Questions, Feedback & Help
Send us an email and we'll get back to you ASAP. Or you can read our Frequently Asked Questions.

WormBase Tree Display for Gene: WBGene00000800

expand all nodes | collapse all nodes | view schema

Name Class

WBGene00000800SMapS_parentSequenceY23H5A
IdentityVersion2
NameCGC_namecars-1Person_evidenceWBPerson36
WBPerson10953
Sequence_nameY23H5A.7
Molecular_nameY23H5A.7b
Y23H5A.7b.1
CE54491
Y23H5A.7c
CE49746
Y23H5A.7c.1
Other_namecrs-1
CELE_Y23H5A.7Accession_evidenceNDBBX284601
Public_namecars-1
DB_infoDatabaseAceViewgene1D192
WormQTLgeneWBGene00000800
WormFluxgeneWBGene00000800
NDBlocus_tagCELE_Y23H5A.7
PanthergeneCAEEL|WormBase=WBGene00000800|UniProtKB=O76618
familyPTHR10890
NCBIgene171821
RefSeqproteinNM_001306359.3
NM_058613.7
KEGGKEGG_id6.1.1.16
NemaPathKEGG_id6.1.1.16
TrEMBLUniProtAccA0A061ACL3
A0A8S4QD27
SpeciesCaenorhabditis elegans
HistoryVersion_change107 Apr 2004 11:29:21WBPerson1971EventImportedInitial conversion from geneace
229 Jan 2010 14:16:16WBPerson2970Name_changeCGC_namecars-1
Other_namecrs-1
StatusLive
Gene_infoBiotypeSO:0001217
Gene_classcars
Allele (97)
StrainWBStrain00036845
RNASeq_FPKM (74)
GO_annotation (17)
Ortholog (41)
ParalogWBGene00000801Caenorhabditis elegansFrom_analysismodENCODE_Pseudogenes
Structured_descriptionConcise_descriptioncars-1 encodes a predicted cytoplasmic cysteinyl-tRNA synthetase (CysRS), a class I aminoacyl-tRNA synthetase that catalyzes the attachment of cysteine to its cognate tRNA and is thus required for protein biosynthesis; CARS-1 is essential for embryonic and larval development, and is required for molting and a normal rate of postembryonic development.Paper_evidenceWBPaper00004402
WBPaper00004424
Curator_confirmedWBPerson1843
Date_last_updated03 Nov 2015 00:00:00
Automated_descriptionPredicted to enable ATP binding activity and cysteine-tRNA ligase activity. Predicted to be involved in cysteinyl-tRNA aminoacylation. Predicted to be located in cytoplasm. Is an ortholog of human CARS1 (cysteinyl-tRNA synthetase 1).Paper_evidenceWBPaper00065943
Curator_confirmedWBPerson324
WBPerson37462
Inferred_automaticallyThis description was generated automatically by a script based on data from the WS291 version of WormBase
Date_last_updated29 Nov 2023 00:00:00
Molecular_infoCorresponding_CDSY23H5A.7b
Y23H5A.7c
Corresponding_CDS_historyY23H5A.7a:wp282
Y23H5A.7b:wp282
Corresponding_transcriptY23H5A.7b.1
Y23H5A.7c.1
Other_sequence (60)
Associated_feature (12)
Experimental_infoRNAi_resultWBRNAi00095773Inferred_automaticallyRNAi_primary
WBRNAi00094332Inferred_automaticallyRNAi_primary
WBRNAi00066875Inferred_automaticallyRNAi_primary
WBRNAi00085742Inferred_automaticallyRNAi_primary
WBRNAi00096321Inferred_automaticallyRNAi_primary
WBRNAi00066874Inferred_automaticallyRNAi_primary
WBRNAi00055704Inferred_automaticallyRNAi_primary
WBRNAi00026627Inferred_automaticallyRNAi_primary
WBRNAi00064211Inferred_automaticallyRNAi_primary
