WormBase Tree Display for Gene: WBGene00017962

WBGene00017962 SMap: S_parent: Sequence: F31F4
  Identity: Version: 2
    Name: CGC_name: fbxa-72 Person_evidence: WBPerson655
      Sequence_name: F31F4.15
      Molecular_name: F31F4.15a
        F31F4.15a.1
        CE50796
        F31F4.15b
        CE50826
        F31F4.15b.1
      Other_name: CELE_F31F4.15 Accession_evidence: NDB BX284605
      Public_name: fbxa-72
    DB_info: Database: AceView gene 5B150
        WormQTL gene WBGene00017962
        WormFlux gene WBGene00017962
        NDB locus_tag CELE_F31F4.15
        Panther gene CAEEL|WormBase=WBGene00017962|UniProtKB=A0A0K3ARZ7
          family PTHR23015
        NCBI gene 185173
        RefSeq protein NM_001313164.3
            NM_001313163.5
        TrEMBL UniProtAcc A0A0K3ARZ7
            A0A0K3AVH4
        UniProt_GCRP UniProtAcc A0A0K3ARZ7
    Species: Caenorhabditis elegans
    History: Version_change (2)
    Status: Live
  Gene_info: Biotype: SO:0001217
    Gene_class: fbxa
    Allele (137)
    RNASeq_FPKM (74)
    Ortholog (44)
    Paralog (225)
    Structured_description: Automated_description: Enriched in several structures, including Z1.p; body wall muscle cell from C lineage; intestine; male distal tip cell; and somatic gonad precursor based on tiling array; RNA-seq; proteomic; single-cell RNA-seq; and microarray studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on microarray; RNA-seq; and proteomic studies. Is affected by twenty-four chemicals including Tunicamycin; sodium arsenite; and indole based on microarray; RNA-seq; and proteomic studies. Is predicted to encode a protein with the following domains: Domain of unknown function DUF38/FTH, Caenorhabditis species; FTH domain; and F-box A protein FB224. Paper_evidence: WBPaper00065943
          Curator_confirmed: WBPerson324
            WBPerson37462
          Inferred_automatically: This description was generated automatically by a script based on data from the WS291 version of WormBase
          Date_last_updated: 29 Nov 2023 00:00:00
  Molecular_info: Corresponding_CDS: F31F4.15a
      F31F4.15b
    Corresponding_CDS_history: F31F4.15:wp248
    Corresponding_transcript: F31F4.15a.1
      F31F4.15b.1
    Other_sequence: CBC06146_1
    Associated_feature: WBsf233285
  Experimental_info: RNAi_result: WBRNAi00031633 Inferred_automatically: RNAi_primary
      WBRNAi00046043 Inferred_automatically: RNAi_primary
      WBRNAi00014166 Inferred_automatically: RNAi_primary
      WBRNAi00114472 Inferred_automatically: RNAi_primary
    Expr_pattern: Expr1018864
      Expr1149936
      Expr2011572
      Expr2029810
    Drives_construct: WBCnstr00026884
    Construct_product: WBCnstr00026884
    Microarray_results (13)
    Expression_cluster: WBPaper00027339:daf-12(rh273)_downregulated
      WBPaper00032528:L3_enriched
      WBPaper00033065:cyc-1(RNAi)_downregulated
      WBPaper00035269:cde-1_regulated
      WBPaper00036231:long-telomeres_downregulated
      WBPaper00037682:sma-2_downregulated
      WBPaper00037950:dopaminergic-neurons_L3-L4-larva_expressed
      WBPaper00037950:excretory-cell_L2-larva_expressed
      WBPaper00037950:glr-1(+)-neurons_L2-larva_expressed
