WormBase Tree Display for Gene: WBGene00013598

WBGene00013598 SMap: S_parent: Sequence: Y87G2A
  Identity: Version: 2
    Name: CGC_name: vps-28 Person_evidence (2)
      Sequence_name: Y87G2A.10
      Molecular_name: Y87G2A.10a
        Y87G2A.10a.1
        CE23139
        Y87G2A.10b
      Other_name: CELE_Y87G2A.10 Accession_evidence: NDB BX284601
      Public_name: vps-28
    DB_info: Database: WormQTL gene WBGene00013598
        WormFlux gene WBGene00013598
        NDB locus_tag CELE_Y87G2A.10
        Panther gene CAEEL|WormBase=WBGene00013598|UniProtKB=Q9NA26
          family PTHR12937
        NCBI gene 173229
        RefSeq protein NM_060981.6
            NR_023947.1
        SwissProt UniProtAcc Q9NA26
        TREEFAM TREEFAM_ID TF313364
        UniProt_GCRP UniProtAcc Q9NA26
        RNAcentral URSid URS00004A7C85
    Species: Caenorhabditis elegans
    History: Version_change: 1 26 May 2004 16:54:55 WBPerson1971 Event: Imported: Initial conversion from CDS class of WS125
        2 10 Sep 2007 09:52:01 WBPerson2970 Name_change: CGC_name: vps-28
    Status: Live
  Gene_info: Biotype: SO:0001217
    Gene_class: vps
    Allele (45)
    Strain: WBStrain00036866
    RNASeq_FPKM (74)
    GO_annotation: 00095730
      00095731
      00095732
      00095733
      00095734
      00095735
      00095736
      00095737
      00120418
      00120419
    Contained_in_operon: CEOP1712
      CEOP1708
    Ortholog (40)
    Structured_description: Concise_description: vps-28 encodes the C. elegans ortholog of S. cerevisiae vacuolar protein sorting protein Vps28p and human VPS28; VPS-28 is a component of the C. elegans ESCRT-1 (Endosomal Sorting Complex Required for Transport, other members include VPS-37, MVB-12, and TSG-101) that is required for cell surface receptor degradation via the multivesicular body sorting pathway and hence, downregulation of receptor activity. Paper_evidence: WBPaper00006395
            WBPaper00024497
            WBPaper00026641
            WBPaper00031035
          Curator_confirmed: WBPerson1843
          Date_last_updated: 09 Jul 2010 00:00:00
      Automated_description: Involved in receptor catabolic process. Part of ESCRT I complex. Is an ortholog of human VPS28 (VPS28 subunit of ESCRT-I). Paper_evidence: WBPaper00065943
          Curator_confirmed: WBPerson324
            WBPerson37462
          Inferred_automatically: This description was generated automatically by a script based on data from the WS291 version of WormBase
          Date_last_updated: 29 Nov 2023 00:00:00
  Molecular_info: Corresponding_CDS: Y87G2A.10a
    Corresponding_transcript: Y87G2A.10b
      Y87G2A.10a.1
    Other_sequence (39)
    Associated_feature: WBsf665070
      WBsf985901
      WBsf220521
  Experimental_info: RNAi_result (27)
    Expr_pattern: Expr1026125
      Expr1036083
      Expr1162015
      Expr2018018
      Expr2036155
    Microarray_results (25)
    Expression_cluster: WBPaper00032528:L3_enriched
      WBPaper00037950:A-class-motor-neurons_L2-larva_expressed
      WBPaper00037950:all-neurons_L2-larva_expressed
      WBPaper00037950:AVA-neuron_L1-larva_expressed
      WBPaper00037950:BAG-neuron_blastula-embryo_expressed
      WBPaper00037950:bodywall-muscle_L2-larva_expressed
      WBPaper00037950:CEP-sheath-cells_Day1-adult_expressed
      WBPaper00037950:dopaminergic-neurons_L3-L4-larva_expressed
      WBPaper00037950:dopaminergic-neurons_larva_enriched
      WBPaper00037950:excretory-cell_L2-larva_expressed
      WBPaper00037950:GABAergic-motor-neurons_L2-larva_expressed
      WBPaper00037950:germline-precursors_blastula-embryo_expressed
