WormBase Tree Display for Gene: WBGene00001829

WBGene00001829 SMap: S_parent: Sequence: ZK1055
  Identity: Version: 1
    Name: CGC_name: hcp-1 Person_evidence: WBPerson537
      Sequence_name: ZK1055.1
      Molecular_name: ZK1055.1
        ZK1055.1.1
        CE18470
      Other_name: CELE_ZK1055.1 Accession_evidence: NDB BX284605
      Public_name: hcp-1
    DB_info: Database: AceView gene 5H79
        WormQTL gene WBGene00001829
        WormFlux gene WBGene00001829
        NDB locus_tag CELE_ZK1055.1
        Panther gene CAEEL|WormBase=WBGene00001829|UniProtKB=O76447
          family PTHR34491
        NCBI gene 179049
        RefSeq protein NM_072276.4
        TREEFAM TREEFAM_ID TF101133
        TrEMBL UniProtAcc O76447
        UniProt_GCRP UniProtAcc O76447
    Species: Caenorhabditis elegans
    History: Version_change: 1 07 Apr 2004 11:29:25 WBPerson1971 Event: Imported: Initial conversion from geneace
    Status: Live
  Gene_info: Biotype: SO:0001217
    Gene_class: hcp
    Allele (78)
    RNASeq_FPKM (74)
    GO_annotation (16)
    Ortholog (30)
    Paralog: WBGene00001830 Caenorhabditis elegans From_analysis: Inparanoid_8
            WormBase-Compara
    Structured_description: Concise_description: hcp-1 encodes a homolog of the mammalian centromere protein-F (CENP-F) and is involved in mitotic chromosome segregation; hcp-1 functions in an ordered pathway consisting of two other CENP proteins encoded by hcp-3 and hcp-4 to control assembly of the kinetochore; hcp-1 localization to the kinetochore is dependent on hcp-3 and hcp-4. Paper_evidence: WBPaper00003772
            WBPaper00004735
          Curator_confirmed: WBPerson324
            WBPerson567
          Date_last_updated: 17 Jun 2004 00:00:00
      Automated_description: Involved in chromosome segregation; organelle organization; and protein localization. Located in kinetochore; nucleus; and spindle. Expressed in AB and Psub1. Paper_evidence: WBPaper00065943
          Curator_confirmed: WBPerson324
            WBPerson37462
          Inferred_automatically: This description was generated automatically by a script based on data from the WS291 version of WormBase
          Date_last_updated: 29 Nov 2023 00:00:00
  Molecular_info: Corresponding_CDS: ZK1055.1
    Corresponding_transcript: ZK1055.1.1
    Other_sequence: CRC01217_1
      CBC04093_1
      CR00770
      FD514421.1
      CBC02068_1
      CSC00393_1
    Associated_feature: WBsf661379
      WBsf231892
      WBsf231893
  Experimental_info: RNAi_result (19)
    Expr_pattern: Expr1191
      Expr3059
      Expr1014439
      Expr1031074
      Expr1162505
      Expr1200204
      Expr2012377
      Expr2030613
    Drives_construct (2)
    Construct_product: WBCnstr00000663
      WBCnstr00000893
      WBCnstr00017306
      WBCnstr00020451
      WBCnstr00036662
    Antibody: WBAntibody00000249
      WBAntibody00002971
    Microarray_results (18)
    Expression_cluster: WBPaper00028451:Oogenic_protein
      WBPaper00031040:TGF-beta_adult_downregulated
      WBPaper00033065:cyc-1(RNAi)_downregulated
      WBPaper00037047:aging_accelerated_insoluble_protein
      WBPaper00037047:insoluble_protein
      WBPaper00037950:BAG-neuron_blastula-embryo_expressed
      WBPaper00037950:CEP-sheath-cells_Day1-adult_expressed
