WormBase Tree Display for Gene: WBGene00004490

WBGene00004490 SMap: S_parent: Sequence: F37C12
  Identity: Version: 1
    Name: CGC_name: rps-21
      Sequence_name: F37C12.11
      Molecular_name: F37C12.11
        F37C12.11.1
        CE30779
      Other_name: CELE_F37C12.11 Accession_evidence: NDB BX284603
      Public_name: rps-21
    DB_info: Database: AceView gene 3I278
        WormQTL gene WBGene00004490
        WormFlux gene WBGene00004490
        NDB locus_tag CELE_F37C12.11
        Panther gene CAEEL|WormBase=WBGene00004490|UniProtKB=P49197
          family PTHR10442
        NCBI gene 176011
        RefSeq protein NM_066178.10
        SwissProt UniProtAcc P49197
        TREEFAM TREEFAM_ID TF300167
        UniProt_GCRP UniProtAcc P49197
    Species: Caenorhabditis elegans
    History: Version_change: 1 07 Apr 2004 11:29:35 WBPerson1971 Event: Imported: Initial conversion from geneace
    Status: Live
  Gene_info: Biotype: SO:0001217
    Gene_class: rps
    Allele: WBVar01500260
      WBVar01645365
      WBVar01499774
      WBVar01825495
      WBVar01499237
      WBVar02053330
      WBVar00837914
      WBVar00837915
      WBVar00837916
      WBVar00401240
    Legacy_information: Orthologous to yeast (S.cerevisiae) ribosomal protein rps21 using blastP
    RNASeq_FPKM (74)
    GO_annotation (15)
    Ortholog (35)
    Structured_description: Concise_description: rps-21 encodes a small ribosomal subunit S21 protein; by homology, RPS-21 is predicted to function in protein biosynthesis; in C. elegans, RPS-21 activity is required for embryonic and germline development, as well as the overall health of the animal. Paper_evidence (2)
          Curator_confirmed: WBPerson1843
          Date_last_updated: 17 Jun 2004 00:00:00
      Automated_description: Predicted to be a structural constituent of ribosome. Predicted to be involved in endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) and endonucleolytic cleavage to generate mature 3'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA). Predicted to be located in cytosol; ribosome; and rough endoplasmic reticulum. Predicted to be part of cytosolic small ribosomal subunit. Is an ortholog of human RPS21 (ribosomal protein S21). Paper_evidence: WBPaper00065943
          Curator_confirmed: WBPerson324
            WBPerson37462
          Inferred_automatically: This description was generated automatically by a script based on data from the WS291 version of WormBase
          Date_last_updated: 29 Nov 2023 00:00:00
  Molecular_info: Corresponding_CDS: F37C12.11
    Corresponding_transcript: F37C12.11.1
    Other_sequence (285)
    Associated_feature: WBsf651180
      WBsf667046
      WBsf992955
      WBsf1015202
      WBsf226926
      WBsf226927
  Experimental_info: RNAi_result (29)
    Expr_pattern: Chronogram728
      Chronogram1946
      Expr5980
      Expr1011153
      Expr1032293
      Expr1150488
      Expr2015516
      Expr2033751
    Drives_construct: WBCnstr00003591
      WBCnstr00035445
    Construct_product: WBCnstr00035445
    Microarray_results (21)
    Expression_cluster: WBPaper00005700:secreted_protein
      WBPaper00031040:TGF-beta_adult_downregulated
      WBPaper00032528:L3_enriched
      WBPaper00036662:oxidative_modification
      WBPaper00037047:aging_accelerated_insoluble_protein
      WBPaper00037047:insoluble_protein
      WBPaper00037682:sma-2_downregulated
      WBPaper00037950:all-neurons_L2-larva_expressed
      WBPaper00037950:BAG-neuron_blastula-embryo_expressed
      WBPaper00037950:bodywall-muscle_L2-larva_expressed
      WBPaper00037950:CEP-sheath-cells_Day1-adult_expressed
      WBPaper00037950:germline-precursors_blastula-embryo_expressed
      WBPaper00037950:hypodermis_L3-L4-larva_expressed
      WBPaper00037950:intestine_L1-larva_expressed
      WBPaper00037950:PVD-OLL-neurons_L3-L4-larva_expressed
