WormBase Tree Display for Gene: WBGene00016729

WBGene00016729 SMap: S_parent: Sequence: C46H11
  Identity: Version: 1
    Name: Sequence_name: C46H11.3
      Molecular_name: C46H11.3
        C46H11.3.1
        CE08785
      Other_name: CELE_C46H11.3 Accession_evidence: NDB BX284601
      Public_name: C46H11.3
    DB_info: Database (11)
    Species: Caenorhabditis elegans
    History: Version_change: 1 28 May 2004 13:30:57 WBPerson1971 Event: Imported: Initial conversion from CDS class of stlace from WS125
    Status: Live
  Gene_info: Biotype: SO:0001217
    Allele (14)
    Strain: WBStrain00052076
    RNASeq_FPKM (74)
    GO_annotation (13)
    Ortholog (36)
    Paralog: WBGene00000205 Caenorhabditis elegans From_analysis: TreeFam
            Inparanoid_8
            Panther
            WormBase-Compara
    Structured_description: Automated_description: Predicted to enable actin filament binding activity. Predicted to be involved in Arp2/3 complex-mediated actin nucleation and cell migration. Predicted to be located in cytoplasm. Predicted to be part of Arp2/3 protein complex. Human ortholog(s) of this gene implicated in lung squamous cell carcinoma. Is an ortholog of human ARPC5 (actin related protein 2/3 complex subunit 5) and ARPC5L (actin related protein 2/3 complex subunit 5 like). Paper_evidence: WBPaper00065943
          Curator_confirmed (2)
          Inferred_automatically: This description was generated automatically by a script based on data from the WS291 version of WormBase
          Date_last_updated: 29 Nov 2023 00:00:00
  Disease_info: Potential_model: DOID:612 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:708)
      DOID:3908 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:708)
      DOID:3907 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:708)
  Molecular_info: Corresponding_CDS: C46H11.3
    Corresponding_transcript: C46H11.3.1
    Associated_feature: WBsf217615
  Experimental_info: RNAi_result: WBRNAi00094928 Inferred_automatically: RNAi_primary
      WBRNAi00022829 Inferred_automatically: RNAi_primary
      WBRNAi00042626 Inferred_automatically: RNAi_primary
      WBRNAi00003166 Inferred_automatically: RNAi_primary
      WBRNAi00029879 Inferred_automatically: RNAi_primary
    Expr_pattern: Expr1014216
      Expr1146611
      Expr2001696
      Expr2019923
    Drives_construct: WBCnstr00027849
    Construct_product: WBCnstr00027849
    Microarray_results (22)
    Expression_cluster: WBPaper00032528:L3_depleted
      WBPaper00037950:A-class-motor-neurons_L1-larva_expressed
      WBPaper00037950:all-neurons_L2-larva_expressed
      WBPaper00037950:bodywall-muscle_L1-larva_expressed
      WBPaper00037950:germline-precursors_blastula-embryo_expressed
      WBPaper00037950:glr-1(+)-neurons_L2-larva_expressed
      WBPaper00042477:rsr-2(RNAi)_upregulated_TilingArray
      WBPaper00044578:reduced-humidity_downregulated_microarray
      WBPaper00045774:clk-1_upregulated
      WBPaper00049266:NaAsO2-Stress_regulated_N2
      WBPaper00050488:adult_vs_dauer_regulated_N2_20C
      WBPaper00050488:mir-34(gk437)_vs_mir-34(OverExpression)_regulated_dauer_20C
      WBPaper00050488:N2_vs_mir-34(gk437)_regulated_dauer_20C
      WBPaper00053402:his-3(RNAi)_downregulated
      WBPaper00055386:daf-2(e1370)_upregulated
      WBPaper00056326:zip-3(gk3164)_upregulated_P.aeruginosa-infected
      WBPaper00057041:unc-70(cas983)_downregulated
      WBPaper00059117:B.subtilis_upregulated
      WBPaper00060358:B.thuringiensis_pathogen_regulated_elt-2(RNAi)
      WBPaper00060358:B.thuringiensis_pathogen_regulated_N2
      WBPaper00061340:AMso
      WBPaper00061527:ckr-1-T09B9.3
      WBPaper00062159:hda-2(ok1479)_upregulated
      WBPaper00062325:muscle_depleted_coding-RNA
      WBPaper00064509:static-magnetic-field_upregulated
      WBPaper00065841:34_0
      WBPaper00065841:34_1
      WBPaper00065841:44_1
      cgc4489_group_8
      cgc4489_group_18
      WBPaper00024393:strongly_regulated_dauer_genes
      WBPaper00026929:sir-2.1_overexpression_regulated
      WBPaper00026980:intestine_enriched
      WBPaper00036286:Pattern_I
      WBPaper00041939:control_vs_UVC-EtBr-exposed_51h
      WBPaper00045294:50uM_TBBP_downregulated
      WBPaper00045960:L1-L4-lethargus_upregulated
      WBPaper00045960:L4-lethargus_upregulated
      WBPaper00056330:mrps-5(RNAi)_upregulated
      [cgc6390]:Cluster_B
      [cgc6390]:Cluster_C
    Interaction (19)
  Map_info: Positive: Positive_clone: C46H11 Inferred_automatically: From sequence, transcript, pseudogene data
    Interpolated_map_position: I -0.423255
  Reference: WBPaper00038491
    WBPaper00055090
  Method: Gene