WormBase Tree Display for Gene: WBGene00018150

WBGene00018150 SMap: S_parent: Sequence: F37C12
  Identity: Version: 3
    Name: CGC_name: epg-4 Paper_evidence: WBPaper00036384
          Person_evidence: WBPerson716
      Sequence_name: F37C12.2
      Molecular_name: F37C12.2
        F37C12.2.1
        CE00741
        F37C12.2.2
        F37C12.2.3
      Other_name: eip-24
        CELE_F37C12.2 Accession_evidence: NDB BX284603
      Public_name: epg-4
    DB_info: Database (10)
    Species: Caenorhabditis elegans
    History: Version_change: 1 28 May 2004 13:30:59 WBPerson1971 Event: Imported: Initial conversion from CDS class of stlace from WS125
        2 18 Jul 2008 11:30:00 WBPerson2970 Name_change: CGC_name: eip-24
        3 21 Jun 2010 10:25:58 WBPerson2970 Name_change: CGC_name: epg-4
                Other_name: eip-24
    Status: Live
  Gene_info: Biotype: SO:0001217
    Gene_class: epg
    Allele (25)
    RNASeq_FPKM (74)
    GO_annotation: 00067222
      00067223
      00067224
      00067225
      00067226
      00067227
      00067228
      00067229
      00067230
      00067231
    Contained_in_operon: CEOP3416
    Ortholog: WBGene00030156 Caenorhabditis briggsae From_analysis: Hillier-set
            OrthoMCL
            OMA
            Inparanoid_8
            WormBase-Compara
      WBGene00054716 Caenorhabditis remanei From_analysis: OMA
            TreeFam
            Inparanoid_8
            WormBase-Compara
      WBGene00150748 Caenorhabditis brenneri From_analysis: OMA
            TreeFam
            Inparanoid_8
            WormBase-Compara
      WBGene00122993 Caenorhabditis japonica From_analysis: Inparanoid_8
            WormBase-Compara
      WBGene00056664 Caenorhabditis remanei From_analysis: Inparanoid_8
            WormBase-Compara
      WBGene00224154 Brugia malayi From_analysis: WormBase-Compara
      CBOVI.g5652 Caenorhabditis bovis From_analysis: WormBase-Compara
      CSP21.g245 Caenorhabditis parvicauda From_analysis: WormBase-Compara
      CSP26.g4657 Caenorhabditis zanzibari From_analysis: WormBase-Compara
      CSP28.g16430 Caenorhabditis panamensis From_analysis: WormBase-Compara
      CSP29.g23900 Caenorhabditis becei From_analysis: WormBase-Compara
      CSP32.g9762 Caenorhabditis sulstoni From_analysis: WormBase-Compara
      CSP38.g4717 Caenorhabditis quiockensis From_analysis: WormBase-Compara
      CSP39.g684 Caenorhabditis waitukubuli From_analysis: WormBase-Compara
      CSP40.g16161 Caenorhabditis tribulationis From_analysis: WormBase-Compara
      Cang_2012_03_13_01078.g15612 Caenorhabditis angaria From_analysis: WormBase-Compara
      Cni-epg-4 Caenorhabditis nigoni From_analysis: WormBase-Compara
      Csp11.Scaffold489.g2043 Caenorhabditis tropicalis From_analysis: WormBase-Compara
      Csp11.Scaffold629.g9985 Caenorhabditis tropicalis From_analysis: WormBase-Compara
      Csp5_scaffold_00350.g9918 Caenorhabditis sinica From_analysis: WormBase-Compara
      FL83_22010 Caenorhabditis latens From_analysis: WormBase-Compara
      GCK72_009831 Caenorhabditis remanei From_analysis: WormBase-Compara
      GCK72_019987 Caenorhabditis remanei From_analysis: WormBase-Compara
      OTIPU.nOt.2.0.1.g11613 Oscheius tipulae From_analysis: WormBase-Compara
      Pan_g11034 Panagrellus redivivus From_analysis: WormBase-Compara
      Sp34_30239710 Caenorhabditis inopinata From_analysis: WormBase-Compara
      chrIII_pilon.g8098 Caenorhabditis elegans From_analysis: WormBase-Compara
      WBGene00244736 Onchocerca volvulus From_analysis: WormBase-Compara
      WBGene00261949 Strongyloides ratti From_analysis: WormBase-Compara
      WBGene00297234 Trichuris muris From_analysis: WormBase-Compara
      FB:FBgn0031635 Drosophila melanogaster From_analysis: EnsEMBL-Compara
            Hieranoid
            Inparanoid
            OrthoFinder
            OrthoInspector
            Panther
            PhylomeDB
            SonicParanoid
      ZFIN:ZDB-GENE-050417-457 Danio rerio From_analysis: EnsEMBL-Compara
