slcf-1 encodes a plasma membrane transporter that is a member of the conserved monocarboxylate transporter family; loss of SLCF-1 function results in altered mitochondrial metabolism, reactive oxygen species accumulation, and increased lifespan that mimics dietary restriction; an SLCF-1::GFP reporter fusion is expressed in intestinal cells during embryonic, larval and adult stages and localizes to the basolateral plasma membrane.
Predicted to enable monocarboxylic acid transmembrane transporter activity. Predicted to be involved in monocarboxylic acid transport. Located in basolateral plasma membrane. Expressed in intestine.
Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC.