| WBGene00015971 | SMap | S_parent | Sequence | C18E3 |
|---|
| Identity | Version | 2 |
| | Name | CGC_name | swsn-2.2 | Person_evidence | WBPerson407 |
| | | | | | WBPerson552 |
| | | Sequence_name | C18E3.2 |
| | | Molecular_name | C18E3.2 |
| | | | C18E3.2.1 |
| | | | CE30249 |
| | | Other_name | CELE_C18E3.2 | Accession_evidence | NDB | BX284601 |
| | | Public_name | swsn-2.2 |
| | DB_info | Database (11) |
| | Species | Caenorhabditis elegans |
| | History | Version_change | 1 | 28 May 2004 13:30:56 | WBPerson1971 | Event | Imported | Initial conversion from CDS class of stlace from WS125 |
| | | | 2 | 11 Feb 2011 15:09:46 | WBPerson2970 | Name_change | CGC_name | swsn-2.2 |
| | Status | Live |
| Gene_info | Biotype | SO:0001217 |
| | Gene_class | swsn |
| | Allele (31) |
| | Strain | WBStrain00029672 |
| | | WBStrain00031318 |
| | | WBStrain00037543 |
| | RNASeq_FPKM (74) |
| | GO_annotation (16) |
| | Contained_in_operon | CEOP1946 |
| | Ortholog (44) |
| | Paralog | WBGene00044072 | Caenorhabditis elegans | From_analysis | Inparanoid_8 |
| | | | | | Panther |
| | | | | | WormBase-Compara |
| | | WBGene00044585 | Caenorhabditis elegans | From_analysis | modENCODE_Pseudogenes |
| | | WBGene00020779 | Caenorhabditis elegans | From_analysis | Panther |
| | | | | | WormBase-Compara |
| | | WBGene00010523 | Caenorhabditis elegans | From_analysis | WormBase-Compara |
| | Structured_description | Concise_description | swsn-2.2 encodes a homolog of Swp73/BAF60, a component of the SWI/SNF complex that is conserved from yeast to mammals and that is involved in chromatin remodeling; swsn-2.2 is probably required during mitosis of the T cells for asymmetric cell division. | Paper_evidence | WBPaper00004350 |
| | | | | Curator_confirmed | WBPerson1843 |
| | | | | | WBPerson567 |
| | | | | Date_last_updated | 01 Aug 2011 00:00:00 |
| | | Automated_description | Predicted to enable RNA polymerase II-specific DNA-binding transcription factor binding activity and transcription coregulator activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Located in condensed chromosome; nuclear envelope; and nucleoplasm. Expressed in several structures, including HSNL and HSNR. Used to study alcohol use disorder. Human ortholog(s) of this gene implicated in Coffin-Siris syndrome 11. Is an ortholog of human SMARCD1 (SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 1); SMARCD2 (SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 2); and SMARCD3 (SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3). | Paper_evidence | WBPaper00065943 |
| | | | | Curator_confirmed | WBPerson324 |
| | | | | | WBPerson37462 |
| | | | | Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase |
| | | | | Date_last_updated | 29 Nov 2023 00:00:00 |
| Disease_info | Experimental_model | DOID:1574 | Homo sapiens | Paper_evidence | WBPaper00046494 |
| | | | | Curator_confirmed | WBPerson324 |
| | | | | Date_last_updated | 20 May 2019 00:00:00 |
| | Potential_model | EFO:MONDO:0009506 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:11107) |
| | | DOID:0112372 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:11106) |
| Models_disease_asserted | WBDOannot00000665 |
| Molecular_info | Corresponding_CDS | C18E3.2 |
| | Corresponding_transcript | C18E3.2.1 |
| | Other_sequence (12) |
| | Associated_feature | WBsf643191 |
| | | WBsf643192 |
| | | WBsf656176 |
| | | WBsf983356 |
| | | WBsf217501 |
| Experimental_info | RNAi_result | WBRNAi00007940 | Inferred_automatically | RNAi_primary |
| | | WBRNAi00040936 | Inferred_automatically | RNAi_primary |
| | | WBRNAi00061241 | Inferred_automatically | RNAi_primary |
| | | WBRNAi00093893 | Inferred_automatically | RNAi_primary |
| | | WBRNAi00069103 | Inferred_automatically | RNAi_primary |
| | | WBRNAi00016521 | Inferred_automatically | RNAi_primary |
