WormBase Tree Display for Gene: WBGene00000412

WBGene00000412 Evidence: Accession_evidence: EMBL AF301606
  SMap: S_parent: Sequence: F35E8
  Identity: Version: 1
    Name: CGC_name: cdr-1 Person_evidence: WBPerson184
      Sequence_name: F35E8.11
      Molecular_name: F35E8.11
        F35E8.11.1
        CE15961
      Other_name: CELE_F35E8.11 Accession_evidence: NDB BX284605
      Public_name: cdr-1
    DB_info: Database: AceView gene 5Q403
        WormQTL gene WBGene00000412
        WormFlux gene WBGene00000412
        NDB locus_tag CELE_F35E8.11
        Panther gene CAEEL|WormBase=WBGene00000412|UniProtKB=G5EE89
          family PTHR12289
        NCBI gene 180064
        RefSeq protein NM_074585.9
        TREEFAM TREEFAM_ID TF314915
        TrEMBL UniProtAcc G5EE89
        UniProt_GCRP UniProtAcc G5EE89
    Species: Caenorhabditis elegans
    History: Version_change: 1 07 Apr 2004 11:29:20 WBPerson1971 Event: Imported: Initial conversion from geneace
    Status: Live
  Gene_info: Biotype: SO:0001217
    Gene_class: cdr
    Allele (84)
    Strain: WBStrain00022235
      WBStrain00033925
      WBStrain00007568
      WBStrain00002104
      WBStrain00033171
    RNASeq_FPKM (74)
    GO_annotation: 00015646
      00015647
      00015648
      00015649
      00015650
      00015651
      00015652
    Ortholog (63)
    Paralog (12)
    Structured_description: Concise_description: cdr-1 encodes a member of the cadmium-inducible lysosomal family that affects susceptibility to cadmium toxicity; expressed in intestinal cells. Paper_evidence: WBPaper00005560
          Curator_confirmed: WBPerson48
          Date_last_updated: 17 Jun 2004 00:00:00
      Automated_description: Involved in stress response to cadmium ion. Located in lysosome. Expressed in intestinal cell and intestine. Paper_evidence: WBPaper00065943
          Curator_confirmed: WBPerson324
            WBPerson37462
          Inferred_automatically: This description was generated automatically by a script based on data from the WS291 version of WormBase
          Date_last_updated: 29 Nov 2023 00:00:00
  Molecular_info: Corresponding_CDS: F35E8.11
    Corresponding_transcript: F35E8.11.1
    Other_sequence: AF301606
    Associated_feature: WBsf647611
      WBsf233056
  Experimental_info: RNAi_result: WBRNAi00031789 Inferred_automatically: RNAi_primary
      WBRNAi00103330 Inferred_automatically: RNAi_primary
      WBRNAi00070115 Inferred_automatically: RNAi_primary
      WBRNAi00095210 Inferred_automatically: RNAi_primary
      WBRNAi00014337 Inferred_automatically: RNAi_primary
      WBRNAi00095101 Inferred_automatically: RNAi_primary
      WBRNAi00046357 Inferred_automatically: RNAi_primary
      WBRNAi00095211 Inferred_automatically: RNAi_primary
    Expr_pattern: Chronogram313
      Chronogram363
      Expr2331
      Expr2345
      Expr14913
      Expr1016514
      Expr1150238
      Expr2009821
      Expr2028062
    Drives_construct: WBCnstr00001011
      WBCnstr00001076
      WBCnstr00002881
      WBCnstr00037561
      WBCnstr00041581
    Construct_product: WBCnstr00037561
    Microarray_results (17)
    Expression_cluster: WBPaper00029359_1217
      WBPaper00029359_1280
      WBPaper00029359_1353
      WBPaper00029359_1444
      WBPaper00029359_1504
      WBPaper00029359_1548
      WBPaper00029359_1604
      WBPaper00032479:CB4856vsN2_LifeStageProfile_Variation