      WBPaper00037950:dopaminergic-neurons_L1-larva_expressed
      WBPaper00037950:dopaminergic-neurons_L3-L4-larva_expressed
      WBPaper00037950:GABAergic-motor-neurons_L1-larva_expressed
      WBPaper00037950:hypodermis_L1-larva_expressed
      WBPaper00037950:hypodermis_L3-L4-larva_expressed
      WBPaper00037950:intestine_L1-larva_expressed
      WBPaper00037950:pharyngeal-muscle_L1-larva_expressed
      WBPaper00037950:PVD-OLL-neurons_L3-L4-larva_expressed
      WBPaper00044426:rotenone_24h_downregulated
      WBPaper00044501:gld-1_let-7_regulated
      WBPaper00044656:tatn-1(qd182)_downregulated
      WBPaper00044736:flat_dev_expression
      WBPaper00045521:Gender_Neutral
      WBPaper00046337:monosomal_N2_vs_daf-2_upregulated
      WBPaper00046337:polysomal_daf-2_vs_daf-2;daf-16_upregulated
      WBPaper00046497:B.thuringiensis_0.1mix_downregulated_12h
      WBPaper00046497:B.thuringiensis_0.5mix_downregulated_6h
      WBPaper00046497:B.thuringiensis_0.5mix_downregulated_12h
      WBPaper00046499:AMPK_regulated
      WBPaper00046509:htz-1(ok3099)_upregulated
      WBPaper00046509:lin-35(n745)_upregulated
      WBPaper00048611:MnCl2_downregulated
      WBPaper00048785:heat-shock_upregulated
      WBPaper00048988:neuron_expressed
      WBPaper00049498:npr-1(ur89)_regulated_6
      WBPaper00049920:Glucose-Diet_downregulated_hyl-2(tm2031)
      WBPaper00049920:Glucose-Diet_downregulated_N2
      WBPaper00049942:HeatShock_upregulated_hsf-1(RNAi)
      WBPaper00049942:hsf-1(RNAi)_upregulated
      WBPaper00050193:cec-4(ok3124)_downregulated_L1
      WBPaper00050193:met-2(n4256)set-25(n5021)_downregulated_L1
      WBPaper00050225:flp-6(RNAi)_upregulated
      WBPaper00050488:adult_vs_dauer_regulated_N2_20C
      WBPaper00050488:mir-34(gk437)_vs_mir-34(OverExpression)_regulated_dauer_20C
      WBPaper00050522:mafr-1(tm6082)_downregulated
      WBPaper00050686:glp-1(e2141)_downregulated
      WBPaper00050726:OsmoticStress_regulated_Food
      WBPaper00050726:OsmoticStress_regulated_NoFood
      WBPaper00050859:downregulated_P-granule(-)GFP(+)_vs_control_day2-adult
      WBPaper00050990:arcade_intestinal-valve_expressed
      WBPaper00050990:hypodermis_expressed
      WBPaper00050990:NMDA-neuron_expressed
      WBPaper00051039:germline_enriched
      WBPaper00051265:F1_morc-1(tm6048)_downregulated
      WBPaper00052884:emb-4(hc60)_downregulated
      WBPaper00053184:sma-2(rax5)_downregulated
      WBPaper00053184:sma-4(rax3)_downregulated
      WBPaper00053289:DREAM-target
      WBPaper00053302:alovudine_24h_regulated
      WBPaper00053302:stavudine_24h_regulated
      WBPaper00053302:zidovudine_24h_regulated
      WBPaper00053302:zidovudine_72h_regulated
      WBPaper00053713:Pheromone-induced_postdauer_vs_control_upregulated
      WBPaper00053713:Starvation-induced_postdauer_vs_control_downregulated
      WBPaper00053810:nuo-6(qm200)_downregulated
      WBPaper00055103:thoc-5(wy822)_downregulated
      WBPaper00055226:ADR-2_target_N2
      WBPaper00055334:DLC-1_interacting
      WBPaper00055354:Rapamycin-Metformin_upregulated
      WBPaper00055626:pry-1(mu38)_upregulated
      WBPaper00055648:germline_expressed
      WBPaper00055648:sperm_expressed
      WBPaper00055862:antimycin_damt-1(gk961032)_regulated
