WormBase Tree Display for Gene: WBGene00020275

WBGene00020275 SMap: S_parent: Sequence: T05H4
  Identity: Version: 2
    Name: CGC_name: atp-4 Person_evidence: WBPerson1157
      Sequence_name: T05H4.12
      Molecular_name: T05H4.12
        T05H4.12.1
        CE13291
        T05H4.12.2
      Other_name: CELE_T05H4.12 Accession_evidence: NDB BX284605
      Public_name: atp-4
    DB_info: Database: AceView gene 5G906
        WormQTL gene WBGene00020275
        WormFlux gene WBGene00020275
        NDB locus_tag CELE_T05H4.12
        Panther gene CAEEL|WormBase=WBGene00020275|UniProtKB=O16517
          family PTHR12441
        NCBI gene 179025
        RefSeq protein NM_001392530.1
        TrEMBL UniProtAcc O16517
        UniProt_GCRP UniProtAcc O16517
    Species: Caenorhabditis elegans
    History: Version_change: 1 28 May 2004 13:31:02 WBPerson1971 Event: Imported: Initial conversion from CDS class of stlace from WS125
        2 31 Aug 2005 14:07:05 WBPerson2970 Name_change: CGC_name: atp-4
    Status: Live
  Gene_info: Biotype: SO:0001217
    Gene_class: atp
    Allele (36)
    Strain: WBStrain00037564
    RNASeq_FPKM (74)
    GO_annotation (12)
    Contained_in_operon: CEOP5108
    Ortholog (31)
    Structured_description: Automated_description: Predicted to enable proton transmembrane transporter activity. Predicted to be involved in proton motive force-driven ATP synthesis and proton transmembrane transport. Predicted to be located in mitochondrial inner membrane. Predicted to be part of mitochondrial proton-transporting ATP synthase complex. Human ortholog(s) of this gene implicated in essential hypertension. Is an ortholog of human ATP5PF (ATP synthase peripheral stalk subunit F6). Paper_evidence: WBPaper00065943
          Curator_confirmed: WBPerson324
            WBPerson37462
          Inferred_automatically: This description was generated automatically by a script based on data from the WS291 version of WormBase
          Date_last_updated: 29 Nov 2023 00:00:00
  Disease_info: Potential_model: DOID:10825 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:847)
  Molecular_info: Corresponding_CDS: T05H4.12
    Corresponding_transcript: T05H4.12.1
      T05H4.12.2
    Other_sequence (54)
    Associated_feature: WBsf652701
      WBsf652702
      WBsf233795
      WBsf233796
      WBsf233797
  Experimental_info: RNAi_result (35)
    Expr_pattern: Expr1025885
      Expr1038829
      Expr1156199
      Expr2009512
      Expr2027749
    Drives_construct: WBCnstr00025246
    Construct_product: WBCnstr00025246
    Microarray_results (21)
    Expression_cluster: WBPaper00032528:L3_enriched
      WBPaper00035073:mitochondria_protein
      WBPaper00036375:enriched_in_PVD_OLL
      WBPaper00038061:aldicarb_upregulated
      WBPaper00038118:aak-2(gt33)_downregulated
      WBPaper00038118:stress_downregulated_N2
      WBPaper00038289:oocyte_protein
      WBPaper00040965:lipid-droplet_associated_protein
      WBPaper00044426:rotenone_24h_upregulated
      WBPaper00044501:gld-1_let-7_regulated
      WBPaper00044616:alg-3-4_upregulated_gene
      WBPaper00044736:flat_dev_expression
      WBPaper00044746:aging_downregulated_Day5
      WBPaper00044746:aging_downregulated_HeatShock
      WBPaper00045974:NSM_enriched_totalRNA_RNAseq
      WBPaper00046012:tdp-1(ok803)_downregulated
      WBPaper00046217:gas-1(fc21)_upregulated
      WBPaper00046217:mev-1(kn1)_upregulated
      WBPaper00046446:rapid-synthesized_AgingAdult
      WBPaper00048988:neuron_expressed
      WBPaper00049290:rsks-1(sv31)_downregulated
      WBPaper00049545:jmjd-3.1(+)_downregulated
      WBPaper00049942:HeatShock_downregulated_hsf-1(RNAi)
      WBPaper00050344:PLM-neuron_enriched
      WBPaper00050488:adult_vs_dauer_regulated_N2_20C
      WBPaper00050726:OsmoticStress_regulated_Food
