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WormBase Tree Display for Gene: WBGene00002249

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Name Class

WBGene00002249SMapS_parentSequenceZK353
IdentityVersion1
NameCGC_namelap-1
Sequence_nameZK353.6
Molecular_nameZK353.6
ZK353.6.1
CE00390
Other_nameCELE_ZK353.6Accession_evidenceNDBBX284603
Public_namelap-1
DB_infoDatabase (12)
SpeciesCaenorhabditis elegans
HistoryVersion_change107 Apr 2004 11:29:27WBPerson1971EventImportedInitial conversion from geneace
StatusLive
Gene_infoBiotypeSO:0001217
Gene_classlap
Allele (29)
StrainWBStrain00037216
WBStrain00008272
RNASeq_FPKM (74)
GO_annotation (20)
Contained_in_operonCEOP3520
Ortholog (42)
ParalogWBGene00002250Caenorhabditis elegansFrom_analysisPanther
WormBase-Compara
Structured_descriptionConcise_descriptionlap-1 encodes one of two C. elegans homologs of the M17 class of zinc metalloproteases, leucine aminopeptidase (LAP); lap-1 mutations result in slow growth and delayed onset of egg laying; lap-1 mRNA is present throughout the larval and adult life cycle and a lap-1 promoter fusion is expressed in the intestine; staining for LAP-1 protein reveals localization to the buccal cavity, pharynx, anterior gut and rectum.Paper_evidenceWBPaper00004658
Curator_confirmedWBPerson1843
WBPerson567
Date_last_updated15 Jun 2011 00:00:00
Automated_descriptionEnables identical protein binding activity. Involved in regulation of egg-laying behavior and regulation of growth rate. Predicted to be located in cytoplasm. Expressed in buccal cavity; intestine; and pharynx. Is an ortholog of human NPEPL1 (aminopeptidase like 1).Paper_evidenceWBPaper00065943
Curator_confirmedWBPerson324
WBPerson37462
Inferred_automaticallyThis description was generated automatically by a script based on data from the WS291 version of WormBase
Date_last_updated29 Nov 2023 00:00:00
Molecular_infoCorresponding_CDSZK353.6
Corresponding_transcriptZK353.6.1
Other_sequence (69)
Associated_featureWBsf667155
WBsf227129
WBsf227130
WBsf227131
Experimental_infoRNAi_result (15)
Expr_patternExpr889
Expr890
Expr891
Expr1021639
Expr1031323
Expr1162782
Expr2013010
Expr2031242
Drives_constructWBCnstr00013583
WBCnstr00036361
Construct_productWBCnstr00013583
WBCnstr00036361
AntibodyWBAntibody00000362
Microarray_results (19)
Expression_cluster (115)
Interaction (84)
Map_infoMapIIIPosition-0.270877Error0.001411
PositivePositive_cloneZK353Inferred_automaticallyFrom CDS info
From sequence, transcript, pseudogene data
Mapping_dataMulti_point4969
4740
5521
Pseudo_map_position
ReferenceWBPaper00004658
WBPaper00006047
WBPaper00006425
WBPaper00026640
WBPaper00038491
WBPaper00049828
WBPaper00055090
WBPaper00063976
RemarkSequence connection from [Joshua GWP]
Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC.CGC_data_submission
MethodGene