ZK54.1 Accession_evidence: NDB BX284606
      Public_name: slc-17.1
    DB_info: Database: AceView gene XS76
        WormQTL gene WBGene00022647
        WormFlux gene WBGene00022647
        NDB locus_tag CELE_ZK54.1
        Panther gene CAEEL|WormBase=WBGene00022647|UniProtKB=Q23514
          family PTHR11662
        NCBI gene 181777
        RefSeq protein NM_001047835.5
            NM_001047836.7
        TrEMBL UniProtAcc Q23514
            Q2PJ91
        UniProt_GCRP UniProtAcc Q23514
        OMIM gene 604322
    Species: Caenorhabditis elegans
    History: Version_change: 1 28 May 2004 13:31:06 WBPerson1971 Event: Imported: Initial conversion from CDS class of stlace from WS125
        2 27 Jun 2014 15:53:55 WBPerson2970 Name_change: CGC_name: slc-17.1
        3 26 Jan 2024 23:28:21 WBPerson51134 Name_change: CGC_name: slc-17.1
                Other_name: vst-1
    Status: Live
  Gene_info: Biotype: SO:0001217
    Gene_class: slc
    Allele (52)
    RNASeq_FPKM (74)
    GO_annotation: 00078712
      00078713
      00078714
      00078715
      00078716
      00126688
      00126689
    Ortholog (34)
    Paralog (58)
    Structured_description: Automated_description: Predicted to enable transmembrane transporter activity. Predicted to be involved in monoatomic anion transport. Located in sarcoplasmic reticulum. Human ortholog(s) of this gene implicated in sialuria. Is an ortholog of human SLC17A5 (solute carrier family 17 member 5). Paper_evidence: WBPaper00065943
          Curator_confirmed: WBPerson324
            WBPerson37462
          Inferred_automatically: This description was generated automatically by a script based on data from the WS291 version of WormBase
          Date_last_updated: 29 Nov 2023 00:00:00
  Disease_info: Potential_model: DOID:3659 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:10933)
  Molecular_info: Corresponding_CDS: ZK54.1a
      ZK54.1b
    Corresponding_CDS_history: ZK54.1:wp152
    Corresponding_transcript: ZK54.1a.1
      ZK54.1b.1
    Other_sequence (46)
    Associated_feature: WBsf654742
      WBsf654743
      WBsf671527
      WBsf1008930
      WBsf1008931
      WBsf1008932
  Experimental_info: RNAi_result: WBRNAi00000487 Inferred_automatically: RNAi_primary
      WBRNAi00059497 Inferred_automatically: RNAi_primary
      WBRNAi00029614 Inferred_automatically: RNAi_primary
      WBRNAi00081656 Inferred_automatically: RNAi_primary
      WBRNAi00011703 Inferred_automatically: RNAi_primary
      WBRNAi00022048 Inferred_automatically: RNAi_primary
      WBRNAi00059498 Inferred_automatically: RNAi_primary
    Expr_pattern: Expr9424
      Expr1026076
      Expr1040006
      Expr1162912
      Expr2015857
      Expr2034090
    Drives_construct: WBCnstr00024082
    Construct_product (2)
    Microarray_results (28)
    Expression_cluster: WBPaper00031040:TGF-beta_adult_upregulated
      WBPaper00032528:L3_enriched
      WBPaper00032976:non_compensated_genes
      WBPaper00037950:A-class-motor-neurons_L1-larva_expressed
      WBPaper00037950:A-class-motor-neurons_L2-larva_expressed
      WBPaper00037950:A-class-motor-neurons_larva_enriched
      WBPaper00037950:A-class-motor-neurons_larva_SelectivelyEnriched
      WBPaper00037950:all-neurons_L2-larva_expressed
      WBPaper00037950:AVA-neuron_L1-larva_expressed
      WBPaper00037950:BAG-neuron_blastula-embryo_expressed
      WBPaper00037950:BAG-neuron_embryo_enriched
      WBPaper00037950:BAG-neuron_embryo_SelectivelyEnriched
      WBPaper00037950:dopaminergic-neurons_L3-L4-larva_expressed
      WBPaper00037950:excretory-cell_L2-larva_expressed