      WBPaper00038118:aak-2(gt33)_downregulated
      WBPaper00038118:stress_downregulated_N2
      WBPaper00038289:oocyte_protein
      WBPaper00038438:D.coniospora_12hr_upregulated_RNAseq
      WBPaper00038438:S.marcescens_24hr_downregulated_RNAseq
      WBPaper00044426:rotenone_24h_upregulated
      WBPaper00044501:gld-1_let-7_regulated
      WBPaper00044736:flat_dev_expression
      WBPaper00044746:aging_downregulated_HeatShock
      WBPaper00045050:drh-3 (ne4253)_downregulated
      WBPaper00045303:ZK1236.1(tm4178)_downregulated
      WBPaper00045521:Gender_Neutral
      WBPaper00045571:germline-ablation_downregulated
      WBPaper00046497:B.thuringiensis_0.1mix_downregulated_6h
      WBPaper00048910:Apoptosis-induced_mRNA-interacting_protein
      WBPaper00048910:mRNA-interacting_protein
      WBPaper00048923:Aging_regulated
      WBPaper00048926:miaserin_upregulated_adult-day5
      WBPaper00048988:neuron_expressed
      WBPaper00049018:swsn-2.2(RNAi)_downregulated
      WBPaper00049217:DAF-16_downregulated
      WBPaper00049498:npr-1(ur89)_regulated_3
      WBPaper00049545:cco-1(RNAi)_downregulated
      WBPaper00049545:jmjd-3.1(+)_downregulated
      WBPaper00049545:sur-5p-jmjd-1.2(+)_downregulated
      WBPaper00049942:HeatShock_downregulated_hsf-1(RNAi)
      WBPaper00049942:HeatShock_upregulated_hsf-1(+)
      WBPaper00050234:lin-28(RNAi)_downregulated
      WBPaper00050344:ASER-neuron_enriched
      WBPaper00050488:adult_vs_dauer_regulated_N2_20C
      WBPaper00050488:mir-34(OverExpression)_vs_N2_regulated_adult_20C
      WBPaper00050488:N2_vs_mir-34(OverExpression)_regulated_adult_25C
      WBPaper00050698:DEP-1_interacting
      WBPaper00050726:OsmoticStress_regulated_Food
      WBPaper00050726:OsmoticStress_regulated_NoFood
      WBPaper00050859:downregulated_P-granule(-)GFP(+)_vs_control_day2-adult
      WBPaper00050859:downregulated_P-granule(-)GFP(-)_vs_control_day2-adult
      WBPaper00051039:germline_enriched
      WBPaper00051245:epidermis_cytoplasm_expressed
      WBPaper00051245:epidermis_nucleus_expressed
      WBPaper00051245:intestine_cytoplasm_expressed
      WBPaper00051265:F4_morc-1(tm6048)_downregulated
      WBPaper00051555:atm-1(gk186)_regulated_protein
      WBPaper00052884:emb-4(hc60)_upregulated
      WBPaper00053184:sma-2(rax5)_downregulated
      WBPaper00053184:sma-4(rax3)_downregulated
      WBPaper00053289:DREAM-target
      WBPaper00053295:lin-22(ot269)_downregulated
      WBPaper00053388:dauer_regulated_Cluster6
      WBPaper00053810:isp-1(qm150)_downregulated
      WBPaper00054996:activated_sperm_CE
      WBPaper00054996:membranous_oraganelle_CE
      WBPaper00055060:flr-1(RNAi)_downregulated
      WBPaper00055354:Psora-Allantoin_downregulated
      WBPaper00055354:Rapamycin-Metformin_downregulated
      WBPaper00055354:Rapamycin-Rifampicin-Allantoin_downregulated
      WBPaper00055354:Rapamycin-Rifampicin_downregulated
      WBPaper00055354:Rifampicin_downregulated
      WBPaper00055648:germline_expressed
      WBPaper00055827:daf-2(e1370)_downregulated
      WBPaper00055897:heat-shock_upregulated
      WBPaper00056471:S.aureus-4h_downregulated_N2
      WBPaper00056826:SGP_biased
      WBPaper00056900:ERH-2_interacting
      WBPaper00056900:PID-3_interacting
      WBPaper00056900:TOFU-6_interacting
      WBPaper00056900:TOST-1_interacting
      WBPaper00056997:nmad-1(ok3133)_downregulated_germline_25C
      WBPaper00056997:NMAD-1_interacting
      WBPaper00057083:daf-2(e1370)rsks-1(ok1255)_post-transcriptional_downregulated
      WBPaper00058691:set-2(bn129)_downregulated
      WBPaper00058711:wdr-5(ok1417)_downregulated
      WBPaper00059254:CSR-1_interacting
      WBPaper00059254:PRG-1_interacting
      WBPaper00059254:WAGO-1_interacting
      WBPaper00059471:EGL-43_interacting
      WBPaper00059605:MUT-16_interacting