      WBPaper00055971:nhl-2(ok818)_25C_upregulated
      WBPaper00056090:E.faecalis_downregulated_hpx-2(dg047)
      WBPaper00056161:hermaphrodite_enriched_siRNA
      WBPaper00056165:MINA-1_interacting_mRNA
      WBPaper00056284:ints-5(RNAi)_downregulated
      WBPaper00056290:hsp-6(mg585)_downregulated
      WBPaper00056293:rpl-5(0)-rpl-33(0)_downregulated
      WBPaper00056443:sek-1(km4)_downregulated
      WBPaper00056471:aak-1(tm1944);aak-2(ok524)_downregulated
      WBPaper00056826:hmc_biased
      WBPaper00056997:NMAD-1_interacting
      WBPaper00057041:spc-1(cas971)_upregulated
      WBPaper00057154:HeatShock_downregulated_mRNA
      WBPaper00057288:iff-1(RNAi)_downregulated_transcript
      WBPaper00058691:cfp-1(tm6369)_downregulated
      WBPaper00058691:set-2(bn129)_downregulated
      WBPaper00058886:anp-1(ok608)_downregulated
      WBPaper00059027:neuron-synapses_enriched
      WBPaper00059328:mrps-5(RNAi)_downregulated_mRNA
      WBPaper00059356:BAZ-2_SET-6_interacting
      WBPaper00059605:MUT-16_interacting
      WBPaper00059664:srbc-48(ac23)_downregulated
      WBPaper00060014:set-2(tm1630)_upregulated
      WBPaper00060358:B.thuringiensis_pathogen_regulated_elt-2(RNAi)
      WBPaper00060358:B.thuringiensis_pathogen_regulated_N2
      WBPaper00060445:ikb-1(nr2027)_upregulated_L4
      WBPaper00060445:nfki-1(cer1)_upregulated_L4
      WBPaper00060459:bcat-1(RNAi)_downregulated
      WBPaper00060661:sensory-neuron_depleted
      WBPaper00060683:hlh-11(ko1)_downregulated
      WBPaper00060811:L1_vs_adult_downregulated_neural
      WBPaper00060886:spr-5(by101);met-2(n4256)_upregulated
      WBPaper00060909:atfs-1(cmh15)_upregulated
      WBPaper00061007:S.aquatilis_downregulated
      WBPaper00061340:ABarpaaa_lineage
      WBPaper00061340:ADA_ADE_grandparent
      WBPaper00061340:Ciliated_non_amphid_neuron
      WBPaper00061340:I2_grandparent
      WBPaper00061340:Neuroblast_ALM_BDU
      WBPaper00061340:Neuroblast_ASJ_AUA
      WBPaper00061340:Neuroblast_IL1_IL2
      WBPaper00061340:Neuroblast_PVC_LUA
      WBPaper00061340:Parent_of_hyp3_ILsoDx
      WBPaper00061340:RIC_parent
      WBPaper00061439:unc-30(ok613)_downregulated
      WBPaper00061527:let-99_22239-such-1
      WBPaper00061699:daf-18(ok480)_upregulated
      WBPaper00061818:AFD_enriched_protein
      WBPaper00061818:ELKS-1_interacting
      WBPaper00062056:lin-36(we36)_upregulated
      WBPaper00062123:DEPS-1_interacting
      WBPaper00062123:GLH-1_interacting
      WBPaper00062159:hda-2(ok1479)_downregulated
      WBPaper00062325:muscle_depleted_coding-RNA
      WBPaper00062456:doxycycline_downregulated_CB4856_protein
      WBPaper00062520:qui-1(db104)_downregulated
      WBPaper00062590:Aging_upregulated_neuron
      WBPaper00062669:extracellular-vesicle_protein
      WBPaper00064005:starvation_downregulated_aptf-1(gk794)_mRNA
      WBPaper00064005:starvation_downregulated_aptf-1(gk794)_protein
      WBPaper00064071:NHR-49_interacting
      WBPaper00064088:Day-1-adult_vs_L4_downregulated_daf-16(mu86);glp-1(e2141)
      WBPaper00064088:Day-1-adult_vs_L4_downregulated_glp-1(e2141)
      WBPaper00064088:Day-1-adult_vs_L4_upregulated_fem-3(q20)
      WBPaper00064088:Day-3-adult_vs_L4_downregulated_daf-16(mu86);glp-1(e2141)