      WBPaper00037950:hypodermis_L3-L4-larva_expressed
      WBPaper00037950:hypodermis_larva_enriched
      WBPaper00037950:hypodermis_larva_SelectivelyEnriched
      WBPaper00037950:PVD-OLL-neurons_L3-L4-larva_expressed
      WBPaper00038118:aak-2(gt33)_upregulated
      WBPaper00038438:D.coniospora_12hr_downregulated_RNAseq
      WBPaper00038438:E.faecalis_24hr_upregulated_TilingArray
      WBPaper00038438:Harposporium_24hr_upregulated_RNAseq
      WBPaper00038438:S.marcescens_24hr_upregulated_RNAseq
      WBPaper00042215:wdr-23(tm1817)_downregulated
      WBPaper00042561:smgl-1(RNAi)_upregulated
      WBPaper00044578:reduced-humidity_downregulated_microarray
      WBPaper00044656:tatn-1(qd182)_downregulated
      WBPaper00044736:oscillating_dev_expression
      WBPaper00045390:tunicamycin_upregulated
      WBPaper00045390:ubc-9(RNAi)_upregulated
      WBPaper00045420:fertilization_downregulated_transcript
      WBPaper00045521:Spermatogenic
      WBPaper00046012:tdp-1(ok803)_upregulated
      WBPaper00046337:monosomal_N2_vs_daf-2_upregulated
      WBPaper00046497:B.thuringiensis_0.1mix_downregulated_6h
      WBPaper00046497:B.thuringiensis_0.1mix_downregulated_12h
      WBPaper00046497:B.thuringiensis_0.5mix_downregulated_6h
      WBPaper00046497:B.thuringiensis_0.5mix_downregulated_12h
      WBPaper00048690:hermaphrodite-Z1-Z4-daughter_enriched
      WBPaper00048690:hermaphrodite-Z1-Z4_enriched
      WBPaper00048690:male-Z1-Z4-daughter_enriched
      WBPaper00048690:male-Z1-Z4_enriched
      WBPaper00048988:neuron_expressed
      WBPaper00049134:hpk-1(pk1393)_downregulated
      WBPaper00049266:NaAsO2-Stress_regulated_N2
      WBPaper00049266:NaAsO2-Stress_regulated_trx-1(ok1449)
      WBPaper00049368:daf-2(e1370)_downregulated
      WBPaper00049498:npr-1(ur89)_regulated_6
      WBPaper00049545:rgef-1p-jmjd-1.2(+)_upregulated
      WBPaper00049635:dop-1(vs100)_downregulated
      WBPaper00049736:daf-2(e1370)_downregulated_15deg-then-25deg(12hr)
      WBPaper00049942:HeatShock_downregulated_hsf-1(RNAi)
      WBPaper00049942:HeatShock_upregulated_hsf-1(+)
      WBPaper00050096:P.aeruginosa_downregulated
      WBPaper00050488:20C_vs_25C_regulated_N2_adult
      WBPaper00050488:adult_vs_dauer_regulated_N2_20C
      WBPaper00050488:mir-34(gk437)_vs_mir-34(OverExpression)_regulated_dauer_20C
      WBPaper00050488:N2_vs_mir-34(OverExpression)_regulated_adult_25C
      WBPaper00050488:N2_vs_mir-34(OverExpression)_regulated_dauer_20C
      WBPaper00050561:indole_10-fold_downregulated
      WBPaper00050726:OsmoticStress_regulated_Food
      WBPaper00050726:starvation_regulated_LowSalt
      WBPaper00050859:upregulated_P-granule(-)GFP(+)_vs_control_day2-adult
      WBPaper00050859:upregulated_P-granule(-)GFP(-)_vs_control_day2-adult
      WBPaper00050990:intestine_enriched
      WBPaper00050990:intestine_expressed
      WBPaper00051245:epidermis_cytoplasm_expressed
      WBPaper00051245:epidermis_specific
      WBPaper00051404:alg-1(gk214)_downregulated
      WBPaper00051558:aging_regulated
      WBPaper00052884:emb-4(hc60)_upregulated
      WBPaper00053184:sma-2(rax5)_downregulated
      WBPaper00053184:sma-4(rax3)_downregulated
      WBPaper00053295:lin-22(icb38)_downregulated