      WBPaper00060100:SiNP_downregulated_mRNA
      WBPaper00060811:L1_vs_adult_downregulated_neural
      WBPaper00061340:M_cell
      WBPaper00061341:28C_24h_downregulated
      WBPaper00061341:28C_48h_downregulated
      WBPaper00061377:MYRF-1_interacting
      WBPaper00061377:MYRF-2_interacting
      WBPaper00061377:PAN-1_interacting
      WBPaper00061390:daf-22(ok693)_ascarosides_downregulated
      WBPaper00061439:unc-30(ok613)_upregulated
      WBPaper00061439:unc-30(ok613)_upregulated_P.aeruginosa-infection
      WBPaper00061527:rps-14_21270-rps-11_20714
      WBPaper00061530:nhr-49(e2144)_downregulated
      WBPaper00061651:ADA_enriched
      WBPaper00061651:Distal_tip_cell_enriched
      WBPaper00061651:Germline_enriched
      WBPaper00061651:I3_enriched
      WBPaper00061651:I4_enriched
      WBPaper00061651:M2_enriched
      WBPaper00061651:PVM_enriched
      WBPaper00061651:RIG_enriched
      WBPaper00061651:RIH_enriched
      WBPaper00061651:Spermatheca_enriched
      WBPaper00061651:URB_enriched
      WBPaper00061818:AFD_enriched_protein
      WBPaper00061818:ELKS-1_interacting
      WBPaper00062002:Day4-adult_secretome
      WBPaper00062143:PQN-59_interacting
      WBPaper00062159:hda-2(ok1479)_upregulated
      WBPaper00062193:skn-1(RNAi)_upregulated
      WBPaper00062325:etr-1(lq61)_downregulated
      WBPaper00062325:muscle_enriched_coding-RNA
      WBPaper00062498:PPM-1.D_interacting
      WBPaper00062554:MAGU-2_interacting
      WBPaper00062669:extracellular-vesicle_protein
      WBPaper00064055:trl-1(cas1077)_downregulated_non-starved
      WBPaper00064055:trl-1(cas1077)_downregulated_starved
      WBPaper00064071:NHR-49_interacting
      WBPaper00064080:miR-2_miRNA_interacting
      WBPaper00064088:Day-3-adult_vs_L4_downregulated_glp-1(e2141)
      WBPaper00064163:ZNFX-1_interacting_embryo
      WBPaper00064315:mrg-1(qa6200)_downregulated_PGCs
      WBPaper00064727:daf-2(e1370)_downregulated
      WBPaper00064933:E.coli-binding_secret_protein
      WBPaper00065149:lin-52(n771)_downregulated
      WBPaper00065373:Cisplatin_downregulated_WT
      WBPaper00065975:P-body_vs_oocyte_depleted
      WBPaper00065975:P-body_vs_WholeAnimal_depleted
      WBPaper00066085:hda-3(ok1991)_downregulated
      WBPaper00066085:sin-3(syb2172)_downregulated
      cgc4489_group_1
      WBPaper00024393:strongly_regulated_dauer_genes
      WBPaper00024671:AFD_AWB_vs_unsorted_downregulated
      WBPaper00025032:cluster_10
      WBPaper00025141:N2_Expressed_Genes
      WBPaper00025141:unc-4::GFP_Expressed_Genes
      WBPaper00026929:Resveratrol_regulated_daf-16
      WBPaper00026929:sir-2.1_overexpression_regulated
      WBPaper00026980:intestine_enriched
      WBPaper00028564:CeMM_vs_NGM_upregulated
      WBPaper00031003:hlh_1_enriched
      WBPaper00034739:N2moreDR1350
      WBPaper00036123:Atrazine_regulated
      WBPaper00041174:environmental
      WBPaper00041174:environmental_prime
      WBPaper00041606:CE_B.thuringiensis-DB27_regulated
      WBPaper00041606:CE_S.marcescens_regulated
      WBPaper00048989:eat-2(ad465)_downregulated_in-DMSO
      WBPaper00048989:N2_rapamycin_upregulated
      WBPaper00053236:Starvation_regulated_N2
      [cgc5767]:cluster_5
      [cgc5767]:expression_class_E
      [cgc5767]:expression_class_E_pi(66_min)
      [cgc5767]:expression_class_M
      [cgc5767]:expression_class_ME
    Interaction (260)
  Map_info: Map: III Position: -0.775211 Error: 0.000213
    Positive: Positive_clone: F37C12 Inferred_automatically: From CDS info
            From sequence, transcript, pseudogene data
    Pseudo_map_position
  Reference: WBPaper00028564
    WBPaper00033090
    WBPaper00035215
    WBPaper00035286
    WBPaper00038491
    WBPaper00049828
    WBPaper00055090
  Remark: Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. CGC_data_submission
  Method: Gene