            Hieranoid
            Inparanoid
            OrthoFinder
            OrthoInspector
            Panther
            PhylomeDB
            SonicParanoid
      HGNC:13276 Homo sapiens From_analysis: EnsEMBL-Compara
            Hieranoid
            Inparanoid
            OrthoFinder
            OrthoInspector
            Panther
            PhylomeDB
            SonicParanoid
      MGI:108090 Mus musculus From_analysis: EnsEMBL-Compara
            Hieranoid
            Inparanoid
            OrthoFinder
            OrthoInspector
            Panther
            PhylomeDB
            SonicParanoid
      RGD:1309868 Rattus norvegicus From_analysis: EnsEMBL-Compara
            Hieranoid
            Inparanoid
            OrthoFinder
            OrthoInspector
            Panther
            PhylomeDB
            SonicParanoid
    Structured_description: Automated_description: Involved in macroautophagy and negative regulation of autophagosome assembly. Located in endoplasmic reticulum. Expressed in several structures, including body wall musculature; head; hypodermis; pharyngeal muscle cell; and tail. Is an ortholog of human EI24 (EI24 autophagy associated transmembrane protein). Paper_evidence: WBPaper00065943
          Curator_confirmed: WBPerson324
            WBPerson37462
          Inferred_automatically: This description was generated automatically by a script based on data from the WS291 version of WormBase
          Date_last_updated: 29 Nov 2023 00:00:00
  Molecular_info: Corresponding_CDS: F37C12.2
    Corresponding_transcript: F37C12.2.1
      F37C12.2.2
      F37C12.2.3
    Other_sequence: CRC04049_1
      JI170818.1
    Associated_feature: WBsf645323
      WBsf225209
  Experimental_info: RNAi_result (12)
    Expr_pattern: Expr9074
      Expr14804
      Expr1014040
      Expr1037817
      Expr1150496
      Expr2011343
      Expr2029579
    Drives_construct: WBCnstr00007050
      WBCnstr00013703
      WBCnstr00026744
      WBCnstr00040924
    Construct_product: WBCnstr00006907
      WBCnstr00007050
      WBCnstr00013703
      WBCnstr00018686
      WBCnstr00026744
      WBCnstr00040924
    Microarray_results (22)
    Expression_cluster: WBPaper00031040:TGF-beta_adult_downregulated
      WBPaper00035269:cde-1_regulated
      WBPaper00036375:enriched_in_PVD_OLL
      WBPaper00037950:A-class-motor-neurons_L2-larva_expressed
      WBPaper00037950:BAG-neuron_blastula-embryo_expressed
      WBPaper00037950:bodywall-muscle_L2-larva_expressed
      WBPaper00037950:CEP-sheath-cells_Day1-adult_expressed
      WBPaper00037950:coelomocytes_L1-larva_expressed
      WBPaper00037950:dopaminergic-neurons_L1-larva_expressed
      WBPaper00037950:dopaminergic-neurons_L3-L4-larva_expressed
      WBPaper00037950:excretory-cell_L2-larva_expressed
      WBPaper00037950:GABAergic-motor-neurons_L2-larva_expressed
      WBPaper00037950:germline-precursors_blastula-embryo_expressed
      WBPaper00037950:hypodermis_L3-L4-larva_expressed
      WBPaper00037950:intestine_L1-larva_expressed
      WBPaper00037950:intestine_L2-larva_expressed
      WBPaper00044426:rotenone_24h_upregulated
      WBPaper00044736:flat_dev_expression
      WBPaper00044760:germline_specific
      WBPaper00045729:gld-2(RNAi)_downregulated
      WBPaper00045774:clk-1_upregulated
      WBPaper00046509:htz-1(ok3099)_upregulated
      WBPaper00048988:neuron_expressed
      WBPaper00050488:20C_vs_25C_regulated_N2_adult
      WBPaper00050488:adult_vs_dauer_regulated_N2_20C
      WBPaper00050990:body-muscle_expressed
      WBPaper00050990:GABAergic-neuron_expressed
      WBPaper00050990:intestine_expressed
      WBPaper00050990:pharynx_expressed
      WBPaper00051039:germline_enriched
      WBPaper00051245:epidermis_cytoplasm_expressed
      WBPaper00051245:intestine_cytoplasm_expressed
      WBPaper00053295:lin-22(icb38)_downregulated
      WBPaper00053302:stavudine_24h_regulated
      WBPaper00053302:zidovudine_72h_regulated
      WBPaper00053388:dauer_regulated_Cluster2