      WBPaper00037950:GABAergic-motor-neurons_L2-larva_expressed
      WBPaper00037950:glr-1(+)-neurons_L2-larva_expressed
      WBPaper00037950:hypodermis_L3-L4-larva_expressed
      WBPaper00044736:flat_dev_expression
      WBPaper00045417:128Q-huntingtin_downreglated
      WBPaper00045420:fertilization_downregulated_transcript
      WBPaper00045521:Gender_Neutral
      WBPaper00048988:neuron_enriched
      WBPaper00048988:neuron_expressed
      WBPaper00049545:jmjd-3.1(+)_upregulated
      WBPaper00049920:Glucose-Diet_upregulated_hyl-2(tm2031)
      WBPaper00049920:Glucose-Diet_upregulated_N2
      WBPaper00050163:chd-3(eh4);let-418(RNAi)_upregulated_100-cell-embryo
      WBPaper00050344:AFD-neuron_enriched
      WBPaper00050344:PLM-neuron_enriched
      WBPaper00050488:20C_vs_25C_regulated_mir-34(gk437)_adult
      WBPaper00050488:20C_vs_25C_regulated_mir-34(OverExpression)_adult
      WBPaper00050488:20C_vs_25C_regulated_N2_adult
      WBPaper00050488:adult_vs_dauer_regulated_N2_20C
      WBPaper00050488:mir-34(gk437)_vs_mir-34(OverExpression)_regulated_dauer_20C
      WBPaper00050488:N2_vs_mir-34(gk437)_regulated_dauer_20C
      WBPaper00050859:upregulated_P-granule(-)GFP(+)_vs_control_day2-adult
      WBPaper00050859:upregulated_P-granule(-)GFP(-)_vs_control_day2-adult
      WBPaper00050990:body-muscle_expressed
      WBPaper00050990:GABAergic-neuron_expressed
      WBPaper00050990:hypodermis_expressed
      WBPaper00050990:intestine_expressed
      WBPaper00050990:NMDA-neuron_expressed
      WBPaper00051558:aging_regulated
      WBPaper00052884:emb-4(hc60)_upregulated
      WBPaper00053184:sma-4(rax3)_upregulated
      WBPaper00053302:stavudine_24h_regulated
      WBPaper00053302:zidovudine_72h_regulated
      WBPaper00053388:dauer_regulated_Cluster4
      WBPaper00054758:alg-1(gk204)_upregulated
      WBPaper00055354:Psora-Allantoin_downregulated
      WBPaper00055354:Rapamycin-Allantoin_downregulated
      WBPaper00055565:AVK_enriched
      WBPaper00055648:male-CEM-neurons_expressed
      WBPaper00055648:male-tail_expressed
      WBPaper00056090:E.faecalis_upregulated_hpx-2(dg047)
      WBPaper00056443:sek-1(km4)_upregulated
      WBPaper00056471:aak-1(tm1944);aak-2(ok524)_upregulated
      WBPaper00056826:hmc_biased
      WBPaper00056997:nmad-1(ok3133)_upregulated_germline_25C
      WBPaper00057288:Cold_downregulated_transcript
      WBPaper00058598:mex-3(eu149)_upregulated
      WBPaper00058598:sin-3(tm1276)_downregulated
      WBPaper00058691:sin-3(tm1276)_downregulated
      WBPaper00058969:RIS_enriched
      WBPaper00059027:neuron-synapses_depleted
      WBPaper00059598:HeatShock_downregulated
      WBPaper00059664:srbc-48(ac23)_upregulated
      WBPaper00059763:neuron_expressed
      WBPaper00060014:set-2(tm1630)_downregulated
      WBPaper00060459:bcat-1(RNAi)_upregulated
      WBPaper00060661:sensory-neuron_enriched
      WBPaper00060811:L1_vs_adult_upregulated_neural
      WBPaper00060909:atfs-1(cmh15)_downregulated
      WBPaper00061203:let-418(n3536)_upregulated
      WBPaper00061203:sin-3(tm1276)_upregulated
      WBPaper00061203:spr-1(ok2144)_upregulated
      WBPaper00061340:AIA
      WBPaper00061340:AIB
      WBPaper00061340:AIM
      WBPaper00061340:AIN
      WBPaper00061340:AIY
      WBPaper00061340:AIZ
      WBPaper00061340:ALA
      WBPaper00061340:AVE
      WBPaper00061340:AVG
      WBPaper00061340:AVJ
      WBPaper00061340:AVK
      WBPaper00061340:AVL
      WBPaper00061340:BAG
      WBPaper00061340:CAN
      WBPaper00061340:DVA
      WBPaper00061340:DVC
      WBPaper00061340:IL1
