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WormBase Tree Display for Gene: WBGene00010340

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Name Class

WBGene00010340SMapS_parentSequenceCHROMOSOME_X
IdentityVersion2
NameCGC_nameslcf-1Person_evidenceWBPerson605
Sequence_nameF59F5.1
Molecular_nameF59F5.1
F59F5.1.1
CE41326
Other_nameCELE_F59F5.1Accession_evidenceNDBBX284606
Public_nameslcf-1
DB_infoDatabaseAceViewgeneXL147
WormQTLgeneWBGene00010340
WormFluxgeneWBGene00010340
NDBlocus_tagCELE_F59F5.1
PanthergeneCAEEL|WormBase=WBGene00010340|UniProtKB=G5ECR3
familyPTHR11360
NCBIgene186633
RefSeqproteinNM_077361.5
TrEMBLUniProtAccG5ECR3
UniProt_GCRPUniProtAccG5ECR3
SpeciesCaenorhabditis elegans
HistoryVersion_change126 May 2004 16:54:51WBPerson1971EventImportedInitial conversion from CDS class of WS125
201 Oct 2010 14:24:45WBPerson2970Name_changeCGC_nameslcf-1
StatusLive
Gene_infoBiotypeSO:0001217
Gene_classslcf
Allele (63)
RNASeq_FPKM (74)
GO_annotation00012371
00012372
00012373
00012374
00012375
00117775
00117776
Ortholog (28)
ParalogWBGene00003986Caenorhabditis elegansFrom_analysisTreeFam
Panther
WormBase-Compara
WBGene00008214Caenorhabditis elegansFrom_analysisTreeFam
Panther
WormBase-Compara
WBGene00020168Caenorhabditis elegansFrom_analysisTreeFam
Panther
WormBase-Compara
WBGene00015676Caenorhabditis elegansFrom_analysisPanther
WormBase-Compara
WBGene00010834Caenorhabditis elegansFrom_analysisPanther
WormBase-Compara
WBGene00015273Caenorhabditis elegansFrom_analysisTreeFam
Panther
WormBase-Compara
WBGene00021227Caenorhabditis elegansFrom_analysisTreeFam
WormBase-Compara
WBGene00013353Caenorhabditis elegansFrom_analysisPanther
WormBase-Compara
WBGene00017369Caenorhabditis elegansFrom_analysisPanther
WormBase-Compara
Structured_descriptionConcise_descriptionslcf-1 encodes a plasma membrane transporter that is a member of the conserved monocarboxylate transporter family; loss of SLCF-1 function results in altered mitochondrial metabolism, reactive oxygen species accumulation, and increased lifespan that mimics dietary restriction; an SLCF-1::GFP reporter fusion is expressed in intestinal cells during embryonic, larval and adult stages and localizes to the basolateral plasma membrane.Paper_evidenceWBPaper00037741
WBPaper00041028
Curator_confirmedWBPerson1843
Date_last_updated15 May 2014 00:00:00
Automated_descriptionPredicted to enable monocarboxylic acid transmembrane transporter activity. Predicted to be involved in monocarboxylic acid transport. Located in basolateral plasma membrane. Expressed in intestine.Paper_evidenceWBPaper00065943
Curator_confirmedWBPerson324
WBPerson37462
Inferred_automaticallyThis description was generated automatically by a script based on data from the WS291 version of WormBase
Date_last_updated29 Nov 2023 00:00:00
Molecular_infoCorresponding_CDSF59F5.1
Corresponding_CDS_historyF59F5.1:wp178
Corresponding_transcriptF59F5.1.1
Other_sequenceJI221829.1
HBC09062_1
EX828307.1
Acan_isotig19085
ACC04198_1
Acan_isotig13148
ES743270.1
Associated_featureWBsf648482
Experimental_infoRNAi_result (25)
Expr_patternExpr9155
Expr1013235
Expr1152966
Expr2015879
Expr2034112
Drives_constructWBCnstr00013752
WBCnstr00014891
WBCnstr00031488
Construct_productWBCnstr00013752
WBCnstr00031488
Microarray_results (19)
Expression_clusterWBPaper00033065:cyc-1(RNAi)_upregulated
WBPaper00037950:bodywall-muscle_L1-larva_expressed
WBPaper00037950:intestine_L1-larva_expressed
WBPaper00037950:intestine_L2-larva_expressed
WBPaper00037950:intestine_larva_enriched
WBPaper00037950:intestine_larva_SelectivelyEnriched
WBPaper00038168:lin-35_upregulated
WBPaper00038438:D.coniospora_12hr_downregulated_RNAseq
WBPaper00038438:S.marcescens_24hr_upregulated_RNAseq
WBPaper00038438:S.marcescens_24hr_upregulated_TilingArray
WBPaper00044037:eat-2_upregulated