      WBPaper00037950:hypodermis_L3-L4-larva_expressed
      WBPaper00037950:hypodermis_larva_enriched
      WBPaper00037950:intestine_L2-larva_expressed
      WBPaper00037950:PVD-OLL-neurons_L3-L4-larva_expressed
      WBPaper00037950:PVD-OLL-neurons_larva_enriched
      WBPaper00038168:lin-15B(n744)_upregulated
      WBPaper00038289:oocyte_protein
      WBPaper00041072:UTX-1_interacting_protein
      WBPaper00044426:rotenone_24h_upregulated
      WBPaper00044736:flat_dev_expression
      WBPaper00045521:Gender_Neutral
      WBPaper00045571:germline-ablation_downregulated
      WBPaper00048988:neuron_expressed
      WBPaper00049545:cco-1(RNAi)_downregulated
      WBPaper00049545:jmjd-3.1(+)_downregulated
      WBPaper00050344:AFD-neuron_enriched
      WBPaper00050344:PLM-neuron_enriched
      WBPaper00050488:adult_vs_dauer_regulated_N2_20C
      WBPaper00050488:mir-34(gk437)_vs_mir-34(OverExpression)_regulated_adult_25C
      WBPaper00050488:N2_vs_mir-34(OverExpression)_regulated_adult_25C
      WBPaper00050726:OsmoticStress_regulated_Food
      WBPaper00050990:intestine_expressed
      WBPaper00050990:NMDA-neuron_expressed
      WBPaper00051039:germline_enriched
      WBPaper00053184:sma-4(rax3)_downregulated
      WBPaper00053289:DREAM-target
      WBPaper00053295:lin-22(ot269)_downregulated
      WBPaper00055354:Rifampicin-Allantoin_upregulated
      WBPaper00055648:germline_expressed
      WBPaper00056090:E.faecalis_downregulated_hpx-2(dg047)
      WBPaper00056090:E.faecalis_downregulated_N2
      WBPaper00057288:iff-1(RNAi)_upregulated_transcript
      WBPaper00058598:sin-3(tm1276)_upregulated
      WBPaper00059356:BAZ-2_SET-6_interacting
      WBPaper00060014:set-2(tm1630)_upregulated
      WBPaper00060661:sensory-neuron_enriched
      WBPaper00061203:sin-3(tm1276)_downregulated
      WBPaper00061377:MYRF-1_interacting
      WBPaper00061527:F31C3.4_6048-cutc-1_15804
      WBPaper00062159:hda-2(ok1479)_downregulated
      WBPaper00062325:muscle_depleted_coding-RNA
      WBPaper00062669:extracellular-vesicle_protein
      WBPaper00064071:NHR-49_interacting
      WBPaper00064229:B.thuringiensis-Cry5Ba_downregulated
      WBPaper00064716:paraquat_upregulated
      WBPaper00065373:Cisplatin_upregulated_WT
      WBPaper00066038:mip-1(how5)_downregulated
      WBPaper00066062:xrep-4(lax137)_upregulated
      cgc4489_group_15
      WBPaper00024671:AFD_AWB_vs_unsorted_downregulated
      WBPaper00025141:N2_Expressed_Genes
      WBPaper00025141:unc-4::GFP_Expressed_Genes
      WBPaper00026929:sir-2.1_overexpression_regulated
      WBPaper00032165:differentially_expressed_with_age_medoid_5
      WBPaper00035560:ahr-1_upregulated
      WBPaper00035905:FBF-1_Associated
      WBPaper00036123:Cadmium_regulated
      WBPaper00036286:Pattern_F
      WBPaper00038231:Cry5B_1.5-fold_upregulated
      WBPaper00038231:Cry5B_2-fold_upregulated
      WBPaper00040858:eQTL_age_regulated_aging
      WBPaper00040858:eQTL_age_regulated_developing
      WBPaper00040858:eQTL_regulated_aging
      WBPaper00041370:spg-7(RNAi)_upregulated
      WBPaper00041606:CE_B.thuringiensis-DB27_regulated
      WBPaper00041606:CE_X.nematophila_regulated
      WBPaper00045263:0.1mM-paraquat_upregulated
      [cgc5767]:expression_class_M
      [cgc5767]:expression_class_SM
    Interaction (31)
  Map_info: Map: I Position: 21.5544 Error: 0.01141
    Positive: Positive_clone: Y87G2A Inferred_automatically: From sequence, transcript, pseudogene data
    Pseudo_map_position
  Reference (13)
  Remark: Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. CGC_data_submission
  Method: Gene