WormBase Tree Display for Gene: WBGene00017134

WBGene00017134 SMap: S_parent: Sequence: EEED8
  Identity: Version: 1
    Name: Sequence_name: EEED8.3
      Molecular_name: EEED8.3
        EEED8.3.1
        CE01887
      Other_name: CELE_EEED8.3 Accession_evidence: NDB BX284602
      Public_name: EEED8.3
    DB_info: Database (9)
    Species: Caenorhabditis elegans
    History: Version_change: 1 28 May 2004 13:30:58 WBPerson1971 Event: Imported: Initial conversion from CDS class of stlace from WS125
    Status: Live
  Gene_info: Biotype: SO:0001217
    Allele (22)
    RNASeq_FPKM (74)
    Ortholog (18)
    Paralog: WBGene00017141 Caenorhabditis elegans From_analysis: TreeFam
    Structured_description: Concise_description: EEED8.3 encodes a protein with similarity to fatty acid-binding proteins; loss of EEED8.3 activity via RNAi results in 20-30% embryonic lethality. Paper_evidence: WBPaper00005599
          Curator_confirmed: WBPerson1843
          Date_last_updated: 02 Aug 2007 00:00:00
      Automated_description: Enriched in germ line; germline precursor cell; head mesodermal cell; and pharyngeal muscle cell based on tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and dpy-10 based on microarray; RNA-seq; tiling array; and proteomic studies. Is affected by nineteen chemicals including Heme; methylmercury hydroxide; and rotenone based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domain: Calycin. Paper_evidence: WBPaper00065943
          Curator_confirmed: WBPerson324
            WBPerson37462
          Inferred_automatically: This description was generated automatically by a script based on data from the WS291 version of WormBase
          Date_last_updated: 29 Nov 2023 00:00:00
  Molecular_info: Corresponding_CDS: EEED8.3
    Corresponding_transcript: EEED8.3.1
    Other_sequence: FD515688.1
      CSC00979_1
    Associated_feature: WBsf644191
      WBsf657591
      WBsf657592
      WBsf221275
  Experimental_info: RNAi_result: WBRNAi00012703 Inferred_automatically: RNAi_primary
      WBRNAi00102651 Inferred_automatically: RNAi_primary
      WBRNAi00030510 Inferred_automatically: RNAi_primary
      WBRNAi00084052 Inferred_automatically: RNAi_primary
      WBRNAi00043699 Inferred_automatically: RNAi_primary
      WBRNAi00007544 Inferred_automatically: RNAi_primary
    Expr_pattern: Expr1017249
      Expr1037361
      Expr1147683
      Expr2002170
      Expr2020391
    Drives_construct: WBCnstr00027544
    Construct_product: WBCnstr00027544
    Microarray_results (17)
    Expression_cluster: WBPaper00031040:TGF-beta_adult_downregulated
      WBPaper00032097:CGH-1-associated-mRNA
      WBPaper00032528:L3_depleted
      WBPaper00033065:cyc-1(RNAi)_downregulated
      WBPaper00036738:4uM_Heme_upregulated
      WBPaper00036738:500uM_Heme_downregulated
      WBPaper00037950:BAG-neuron_blastula-embryo_expressed
      WBPaper00037950:CEP-sheath-cells_Day1-adult_expressed
      WBPaper00037950:coelomocytes_L1-larva_expressed
      WBPaper00037950:coelomocytes_L2-larva_expressed
      WBPaper00037950:dopaminergic-neurons_L3-L4-larva_expressed
      WBPaper00037950:excretory-cell_L2-larva_expressed
      WBPaper00037950:GABAergic-motor-neurons_L2-larva_expressed
      WBPaper00037950:germline-precursors_blastula-embryo_expressed
      WBPaper00037950:glr-1(+)-neurons_L2-larva_expressed
      WBPaper00037950:hypodermis_L1-larva_expressed
      WBPaper00037950:hypodermis_L3-L4-larva_expressed
      WBPaper00037950:intestine_L1-larva_expressed
      WBPaper00037950:pharyngeal-muscle_embryo_enriched