| | | WBRNAi00061240 | Inferred_automatically | RNAi_primary |
| | | WBRNAi00093974 | Inferred_automatically | RNAi_primary |
| | | WBRNAi00093943 | Inferred_automatically | RNAi_primary |
| | Expr_pattern | Expr16204 |
| | | Expr16205 |
| | | Expr1016633 |
| | | Expr1036825 |
| | | Expr1144983 |
| | | Expr2017157 |
| | | Expr2035293 |
| | Drives_construct | WBCnstr00017369 |
| | | WBCnstr00028413 |
| | | WBCnstr00042800 |
| | Construct_product | WBCnstr00028413 |
| | | WBCnstr00042800 |
| | Regulate_expr_cluster (3) |
| | Antibody | WBAntibody00002683 |
| | Microarray_results (24) |
| | Expression_cluster | WBPaper00031040:TGF-beta_adult_downregulated |
| | | WBPaper00033065:cyc-1(RNAi)_downregulated |
| | | WBPaper00035269:cde-1_regulated |
| | | WBPaper00044656:tatn-1(qd182)_downregulated |
| | | WBPaper00044736:flat_dev_expression |
| | | WBPaper00044760:germline_specific |
| | | WBPaper00045420:fertilization_downregulated_transcript |
| | | WBPaper00045521:Oogenic |
| | | WBPaper00045571:germline-ablation_downregulated |
| | | WBPaper00045729:gld-2(RNAi)_downregulated |
| | | WBPaper00046497:B.thuringiensis_0.5mix_downregulated_6h |
| | | WBPaper00048923:Aging_regulated |
| | | WBPaper00048988:neuron_expressed |
| | | WBPaper00049018:SWSN-2.2_interacting |
| | | WBPaper00049942:hsf-1(RNAi)_upregulated |
| | | WBPaper00050488:adult_vs_dauer_regulated_N2_20C |
| | | WBPaper00050488:N2_vs_mir-34(gk437)_regulated_dauer_20C |
| | | WBPaper00050522:mafr-1(tm6082)_downregulated |
| | | WBPaper00050726:OsmoticStress_regulated_Food |
| | | WBPaper00050859:downregulated_P-granule(-)GFP(+)_vs_control_day2-adult |
| | | WBPaper00050990:hypodermis_enriched |
| | | WBPaper00050990:hypodermis_expressed |
| | | WBPaper00051039:germline_enriched |
| | | WBPaper00051265:F4_morc-1(tm6048)_upregulated |
| | | WBPaper00051558:aging_regulated |
| | | WBPaper00052884:emb-4(hc60)_downregulated |
| | | WBPaper00053184:sma-2(rax5)_downregulated |
| | | WBPaper00053184:sma-4(rax3)_downregulated |
| | | WBPaper00053302:stavudine_24h_regulated |
| | | WBPaper00053302:zidovudine_72h_regulated |
| | | WBPaper00055354:Psora-Allantoin_upregulated |
| | | WBPaper00055354:Rapamycin-Metformin_upregulated |
| | | WBPaper00055626:pry-1(mu38)_upregulated |
| | | WBPaper00055648:germline_expressed |
| | | WBPaper00055971:nhl-2(ok818)_25C_upregulated |
| | | WBPaper00056090:E.faecalis_downregulated_hpx-2(dg047) |
| | | WBPaper00056284:ints-5(RNAi)_downregulated |
| | | WBPaper00056443:sek-1(km4)_downregulated |
| | | WBPaper00056471:aak-1(tm1944);aak-2(ok524)_downregulated |
| | | WBPaper00056826:SGP_biased |
| | | WBPaper00057288:Cold_downregulated_transcript |
| | | WBPaper00057288:iff-1(RNAi)_downregulated_transcript |
| | | WBPaper00058598:sin-3(tm1276)_upregulated |
| | | WBPaper00058691:WDR-5.1_interacting_protein |
| | | WBPaper00059605:MUT-16_interacting |
| | | WBPaper00059664:srbc-48(ac23)_downregulated |
| | | WBPaper00060459:bcat-1(RNAi)_downregulated |
| | | WBPaper00060661:sensory-neuron_depleted |
| | | WBPaper00060683:hlh-11(ko1)_downregulated |
| | | WBPaper00060909:atfs-1(cmh15)_upregulated |
| | | WBPaper00061007:HB101_downregulated |
| | | WBPaper00061007:S.aquatilis_downregulated |
| | | WBPaper00061203:sin-3(tm1276)_downregulated |
| | | WBPaper00061340:ADA_ADE_grandparent |
| | | WBPaper00061340:ADL_parent |
| | | WBPaper00061340:ASE_parent |
| | | WBPaper00061340:I2_grandparent |
| | | WBPaper00061340:M1_parent |
| | | WBPaper00061340:Neuroblast_ADF_AWB |
| | | WBPaper00061340:Neuroblast_AFD_RMD |
| | | WBPaper00061340:Neuroblast_ALA_RMED |
| | | WBPaper00061340:Neuroblast_ASG_AWA |
| | | WBPaper00061340:Neuroblast_ASJ_AUA |
| | | WBPaper00061340:Neuroblast_IL1_IL2 |
| | | WBPaper00061340:Neuroblast_PVC_LUA |
| | | WBPaper00061340:NSM_parent |
| | | WBPaper00061340:OLQ_grandparent |
| | | WBPaper00061340:Parent_of_exc_duct_pore_DB_1_3 |
| | | WBPaper00061340:PLM_ALN_grandparent |
| | | WBPaper00061340:RIC_parent |
| | | WBPaper00061340:URA_parent |
| | | WBPaper00061479:HDA-1_interacting_protein |
| | | WBPaper00061527:cyn-10_19153-K12H4.2 |
| | | WBPaper00061527:swsn-2.2_209-ets-6 |
| | | WBPaper00062143:PQN-59_interacting |
| | | WBPaper00062159:hda-2(ok1479)_downregulated |
| | | WBPaper00062325:muscle_depleted_coding-RNA |
| | | WBPaper00062456:doxycycline_downregulated_CB4856_protein |
| | | WBPaper00062456:doxycycline_downregulated_N2_protein |
| | | WBPaper00062498:PPM-1.D_interacting |
| | | WBPaper00064071:NHR-49_interacting |
| | | WBPaper00064088:Day-1-adult_vs_L4_downregulated_glp-1(e2141) |
| | | WBPaper00064229:B.thuringiensis-Cry5Ba_downregulated |
| | | WBPaper00064716:paraquat_upregulated |
| | | WBPaper00065096:25C_vs_20C_upregulated |
| | | WBPaper00065096:Day10_vs_Day1_upregulated |
| | | WBPaper00065373:sek-1(km4)_upregulated_cisplatin |
| | | WBPaper00065993:glp-1(e2141)_downregulated |
| | | WBPaper00066110:tetraploid_vs_diploid_downregulated |
| | | WBPaper00066146:germline-inx-14(RNAi)_downregulated_PA14 |
| | | cgc4489_group_2 |
| | | cgc4489_hermaphrodite_enriched_transcription_factors |
| | | WBPaper00025032:cluster_43 |
| | | WBPaper00025141:N2_Expressed_Genes |
| | | WBPaper00025141:unc-4::GFP_Expressed_Genes |
| | | WBPaper00026929:sir-2.1_overexpression_regulated |
| | | WBPaper00026980:intestine_enriched |
| | | WBPaper00031003:0hr_muscle_depleted |
| | | WBPaper00031003:24hr_muscle_depleted |
| | | WBPaper00031003:total_muscle_depleted |
| | | WBPaper00035873:dpy-10_regulated |
| | | WBPaper00035905:FBF-1_Associated |
| | | WBPaper00036286:Pattern_F |
| | | WBPaper00037611:RNP-8-associated |
| | | WBPaper00037695:LD_3-day |
| | | WBPaper00038060:SUMO-1_upregulated |
| | | WBPaper00039866:ClassComp_daf-19_upregulated |
| | | WBPaper00040210:Chlorpyrifos_24C_regulated |
| | | WBPaper00040858:eQTL_age_regulated_aging |
| | | WBPaper00040858:eQTL_regulated_old |
| | | WBPaper00040963:TA300_down |
| | | WBPaper00041606:CE_B.thuringiensis-DB27_regulated |
| | | WBPaper00041606:CE_S.marcescens_regulated |
| | | WBPaper00041606:CE_X.nematophila_regulated |
| | | WBPaper00041939:control_vs_UVC-EtBr-exposed_51h |
| | | WBPaper00041939:control_vs_UVC-exposed_3h |
| | | WBPaper00041939:control_vs_UVC-exposed_51h |
| | | WBPaper00041939:EtBr-exposed_vs_UVC-exposed_48h |
| | | WBPaper00041939:UVC-EtBr-exposed_vs_EtBr-exposed_51h |
| | | WBPaper00041939:UVC-EtBr-exposed_vs_UVC-exposed_51h |
| | | WBPaper00042258:DA1877_downregulated_GravidAdult |
| | | WBPaper00042331:a-SWCNTs_downregulated |
| | | WBPaper00048989:eat-2(ad465)_rapamycin_upregulated |
| | | WBPaper00048989:N2_rapamycin_downregulated |
| | | WBPaper00053236:Starvation_regulated_GR1307 |
| | | WBPaper00053236:Starvation_regulated_N2 |
| | | WBPaper00053550:daf-19(m86)_upregulated_3-fold-embryo |
| | | WBPaper00056330:mrps-5(RNAi)_downregulated |
| | | WBPaper00057098:SiO2-nanoparticles_upregulated |
| | | [cgc5767]:expression_class_E |
| | | [cgc5767]:expression_class_E_pi(23_min) |
| | | [cgc5767]:expression_class_M |
| | | [cgc5767]:expression_class_MD |
| | | [cgc5767]:expression_class_MD_pd(23_min) |
| | | [cgc5767]:expression_class_ME |
| | Interaction (345) |
| Map_info | Map | I | Position | -1.58056 | Error | 0.006827 |
| | Positive | Positive_clone | C18E3 | Inferred_automatically | From sequence, transcript, pseudogene data |
| | Pseudo_map_position |
| Reference | WBPaper00031554 |
| | WBPaper00038491 |
| | WBPaper00043854 |
| | WBPaper00046494 |
| | WBPaper00049018 |
| | WBPaper00055090 |
| | WBPaper00060275 |
| | WBPaper00065308 |
| Remark | Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission |
| Method | Gene |
