WormBase Tree Display for Gene: WBGene00002250

WBGene00002250 SMap: S_parent: Sequence: W07G4
  Identity: Version: 2
    Name: CGC_name: lap-2 Paper_evidence: WBPaper00004658
      Sequence_name: W07G4.4
      Molecular_name: W07G4.4
        W07G4.4.1
        CE03794
      Other_name: CELE_W07G4.4 Accession_evidence: NDB BX284605
      Public_name: lap-2
    DB_info: Database (11)
    Species: Caenorhabditis elegans
    History: Version_change: 1 07 Apr 2004 11:29:27 WBPerson1971 Event: Imported: Initial conversion from geneace
        2 16 Jun 2011 09:26:20 WBPerson2970 Event: Acquires_merge: WBGene00012338
              Name_change: Sequence_name: W07G4.4
      Acquires_merge: WBGene00012338
    Status: Live
  Gene_info: Biotype: SO:0001217
    Gene_class: lap
    Allele (29)
    Strain: WBStrain00036935
    RNASeq_FPKM (74)
    GO_annotation (14)
    Ortholog (32)
    Paralog: WBGene00002249 Caenorhabditis elegans From_analysis: Panther
            WormBase-Compara
    Structured_description: Concise_description: The lap-2 gene encodes a homolog of the zinc metalloprotease leucine aminopeptidase LAP. Paper_evidence: WBPaper00004658
          Curator_confirmed: WBPerson567
          Date_last_updated: 17 Jun 2004 00:00:00
      Automated_description: Predicted to enable peptidase activity. Predicted to be involved in proteolysis. Predicted to be located in cytoplasm. Paper_evidence: WBPaper00065943
          Curator_confirmed: WBPerson324
            WBPerson37462
          Inferred_automatically: This description was generated automatically by a script based on data from the WS291 version of WormBase
          Date_last_updated: 29 Nov 2023 00:00:00
  Molecular_info: Corresponding_CDS: W07G4.4
    Corresponding_transcript: W07G4.4.1
    Other_sequence (127)
    Associated_feature: WBsf982020
      WBsf1001701
      WBsf232734
      WBsf232735
  Experimental_info: RNAi_result (3)
    Expr_pattern: Expr1031324
      Expr1158497
      Expr2013011
      Expr2031243
    Drives_construct: WBCnstr00036360
    Construct_product: WBCnstr00036360
    Microarray_results (17)
    Expression_cluster: WBPaper00031040:TGF-beta_adult_downregulated
      WBPaper00032528:L3_enriched
      WBPaper00033065:cyc-1(RNAi)_upregulated
      WBPaper00035073:mitochondria_protein
      WBPaper00035926:A.hydrophila_regulated
      WBPaper00035963:S.aureus_8h_upregulated
      WBPaper00036375:enriched_in_PVD_OLL
      WBPaper00037950:AVE-neuron_L1-larva_expressed
      WBPaper00037950:CEP-sheath-cells_Day1-adult_expressed
      WBPaper00037950:coelomocytes_L1-larva_expressed
      WBPaper00037950:coelomocytes_L2-larva_expressed
      WBPaper00037950:dopaminergic-neurons_L3-L4-larva_expressed
      WBPaper00037950:excretory-cell_L2-larva_expressed
      WBPaper00037950:GABAergic-motor-neurons_L2-larva_expressed
      WBPaper00037950:germline-precursors_blastula-embryo_expressed
      WBPaper00037950:hypodermis_L3-L4-larva_expressed
      WBPaper00037950:intestine_L1-larva_expressed
      WBPaper00037950:intestine_L2-larva_expressed
      WBPaper00037950:PVD-OLL-neurons_L3-L4-larva_expressed