      WBPaper00037950:pharyngeal-muscle_L1-larva_expressed
      WBPaper00038118:aak-2(gt33)_upregulated
      WBPaper00038438:S.marcescens_24hr_upregulated_TilingArray
      WBPaper00042477:rsr-2(RNAi)_downregulated_TilingArray
      WBPaper00043945:MeHg_upregulated
      WBPaper00044426:rotenone_24h_upregulated
      WBPaper00044656:tatn-1(qd182)_downregulated
      WBPaper00044736:rising_dev_expression
      WBPaper00044760:germline_specific
      WBPaper00045420:fertilization_upregulated_protein
      WBPaper00045521:Oogenic
      WBPaper00045571:germline-ablation_downregulated
      WBPaper00045618:fbf-1_downregulated
      WBPaper00045618:puf-8_downregulated
      WBPaper00045729:gld-2(RNAi)_downregulated
      WBPaper00046337:monosomal_N2_vs_daf-2_upregulated
      WBPaper00046337:polysomal_daf-2_vs_daf-2;daf-16_upregulated
      WBPaper00046497:B.thuringiensis_0.1mix_downregulated_6h
      WBPaper00046497:B.thuringiensis_0.1mix_downregulated_12h
      WBPaper00046497:B.thuringiensis_0.5mix_downregulated_6h
      WBPaper00046497:B.thuringiensis_0.5mix_downregulated_12h
      WBPaper00048988:neuron_expressed
      WBPaper00049498:npr-1(ur89)_regulated_6
      WBPaper00049545:jmjd-3.1(+)_downregulated
      WBPaper00049920:hyl-2(tm2031)_downregulated
      WBPaper00049942:hsf-1(RNAi)_downregulated
      WBPaper00050225:flp-6(RNAi)_downregulated
      WBPaper00050234:lin-28(RNAi)_upregulated
      WBPaper00050488:adult_vs_dauer_regulated_N2_20C
      WBPaper00050488:mir-34(gk437)_vs_mir-34(OverExpression)_regulated_dauer_20C
      WBPaper00050488:N2_vs_mir-34(gk437)_regulated_dauer_20C
      WBPaper00050522:mafr-1(tm6082)_downregulated
      WBPaper00050726:starvation_regulated_LowSalt
      WBPaper00050801:DAF-12_dauer_regulome
      WBPaper00050801:DAF-16_dauer_regulome
      WBPaper00050859:downregulated_P-granule(-)GFP(+)_vs_control_day2-adult
      WBPaper00050859:downregulated_P-granule(-)GFP(-)_vs_control_day2-adult
      WBPaper00050990:hypodermis_expressed
      WBPaper00050990:NMDA-neuron_expressed
      WBPaper00050990:pharynx_expressed
      WBPaper00051039:ash-2(RNAi)_regulated_intestine
      WBPaper00051039:germline_enriched
      WBPaper00051461:pig-1(gm344)_upregulated
      WBPaper00051558:fog-2(q71)_regulated
      WBPaper00052885:hrde-1(tm1200)-emb-4(qm31)_regulated
      WBPaper00053154:human-amyloid-beta_tau_regulated
      WBPaper00053184:sma-2(rax5)_downregulated
      WBPaper00053184:sma-4(rax3)_downregulated
      WBPaper00053302:alovudine_72h_regulated
      WBPaper00053302:zidovudine_72h_regulated
      WBPaper00053308:SMG-2_associated_NMD(-)_upregulated_ClassI
      WBPaper00053321:embryo-to-L1_downregulated_nos-1(gv5)nos-2(RNAi)_SMARTseq
      WBPaper00053321:nos-1(gv5)nos-2(RNAi)_downregulated_L1_SMARTseq
      WBPaper00053321:PGCs_enriched_NuGen
      WBPaper00053599:female_vs_male_upregulated
      WBPaper00053599:mitosis_vs_meiosis_downregulated
      WBPaper00053599:oocyte_vs_mitosis_downregulated
      WBPaper00053606:N2_vs_elt-2(ca15)_upregulated
      WBPaper00053814:25C_downregulated_OP50
      WBPaper00054191:H3.3(null)_L1_upregulated
      WBPaper00054493:hpl-2(tm1489)_downregulated
      WBPaper00054758:alg-1(gk204)_downregulated
      WBPaper00055013:hmg-3(bar24)_upregulated
      WBPaper00055049:S.gordonii_downregulated
      WBPaper00055103:thoc-5(wy822)_downregulated
      WBPaper00055354:Psora-Allantoin_downregulated
      WBPaper00055354:Rapamycin-Metformin_downregulated
      WBPaper00055354:Rapamycin-Rifampicin_downregulated
