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WormBase Tree Display for Gene: WBGene00016173

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Name Class

WBGene00016173SMapS_parentSequenceC27H5
IdentityVersion2
NameCGC_namefust-1Person_evidenceWBPerson1352
Sequence_nameC27H5.3
Molecular_nameC27H5.3a
C27H5.3a.1
CE27099
C27H5.3b
CE51847
C27H5.3b.1
C27H5.3b.2
Other_nameCELE_C27H5.3Accession_evidenceNDBBX284602
Public_namefust-1
DB_infoDatabaseAceViewgene2H445
WormQTLgeneWBGene00016173
WormFluxgeneWBGene00016173
NDBlocus_tagCELE_C27H5.3
PanthergeneCAEEL|WormBase=WBGene00016173|UniProtKB=Q18265
familyPTHR23238
NCBIgene174175
RefSeqproteinNM_063082.7
NM_001381492.1
TrEMBLUniProtAccQ18265
A0A1N7SYQ6
UniProt_GCRPUniProtAccQ18265
OMIMgene133450
137070
601574
SpeciesCaenorhabditis elegans
HistoryVersion_change128 May 2004 13:30:57WBPerson1971EventImportedInitial conversion from CDS class of stlace from WS125
203 Aug 2010 10:05:58WBPerson2970Name_changeCGC_namefust-1
StatusLive
Gene_infoBiotypeSO:0001217
Gene_classfust
Allele (42)
StrainWBStrain00001567
WBStrain00047288
WBStrain00047287
WBStrain00047289
WBStrain00050865
RNASeq_FPKM (74)
GO_annotation (11)
Ortholog (47)
Structured_descriptionAutomated_descriptionPredicted to enable RNA binding activity and transcription coregulator activity. Predicted to be involved in regulation of DNA-templated transcription. Predicted to be located in nucleus. Expressed in gonad; head; intestinal cell; neurons; and tail. Human ortholog(s) of this gene implicated in amyotrophic lateral sclerosis type 6; connective tissue cancer (multiple); and essential tremor 4. Is an ortholog of human FUS (FUS RNA binding protein).Paper_evidenceWBPaper00065943
Curator_confirmedWBPerson324
WBPerson37462
Inferred_automaticallyThis description was generated automatically by a script based on data from the WS291 version of WormBase
Date_last_updated29 Nov 2023 00:00:00
Disease_infoPotential_modelDOID:1289Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:4010)
DOID:0111431Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:4010)
DOID:0060198Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:4010)
DOID:4549Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:11547)
DOID:1115Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:4010)
DOID:332Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:4010)
DOID:3382Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:4010)
DOID:3371Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:11547)
DOID:3369Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:3508)
Molecular_infoCorresponding_CDSC27H5.3a
C27H5.3b
Corresponding_transcriptC27H5.3a.1
C27H5.3b.1
C27H5.3b.2
Other_sequence (37)
Associated_featureWBsf644354
WBsf988367
WBsf221563
Experimental_infoRNAi_resultWBRNAi00090580Inferred_automaticallyRNAi_primary
WBRNAi00011275Inferred_automaticallyRNAi_primary
WBRNAi00083277Inferred_automaticallyRNAi_primary
WBRNAi00076171Inferred_automaticallyRNAi_primary
WBRNAi00041374Inferred_automaticallyRNAi_primary
Expr_pattern (11)
Drives_constructWBCnstr00002407
WBCnstr00028273
WBCnstr00042661
WBCnstr00042662
WBCnstr00042663
Construct_productWBCnstr00028273
WBCnstr00042661
WBCnstr00042662
WBCnstr00042663
Regulate_expr_clusterWBPaper00066004:fust-1(csb21)_downregulated
WBPaper00066004:fust-1(csb21)_upregulated
Microarray_results (19)
Expression_clusterWBPaper00033065:isp-1-1(qm150)_upregulated
WBPaper00037950:A-class-motor-neurons_L2-larva_expressed
WBPaper00037950:all-neurons_L2-larva_expressed
WBPaper00037950:bodywall-muscle_L2-larva_expressed
WBPaper00037950:dopaminergic-neurons_L3-L4-larva_expressed
WBPaper00037950:pharyngeal-muscle_L1-larva_expressed
WBPaper00037950:PVD-OLL-neurons_L3-L4-larva_expressed
WBPaper00038438:Harposporium_24hr_downregulated_RNAseq
WBPaper00040221:DAF-12_target_ALF4
WBPaper00044037:eat-2_downregulated
WBPaper00044656:tatn-1(qd182)_downregulated
WBPaper00044736:flat_dev_expression
WBPaper00045420:fertilization_downregulated_transcript
WBPaper00045521:Gender_Neutral
WBPaper00045974:NSM_enriched_totalRNA_RNAseq
WBPaper00046497:B.thuringiensis_0.1mix_downregulated_6h
WBPaper00046497:B.thuringiensis_0.1mix_downregulated_12h
WBPaper00046497:B.thuringiensis_0.5mix_downregulated_6h