      WBPaper00061340:Rectal_cell
      WBPaper00061340:RIA
      WBPaper00061340:RIB
      WBPaper00061340:RID
      WBPaper00061340:RIM
      WBPaper00061340:RIS
      WBPaper00061340:RIV
      WBPaper00061340:RME
      WBPaper00061340:SMB
      WBPaper00061340:SMD
      WBPaper00061439:unc-30(ok613)_upregulated
      WBPaper00061439:unc-30(ok613)_upregulated_P.aeruginosa-infection
      WBPaper00061466:nath-10(icb99)_downregulated
      WBPaper00061527:F54D5.3_7003-F54D5.3_7004
      WBPaper00061527:rgs-2_11061-pde-1
      WBPaper00061651:ALA_enriched
      WBPaper00061651:DVB_enriched
      WBPaper00061651:HSN_enriched
      WBPaper00061651:PDA_enriched
      WBPaper00061651:PVR_enriched
      WBPaper00061651:RMG_enriched
      WBPaper00061902:camt-1(ok515)_regulated_RMG
      WBPaper00062103:neuron_enriched
      WBPaper00062159:hda-2(ok1479)_upregulated
      WBPaper00062325:muscle_depleted_coding-RNA
      WBPaper00062590:Aging_downregulated_hypodermis
      WBPaper00064088:Day-1-adult_vs_L4_downregulated_fem-3(q20)
      WBPaper00064088:Day-3-adult_vs_L4_downregulated_fem-3(q20)
      WBPaper00064315:mes-3(bn199)_upregulated_PGCs
      WBPaper00064315:mes-4(bn73)_upregulated_EGCs
      WBPaper00064315:mes-4(bn73)_upregulated_PGCs
      WBPaper00065096:25C_vs_20C_downregulated
      WBPaper00065581:hpk-1(pk1393)_upregulated
      WBPaper00065749:Heat-Shock_downregulated_endu-2(tm4977)
      WBPaper00065835:Day5_vs_Day1_downregulated
      WBPaper00065841:17_0
      WBPaper00065993:glp-1(e2141)_upregulated
      WBPaper00066146:germline-inx-14(RNAi)_upregulated_PA14
      cgc4489_group_19
      cgc4489_group_20
      WBPaper00005124:cholesterol_10-9M_regulated
      WBPaper00024671:AFD_AWB_vs_unsorted_upregulated
      WBPaper00025032:cluster_2
      WBPaper00025141:N2_Expressed_Genes
      WBPaper00025141:unc-4::GFP_Expressed_Genes
      WBPaper00026929:sir-2.1_overexpression_regulated
      WBPaper00026980:intestine_enriched
      WBPaper00030839:Larval_Pan_Neuronal
      WBPaper00031003:0hr_muscle_depleted
      WBPaper00031003:24hr_muscle_depleted
      WBPaper00031003:total_muscle_depleted
      WBPaper00031532:Larva_Pan_Neuronal_Enriched
      WBPaper00031832:slr-2_regulated
      WBPaper00032165:A_to_C_transit_increased
      WBPaper00035588:alg-1(-)_upregulated
      WBPaper00036286:Pattern_C
      WBPaper00037695:LD_3-day
      WBPaper00040184:hcf-1nc_sir-2.1nc_daf-2up
      WBPaper00040985:AIN-2_L4_intestine
      WBPaper00041002:HQ_3d_2.0mM_Up
      WBPaper00041174:environmental
      WBPaper00041174:genotypic
      WBPaper00041174:genotypic_and_environmental
      WBPaper00041939:control_vs_EtBr-exposed_48h
      WBPaper00041939:control_vs_UVC-EtBr-exposed_48h
      WBPaper00045263:isp-1(qm150)_upregulated
      WBPaper00045263:nuo-6(qm200)_upregulated
      WBPaper00048989:eat-2(ad465)_rapamycin_downregulated
      WBPaper00048989:N2_rapamycin_upregulated
      WBPaper00053236:Starvation_regulated_GR1307
      WBPaper00053236:Starvation_regulated_N2
      WBPaper00057098:SiO2-nanoparticles_upregulated
      [cgc6390]:Cluster_C
      [cgc6390]:male_sex-enriched
    Interaction (13)
  Map_info: Map: X Position: 24.142
    Positive: Positive_clone: ZK54 Inferred_automatically: From sequence, transcript, pseudogene data
    Pseudo_map_position
  Reference: WBPaper00038444
    WBPaper00038491
    WBPaper00055090
  Remark: Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. CGC_data_submission
    [200225 pad] Modified Map position as it was a reverse physical that could not be fixed by automated methods. (24.1162)
  Method: Gene