      WBPaper00055354:Rifampicin_downregulated
      WBPaper00055648:germline_expressed
      WBPaper00055804:FBF-1-FBF-2-associated_oogenic-enriched
      WBPaper00055862:antimycin_damt-1(gk961032)_regulated
      WBPaper00055941:atfs-1(et15)_downregulated
      WBPaper00055971:nhl-2(ok818)_25C_upregulated
      WBPaper00056034:pals-22(jy3)_downregulated
      WBPaper00056090:E.faecalis_downregulated_hpx-2(dg047)
      WBPaper00056090:E.faecalis_downregulated_N2
      WBPaper00056161:hermaphrodite_enriched_siRNA
      WBPaper00056169:rrf-3(pk1426)_upregulated_L4
      WBPaper00056284:ints-6(t1903)_downregulated
      WBPaper00056290:hsp-6(mg585)_downregulated
      WBPaper00056471:aak-1(tm1944);aak-2(ok524)_downregulated
      WBPaper00056471:S.aureus-4h_upregulated_N2
      WBPaper00056826:hmc_biased
      WBPaper00057041:spc-1(cas971)_upregulated
      WBPaper00057041:unc-70(cas983)_upregulated
      WBPaper00057154:HeatShock_downregulated_mRNA
      WBPaper00057288:Cold_downregulated_transcript
      WBPaper00057288:iff-1(RNAi)_downregulated_transcript
      WBPaper00058598:mex-1(or286)_downregulated
      WBPaper00058598:mex-3(eu149)_downregulated
      WBPaper00058598:sin-3(tm1276)_upregulated
      WBPaper00058958:100mGy-irradiation-72h_downregulated
      WBPaper00059334:sacy-1(depletion)_regulated
      WBPaper00059567:olrn-1(ums9)_regulated
      WBPaper00059664:srbc-48(ac23)_downregulated
      WBPaper00059728:5ug_cholesterol_downregulated
      WBPaper00059728:20ug_cholesterol_downregulated
      WBPaper00059739:hira-1(gk835598)_upregulated_L4
      WBPaper00060014:set-2(tm1630)_upregulated
      WBPaper00060100:SiNP_downregulated_mRNA
      WBPaper00060358:B.thuringiensis_pathogen_regulated_elt-2(RNAi)
      WBPaper00060358:B.thuringiensis_pathogen_regulated_N2
      WBPaper00060445:ikb-1(nr2027)_upregulated_L4
      WBPaper00060445:nfki-1(cer1)_ikb-1(nr2027)_upregulated_L4
      WBPaper00060445:nfki-1(cer1)_upregulated_L4
      WBPaper00060459:bcat-1(RNAi)_downregulated
      WBPaper00060661:sensory-neuron_depleted
      WBPaper00060683:hlh-11(ko1)_downregulated
      WBPaper00060886:spr-5(by101);met-2(n4256)_downregulated
      WBPaper00060909:atfs-1(cmh15)_upregulated
      WBPaper00060909:atfs-1(et18)_upregulated
      WBPaper00061007:HB101_downregulated
      WBPaper00061007:S.aquatilis_downregulated
      WBPaper00061045:Y56A3A.22(cck200)_downregulated
      WBPaper00061081:E.faecalis_downregulated_N2
      WBPaper00061106:endu-2(tm4977)_downregulated
      WBPaper00061203:let-418(n3536)_downregulated
      WBPaper00061203:sin-3(tm1276)_downregulated
      WBPaper00061203:spr-1(ok2144)_downregulated
      WBPaper00061274:hypergravity_10xg_upregulated
      WBPaper00061274:hypergravity_15xg_upregulated
      WBPaper00061274:microgravity_upregulated
      WBPaper00061340:Germline
      WBPaper00061341:28C_48h_downregulated
      WBPaper00061439:unc-30(ok613)_downregulated_P.aeruginosa-infection
      WBPaper00061479:HDA-1_interacting_protein
      WBPaper00061527:T22D1.5-inx-14
      WBPaper00062118:neural-HSF-1_upregulated
      WBPaper00062159:hda-2(ok1479)_downregulated
      WBPaper00062325:muscle_depleted_coding-RNA
      WBPaper00062446:nhr-8(hd117)_downregulated
      WBPaper00062456:doxycycline_downregulated_CB4856_transcript
      WBPaper00062456:doxycycline_downregulated_N2_transcript
      WBPaper00062520:qui-1(db104)_downregulated
      WBPaper00062587:lsl-1(ljm1)_downregulated
      WBPaper00062587:lsl-1(tm4769)_downregulated
