WormBase Tree Display for Gene: WBGene00013168

WBGene00013168 SMap: S_parent: Sequence: Y53F4B
  Identity: Version: 2
    Name: CGC_name: arp-1 Person_evidence: WBPerson1562
      Sequence_name: Y53F4B.22
      Molecular_name: Y53F4B.22a
        Y53F4B.22a.1
        CE35675
        Y53F4B.22b
        CE48840
        Y53F4B.22b.1
      Other_name: CELE_Y53F4B.22 Accession_evidence: NDB BX284602
      Public_name: arp-1
    DB_info: Database: AceView gene 2P407
        WormQTL gene WBGene00013168
        SignaLink protein WBGene00013168
        WormFlux gene WBGene00013168
        NDB locus_tag CELE_Y53F4B.22
        Panther gene CAEEL|WormBase=WBGene00013168|UniProtKB=Q9NA98
          family PTHR11937
        NCBI gene 175162
        RefSeq protein NM_064707.7
            NM_001306622.3
        TrEMBL UniProtAcc Q9NA98
            U4PR70
        UniProt_GCRP UniProtAcc Q9NA98
    Species: Caenorhabditis elegans
    History: Version_change: 1 26 May 2004 16:54:54 WBPerson1971 Event: Imported: Initial conversion from CDS class of WS125
        2 14 Nov 2008 16:27:48 WBPerson2970 Event: Acquires_merge: WBGene00000194
      Acquires_merge: WBGene00000194
    Status: Live
  Gene_info: Biotype: SO:0001217
    Gene_class: arp
    Allele (56)
    Legacy_information: [C.elegansII] NMK. Sequence predicts protein with 50% homology to actin, 67% to vertebrate actin related protein. Antibody staining suggests located at cell division remnant. [RW]
    Strain: WBStrain00040378
    RNASeq_FPKM (74)
    GO_annotation: 00095869
    Ortholog (36)
    Paralog (11)
    Structured_description: Automated_description: Part of dynactin complex. Human ortholog(s) of this gene implicated in Down syndrome and colon cancer. Is an ortholog of human ACTR1A (actin related protein 1A). Paper_evidence: WBPaper00065943
          Curator_confirmed: WBPerson324
            WBPerson37462
          Inferred_automatically: This description was generated automatically by a script based on data from the WS291 version of WormBase
          Date_last_updated: 29 Nov 2023 00:00:00
  Disease_info: Potential_model: DOID:219 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:167)
      DOID:14250 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:167)
  Molecular_info: Corresponding_CDS (2)
    Corresponding_CDS_history: Y53F4B.22:wp109
    Corresponding_transcript: Y53F4B.22a.1
      Y53F4B.22b.1
    Other_sequence (63)
    Associated_feature: WBsf644884
      WBsf990898
      WBsf990899
      WBsf990900
      WBsf1013947
      WBsf222537
  Experimental_info: RNAi_result (17)
    Expr_pattern: Expr8526
      Expr1023806
      Expr1035850
      Expr1160714
      Expr2009406
      Expr2027642
    Construct_product: WBCnstr00001390
    Microarray_results (19)
    Expression_cluster: WBPaper00033065:cyc-1(RNAi)_downregulated
      WBPaper00037950:A-class-motor-neurons_L1-larva_expressed
      WBPaper00037950:A-class-motor-neurons_L2-larva_expressed
      WBPaper00037950:all-neurons_L2-larva_expressed
      WBPaper00037950:AVA-neuron_L1-larva_expressed
      WBPaper00037950:AVE-neuron_L1-larva_expressed
      WBPaper00037950:BAG-neuron_blastula-embryo_expressed
      WBPaper00037950:bodywall-muscle_L2-larva_expressed
      WBPaper00037950:coelomocytes_L2-larva_expressed
      WBPaper00037950:dopaminergic-neurons_L3-L4-larva_expressed
      WBPaper00037950:excretory-cell_L2-larva_expressed
      WBPaper00037950:GABAergic-motor-neurons_L2-larva_expressed
      WBPaper00037950:germline-precursors_blastula-embryo_expressed
      WBPaper00037950:glr-1(+)-neurons_L2-larva_expressed
      WBPaper00037950:intestine_L2-larva_expressed
      WBPaper00038289:oocyte_protein
      WBPaper00040221:DAF-12_target_ALF4
      WBPaper00044736:flat_dev_expression