      WBPaper00037950:all-neurons_L1-larva_expressed
      WBPaper00037950:AVE-neuron_L1-larva_expressed
      WBPaper00037950:bodywall-muscle_L1-larva_expressed
      WBPaper00037950:coelomocytes_L1-larva_expressed
      WBPaper00037950:dopaminergic-neurons_L1-larva_expressed
      WBPaper00037950:germline-precursors_blastula-embryo_expressed
      WBPaper00037950:hypodermis_L1-larva_expressed
      WBPaper00037950:intestine_L1-larva_expressed
      WBPaper00037950:intestine_L2-larva_expressed
      WBPaper00037950:intestine_larva_enriched
      WBPaper00037950:intestine_larva_SelectivelyEnriched
      WBPaper00037950:pharyngeal-muscle_L1-larva_expressed
      WBPaper00038438:E.faecalis_24hr_upregulated_RNAseq
      WBPaper00038438:E.faecalis_24hr_upregulated_TilingArray
      WBPaper00038438:P.lumniescens_24hr_upregulated_RNAseq
      WBPaper00038438:P.lumniescens_24hr_upregulated_TilingArray
      WBPaper00038438:S.marcescens_24hr_upregulated_RNAseq
      WBPaper00038438:S.marcescens_24hr_upregulated_TilingArray
      WBPaper00041954:ethanol_upregulated
      WBPaper00042194:Tryptophan_upregulated
      WBPaper00042215:wdr-23(tm1817)_upregulated
      WBPaper00044260:1-methylnicotinamide_upregulated
      WBPaper00044736:flat_dev_expression
      WBPaper00045316:prg-1_upregulated_L4
      WBPaper00045420:fertilization_downregulated_transcript
      WBPaper00045918:96h_infection_recovery_upregulated
      WBPaper00045918:120h_infection_recovery_upregulated
      WBPaper00046497:B.thuringiensis_0.1mix_downregulated_6h
      WBPaper00046497:B.thuringiensis_0.1mix_downregulated_12h
      WBPaper00046497:B.thuringiensis_0.5mix_downregulated_6h
      WBPaper00046497:B.thuringiensis_0.5mix_downregulated_12h
      WBPaper00048926:miaserin_upregulated_adult-day3
      WBPaper00049217:DAF-16_downregulated
      WBPaper00049266:NaAsO2-Stress_regulated_N2
      WBPaper00049334:CE_intestine_enriched
      WBPaper00049377:MWCNT_upregulated
      WBPaper00049498:npr-1(ur89)_regulated_7
      WBPaper00049545:jmjd-3.1(+)_upregulated
      WBPaper00049545:rgef-1p-jmjd-1.2(+)_upregulated
      WBPaper00049545:sur-5p-jmjd-1.2(+)_upregulated
      WBPaper00049736:daf-2(e1370)_downregulated_15deg-then-25deg(12hr)
      WBPaper00049942:hsf-1(RNAi)_downregulated
      WBPaper00050096:P.aeruginosa_upregulated
      WBPaper00050344:ASER-neuron_enriched
      WBPaper00050344:PLM-neuron_enriched
      WBPaper00050370:dpy-21(e428)_L3_upregulated
      WBPaper00050488:adult_vs_dauer_regulated_N2_20C
      WBPaper00050488:mir-34(gk437)_vs_mir-34(OverExpression)_regulated_dauer_20C
      WBPaper00050488:N2_vs_mir-34(gk437)_regulated_dauer_20C
      WBPaper00050561:indole_0.1mM-indole_upregulated
      WBPaper00050561:indole_10-fold_upregulated
      WBPaper00050859:upregulated_P-granule(-)GFP(+)_vs_control_day2-adult
      WBPaper00050990:intestine_enriched
      WBPaper00050990:intestine_expressed
      WBPaper00051021:4-bromodiphenyl-ether_upregulated
      WBPaper00051039:ash-2(RNAi)_regulated_intestine
      WBPaper00051039:intestine_enriched
      WBPaper00051404:alg-1(gk214)_upregulated
      WBPaper00052856:Cadmium_regulated
      WBPaper00053295:lin-22(ot269)_upregulated
      WBPaper00053302:stavudine_24h_regulated
      WBPaper00053302:zidovudine_72h_regulated
      WBPaper00053810:nuo-6(qm200)_upregulated
      WBPaper00053909:N2_vs_CB4856_upregulated
      WBPaper00055060:flr-1(RNAi)_upregulated
      WBPaper00055354:Psora-Allantoin_upregulated
      WBPaper00055354:Psora_upregulated
      WBPaper00055354:Rapamycin-Psora-Allantoin_upregulated
      WBPaper00055354:Rapamycin-Psora_upregulated
      WBPaper00055354:Rapamycin-Rifampicin-Psora_upregulated
      WBPaper00055354:Rifampicin-Psora_upregulated
      WBPaper00055386:daf-2(e1370)_downregulated
      WBPaper00055626:pry-1(mu38)_downregulated
      WBPaper00055862:antimycin_damt-1(gk961032)_regulated
      WBPaper00055941:nuo-6(qm200)_upregulated
      WBPaper00056090:E.faecalis_upregulated_hpx-2(dg047)
      WBPaper00056090:E.faecalis_upregulated_N2
      WBPaper00056169:rrf-3(pk1426)_downregulated_L2
      WBPaper00056218:daf-16(mu86)_downregulated_Day3
      WBPaper00056218:daf-16(mu86)_downregulated_Day7
      WBPaper00056275:P.aeruginosa_upregulated
      WBPaper00056290:mdt-15(mg584)_upregulated
      WBPaper00056550:ceh-60(ok1485)_upregulated_AdultDay1
      WBPaper00057041:unc-70(cas983)_downregulated
      WBPaper00057068:Cadmium_upregulated
      WBPaper00057265:metaformin_upregulated_OP50
      WBPaper00058599:benzimidazoles_upregulated
      WBPaper00058711:skn-1(lax188)_upregulated
      WBPaper00058725:sftb-1(cer39)_upregulated
      WBPaper00058948:PA14_downregulated
      WBPaper00059027:neuron-synapses_depleted
      WBPaper00059117:B.subtilis_upregulated
      WBPaper00059194:klf-1(RNAi)_regulated
      WBPaper00059253:stearic-acid_downregulated
      WBPaper00059253:sucrose_downregulated
      WBPaper00059253:sucrose_stearic-acid_downregulated
      WBPaper00059604:fluvastatin_downregulated_dlk-1(km12)
      WBPaper00059604:fluvastatin_downregulated_N2
      WBPaper00059664:srbc-48(ac23)_upregulated
      WBPaper00059754:C.neoformans_H99_upregulated
      WBPaper00059754:E.faecalis_OG1RF_upregulated
      WBPaper00059754:P.aeruginosa_PA14_upregulated
      WBPaper00059824:rnp-6(dh1127)_regulated_OP50
      WBPaper00059839:S.maltophilia_regulated
      WBPaper00059895:wounding_upregulated
      WBPaper00060358:B.thuringiensis_non-pathogen_regulated_elt-2(RNAi)
      WBPaper00060358:B.thuringiensis_pathogen_regulated_elt-2(RNAi)
      WBPaper00060399:CoCl2_6hr_upregulated_N2
      WBPaper00060445:ikb-1(nr2027)_upregulated_L1
      WBPaper00060661:sensory-neuron_depleted
      WBPaper00060811:L1_vs_adult_downregulated_neural
      WBPaper00060909:atfs-1(cmh15)_downregulated
      WBPaper00060911:prx-5(RNAi)_upregulated_mRNA
      WBPaper00061007:HB115_upregulated
      WBPaper00061007:S.aquatilis_upregulated
      WBPaper00061081:E.faecalis_upregulated_N2
      WBPaper00061081:E.faecalis_upregulated_skpo-1(ok1640)
      WBPaper00061341:28C_48h_downregulated
      WBPaper00061527:F55G11.8-dod-17
      WBPaper00061590:CGP37157_upregulated
      WBPaper00062078:NMR-HspB1_regulated
      WBPaper00062146:MOG-7-degron_2h_regulated
      WBPaper00062159:hda-2(ok1479)_upregulated
      WBPaper00062193:skn-1(RNAi)_upregulated
      WBPaper00062325:muscle_depleted_coding-RNA
      WBPaper00062446:nhr-8(hd117)_upregulated
      WBPaper00062669:extracellular-vesicle_protein
      WBPaper00064088:Day-1-adult_vs_L4_upregulated_daf-16(mu86);glp-1(e2141)
      WBPaper00064088:Day-1-adult_vs_L4_upregulated_fem-3(q20)
      WBPaper00064088:Day-1-adult_vs_L4_upregulated_glp-1(e2141)
      WBPaper00064088:Day-3-adult_vs_L4_upregulated_daf-16(mu86);glp-1(e2141)