WBPaper00046497:B.thuringiensis_0.5mix_downregulated_12h
WBPaper00046509:htz-1(ok3099)_downregulated
WBPaper00048988:neuron_expressed
WBPaper00049545:cco-1(RNAi)_downregulated
WBPaper00049545:jmjd-3.1(+)_downregulated
WBPaper00049545:sur-5p-jmjd-1.2(+)_downregulated
WBPaper00050370:dpy-21(e428)_L3_downregulated
WBPaper00050412:cco-1(RNAi)_downregulated_N2
WBPaper00050990:GABAergic-neuron_expressed
WBPaper00050990:hypodermis_expressed
WBPaper00050990:intestine_expressed
WBPaper00050990:NMDA-neuron_expressed
WBPaper00051039:germline_enriched
WBPaper00051245:body-wall-muscle_cytoplasm_expressed
WBPaper00051245:body-wall-muscle_nucleus_expressed
WBPaper00051245:epidermis_cytoplasm_expressed
WBPaper00051245:epidermis_nucleus_expressed
WBPaper00051245:intestine_cytoplasm_expressed
WBPaper00051245:intestine_nucleus_expressed
WBPaper00051245:nucleus_specific
WBPaper00052884:emb-4(hc60)_downregulated
WBPaper00052987:UV_upregulated_xpc-1;csb-1
WBPaper00053184:sma-2(rax5)_downregulated
WBPaper00053184:sma-4(rax3)_downregulated
WBPaper00053289:DREAM-target
WBPaper00053302:alovudine_72h_regulated
WBPaper00053308:SMG-2_associated_NMD(-)_unaltered_ClassII
WBPaper00053810:isp-1(qm150)_downregulated
WBPaper00053810:nuo-6(qm200)_downregulated
WBPaper00055354:Rapamycin-Metformin_upregulated
WBPaper00055565:AVK_enriched
WBPaper00055648:germline_expressed
WBPaper00055971:nhl-2(ok818)_25C_upregulated
WBPaper00056090:E.faecalis_downregulated_hpx-2(dg047)
WBPaper00056139:soil-microbiota_downregulated
WBPaper00056293:rpl-5(0)-rpl-33(0)_downregulated
WBPaper00057288:Cold_downregulated_transcript
WBPaper00057288:iff-1(RNAi)_downregulated_transcript
WBPaper00058691:CFP-1_interacting_protein
WBPaper00058958:100mGy-irradiation-72h_upregulated
WBPaper00059356:BAZ-2_SET-6_interacting
WBPaper00059471:EGL-43_interacting
WBPaper00060100:SiNP_upregulated_mRNA
WBPaper00060358:B.thuringiensis_pathogen_regulated_N2
WBPaper00060459:bcat-1(RNAi)_downregulated
WBPaper00060811:L1_vs_adult_upregulated_neural
WBPaper00061527:dld-1-skn-1_16701
WBPaper00061527:tub-2_4713-daf-2_5288
WBPaper00062159:hda-2(ok1479)_downregulated
WBPaper00062325:muscle_enriched_coding-RNA
WBPaper00062354:H.zoospora_6h_regulated
WBPaper00064071:NHR-49_interacting
WBPaper00064080:miR-58_miRNA_interacting
WBPaper00064992:Capsaicin_downregulated
WBPaper00065120:body-muscle-transcriptome
WBPaper00065993:glp-1(e2141)_downregulated
WBPaper00066004:fust-1(csb21)_downregulated
cgc4386_cluster_6_3
cgc4489_group_8
WBPaper00025032:cluster_7
WBPaper00025032:cluster_13
WBPaper00025141:N2_Expressed_Genes
WBPaper00025141:unc-4::GFP_Expressed_Genes
WBPaper00026929:Resveratrol_regulated_daf-16
WBPaper00026929:sir-2.1_overexpression_regulated
WBPaper00026980:intestine_enriched
WBPaper00027111:rde-3(ne298)_upregulated
WBPaper00031003:0hr_muscle_depleted
WBPaper00031003:total_muscle_depleted
WBPaper00031832:slr-2_regulated
WBPaper00032165:differentially_expressed_with_age_medoid_1
WBPaper00035905:FBF-1_Associated
WBPaper00036123:Cadmium_regulated
WBPaper00036286:Pattern_G
WBPaper00037695:WC_5-day
WBPaper00041606:CE_B.thuringiensis-DB27_regulated
WBPaper00041606:CE_X.nematophila_regulated
WBPaper00041939:control_vs_EtBr-exposed_48h
WBPaper00041939:EtBr-exposed_vs_UVC-exposed_48h
WBPaper00041939:UVC-EtBr-exposed_vs_UVC-exposed_24h
WBPaper00041939:UVC-EtBr-exposed_vs_UVC-exposed_48h
WBPaper00041939:UVC-EtBr-exposed_vs_UVC-exposed_51h
WBPaper00042274:tbx-2(bx59)_downregulated
WBPaper00042331:a-SWCNTs_downregulated
WBPaper00045263:nuo-6(qm200)_downregulated
WBPaper00055435:AuNPs_downregulated
[cgc5767]:cluster_4
[cgc5767]:expression_class_E
[cgc5767]:expression_class_E_pi(23_min)
[cgc5767]:expression_class_M
[cgc5767]:expression_class_ME
Interaction (197)
Map_infoMapIIPosition0.496031Error0.000218
PositivePositive_cloneC27H5Inferred_automaticallyFrom sequence, transcript, pseudogene data
Pseudo_map_position
ReferenceWBPaper00038491
WBPaper00039140
WBPaper00043234
WBPaper00046432
WBPaper00052702
WBPaper00053121
WBPaper00053757
WBPaper00055090
WBPaper00058116
WBPaper00062110
WBPaper00063415
WBPaper00063450
WBPaper00064663
WBPaper00066004
WBPaper00066342
RemarkMap position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC.CGC_data_submission
MethodGene