WormBase Tree Display for Gene: WBGene00013920

WBGene00013920 SMap: S_parent: Sequence: ZC506
  Identity: Version: 2
    Name: CGC_name: pssy-1 Person_evidence: WBPerson1105
      Sequence_name: ZC506.3
      Molecular_name: ZC506.3
        ZC506.3.1
        CE01681
        ZC506.3.2
      Other_name: CELE_ZC506.3 Accession_evidence: NDB BX284606
      Public_name: pssy-1
    DB_info: Database (13)
    Species: Caenorhabditis elegans
    History: Version_change: 1 26 May 2004 16:54:55 WBPerson1971 Event: Imported: Initial conversion from CDS class of WS125
        2 02 Mar 2006 11:42:04 WBPerson2970 Name_change: CGC_name: pssy-1
    Status: Live
  Gene_info: Biotype: SO:0001217
    Gene_class: pssy
    Allele (53)
    RNASeq_FPKM (74)
    GO_annotation (15)
    Contained_in_operon: CEOPX107
    Ortholog (35)
    Paralog: WBGene00012095 Caenorhabditis elegans From_analysis: Panther
            WormBase-Compara
      WBGene00012897 Caenorhabditis elegans From_analysis: Panther
    Structured_description: Concise_description: pssy-1 encodes a phosphatidylserine (PS) synthase; by homology, PSSY-1 is predicted to function in the biosynthesis of phosphatidylserine; loss of pssy-1 function suppresses endocytic recyling defects in animals containing a mutation in tat-1, a P4-ATPase that functions to transport phosphatidylserine and in animals overexpressing NUM-1A, an isoform of the C. elegans Numb ortholog. Paper_evidence: WBPaper00040189
          Curator_confirmed: WBPerson1843
          Date_last_updated: 14 Oct 2011 00:00:00
      Automated_description: Predicted to enable L-serine-phosphatidylethanolamine phosphatidyltransferase activity. Predicted to be involved in phosphatidylserine biosynthetic process. Predicted to be located in endoplasmic reticulum membrane. Human ortholog(s) of this gene implicated in Lenz-Majewski hyperostotic dwarfism. Is an ortholog of human PTDSS1 (phosphatidylserine synthase 1). Paper_evidence: WBPaper00065943
          Curator_confirmed (2)
          Inferred_automatically: This description was generated automatically by a script based on data from the WS291 version of WormBase
          Date_last_updated: 29 Nov 2023 00:00:00
  Disease_info: Potential_model: DOID:0111507 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:9587)
  Molecular_info: Corresponding_CDS: ZC506.3
    Corresponding_transcript: ZC506.3.1
      ZC506.3.2
    Other_sequence (26)
    Associated_feature: WBsf648437
      WBsf663213
      WBsf1006580
      WBsf236223
      WBsf236224
      WBsf236225
      WBsf236226
  Experimental_info: RNAi_result: WBRNAi00058984 Inferred_automatically: RNAi_primary
      WBRNAi00087512 Inferred_automatically: RNAi_primary
      WBRNAi00001747 Inferred_automatically: RNAi_primary
      WBRNAi00038086 Inferred_automatically: RNAi_primary
    Expr_pattern: Chronogram2083
      Expr7173
      Expr1024311
      Expr1036228
      Expr1162417
      Expr2015137
      Expr2033375
    Drives_construct: WBCnstr00003699
      WBCnstr00029444
    Construct_product: WBCnstr00029444
    Microarray_results (22)
    Expression_cluster: WBPaper00029359_1280
      WBPaper00029359_1444
      WBPaper00029359_1504
      WBPaper00029359_1578
      WBPaper00029359_1604
      WBPaper00037682:sma-2_upregulated
      WBPaper00037950:CEP-sheath-cells_Day1-adult_expressed
      WBPaper00037950:coelomocytes_L2-larva_expressed
      WBPaper00037950:dopaminergic-neurons_L3-L4-larva_expressed
      WBPaper00037950:dopaminergic-neurons_larva_enriched
      WBPaper00037950:dopaminergic-neurons_larva_SelectivelyEnriched
      WBPaper00037950:excretory-cell_L2-larva_expressed
      WBPaper00037950:hypodermis_L3-L4-larva_expressed
      WBPaper00037950:intestine_L2-larva_expressed
      WBPaper00037950:PVD-OLL-neurons_L3-L4-larva_expressed
      WBPaper00044501:gld-1_let-7_regulated
      WBPaper00044736:flat_dev_expression
      WBPaper00045521:Oogenic
      WBPaper00046497:B.thuringiensis_0.1mix_downregulated_6h
      WBPaper00046497:B.thuringiensis_0.5mix_downregulated_6h
      WBPaper00046509:htz-1(ok3099)_downregulated
      WBPaper00046509:lin-35(n745)_downregulated
      WBPaper00048923:Aging_regulated
      WBPaper00048988:neuron_expressed
      WBPaper00049368:daf-2(e1370)_upregulated
      WBPaper00049545:jmjd-3.1(+)_upregulated
      WBPaper00049545:rgef-1p-jmjd-1.2(+)_upregulated
      WBPaper00049545:sur-5p-jmjd-1.2(+)_upregulated