      WBPaper00044746:aging_upregulated_HeatShock
      WBPaper00045420:fertilization_downregulated_transcript
      WBPaper00045521:Gender_Neutral
      WBPaper00045974:NSM_enriched_totalRNA_RNAseq
      WBPaper00048988:neuron_expressed
      WBPaper00049018:SWSN-2.2_interacting
      WBPaper00049545:jmjd-3.1(+)_downregulated
      WBPaper00049545:sur-5p-jmjd-1.2(+)_downregulated
      WBPaper00049942:hsf-1(RNAi)_upregulated
      WBPaper00050344:PLM-neuron_enriched
      WBPaper00050488:adult_vs_dauer_regulated_N2_20C
      WBPaper00050636:aging_regulated_insoluble_protein
      WBPaper00050698:DEP-1_interacting
      WBPaper00050726:OsmoticStress_regulated_Food
      WBPaper00050726:starvation_regulated_LowSalt
      WBPaper00050990:body-muscle_expressed
      WBPaper00050990:GABAergic-neuron_expressed
      WBPaper00050990:hypodermis_expressed
      WBPaper00050990:intestine_expressed
      WBPaper00050990:NMDA-neuron_expressed
      WBPaper00050990:pharynx_expressed
      WBPaper00051039:germline_enriched
      WBPaper00051245:body-wall-muscle_cytoplasm_expressed
      WBPaper00051245:cytoplasm_specific
      WBPaper00051245:epidermis_cytoplasm_expressed
      WBPaper00051245:epidermis_nucleus_expressed
      WBPaper00051245:intestine_cytoplasm_expressed
      WBPaper00051245:pharyngeal-muscle_cytoplasm_expressed
      WBPaper00051555:atm-1(gk186)_regulated_protein
      WBPaper00051558:aging_regulated
      WBPaper00052884:emb-4(hc60)_downregulated
      WBPaper00053184:sma-2(rax5)_downregulated
      WBPaper00053184:sma-4(rax3)_downregulated
      WBPaper00053388:dauer_regulated_Cluster6
      WBPaper00053606:N2_vs_elt-2(ca15);elt-7(tm840)_upregulated
      WBPaper00053615:SMO-1_target
      WBPaper00053810:daf-2(e1370)_downregulated
      WBPaper00053810:isp-1(qm150)_downregulated
      WBPaper00053810:nuo-6(qm200)_downregulated
      WBPaper00055648:germline_expressed
      WBPaper00055971:nhl-2(ok818)_25C_upregulated
      WBPaper00056090:E.faecalis_downregulated_hpx-2(dg047)
      WBPaper00056471:S.aureus-4h_downregulated_N2
      WBPaper00056826:SGP_biased
      WBPaper00057288:iff-1(RNAi)_downregulated_transcript
      WBPaper00059356:BAZ-2_SET-6_interacting
      WBPaper00059356:set-6(ok2195)_baz-2(tm0235)_regulated
      WBPaper00059471:EGL-43_interacting
      WBPaper00061340:ADA_ADE_grandparent
      WBPaper00061340:AVE
      WBPaper00061377:MYRF-1_interacting
      WBPaper00061439:unc-30(ok613)_upregulated
      WBPaper00061478:SUMO-conjugated_protein
      WBPaper00061527:dld-1-skn-1_16701
      WBPaper00062143:PQN-59_interacting
      WBPaper00062554:MAGU-2_interacting
      WBPaper00062590:Aging_downregulated_hypodermis
      WBPaper00062669:extracellular-vesicle_protein
      WBPaper00064071:NHR-49_interacting
      WBPaper00064716:paraquat_upregulated
      WBPaper00065120:body-muscle-transcriptome
      WBPaper00065373:Cisplatin_upregulated_WT
      WBPaper00065373:sek-1(km4)_upregulated_cisplatin
      WBPaper00065975:P-body_vs_oocyte_depleted
      cgc4489_group_21
      WBPaper00025141:N2_Expressed_Genes
      WBPaper00026980:intestine_enriched
      WBPaper00031832:slr-2_regulated
      WBPaper00032948:FedUp
      WBPaper00040858:eQTL_age_regulated_developing
      WBPaper00040858:eQTL_regulated_developing
      WBPaper00041606:CE_X.nematophila_regulated
      WBPaper00053236:Starvation_regulated_GR1307
      WBPaper00053236:Starvation_regulated_N2
    Interaction (67)
  Map_info: Map: II Position: 24.073 Error: 0.044205
    Positive: Positive_clone: Y53F4B Inferred_automatically: From sequence, transcript, pseudogene data
    Pseudo_map_position
  Reference (12)
  Remark: Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. CGC_data_submission
  Method: Gene