      WBPaper00038118:aak-2(gt33)_upregulated
      WBPaper00038289:oocyte_protein
      WBPaper00040755:LRRK2(G2019S)-Tau_vs_Tau_upregulated
      WBPaper00040755:Tau_vs_N2_upregulated
      WBPaper00044128:DietaryRestriction_upregulated
      WBPaper00044736:flat_dev_expression
      WBPaper00045420:fertilization_downregulated_transcript
      WBPaper00045460:Co-expression_Cluster_2
      WBPaper00045520:V.alginolyticus_upregulated
      WBPaper00045521:Gender_Neutral
      WBPaper00046497:B.thuringiensis_0.1mix_downregulated_6h
      WBPaper00046497:B.thuringiensis_0.1mix_downregulated_12h
      WBPaper00046497:B.thuringiensis_0.5mix_downregulated_6h
      WBPaper00046497:B.thuringiensis_0.5mix_downregulated_12h
      WBPaper00048910:mRNA-interacting_protein
      WBPaper00048923:Aging_regulated
      WBPaper00048988:neuron_expressed
      WBPaper00049545:sur-5p-jmjd-1.2(+)_downregulated
      WBPaper00049942:hsf-1(RNAi)_downregulated
      WBPaper00050488:20C_vs_25C_regulated_mir-34(gk437)_adult
      WBPaper00050488:20C_vs_25C_regulated_mir-34(OverExpression)_adult
      WBPaper00050488:adult_vs_dauer_regulated_N2_20C
      WBPaper00050488:N2_vs_mir-34(gk437)_regulated_dauer_20C
      WBPaper00050990:arcade_intestinal-valve_expressed
      WBPaper00050990:body-muscle_expressed
      WBPaper00050990:GABAergic-neuron_expressed
      WBPaper00050990:hypodermis_expressed
      WBPaper00050990:intestine_expressed
      WBPaper00050990:NMDA-neuron_expressed
      WBPaper00050990:pharynx_expressed
      WBPaper00050990:seam_expressed
      WBPaper00051245:epidermis_cytoplasm_expressed
      WBPaper00051404:alg-1(gk214)_downregulated
      WBPaper00051555:atm-1(gk186)_regulated_protein
      WBPaper00052884:emb-4(hc60)_downregulated
      WBPaper00053184:sma-2(rax5)_downregulated
      WBPaper00053184:sma-4(rax3)_downregulated
      WBPaper00053295:lin-22(ot269)_downregulated
      WBPaper00053321:embryo-to-L1_downregulated_nos-1(gv5)nos-2(RNAi)_SMARTseq
      WBPaper00053321:nos-1(gv5)nos-2(RNAi)_upregulated_embryo_SMARTseq
      WBPaper00053388:dauer_regulated_Cluster3
      WBPaper00054189:P.aeruginosa_regulated_protein
      WBPaper00055049:S.gordonii_upregulated
      WBPaper00055354:Psora-Allantoin_downregulated
      WBPaper00055354:Rapamycin-Metformin_downregulated
      WBPaper00055354:Rifampicin-Allantoin_downregulated
      WBPaper00055354:Rifampicin_downregulated
      WBPaper00055648:germline_expressed
      WBPaper00055862:antimycin_damt-1(gk961032)_regulated
      WBPaper00056443:sek-1(km4)_downregulated
      WBPaper00056471:S.aureus-4h_upregulated_N2
      WBPaper00057041:spc-1(cas971)_upregulated
      WBPaper00057288:iff-1(RNAi)_downregulated_transcript
      WBPaper00058691:cfp-1(tm6369)_upregulated
      WBPaper00058691:set-2(bn129)_upregulated
      WBPaper00058691:sin-3(tm1276)_upregulated
      WBPaper00058969:RIS_enriched
      WBPaper00059174:MEG-3_interacting
      WBPaper00059356:set-6(ok2195)_baz-2(tm0235)_regulated
      WBPaper00059471:EGL-43_interacting
      WBPaper00059567:olrn-1(ums9)_regulated
      WBPaper00059598:HeatShock_upregulated
      WBPaper00060084:cco-1(RNAi)_upregulated_lin-40(yth27)