      WBPaper00053295:lin-22(ot269)_downregulated
      WBPaper00053302:alovudine_24h_regulated
      WBPaper00053302:stavudine_24h_regulated
      WBPaper00053302:zidovudine_24h_regulated
      WBPaper00053318:Aging_downregulated_mRNA_N2
      WBPaper00053318:mir-71(n4115)_downregulated_mRNA
      WBPaper00053388:dauer_regulated_Cluster1
      WBPaper00053664:ins-11(tm1053)_downregulated
      WBPaper00053810:daf-2(e1370)_downregulated
      WBPaper00053810:nuo-6(qm200)_downregulated
      WBPaper00053814:15C_downregulated_PY79
      WBPaper00053814:25C_downregulated_OP50
      WBPaper00053814:OP50_vs_PY79_upregulated_PY79
      WBPaper00055060:flr-1(RNAi)_downregulated
      WBPaper00055354:eat-2(ad1116)_downregulated
      WBPaper00055354:Psora-Allantoin_downregulated
      WBPaper00055354:Rapamycin-Allantoin_downregulated
      WBPaper00055354:Rapamycin-Metformin_downregulated
      WBPaper00055354:Rapamycin-Rifampicin_downregulated
      WBPaper00055354:Rifampicin-Allantoin_downregulated
      WBPaper00055354:Rifampicin_downregulated
      WBPaper00055386:daf-2(e1370)_downregulated
      WBPaper00055827:daf-2(e1370)_downregulated
      WBPaper00055941:atfs-1(et15)_downregulated
      WBPaper00055941:nuo-6(qm200)_downregulated
      WBPaper00055944:C.butyricum_vs_OP50_downregulated
      WBPaper00055969:electromagnetic-field_downregulated
      WBPaper00055971:nhl-2(ok818)_20C_downregulated
      WBPaper00055971:nhl-2(ok818)_25C_downregulated
      WBPaper00056009:propionate_upregulated_vitamin-B12_downregulated
      WBPaper00056034:pals-22(jy3)_upregulated
      WBPaper00056090:E.faecalis_downregulated_hpx-2(dg047)
      WBPaper00056090:E.faecalis_downregulated_N2
      WBPaper00056139:soil-microbiota_downregulated
      WBPaper00056218:daf-16(mu86)_downregulated_Day7
      WBPaper00056275:P.aeruginosa_downregulated
      WBPaper00056443:sek-1(km4)_upregulated
      WBPaper00056471:aak-1(tm1944);aak-2(ok524)_upregulated
      WBPaper00056471:S.aureus-4h_downregulated_N2
      WBPaper00056731:human-amylin_downregulated
      WBPaper00056809:smn-1(ok355)_downregulated
      WBPaper00056826:SGP_biased
      WBPaper00057068:numr-1(RNAi)_downregulated
      WBPaper00057068:numr-1(RNAi)_downregulated_Cadmium
      WBPaper00058665:graphene-oxide_downregulated_mRNA
      WBPaper00058725:sftb-1(cer6)_downregulated
      WBPaper00058725:sftb-1(cer39)_downregulated
      WBPaper00058948:PA14_upregulated
      WBPaper00059117:B.subtilis_downregulated
      WBPaper00059253:stearic-acid_downregulated
      WBPaper00059421:daf-1(m40);daf-3(mgDf90)_upregulated
      WBPaper00059421:daf-3(mgDf90)_upregulated
      WBPaper00059824:rnp-6(dh1127)_regulated_OP50
      WBPaper00059839:S.maltophilia_regulated
      WBPaper00059895:wounding_downregulated
      WBPaper00059987:Wounding_downregulated
      WBPaper00060014:set-2(zr2012)_upregulated
      WBPaper00060084:cco-1(RNAi)_downregulated_lin-40(yth27)
      WBPaper00060084:cco-1(RNAi)_downregulated_N2
      WBPaper00060358:B.thuringiensis_pathogen_regulated_elt-2(RNAi)
      WBPaper00060358:B.thuringiensis_pathogen_regulated_N2
      WBPaper00060399:pqm-1(ok485)_downregulated_CoCl2_6hr
      WBPaper00060445:nfki-1(cer1)_downregulated_L4
