WormBase Tree Display for Gene: WBGene00014218

WBGene00014218 SMap: S_parent: Sequence: ZK1098
  Identity: Version: 2
    Name: CGC_name: prp-40 Person_evidence: WBPerson11752
      Sequence_name: ZK1098.1
      Molecular_name: ZK1098.1a
        ZK1098.1a.1
        CE03847
        ZK1098.1b
        CE46142
        ZK1098.1c
        CE00362
        ZK1098.1b.1
        ZK1098.1c.1
      Other_name: CELE_ZK1098.1 Accession_evidence: NDB BX284603
      Public_name: prp-40
    DB_info: Database (11)
    Species: Caenorhabditis elegans
    History: Version_change: 1 26 May 2004 16:54:55 WBPerson1971 Event: Imported: Initial conversion from CDS class of WS125
        2 11 Mar 2021 09:37:10 WBPerson1983 Name_change: CGC_name: prp-40
    Status: Live
  Gene_info: Biotype: SO:0001217
    Gene_class: prp
    Allele (36)
    Possibly_affected_by: WBVar02157269
    RNASeq_FPKM (74)
    GO_annotation: 00043377
      00043378
      00043379
      00043380
      00043381
      00043382
      00043383
      00120933
    Contained_in_operon: CEOP3596
    Ortholog (48)
    Structured_description: Concise_description: ZK1098.1 encodes a protein, with multiple WW/rsp5/WWP domains and FF domains, required for embryonic viability and for normally high rates of postembryonic growth. Paper_evidence: WBPaper00005654
          Curator_confirmed: WBPerson567
          Date_last_updated: 17 Jun 2004 00:00:00
      Automated_description: Predicted to enable RNA binding activity. Predicted to be involved in mRNA splicing, via spliceosome. Located in nucleus. Expressed in several structures, including body wall musculature; gonad; and nervous system. Is an ortholog of human PRPF40A (pre-mRNA processing factor 40 homolog A). Paper_evidence: WBPaper00065943
          Curator_confirmed: WBPerson324
            WBPerson37462
          Inferred_automatically: This description was generated automatically by a script based on data from the WS291 version of WormBase
          Date_last_updated: 29 Nov 2023 00:00:00
  Molecular_info: Corresponding_CDS: ZK1098.1a
      ZK1098.1b
      ZK1098.1c
    Corresponding_transcript: ZK1098.1a.1
      ZK1098.1b.1
      ZK1098.1c.1
    Other_sequence (55)
    Associated_feature (9)
  Experimental_info: RNAi_result (21)
    Expr_pattern: Expr9513
      Expr15830
      Expr1012317
      Expr1036371
      Expr1162531
      Expr2008705
      Expr2026939
    Drives_construct: WBCnstr00029218
    Construct_product: WBCnstr00014078
      WBCnstr00029218
    Microarray_results (23)
    Expression_cluster: WBPaper00031040:TGF-beta_adult_downregulated
      WBPaper00037950:A-class-motor-neurons_L2-larva_expressed
      WBPaper00037950:all-neurons_embryo_enriched
      WBPaper00037950:all-neurons_L2-larva_expressed
      WBPaper00037950:AVA-neuron_embryo_enriched
      WBPaper00037950:bodywall-muscle_L2-larva_expressed
      WBPaper00037950:coelomocytes_L2-larva_expressed
      WBPaper00037950:dopaminergic-neurons_embryo_enriched
      WBPaper00037950:excretory-cell_L2-larva_expressed
      WBPaper00037950:GABAergic-motor-neurons_embryo_enriched
      WBPaper00037950:GABAergic-motor-neurons_L2-larva_expressed
      WBPaper00037950:PVD-OLL-neurons_L3-L4-larva_expressed
      WBPaper00044426:rotenone_24h_upregulated
      WBPaper00044501:gld-1_let-7_regulated
      WBPaper00044656:tatn-1(qd182)_downregulated
      WBPaper00044736:flat_dev_expression
      WBPaper00045521:Gender_Neutral
      WBPaper00045571:germline-ablation_downregulated
      WBPaper00046497:B.thuringiensis_0.1mix_downregulated_12h
      WBPaper00046497:B.thuringiensis_0.5mix_downregulated_12h
      WBPaper00048988:neuron_expressed
      WBPaper00049545:cco-1(RNAi)_downregulated
      WBPaper00049920:Glucose-Diet_downregulated_hyl-2(tm2031)
      WBPaper00049920:Glucose-Diet_downregulated_N2
      WBPaper00050234:lin-28(RNAi)_upregulated
      WBPaper00050344:AFD-neuron_enriched
