WormBase Tree Display for Gene: WBGene00000179

WBGene00000179 Evidence: Person_evidence: WBPerson548
  SMap: S_parent: Sequence: ZK525
  Identity: Version: 1
    Name: CGC_name: aqp-11 Person_evidence: WBPerson300
      Sequence_name: ZK525.2
      Molecular_name: ZK525.2
        ZK525.2.1
        CE33909
      Other_name: CELE_ZK525.2 Accession_evidence: NDB BX284603
      Public_name: aqp-11
    DB_info: Database: AceView gene 3O765
        WormQTL gene WBGene00000179
        WormFlux gene WBGene00000179
        NDB locus_tag CELE_ZK525.2
        Panther gene CAEEL|WormBase=WBGene00000179|UniProtKB=O46024
          family PTHR21191
        NCBI gene 191343
        RefSeq protein NM_067420.7
        TREEFAM TREEFAM_ID TF320251
        TrEMBL UniProtAcc O46024
        UniProt_GCRP UniProtAcc O46024
    Species: Caenorhabditis elegans
    History: Version_change: 1 07 Apr 2004 11:29:20 WBPerson1971 Event: Imported: Initial conversion from geneace
    Status: Live
  Gene_info: Biotype: SO:0001217
    Gene_class: aqp
    Allele (23)
    Strain: WBStrain00033245
    RNASeq_FPKM (74)
    GO_annotation: 00035829
      00035830
      00035831
      00035832
      00035833
      00035834
    Ortholog (35)
    Paralog: WBGene00000177 Caenorhabditis elegans From_analysis: TreeFam
            Panther
            WormBase-Compara
      WBGene00000178 Caenorhabditis elegans From_analysis: Panther
            WormBase-Compara
    Structured_description: Concise_description: aqp-11 encodes a putative aquaporin with no function in mass RNAi assays, perhaps reflecting genetic redundancy with its paralogs AQP-9 and AQP-10; AQP-11 is orthologous to Drosophila CG12251 and human AQP11 (OMIM:609914), AQP12A (OMIM:609789), and AQP12B. Paper_evidence: WBPaper00029039
          Curator_confirmed: WBPerson567
          Date_last_updated: 12 Aug 2007 00:00:00
      Automated_description: Predicted to enable channel activity. Predicted to be involved in transmembrane transport. Predicted to be located in cytoplasm. Is an ortholog of human AQP11 (aquaporin 11); AQP12A (aquaporin 12A); and AQP12B (aquaporin 12B). Paper_evidence: WBPaper00065943
          Curator_confirmed: WBPerson324
            WBPerson37462
          Inferred_automatically: This description was generated automatically by a script based on data from the WS291 version of WormBase
          Date_last_updated: 29 Nov 2023 00:00:00
  Molecular_info (5)
  Experimental_info: RNAi_result: WBRNAi00022047 Inferred_automatically: RNAi_primary
      WBRNAi00006366 Inferred_automatically: RNAi_primary
      WBRNAi00059496 Inferred_automatically: RNAi_primary
      WBRNAi00038327 Inferred_automatically: RNAi_primary
    Expr_pattern: Expr1028951
      Expr1030103
      Expr1162911
      Expr2009377
      Expr2027613
    Drives_construct: WBCnstr00037683
    Construct_product: WBCnstr00037683
    Microarray_results (20)
    Expression_cluster: WBPaper00027022:cnb-1(jh103)_downregulated
      WBPaper00031040:TGF-beta_adult_upregulated
      WBPaper00032425:up_in_zfp-1
      WBPaper00032528:L3_enriched
      WBPaper00037950:BAG-neuron_blastula-embryo_expressed
      WBPaper00037950:bodywall-muscle_L1-larva_expressed
      WBPaper00037950:bodywall-muscle_L2-larva_expressed
      WBPaper00037950:CEP-sheath-cells_Day1-adult_expressed
      WBPaper00037950:coelomocytes_embryo_enriched
      WBPaper00037950:coelomocytes_L1-larva_expressed