      WBPaper00050726:OsmoticStress_regulated_NoFood
      WBPaper00050990:arcade_intestinal-valve_expressed
      WBPaper00050990:body-muscle_expressed
      WBPaper00050990:GABAergic-neuron_expressed
      WBPaper00050990:hypodermis_expressed
      WBPaper00050990:intestine_expressed
      WBPaper00050990:NMDA-neuron_expressed
      WBPaper00050990:pharynx_expressed
      WBPaper00050990:seam_expressed
      WBPaper00051039:germline_enriched
      WBPaper00052884:emb-4(hc60)_upregulated
      WBPaper00053184:sma-2(rax5)_downregulated
      WBPaper00053184:sma-4(rax3)_downregulated
      WBPaper00053302:stavudine_24h_regulated
      WBPaper00053302:zidovudine_24h_regulated
      WBPaper00053321:PGCs_enriched_NuGen
      WBPaper00053388:dauer_regulated_Cluster6
      WBPaper00053615:SMO-1_target
      WBPaper00053810:nuo-6(qm200)_upregulated
      WBPaper00055354:Rifampicin-Allantoin_upregulated
      WBPaper00055626:pry-1(mu38)_upregulated
      WBPaper00055827:pfd-6(gk493446)_downregulated
      WBPaper00056161:male_enriched_siRNA
      WBPaper00056284:ints-5(RNAi)_downregulated
      WBPaper00056471:S.aureus-4h_downregulated_N2
      WBPaper00056501:P.aeruginosa_downregulated_mitochondria-protein
      WBPaper00056809:smn-1(ok355)_downregulated
      WBPaper00056900:TOFU-6_interacting
      WBPaper00058598:sin-3(tm1276)_upregulated
      WBPaper00058958:100mGy-irradiation-72h_upregulated
      WBPaper00059328:mrps-5(RNAi)_upregulated_mRNA
      WBPaper00060811:L1_vs_adult_downregulated_neural
      WBPaper00061203:sin-3(tm1276)_downregulated
      WBPaper00061341:28C_24h_downregulated
      WBPaper00061341:28C_48h_downregulated
      WBPaper00061377:MYRF-1_interacting
      WBPaper00061377:MYRF-2_interacting
      WBPaper00061377:PAN-1_interacting
      WBPaper00061439:unc-30(ok613)_upregulated
      WBPaper00061439:unc-30(ok613)_upregulated_P.aeruginosa-infection
      WBPaper00061466:nath-10(icb102)_upregulated
      WBPaper00061527:F45H10.2-R53.4_21676
      WBPaper00062056:lin-37(n758)_downregulated
      WBPaper00062193:skn-1(RNAi)_upregulated
      WBPaper00062325:muscle_enriched_coding-RNA
      WBPaper00062498:PPM-1.D_interacting
      WBPaper00062554:MAGU-2_interacting
      WBPaper00064055:trl-1(cas1077)_downregulated_non-starved
      WBPaper00064055:trl-1(cas1077)_downregulated_starved
      WBPaper00064071:NHR-49_interacting
      WBPaper00064088:Day-3-adult_vs_L4_downregulated_glp-1(e2141)
      WBPaper00064201:SNA-3_interacting
      WBPaper00064315:mes-4(bn73)_downregulated_PGCs
      WBPaper00064315:mrg-1(qa6200)_downregulated_PGCs
      WBPaper00064716:paraquat_downregulated
      WBPaper00065120:body-muscle-transcriptome
      WBPaper00065373:Cisplatin_downregulated_WT
      WBPaper00065373:sek-1(km4)_downregulated_cisplatin
      WBPaper00065373:sek-1(km4)_downregulated_Ref
      cgc4386_cluster_1_4
      WBPaper00025141:N2_Expressed_Genes
      WBPaper00025141:unc-4::GFP_Expressed_Genes
      WBPaper00026929:sir-2.1_overexpression_regulated
      WBPaper00026980:intestine_enriched
      WBPaper00032165:differentially_expressed_with_age_medoid_7
      WBPaper00035560:ahr-1_downregulated
      WBPaper00036286:Pattern_G
      WBPaper00041606:CE_B.thuringiensis-DB27_regulated
      WBPaper00041606:CE_X.nematophila_regulated
      WBPaper00044091:Bpseudomallei_repressed_12h
      WBPaper00048637:lin-35(n745)_starvation_downregulated
      WBPaper00048989:eat-2(ad465)_rapamycin_downregulated
      [cgc5767]:expression_class_M
      [cgc5767]:expression_class_SM
    Interaction (49)
  Map_info (3)
  Reference: WBPaper00026715
    WBPaper00049531
    WBPaper00061870
    WBPaper00062370
    WBPaper00065341
  Remark: Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. CGC_data_submission
  Method: Gene