      WBPaper00060084:cco-1(RNAi)_upregulated_N2
      WBPaper00060100:SiNP_upregulated_mRNA
      WBPaper00060278:atp-2(RNAi)_upregulated
      WBPaper00060358:B.thuringiensis_pathogen_regulated_elt-2(RNAi)
      WBPaper00060683:hlh-11(ko1)_upregulated
      WBPaper00060683:hlh-11(overexpression)_downregulated
      WBPaper00061274:microgravity_upregulated
      WBPaper00061340:AIB
      WBPaper00061340:AVE
      WBPaper00061340:RIM
      WBPaper00061341:28C_24h_downregulated
      WBPaper00061439:unc-30(ok613)_upregulated
      WBPaper00061478:SUMO-conjugated_protein
      WBPaper00061527:pbs-3_18439-rpn-5
      WBPaper00061651:AQR_enriched
      WBPaper00061651:ASH_enriched
      WBPaper00061651:AVE_enriched
      WBPaper00061651:PHA_enriched
      WBPaper00061651:RIM_enriched
      WBPaper00062159:hda-2(ok1479)_upregulated
      WBPaper00062669:extracellular-vesicle_protein
      WBPaper00064071:NHR-49_interacting
      WBPaper00064088:Day-1-adult_vs_L4_upregulated_daf-16(mu86);glp-1(e2141)
      WBPaper00064088:Day-1-adult_vs_L4_upregulated_fem-3(q20)
      WBPaper00064088:Day-3-adult_vs_L4_upregulated_daf-16(mu86);glp-1(e2141)
      WBPaper00064088:Day-3-adult_vs_L4_upregulated_fem-3(q20)
      WBPaper00064637:cox-5B(RNAi)_upregulated
      WBPaper00064841:tent-5(tm3504)_upregulated_protein
      WBPaper00065120:body-muscle-transcriptome
      WBPaper00065158:AFD_depleted
      WBPaper00065373:Cisplatin_upregulated_WT
      WBPaper00065841:98_0
      WBPaper00066085:sin-3(syb2172)_downregulated
      WBPaper00066085:sin-3(tm1276)_downregulated
      cgc4386_cluster_2_3
      cgc4489_group_1
      WBPaper00025032:cluster_34
      WBPaper00025141:N2_Expressed_Genes
      WBPaper00026929:sir-2.1_overexpression_regulated
      WBPaper00026980:intestine_enriched
      WBPaper00027342:alpha-Synuclein(WT)_upregulated
      WBPaper00032948:FedUp
      WBPaper00035905:FBF-1_Associated
      WBPaper00037901:GLD-1_mRNA_targets
      WBPaper00040603:tdp-1(lf)_down_vs_N2_FC_1.2
      WBPaper00040821:Au-NP_regulated
      WBPaper00041002:HF_11d_2.0mM_Up
      WBPaper00048624:hlh-25(ok1710)_upregulated
      WBPaper00049538:atfs-1(et18)_upregulated
      [cgc5767]:cluster_6
      [cgc5767]:expression_class_E
      [cgc5767]:expression_class_E_pi(101_min)
      [cgc5767]:expression_class_E_pi(122_min)
      [cgc5767]:expression_class_M
      [cgc5767]:expression_class_MD
      [cgc5767]:expression_class_MDE
      [cgc5767]:expression_class_MD_pd(23_min)
      [cgc5767]:expression_class_ME
    Interaction: WBInteraction000541850
      WBInteraction000561471
      WBInteraction000564005
      WBInteraction000573457
      WBInteraction000574494
      WBInteraction000577623
      WBInteraction000580117
      WBInteraction000582489
  Map_info: Map: V Position: 4.83267 Error: 0.008076
    Positive: Positive_clone: W07G4 Inferred_automatically: From sequence, transcript, pseudogene data
    Pseudo_map_position
  Reference: WBPaper00004658
    WBPaper00049828
    WBPaper00055090
  Remark: Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. CGC_data_submission
  Method: Gene