      WBPaper00050344:AFD-neuron_enriched
      WBPaper00050370:dpy-21(e428)_L3_upregulated
      WBPaper00050488:adult_vs_dauer_regulated_N2_20C
      WBPaper00050726:OsmoticStress_regulated_NoFood
      WBPaper00050859:upregulated_P-granule(-)GFP(+)_vs_control_day2-adult
      WBPaper00050859:upregulated_P-granule(-)GFP(-)_vs_control_day2-adult
      WBPaper00050859:upregulated_pgl-1(ct131)_vs_control_day1-adult
      WBPaper00050990:intestine_enriched
      WBPaper00050990:intestine_expressed
      WBPaper00051039:intestine_enriched
      WBPaper00051245:intestine_cytoplasm_expressed
      WBPaper00052884:emb-4(hc60)_upregulated
      WBPaper00053184:sma-4(rax3)_downregulated
      WBPaper00053302:stavudine_24h_regulated
      WBPaper00053302:zidovudine_72h_regulated
      WBPaper00053321:lin-15B(RNAi)_downregulated_starved-L1_Truseq
      WBPaper00053321:nos-1(gv5)nos-2(RNAi)_upregulated_fed-L1_Truseq
      WBPaper00053321:nos-1(gv5)nos-2(RNAi)_upregulated_L1_SMARTseq
      WBPaper00053321:nos-1(gv5)nos-2(RNAi)_upregulated_starved-L1_Truseq
      WBPaper00053321:PGCs_depleted_NuGen
      WBPaper00053388:dauer_regulated_Cluster1
      WBPaper00053599:female_vs_male_upregulated
      WBPaper00053599:oocyte_vs_mitosis_downregulated
      WBPaper00055971:nhl-2(ok818)_25C_downregulated
      WBPaper00056275:P.aeruginosa_downregulated
      WBPaper00056275:P.aeruginosa_downregulated_atf-7(qd22qd130)_dependent
      WBPaper00056275:P.aeruginosa_downregulated_pmk-1(km25)_dependent
      WBPaper00056284:ints-11(RNAi)_downregulated
      WBPaper00056443:sek-1(km4)_upregulated
      WBPaper00056471:aak-1(tm1944);aak-2(ok524)_upregulated
      WBPaper00056471:S.aureus-4h_downregulated_N2
      WBPaper00058598:sin-3(tm1276)_downregulated
      WBPaper00058691:sin-3(tm1276)_downregulated
      WBPaper00059328:mrps-5(RNAi)_upregulated_mRNA
      WBPaper00059895:wounding_downregulated
      WBPaper00059987:Wounding_downregulated
      WBPaper00060683:hlh-11(overexpression)_downregulated
      WBPaper00060811:L1_vs_adult_upregulated_neural
      WBPaper00060909:atfs-1(cmh15)_downregulated
      WBPaper00061203:sin-3(tm1276)_upregulated
      WBPaper00061203:spr-1(ok2144)_upregulated
      WBPaper00061340:K_Kprime
      WBPaper00061340:URA_parent
      WBPaper00061341:28C_48h_downregulated
      WBPaper00061527:chd-7_16664-jmjd-3.1
      WBPaper00061527:F08G12.1_2283-cst-1_319
      WBPaper00064315:mes-3(bn199)_upregulated_EGCs
      WBPaper00064315:mes-3(bn199)_upregulated_PGCs
      WBPaper00064315:mes-4(bn73)_upregulated_EGCs
      WBPaper00065158:AFD_depleted
      WBPaper00065373:Cisplatin_upregulated_WT
      WBPaper00065373:sek-1(km4)_downregulated_cisplatin
      WBPaper00065373:sek-1(km4)_upregulated_Ref
      WBPaper00065841:28_0
      WBPaper00065975:P-body_vs_oocyte_enriched
      WBPaper00065975:P-body_vs_WholeAnimal_enriched
      WBPaper00025032:cluster_119
      WBPaper00025141:N2_Expressed_Genes
      WBPaper00026980:intestine_enriched
      WBPaper00031003:24hr_muscle_depleted
      WBPaper00031003:total_muscle_depleted
      WBPaper00034739:N2lessDR1350
      WBPaper00036286:Pattern_C
      WBPaper00040426:CYD-1_CDK-4_downregulated
      WBPaper00040603:tdp-1(lf)_down_vs_N2_FC_1.2
      WBPaper00040858:eQTL_age_regulated_developing
      WBPaper00041211:RPW-24_Up
      WBPaper00041606:CE_X.nematophila_regulated
      WBPaper00045263:0.1mM-paraquat_upregulated
      WBPaper00045263:nuo-6(qm200)_upregulated
      WBPaper00048989:N2_rapamycin_downregulated
      WBPaper00053236:Starvation_regulated_GR1307
      WBPaper00053236:Starvation_regulated_N2
      WBPaper00053688:E.faecalis_downregulated
      [cgc5767]:expression_class_E
      [cgc5767]:expression_class_E_pi(122_min)
      [cgc5767]:expression_class_E_pi(143_min)
      [cgc5767]:expression_class_M
      [cgc5767]:expression_class_ME
    Interaction: WBInteraction000286504
      WBInteraction000287546
      WBInteraction000308997
      WBInteraction000317134
      WBInteraction000378737
      WBInteraction000389768
  Map_info: Map: X Position: 1.73168
    Positive: Positive_clone: ZC506 Inferred_automatically: From sequence, transcript, pseudogene data
    Pseudo_map_position
  Reference: WBPaper00038491
    WBPaper00040189
    WBPaper00042257
    WBPaper00055090
    WBPaper00060347
  Remark: Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. CGC_data_submission
  Method: Gene