      WBPaper00064088:Day-3-adult_vs_L4_downregulated_glp-1(e2141)
      WBPaper00064088:Day-3-adult_vs_L4_upregulated_fem-3(q20)
      WBPaper00064107:lin-35(n745)_upregulated
      WBPaper00064163:ZNFX-1_interacting_embryo
      WBPaper00064229:B.thuringiensis-Cry5Ba_downregulated
      WBPaper00064716:paraquat_upregulated
      WBPaper00064871:hypoxia_upregulated_F1
      WBPaper00065096:25C_vs_20C_upregulated
      WBPaper00065096:Day10_vs_Day1_upregulated
      WBPaper00065225:nhr-42(tm1375)_upregulated_S.aureus-infected
      WBPaper00065258:anchor-cell_depleted
      WBPaper00065373:Cisplatin_upregulated_WT
      WBPaper00065373:sek-1(km4)_upregulated_cisplatin
      WBPaper00065373:sek-1(km4)_upregulated_Ref
      WBPaper00065975:P-body_vs_oocyte_depleted
      WBPaper00065975:P-body_vs_WholeAnimal_depleted
      WBPaper00065995:M.humicola-extract_downregulated_old-1(ok1273)
      WBPaper00066038:mip-1(how5)_upregulated
      WBPaper00066110:tetraploid_vs_diploid_downregulated
      WBPaper00066146:germline-inx-14(RNAi)_downregulated_PA14
      cgc4489_group_25
      WBPaper00025032:cluster_7
      WBPaper00025141:N2_Expressed_Genes
      WBPaper00031003:24hr_muscle_depleted
      WBPaper00031003:total_muscle_depleted
      WBPaper00031060:2-deoxy-D-glucose_downregulated
      WBPaper00031252:AIN-1_IP_enriched
      WBPaper00031252:AIN-2_IP_enriched
      WBPaper00035084:embryo_enriched_AIN-2_IP
      WBPaper00035084:L1_enriched_AIN-2_IP
      WBPaper00035084:L2_enriched_AIN-2_IP
      WBPaper00035084:L3_enriched_AIN-2_IP
      WBPaper00035084:L4_enriched_AIN-2_IP
      WBPaper00035905:FBF-1_Associated
      WBPaper00036123:Atrazine_regulated
      WBPaper00036286:Pattern_B
      WBPaper00037901:GLD-1_mRNA_targets
      WBPaper00039866:ClassComp_daf-19_upregulated
      WBPaper00040426:CYD-1_CDK-4_upregulated
      WBPaper00040426:CYE-1_CDK-2AF_upregulated
      WBPaper00040821:Au-NP_regulated
      WBPaper00040823:alg-1(gk214)_downregulated
      WBPaper00040963:TA300_down
      WBPaper00041002:HF_3d_2.0mM_Down
      WBPaper00041002:HF_11d_2.0mM_Up
      WBPaper00041606:CE_B.thuringiensis-DB27_regulated
      WBPaper00041606:CE_S.marcescens_regulated
      WBPaper00041606:CE_X.nematophila_regulated
      WBPaper00041939:control_vs_EtBr-exposed_51h
      WBPaper00041939:UVC-EtBr-exposed_vs_EtBr-exposed_51h
      WBPaper00042274:tbx-2(bx59)_downregulated
      WBPaper00045263:0.1mM-paraquat_upregulated
      WBPaper00047070:N2_starvation_downregulated
      WBPaper00048637:lin-35(n745)_starvation_upregulated
      WBPaper00053236:Starvation_regulated_GR1307
      WBPaper00053236:Starvation_regulated_N2
      WBPaper00053550:daf-19(m86)_upregulated_3-fold-embryo
      WBPaper00055435:AuNPs_downregulated
      WBPaper00056330:mrps-5(RNAi)_downregulated
      [cgc6390]:Cluster_F
      [cgc6390]:intrinsic
    Interaction (72)
  Map_info: Map: V Position: 0.10906 Error: 0.000539
    Positive: Positive_clone: ZK1055 Inferred_automatically: From CDS info
            From sequence, transcript, pseudogene data
    Pseudo_map_position
  Reference (31)
  Remark: Sequence connection from [Moore LL, Roth MB]
    Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. CGC_data_submission
  Method: Gene