WBRNAi00094448Inferred_automaticallyRNAi_primary
WBRNAi00094074Inferred_automaticallyRNAi_primary
WBRNAi00096301Inferred_automaticallyRNAi_primary
WBRNAi00096570Inferred_automaticallyRNAi_primary
WBRNAi00096901Inferred_automaticallyRNAi_primary
WBRNAi00026628Inferred_automaticallyRNAi_primary
WBRNAi00096404Inferred_automaticallyRNAi_primary
WBRNAi00085416Inferred_automaticallyRNAi_primary
WBRNAi00004563Inferred_automaticallyRNAi_primary
WBRNAi00096487Inferred_automaticallyRNAi_primary
WBRNAi00055703Inferred_automaticallyRNAi_primary
WBRNAi00004566Inferred_automaticallyRNAi_primary
WBRNAi00064185Inferred_automaticallyRNAi_primary
WBRNAi00116639Inferred_automaticallyRNAi_primary
WBRNAi00097777Inferred_automaticallyRNAi_primary
WBRNAi00096962Inferred_automaticallyRNAi_primary
Expr_patternExpr1015575
Expr1030499
Expr1159226
Expr2009721
Expr2027960
Drives_constructWBCnstr00037987
Construct_productWBCnstr00037987
Microarray_results (34)
Expression_clusterWBPaper00028451:Low_abundance_spermatogenesis_enriched
WBPaper00031040:TGF-beta_adult_downregulated
WBPaper00035073:mitochondria_protein
WBPaper00035211:age-1_vs_N2_downregulated
WBPaper00037047:aging_accelerated_insoluble_protein
WBPaper00037047:insoluble_protein
WBPaper00037950:AVE-neuron_L1-larva_expressed
WBPaper00037950:bodywall-muscle_L2-larva_expressed
WBPaper00037950:CEP-sheath-cells_Day1-adult_expressed
WBPaper00037950:coelomocytes_L1-larva_expressed
WBPaper00037950:coelomocytes_L2-larva_expressed
WBPaper00037950:GABAergic-motor-neurons_L2-larva_expressed
WBPaper00037950:glr-1(+)-neurons_L2-larva_expressed
WBPaper00037950:intestine_L2-larva_expressed
WBPaper00038118:aak-2(gt33)_upregulated
WBPaper00038289:oocyte_protein
WBPaper00044656:tatn-1(qd182)_downregulated
WBPaper00044736:flat_dev_expression
WBPaper00045521:Gender_Neutral
WBPaper00045571:germline-ablation_downregulated
WBPaper00048988:neuron_expressed
WBPaper00049217:TCER-1_downregulated
WBPaper00049545:jmjd-3.1(+)_downregulated
WBPaper00049545:sur-5p-jmjd-1.2(+)_downregulated
WBPaper00050344:ASER-neuron_enriched
WBPaper00050488:20C_vs_25C_regulated_N2_adult
WBPaper00050488:adult_vs_dauer_regulated_N2_20C
WBPaper00050488:mir-34(gk437)_vs_mir-34(OverExpression)_regulated_adult_25C
WBPaper00050488:mir-34(gk437)_vs_mir-34(OverExpression)_regulated_dauer_20C
WBPaper00050488:mir-34(OverExpression)_vs_N2_regulated_adult_20C
WBPaper00050488:N2_vs_mir-34(gk437)_regulated_dauer_20C
WBPaper00050488:N2_vs_mir-34(OverExpression)_regulated_adult_25C
WBPaper00050859:downregulated_P-granule(-)GFP(+)_vs_control_day2-adult
WBPaper00050859:downregulated_P-granule(-)GFP(-)_vs_control_day2-adult
WBPaper00050990:arcade_intestinal-valve_expressed
WBPaper00050990:GABAergic-neuron_expressed
WBPaper00050990:hypodermis_expressed
WBPaper00050990:intestine_expressed
WBPaper00050990:NMDA-neuron_expressed
WBPaper00051039:germline_enriched
WBPaper00051245:body-wall-muscle_cytoplasm_expressed