      WBPaper00062590:Aging_upregulated_hypodermis
      WBPaper00062590:Aging_upregulated_neuron
      WBPaper00062672:let-418(n3536)dcp-66(RNAi)_downregulated
      WBPaper00062672:let-418(n3536)_downregulated
      WBPaper00064071:NHR-49_interacting
      WBPaper00064156:lbp-3(overexpress)_downregulated
      WBPaper00064229:B.thuringiensis-Cry5Ba_downregulated
      WBPaper00064502:spe-44(fx110)_upregulated
      WBPaper00064505:tamoxifen_upregulated
      WBPaper00064532:pals-25(icb98)_upregulated
      WBPaper00064716:paraquat_upregulated
      WBPaper00064769:him-17(me24)_downregulated
      WBPaper00064933:bcf-1(ylf1)_downregulated_transcript
      WBPaper00064952:Day1_vs_L4_upregulated_20C
      WBPaper00064952:Day1_vs_L4_upregulated_25C
      WBPaper00064952:Day5_vs_L4_upregulated_20C
      WBPaper00064952:Day10_vs_L4_upregulated_20C
      WBPaper00065005:sams-4(RNAi)_downregulated
      WBPaper00065074:glna(-)_upregulated
      WBPaper00065096:25C_vs_20C_upregulated
      WBPaper00065096:Day10_vs_Day1_upregulated
      WBPaper00065096:npr-8(ok1439)_upregulated_Day1_20C
      WBPaper00065288:mdt-15(tm2182)_upregulated
      WBPaper00065373:sek-1(km4)_upregulated_cisplatin
      WBPaper00065623:18
      WBPaper00065926:pgph-2(overepxreesion)_upregulated
      WBPaper00065975:P-body_vs_oocyte_enriched
      WBPaper00065975:P-body_vs_WholeAnimal_enriched
      WBPaper00065984:pals-17(syb3980)_upregulated
      WBPaper00065993:glp-1(e2141)_downregulated
      WBPaper00066038:mip-1(how5)_downregulated
      WBPaper00066085:sin-3(syb2172)_downregulated
      WBPaper00066085:sin-3(tm1276)_downregulated
      WBPaper00066110:Doxorubicin_downregulated_diploid
      WBPaper00066110:tetraploid_vs_diploid_downregulated
      WBPaper00066146:germline-inx-14(RNAi)_downregulated_PA14
      WBPaper00066204:CdCl2_downregulated_mRNA
      cgc4489_group_9
      WBPaper00025032:cluster_3
      WBPaper00026929:sir-2.1_overexpression_regulated
      WBPaper00027758:Group_I
      WBPaper00030985:Serratia_marcesens_upregulated
      WBPaper00031060:2-deoxy-D-glucose_downregulated
      WBPaper00031703:heme_responsive_1
      WBPaper00032948:FedUp
      WBPaper00035873:dpy-9_regulated
      WBPaper00035873:dpy-10_regulated
      WBPaper00035905:FBF-1_Associated
      WBPaper00036130:mir-243_down_regulated
      WBPaper00036286:Pattern_F
      WBPaper00038060:SUMO-1_upregulated
      WBPaper00038172:tax-6null_up_regulated
      WBPaper00038427:lin-54_embryo_changed
      WBPaper00038427:lin-54_germline_changed
      WBPaper00040963:TA300_down
      WBPaper00041606:CE_B.thuringiensis-DB27_regulated
      WBPaper00041606:CE_S.marcescens_regulated
      WBPaper00041606:CE_X.nematophila_regulated
      WBPaper00041939:control_vs_UVC-EtBr-exposed_3h
      WBPaper00045263:0.1mM-paraquat_upregulated
      WBPaper00046083:ogt-1(ok1474)_OP50_upregulated
      WBPaper00046083:pmk-1(km25)_OP50_upregulated
      WBPaper00048989:eat-2(ad465)_rapamycin_upregulated
      WBPaper00048989:N2_rapamycin_downregulated
      WBPaper00051387:Triclosan_downregulated
      WBPaper00053236:Starvation_regulated_N2
      WBPaper00056330:mrps-5(RNAi)_downregulated
      [cgc5767]:cluster_3
      [cgc5767]:expression_class_M
      [cgc5767]:expression_class_SM
      [cgc6390]:Cluster_E
      [cgc6390]:oogenesis-enriched
    Interaction (181)
  Map_info: Positive: Positive_clone: EEED8 Inferred_automatically: From sequence, transcript, pseudogene data
    Interpolated_map_position: II -1.66777
  Reference: WBPaper00042257
  Method: Gene