      WBPaper00037950:excretory-cell_L2-larva_expressed
      WBPaper00037950:hypodermis_L3-L4-larva_expressed
      WBPaper00037950:intestine_L1-larva_expressed
      WBPaper00037950:intestine_L2-larva_expressed
      WBPaper00037950:intestine_larva_enriched
      WBPaper00037950:pharyngeal-muscle_L1-larva_expressed
      WBPaper00037950:PVD-OLL-neurons_L3-L4-larva_expressed
      WBPaper00038438:S.marcescens_24hr_upregulated_RNAseq
      WBPaper00040412:germline-regulated_daf-12_target
      WBPaper00042215:wdr-23(tm1817)_upregulated
      WBPaper00044736:flat_dev_expression
      WBPaper00045390:tunicamycin_upregulated
      WBPaper00045521:Spermatogenic
      WBPaper00045774:clk-1_downregulated
      WBPaper00046497:B.thuringiensis_0.1mix_downregulated_6h
      WBPaper00046497:B.thuringiensis_0.1mix_downregulated_12h
      WBPaper00046497:B.thuringiensis_0.5mix_downregulated_6h
      WBPaper00046497:B.thuringiensis_0.5mix_downregulated_12h
      WBPaper00046509:htz-1(ok3099)_downregulated
      WBPaper00046509:lin-35(n745)_downregulated
      WBPaper00046795:starvation_downregulated
      WBPaper00048988:neuron_expressed
      WBPaper00049498:npr-1(ur89)_regulated_3
      WBPaper00049545:cco-1(RNAi)_downregulated
      WBPaper00049732:blmp-1(tm548)_vs_N2_downregulated
      WBPaper00050332:skn-1(RNAi)_downregulated
      WBPaper00050488:20C_vs_25C_regulated_N2_adult
      WBPaper00050488:adult_vs_dauer_regulated_N2_20C
      WBPaper00050488:mir-34(gk437)_vs_mir-34(OverExpression)_regulated_dauer_20C
      WBPaper00050488:N2_vs_mir-34(gk437)_regulated_dauer_20C
      WBPaper00050686:glp-1(e2141)_upregulated
      WBPaper00050726:OsmoticStress_regulated_Food
      WBPaper00050726:starvation_regulated_LowSalt
      WBPaper00050859:upregulated_P-granule(-)GFP(+)_vs_control_day2-adult
      WBPaper00050859:upregulated_P-granule(-)GFP(-)_vs_control_day1-adult
      WBPaper00050859:upregulated_P-granule(-)GFP(-)_vs_control_day2-adult
      WBPaper00050859:upregulated_pgl-1(ct131)_vs_control_day1-adult
      WBPaper00050990:intestine_enriched
      WBPaper00050990:intestine_expressed
      WBPaper00051039:intestine_enriched
      WBPaper00051311:VGLN-1-interacting
      WBPaper00053184:sma-2(rax5)_downregulated
      WBPaper00053302:stavudine_24h_regulated
      WBPaper00053302:zidovudine_72h_regulated
      WBPaper00053388:dauer_regulated_Cluster6
      WBPaper00053599:mitosis_vs_meiosis_downregulated
      WBPaper00053599:oocyte_vs_mitosis_downregulated
      WBPaper00053713:Starvation-induced_postdauer_vs_control_upregulated
      WBPaper00053810:daf-2(e1370)_downregulated
      WBPaper00053814:15C_downregulated_PY79
      WBPaper00055354:Rapamycin-Allantoin_downregulated
      WBPaper00055827:daf-2(e1370)_downregulated
      WBPaper00056284:ints-4(RNAi)_downregulated
      WBPaper00056443:sek-1(km4)_upregulated
      WBPaper00056826:SGP_biased
      WBPaper00057041:unc-70(cas983)_upregulated
      WBPaper00058598:sin-3(tm1276)_downregulated
      WBPaper00058691:cfp-1(tm6369)_downregulated
      WBPaper00058691:sin-3(tm1276)_downregulated
      WBPaper00058711:skn-1(lax188)_upregulated
      WBPaper00059328:mrps-5(RNAi)_upregulated_mRNA
      WBPaper00059471:EGL-43_interacting
      WBPaper00059664:srbc-48(ac23)_upregulated
      WBPaper00059824:rnp-6(dh1127)_regulated_OP50
      WBPaper00059824:rnp-6(dh1127)_regulated_S.aureus