      WBPaper00060683:hlh-11(overexpression)_upregulated
      WBPaper00060703:nas-38(ok3407)_downregulated
      WBPaper00060811:L1_vs_adult_downregulated_neural
      WBPaper00060909:atfs-1(cmh15)_downregulated
      WBPaper00060921:cat-2(e1112)_downregulated
      WBPaper00060921:tdc-1(n3419)_downregulated
      WBPaper00060921:tph-1(mg280)_downregulated
      WBPaper00061007:M.braciatum_downregulated
      WBPaper00061081:E.faecalis_downregulated_N2
      WBPaper00061081:E.faecalis_downregulated_skpo-1(ok1640)
      WBPaper00061340:BWM_far_posterior
      WBPaper00061341:28C_24h_downregulated
      WBPaper00061341:28C_48h_downregulated
      WBPaper00061527:gst-26-pho-1_10767
      WBPaper00061699:daf-18(ok480)_upregulated
      WBPaper00061818:ELKS-1_interacting
      WBPaper00061823:mex-3(spr9)_downregulated
      WBPaper00061952:daf-18(nr2037)_upregulated
      WBPaper00061952:daf-18(yh1)_upregulated
      WBPaper00062184:PA14_downregulated
      WBPaper00062193:daf-16(RNAi)_upregulated
      WBPaper00062193:hsf-1(RNAi)_downregulated
      WBPaper00062193:skn-1(RNAi)_downregulated
      WBPaper00062325:muscle_depleted_coding-RNA
      WBPaper00062345:bortezomib_4h_downregulated_N2
      WBPaper00062345:bortezomib_4h_downregulated_zip-1(jy13)
      WBPaper00062440:crh-1(n3315)_upregulated
      WBPaper00062446:nhr-8(hd117)_downregulated
      WBPaper00062456:doxycycline_upregulated_CB4856_protein
      WBPaper00062497:xpf-1(tm2842)_downregulated
      WBPaper00062590:Aging_downregulated_intestine
      WBPaper00062684:pathogen_downregulated_N2
      WBPaper00064088:Day-1-adult_vs_L4_downregulated_daf-16(mu86);glp-1(e2141)
      WBPaper00064088:Day-1-adult_vs_L4_downregulated_fem-3(q20)
      WBPaper00064088:Day-1-adult_vs_L4_downregulated_glp-1(e2141)
      WBPaper00064088:Day-3-adult_vs_L4_downregulated_daf-16(mu86);glp-1(e2141)
      WBPaper00064088:Day-3-adult_vs_L4_downregulated_fem-3(q20)
      WBPaper00064088:Day-3-adult_vs_L4_downregulated_glp-1(e2141)
      WBPaper00064107:lin-35(n745)_downregulated
      WBPaper00064130:Beta-Amyloid_24h_upregulated_mRNA
      WBPaper00064229:B.thuringiensis-Cry5Ba_upregulated
      WBPaper00064494:postdauer_upregulated_AWA
      WBPaper00064539:nhr-114(gk849)_downregulated
      WBPaper00064632:daf-2(e1370)_downregulated_intestine
      WBPaper00064716:paraquat_downregulated
      WBPaper00064871:hypoxia_upregulated_F1
      WBPaper00064871:PA14_downregulated_AWA
      WBPaper00065029:cadmium_downregulated
      WBPaper00065096:25C_vs_20C_downregulated
      WBPaper00065096:Day10_vs_Day1_downregulated
      WBPaper00065096:npr-8(ok1439)_downregulated_Day10_20C
      WBPaper00065096:npr-8(ok1439)_downregulated_Day10_25C
      WBPaper00065288:mdt-15(tm2182)_downregulated
      WBPaper00065331:100nM-ivermectin_upregulated
      WBPaper00065373:Cisplatin_downregulated_WT
      WBPaper00065392:Lb.delbrueckii_downregulated
      WBPaper00065392:Lb.gasseri_downregulated
      WBPaper00065392:Lb.rhamnosus_downregulated
      WBPaper00065581:hpk-1(pk1393)_upregulated
      WBPaper00065749:endu-2(tm4977)_downregulated
      WBPaper00065749:Heat-Shock-With-Recovery_downregulated_N2
      WBPaper00065835:Day5_vs_Day1_downregulated