      WBPaper00064088:Day-3-adult_vs_L4_upregulated_fem-3(q20)
      WBPaper00064088:Day-3-adult_vs_L4_upregulated_glp-1(e2141)
      WBPaper00064107:lin-35(n745)_upregulated
      WBPaper00064509:static-magnetic-field_upregulated
      WBPaper00064539:nhr-114(gk849)_upregulated
      WBPaper00064871:P.fluorescens_upregulated_AWA
      WBPaper00064871:PA14_upregulated_AWA
      WBPaper00065029:cadmium_upregulated
      WBPaper00065158:25C_vs_15C_downregulated_WholeAnimal
      WBPaper00065288:mdt-15(tm2182)_downregulated
      WBPaper00065392:Lb.gasseri_upregulated
      WBPaper00065392:Lb.reuteri_upregulated
      WBPaper00065392:Lb.rhamnosus_upregulated
      WBPaper00065392:P.pentosaceus_upregulated
      WBPaper00065749:Heat-Shock_downregulated_endu-2(tm4977)
      WBPaper00065841:34_0
      WBPaper00065975:P-body_vs_WholeAnimal_depleted
      WBPaper00065993:glp-1(e2141)_upregulated
      WBPaper00066204:CdCl2_upregulated_mRNA
      WBPaper00066232:ash-2(RNAi)_upregulated_WT
      WBPaper00066232:hsf-1(RNAi)_downregulated_ash-2
      cgc4386_cluster_6_5
      WBPaper00025141:N2_Expressed_Genes
      WBPaper00025141:unc-4::GFP_Expressed_Genes
      WBPaper00026952:class_E
      WBPaper00027111:eri-1(mg366)_downregulated
      WBPaper00028789:PA14_vs_OP50_upregulated_4hr
      WBPaper00028789:PA14_vs_OP50_upregulated_8hr
      WBPaper00030985:Photorhabdus_luminescens_upregulated
      WBPaper00032948:FedUp
      WBPaper00034739:TreatmentAffectedGenes
      WBPaper00035479:daf-16(RNAi)_upregulated
      WBPaper00035588:alg-1(-)_upregulated
      WBPaper00036123:Atrazine_regulated
      WBPaper00036123:Cadmium_regulated
      WBPaper00036286:Pattern_D
      WBPaper00037113:Chlorpyrifos_Diazinon_16C_regulated
      WBPaper00037113:CPF_16C_up-regulated
      WBPaper00037113:DZN_16C_up-regulated
      WBPaper00038231:Cry5B_1.5-fold_downregulated
      WBPaper00040184:hcf-1down_sir-2.1down_daf-2down
      WBPaper00041002:HF_3d_2.0mM_Up
      WBPaper00041211:RPW-24_Up
      WBPaper00041370:spg-7(RNAi)_upregulated
      WBPaper00041606:CE_X.nematophila_regulated
      WBPaper00041939:control_vs_EtBr-exposed_48h
      WBPaper00041939:control_vs_EtBr-exposed_51h
      WBPaper00041939:control_vs_UVC-EtBr-exposed_48h
      WBPaper00041939:control_vs_UVC-EtBr-exposed_51h
      WBPaper00041939:EtBr-exposed_vs_UVC-exposed_3h
      WBPaper00041939:EtBr-exposed_vs_UVC-exposed_51h
      WBPaper00041939:UVC-EtBr-exposed_vs_UVC-exposed_51h
      WBPaper00042128:gei-8(ok1671)_upregulated
      WBPaper00044091:Bpseudomallei_induced_8h
      WBPaper00045673:colistin_upregulated
      WBPaper00047070:N2_UV_upregulated
      WBPaper00053236:Starvation_regulated_GR1307
      WBPaper00053236:Starvation_regulated_N2
      WBPaper00053688:E.faecalis_downregulated
      WBPaper00055899:2,4-Dinitroanisole_regulated
      WBPaper00055899:nitrotriazolone_regulated
    Interaction: WBInteraction000276442
      WBInteraction000501576
      WBInteraction000571028
      WBInteraction000585672
    WBProcess: WBbiopr:00000096
  Map_info: Map: V Position: 9.14051 Error: 0.016434
    Positive: Positive_clone: F35E8 Inferred_automatically: From CDS info
            From sequence, transcript, pseudogene data
    Mapping_data: Multi_point: 4905
        5592
    Pseudo_map_position
  Reference (18)
  Remark: Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. CGC_data_submission
  Method: Gene