      WBPaper00059987:Wounding_downregulated
      WBPaper00060084:cco-1(RNAi)_downregulated_N2
      WBPaper00060358:B.thuringiensis_pathogen_regulated_elt-2(RNAi)
      WBPaper00060358:B.thuringiensis_pathogen_regulated_N2
      WBPaper00060811:L1_vs_adult_downregulated_neural
      WBPaper00060909:atfs-1(cmh15)_downregulated
      WBPaper00061203:let-418(n3536)_upregulated
      WBPaper00061203:sin-3(tm1276)_upregulated
      WBPaper00061203:spr-1(ok2144)_upregulated
      WBPaper00061341:28C_48h_downregulated
      WBPaper00061439:unc-30(ok613)_upregulated
      WBPaper00061479:hda-1(ne4752)_upregulated
      WBPaper00061527:dhs-28_22199-acs-14
      WBPaper00062325:muscle_enriched_coding-RNA
      WBPaper00062354:H.zoospora_6h_regulated
      WBPaper00062590:Aging_downregulated_hypodermis
      WBPaper00064005:starvation_downregulated_N2_mRNA
      WBPaper00064071:NHR-49_interacting
      WBPaper00064088:Day-1-adult_vs_L4_upregulated_daf-16(mu86);glp-1(e2141)
      WBPaper00064315:mes-4(bn73)_upregulated_EGCs
      WBPaper00064716:paraquat_downregulated
      WBPaper00064933:bcf-1(ylf1)_downregulated_transcript
      WBPaper00065086:JU1400_N.ausubeli_regulated
      WBPaper00065086:JU1400_N.ferruginous_regulated
      WBPaper00065096:Day10_vs_Day1_downregulated
      WBPaper00065120:body-muscle-transcriptome
      WBPaper00065835:Day11_vs_Day1_downregulated
      WBPaper00065841:37_0
      WBPaper00065975:P-body_vs_WholeAnimal_depleted
      WBPaper00065993:glp-1(e2141)_upregulated
      WBPaper00066085:sin-3(tm1276)_upregulated
      cgc4386_cluster_3_3
      cgc4489_group_3
      WBPaper00005124:cholesterol_10-9M_regulated
      WBPaper00025032:cluster_24
      WBPaper00025099:MA_specific
      WBPaper00025141:N2_Expressed_Genes
      WBPaper00026980:intestine_enriched
      WBPaper00031003:0hr_muscle_enriched
      WBPaper00031003:24hr_muscle_enriched
      WBPaper00031003:hlh_1_enriched
      WBPaper00031003:total_muscle_enriched
      WBPaper00032062:age_regulated_genes
      WBPaper00032948:FedUp
      WBPaper00035873:dpy-10_regulated
      WBPaper00036286:Pattern_C
      WBPaper00040184:hcf-1down_sir-2.1down_daf-2down
      WBPaper00040963:TA300_up
      WBPaper00041002:HQ_3d_0.2mM_Up
      WBPaper00041606:CE_X.nematophila_regulated
      WBPaper00041906:I-3690_vs_OP50_3d
      WBPaper00041939:control_vs_EtBr-exposed_24h
      WBPaper00041939:control_vs_EtBr-exposed_48h
      WBPaper00041939:control_vs_UVC-EtBr-exposed_24h
      WBPaper00041939:EtBr-exposed_vs_UVC-exposed_48h
      WBPaper00041939:UVC-EtBr-exposed_vs_UVC-exposed_48h
      WBPaper00044091:Bpseudomallei_induced_8h
      WBPaper00047070:N2_starvation_downregulated
      WBPaper00053236:Starvation_regulated_GR1307
      WBPaper00053236:Starvation_regulated_N2
      WBPaper00055899:nitrotriazolone_regulated
      [cgc5767]:cluster_2
      [cgc5767]:expression_class_E
      [cgc5767]:expression_class_E_pi(53_min)
      [cgc5767]:expression_class_SE
      [cgc5767]:expression_class_SE_pi(53_min)
      [cgc6390]:Cluster_C
    Interaction (49)
  Map_info: Map: III Position: 21.3482 Error: 0.003133
    Positive: Positive_clone: ZK525 Inferred_automatically: From sequence, transcript, pseudogene data
    Pseudo_map_position
  Reference: WBPaper00010068
    WBPaper00019560
    WBPaper00027012
  Remark: Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. CGC_data_submission
  Method: Gene