WBPaper00044656:tatn-1(qd182)_upregulated
WBPaper00044736:flat_dev_expression
WBPaper00045934:wrn-1(gk99)_upregulated
WBPaper00048988:neuron_expressed
WBPaper00049545:jmjd-3.1(+)_upregulated
WBPaper00049545:rgef-1p-jmjd-1.2(+)_upregulated
WBPaper00050080:rbr-2(tm3141)_upregulated
WBPaper00050163:chd-3(eh4)_downregulated_100-cell-embryo
WBPaper00050370:dpy-21(e428)_L3_upregulated
WBPaper00050488:adult_vs_dauer_regulated_N2_20C
WBPaper00050488:mir-34(gk437)_vs_mir-34(OverExpression)_regulated_dauer_20C
WBPaper00050488:N2_vs_mir-34(gk437)_regulated_dauer_20C
WBPaper00050488:N2_vs_mir-34(OverExpression)_regulated_adult_25C
WBPaper00050726:OsmoticStress_regulated_NoFood
WBPaper00050859:upregulated_P-granule(-)GFP(+)_vs_control_day2-adult
WBPaper00050859:upregulated_P-granule(-)GFP(-)_vs_control_day2-adult
WBPaper00050990:intestine_enriched
WBPaper00050990:intestine_expressed
WBPaper00051039:intestine_enriched
WBPaper00053302:stavudine_24h_regulated
WBPaper00053302:zidovudine_72h_regulated
WBPaper00053388:dauer_regulated_Cluster1
WBPaper00053606:elt-2(ca15)_vs_elt-2(ca15);elt-7(tm840)_doenregulated
WBPaper00053606:N2_vs_elt-2(ca15)_upregulated
WBPaper00055060:flr-1(RNAi)_upregulated
WBPaper00055354:eat-2(ad1116)_downregulated
WBPaper00055354:Psora-Allantoin_downregulated
WBPaper00055354:Rapamycin-Metformin_downregulated
WBPaper00055354:Rapamycin-Rifampicin-Allantoin_downregulated
WBPaper00055354:Rapamycin-Rifampicin_downregulated
WBPaper00055354:Rifampicin-Allantoin_downregulated
WBPaper00055354:Rifampicin_downregulated
WBPaper00055971:nhl-2(ok818)_25C_downregulated
WBPaper00056167:Cry5B_downregulated
WBPaper00056293:rpl-5(0)-rpl-33(0)_upregulated
WBPaper00056826:hmc_biased
WBPaper00056997:nmad-1(ok3133)_upregulated_germline_25C
WBPaper00057143:ztf-11(RNAi)_upregulated
WBPaper00058598:spn-4(tm291)_upregulated
WBPaper00058711:paraquat_downregulated
WBPaper00058948:PA14_downregulated
WBPaper00059328:mrps-5(RNAi)_upregulated_mRNA
WBPaper00059567:olrn-1(ums9)_regulated
WBPaper00059664:srbc-48(ac23)_upregulated
WBPaper00059895:wounding_upregulated
WBPaper00060358:B.thuringiensis_pathogen_regulated_elt-2(RNAi)
WBPaper00060358:B.thuringiensis_pathogen_regulated_N2
WBPaper00060661:sensory-neuron_depleted
WBPaper00060909:atfs-1(cmh15)_downregulated
WBPaper00061007:HB101_upregulated
WBPaper00061007:S.aquatilis_upregulated
WBPaper00061527:col-128-cdh-10_9234
WBPaper00062159:hda-2(ok1479)_upregulated
WBPaper00062193:skn-1(RNAi)_downregulated
WBPaper00062325:muscle_depleted_coding-RNA
WBPaper00064005:starvation_upregulated_N2_mRNA
WBPaper00064088:Day-1-adult_vs_L4_downregulated_daf-16(mu86);glp-1(e2141)
WBPaper00064088:Day-3-adult_vs_L4_downregulated_fem-3(q20)
WBPaper00064505:tamoxifen_downregulated
WBPaper00064716:paraquat_downregulated
WBPaper00064933:bcf-1(ylf1)_downregulated_transcript
WBPaper00065096:25C_vs_20C_downregulated
WBPaper00065096:Day10_vs_Day1_downregulated
WBPaper00065258:anchor-cell_depleted
WBPaper00065993:glp-1(e2141)_upregulated
WBPaper00066232:ash-2(RNAi)_downregulated_WT
WBPaper00066232:hsf-1(RNAi)_upregulated_ash-2
WBPaper00026929:Resveratrol_regulated_daf-16
WBPaper00036286:Pattern_I
WBPaper00040858:eQTL_regulated_old
WBPaper00046853:AOBr_M.aeruginosa-batch-culture_downregulated
WBPaper00048637:lin-35(n745)_starvation_upregulated
WBPaper00048989:eat-2(ad465)_downregulated_in-DMSO
WBPaper00048989:N2_rapamycin_upregulated
Interaction (14)
Map_infoMapXPosition2.22549Error0.000129
PositivePositive_cloneF59F5Inferred_automaticallyFrom sequence, transcript, pseudogene data
Pseudo_map_position
ReferenceWBPaper00031805
WBPaper00037741
WBPaper00045256
WBPaper00045338
WBPaper00046800
WBPaper00047404
WBPaper00062255
WBPaper00064057
RemarkMap position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC.CGC_data_submission
MethodGene