      WBPaper00050488:adult_vs_dauer_regulated_N2_20C
      WBPaper00050743:elli-1(sam-3)_upregulated
      WBPaper00050859:downregulated_P-granule(-)GFP(+)_vs_control_day2-adult
      WBPaper00050990:intestine_expressed
      WBPaper00050990:NMDA-neuron_expressed
      WBPaper00051039:germline_enriched
      WBPaper00051245:intestine_nucleus_expressed
      WBPaper00051245:nucleus_specific
      WBPaper00052884:emb-4(hc60)_downregulated
      WBPaper00053184:sma-4(rax3)_downregulated
      WBPaper00053302:stavudine_24h_regulated
      WBPaper00053302:zidovudine_72h_regulated
      WBPaper00053308:SMG-2_associated_NMD(-)_unaltered_ClassII
      WBPaper00054758:alg-1(gk204)_downregulated
      WBPaper00054758:alg-2(ok304)_downregulated
      WBPaper00055648:germline_expressed
      WBPaper00056090:E.faecalis_downregulated_hpx-2(dg047)
      WBPaper00056165:MINA-1_interacting_mRNA
      WBPaper00056275:P.aeruginosa_upregulated
      WBPaper00056275:P.aeruginosa_upregulated_pmk-1(km25)_dependent
      WBPaper00058598:sin-3(tm1276)_upregulated
      WBPaper00058725:sftb-1(cer6)_downregulated
      WBPaper00059334:SACY-1_interacting
      WBPaper00059356:BAZ-2_SET-6_interacting
      WBPaper00059471:EGL-43_interacting
      WBPaper00059664:srbc-48(ac23)_downregulated
      WBPaper00060358:B.thuringiensis_pathogen_regulated_N2
      WBPaper00060445:nfki-1(cer1)_upregulated_L4
      WBPaper00060683:hlh-11(ko1)_downregulated
      WBPaper00060811:L1_vs_adult_downregulated_neural
      WBPaper00061203:sin-3(tm1276)_downregulated
      WBPaper00061203:spr-1(ok2144)_downregulated
      WBPaper00061439:unc-30(ok613)_downregulated
      WBPaper00061439:unc-30(ok613)_downregulated_P.aeruginosa-infection
      WBPaper00061527:mtr-4_1623-W03F9.10_103
      WBPaper00061902:CAMT-1_interacting
      WBPaper00062159:hda-2(ok1479)_downregulated
      WBPaper00062193:hsf-1(RNAi)_downregulated
      WBPaper00062193:skn-1(RNAi)_downregulated
      WBPaper00062325:muscle_depleted_coding-RNA
      WBPaper00062498:PPM-1.D_interacting
      WBPaper00064071:NHR-49_interacting
      WBPaper00064716:paraquat_upregulated
      WBPaper00064789:Day6_vs_Day1_downregulated_neuron
      WBPaper00064939:vit-5(RNAi)_upregulated
      WBPaper00065096:Day10_vs_Day1_upregulated
      WBPaper00065158:AFD_enriched
      WBPaper00065373:sek-1(km4)_upregulated_cisplatin
      WBPaper00065975:P-body_vs_oocyte_enriched
      WBPaper00065975:P-body_vs_WholeAnimal_enriched
      WBPaper00065993:glp-1(e2141)_downregulated
      WBPaper00066110:tetraploid_vs_diploid_downregulated
      WBPaper00066146:germline-inx-14(RNAi)_downregulated_PA14
      cgc4386_cluster_6_1
      cgc4489_group_3
      WBPaper00025141:N2_Expressed_Genes
      WBPaper00025141:unc-4::GFP_Expressed_Genes
      WBPaper00026929:sir-2.1_overexpression_regulated
      WBPaper00026980:intestine_enriched
      WBPaper00037901:GLD-1_mRNA_targets
      WBPaper00040823:alg-1(gk214)_downregulated
      WBPaper00041002:HF_3d_2.0mM_Down
      WBPaper00041606:CE_S.marcescens_regulated
      WBPaper00041606:CE_X.nematophila_regulated
      WBPaper00042331:a-SWCNTs_downregulated
      [cgc5376]:let-60(G12V)-regulated_genes
      [cgc5767]:cluster_21
      [cgc5767]:expression_class_E
      [cgc5767]:expression_class_ET
      [cgc5767]:expression_class_ET_max(66_min)
      [cgc5767]:expression_class_E_pi(41_min)
      [cgc5767]:expression_class_E_pi(53_min)
      [cgc5767]:expression_class_M
      [cgc5767]:expression_class_ME
      [cgc5767]:expression_class_MET
      [cgc6390]:intrinsic
    Interaction (111)
  Map_info: Positive: Positive_clone: ZK1098 Inferred_automatically: From sequence, transcript, pseudogene data
    Interpolated_map_position: III 0.577519
  Reference: WBPaper00035598
    WBPaper00038444
    WBPaper00038491
    WBPaper00055090
    WBPaper00061804
    WBPaper00063335
    WBPaper00065227
  Method: Gene