WBPaper00051245:epidermis_cytoplasm_expressed
WBPaper00051245:epidermis_nucleus_expressed
WBPaper00051245:intestine_cytoplasm_expressed
WBPaper00051245:intestine_nucleus_expressed
WBPaper00051245:pharyngeal-muscle_cytoplasm_expressed
WBPaper00051555:atm-1(gk186)_regulated_protein
WBPaper00051558:aging_regulated
WBPaper00052884:emb-4(hc60)_downregulated
WBPaper00053184:sma-2(rax5)_downregulated
WBPaper00053184:sma-4(rax3)_downregulated
WBPaper00053302:zidovudine_72h_regulated
WBPaper00053388:dauer_regulated_Cluster3
WBPaper00053606:N2_vs_elt-2(ca15)_upregulated
WBPaper00053615:SMO-1_target
WBPaper00053810:daf-2(e1370)_downregulated
WBPaper00053810:nuo-6(qm200)_downregulated
WBPaper00053814:25C_downregulated_OP50
WBPaper00053814:25C_downregulated_PY79
WBPaper00055648:germline_expressed
WBPaper00055971:nhl-2(ok818)_25C_upregulated
WBPaper00056090:E.faecalis_downregulated_hpx-2(dg047)
WBPaper00056275:P.aeruginosa_downregulated
WBPaper00056275:P.aeruginosa_upregulated
WBPaper00056443:sek-1(km4)_downregulated
WBPaper00056826:SGP_biased
WBPaper00057288:iff-1(RNAi)_downregulated_transcript
WBPaper00058598:sin-3(tm1276)_downregulated
WBPaper00059174:MEG-3_interacting
WBPaper00059328:mrps-5(RNAi)_downregulated_mRNA
WBPaper00059763:neuron_expressed
WBPaper00061203:sin-3(tm1276)_upregulated
WBPaper00061340:g1A_parent
WBPaper00061340:hmc_and_homolog
WBPaper00061340:Intestinal_and_rectal_muscle
WBPaper00061340:mc1
WBPaper00061340:mc3
WBPaper00061340:Pharyngeal_marginal_cell
WBPaper00061340:pm6
WBPaper00061340:pm7
WBPaper00061527:dld-1-skn-1_16701
WBPaper00061651:Distal_tip_cell_enriched
WBPaper00062325:muscle_depleted_coding-RNA
WBPaper00062669:extracellular-vesicle_protein
WBPaper00064005:starvation_upregulated_N2_mRNA
WBPaper00064315:mes-4(bn73)_downregulated_EGCs
WBPaper00064716:paraquat_upregulated
WBPaper00065373:Cisplatin_downregulated_WT
WBPaper00065841:89_0
WBPaper00065993:glp-1(e2141)_downregulated
cgc4489_group_1
cgc4489_group_2
WBPaper00005475:Aging-regulated
WBPaper00025141:N2_Expressed_Genes
WBPaper00025141:unc-4::GFP_Expressed_Genes
WBPaper00026929:sir-2.1_overexpression_regulated
WBPaper00026980:intestine_enriched
WBPaper00031832:slr-2_regulated
WBPaper00035905:FBF-1_Associated
WBPaper00041174:genotypic
WBPaper00041174:genotypic_prime
WBPaper00041606:CE_B.thuringiensis-DB27_regulated
WBPaper00041606:CE_X.nematophila_regulated
WBPaper00045263:nuo-6(qm200)_downregulated
WBPaper00048637:lin-35(n745)_starvation_downregulated
[cgc5767]:expression_class_M
[cgc5767]:expression_class_SM
Interaction (91)
Map_infoMapIPosition-8.11751Error0.030644
PositivePositive_cloneY23H5AInferred_automaticallyFrom CDS info
From sequence, transcript, pseudogene data
Pseudo_map_position
ReferenceWBPaper00038491
WBPaper00041771
WBPaper00055090
WBPaper00064339
Remarkdl1 : probably cytoplasmic
Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC.CGC_data_submission
MethodGene