      WBPaper00065835:Day11_vs_Day1_downregulated
      WBPaper00065841:58_0
      WBPaper00065841:146_0
      WBPaper00065975:P-body_vs_oocyte_depleted
      WBPaper00065975:P-body_vs_WholeAnimal_depleted
      WBPaper00065984:pals-17(syb3980)_downregulated
      WBPaper00065993:glp-1(e2141)_upregulated
      WBPaper00066038:mip-1(how5)_downregulated
      WBPaper00066062:xrep-4(lax137)_upregulated
      WBPaper00066118:cyclobutrifluram_downregulated
      WBPaper00066146:germline-inx-14(RNAi)_upregulated_PA14
      WBPaper00066204:CdCl2_upregulated_mRNA
      WBPaper00066232:ash-2(RNAi)_downregulated_WT
      cgc4489_group_3
      WBPaper00024393:strongly_regulated_dauer_genes
      WBPaper00025141:N2_Expressed_Genes
      WBPaper00026929:Resveratrol_regulated_daf-16
      WBPaper00026929:sir-2.1_overexpression_regulated
      WBPaper00026980:intestine_enriched
      WBPaper00028789:PA14_vs_gacA_downregulated_4hr
      WBPaper00028789:PA14_vs_OP50_downregulated_4hr
      WBPaper00028789:PA14_vs_OP50_downregulated_8hr
      WBPaper00029437:rde-4_downregulated
      WBPaper00030985:Erwinia_carotovora_downregulated
      WBPaper00030985:Photorhabdus_luminescens_downregulated
      WBPaper00031252:AIN-1_IP_enriched
      WBPaper00031832:slr-2_regulated
      WBPaper00031850:mdt-15(RNAi)_downregulated
      WBPaper00032948:FedUp
      WBPaper00033101:spr-5_regulated
      WBPaper00034739:N2lessDR1350
      WBPaper00034757:down_by_oxidative_stress
      WBPaper00035560:ahr-1_downregulated
      WBPaper00035892:KIM5_vs_OP50_Down
      WBPaper00035892:Y.pestis_regulated
      WBPaper00036123:Atrazine_regulated
      WBPaper00036130:mir-243_up_regulated
      WBPaper00036286:Pattern_C
      WBPaper00036464:S.aureus-RN6390_regulated
      WBPaper00038172:crh-1null_up_regulated
      WBPaper00038172:tax-6null_down_regulated
      WBPaper00040184:hcf-1down_sir-2.1down_daf-2down
      WBPaper00040858:eQTL_age_regulated_developing
      WBPaper00040963:Q200_down
      WBPaper00041002:HQ_3d_0.2mM_Up
      WBPaper00041002:HQ_3d_2.0mM_Down
      WBPaper00041606:CE_S.marcescens_regulated
      WBPaper00041606:CE_X.nematophila_regulated
      WBPaper00041876:daf-10(m79)_downreglated
      WBPaper00041939:control_vs_EtBr-exposed_48h
      WBPaper00041939:control_vs_UVC-EtBr-exposed_48h
      WBPaper00041939:control_vs_UVC-EtBr-exposed_51h
      WBPaper00041939:EtBr-exposed_vs_UVC-exposed_48h
      WBPaper00041939:UVC-EtBr-exposed_vs_UVC-exposed_51h
      WBPaper00042258:DA1877_downregulated_YoungAdult
      WBPaper00042258:HT115_downregulated_YoungAdult
      WBPaper00048989:eat-2(ad465)_downregulated_in-DMSO
      WBPaper00048989:eat-2(ad465)_rapamycin_upregulated
      WBPaper00050650:mBmkTX_downregulated
      WBPaper00053550:daf-19(m86)_downregulated_AdultDay2
      WBPaper00053688:E.faecalis_downregulated
      WBPaper00053688:E.faecium_downregulated
    Interaction (14)
  Map_info: Map: V Position: -19.9665
    Positive: Positive_clone: F31F4 Inferred_automatically: From sequence, transcript, pseudogene data
    Pseudo_map_position
  Reference: WBPaper00065331
  Remark: Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. CGC_data_submission
  Method: Gene