      WBPaper00053599:female_vs_male_upregulated
      WBPaper00053798:nhr-49(nr2041)_tBOOH_upregulated
      WBPaper00054571:BPA_F3_germline_upregulated
      WBPaper00055013:hmg-3(bar24)_upregulated
      WBPaper00055648:germline_expressed
      WBPaper00055862:antimycin_damt-1(gk961032)_regulated
      WBPaper00056275:P.aeruginosa_upregulated
      WBPaper00056275:P.aeruginosa_upregulated_atf-7(qd22qd130)_dependent
      WBPaper00056275:P.aeruginosa_upregulated_pmk-1(km25)_dependent
      WBPaper00056471:aak-1(tm1944);aak-2(ok524)_downregulated
      WBPaper00056471:S.aureus-4h_upregulated_N2
      WBPaper00057288:Cold_upregulated_transcript
      WBPaper00057288:iff-1(RNAi)_upregulated_transcript
      WBPaper00058691:sin-3(tm1276)_upregulated
      WBPaper00059174:MEG-3_interacting
      WBPaper00059356:BAZ-2_SET-6_interacting
      WBPaper00059471:EGL-43_interacting
      WBPaper00059763:neuron_expressed
      WBPaper00059895:wounding_upregulated
      WBPaper00060683:hlh-11(ko1)_downregulated
      WBPaper00060909:atfs-1(cmh15)_upregulated
      WBPaper00061007:S.aquatilis_downregulated
      WBPaper00061439:unc-30(ok613)_downregulated_P.aeruginosa-infection
      WBPaper00061527:F31C3.4_6048-cutc-1_15804
      WBPaper00062345:bortezomib_4h_upregulated_zip-1(jy13)
      WBPaper00062590:Aging_downregulated_hypodermis
      WBPaper00062669:extracellular-vesicle_protein
      WBPaper00064005:starvation_upregulated_N2_mRNA
      WBPaper00064071:NHR-49_interacting
      WBPaper00064088:Day-1-adult_vs_L4_upregulated_daf-16(mu86);glp-1(e2141)
      WBPaper00064088:Day-1-adult_vs_L4_upregulated_glp-1(e2141)
      WBPaper00064088:Day-3-adult_vs_L4_upregulated_daf-16(mu86);glp-1(e2141)
      WBPaper00064088:Day-3-adult_vs_L4_upregulated_glp-1(e2141)
      WBPaper00064130:Beta-Amyloid_upregulated_protein
      WBPaper00064716:paraquat_upregulated
      WBPaper00065074:glna(-)_upregulated
      WBPaper00065096:25C_vs_20C_upregulated
      WBPaper00065096:Day10_vs_Day1_upregulated
      WBPaper00065120:body-muscle-transcriptome
      WBPaper00065373:Cisplatin_upregulated_WT
      WBPaper00065975:P-body_vs_oocyte_enriched
      WBPaper00065975:P-body_vs_WholeAnimal_enriched
      WBPaper00066062:xrep-4(lax137)_upregulated
      WBPaper00066110:tetraploid_vs_diploid_downregulated
      cgc4386_cluster_5_4
      cgc4489_group_2
      WBPaper00025141:N2_Expressed_Genes
      WBPaper00025141:unc-4::GFP_Expressed_Genes
      WBPaper00026929:sir-2.1_overexpression_regulated
      WBPaper00026980:intestine_enriched
      WBPaper00032948:StarveUp2
      WBPaper00035084:L1_enriched_AIN-2_IP
      WBPaper00035227:heat_shock_regulated
      WBPaper00035905:FBF-1_Associated
      WBPaper00036130:mir-243_down_regulated
      WBPaper00036286:Pattern_F
      WBPaper00037611:GLD-2-associated
      WBPaper00037611:RNP-8-associated
      WBPaper00038231:Cry5B_1.5-fold_upregulated
      WBPaper00038231:Cry5B_2-fold_upregulated
      WBPaper00040603:tdp-1(lf)_down_vs_N2_FC_1.2
      WBPaper00041002:HF_3d_2.0mM_Down
      WBPaper00041606:CE_X.nematophila_regulated
      WBPaper00041939:control_vs_EtBr-exposed_48h
      WBPaper00041939:control_vs_UVC-EtBr-exposed_48h
      WBPaper00041939:control_vs_UVC-EtBr-exposed_51h
      WBPaper00041939:EtBr-exposed_vs_UVC-exposed_48h
      WBPaper00041939:UVC-EtBr-exposed_vs_UVC-exposed_48h
      WBPaper00042331:a-SWCNTs_downregulated
      WBPaper00045263:0.1mM-paraquat_upregulated
      WBPaper00045263:nuo-6(qm200)_upregulated
      WBPaper00047070:xpa-1_UV_upregulated
      WBPaper00048989:N2_rapamycin_downregulated
      WBPaper00053236:Starvation_regulated_GR1307
      WBPaper00053236:Starvation_regulated_N2
      [cgc5767]:expression_class_E
      [cgc5767]:expression_class_E_pi(83_min)
      [cgc5767]:expression_class_E_pi(101_min)
      [cgc5767]:expression_class_M
      [cgc5767]:expression_class_MD
      [cgc5767]:expression_class_MDE
      [cgc5767]:expression_class_MD_pd(41_min)
      [cgc5767]:expression_class_ME
    Interaction (42)
  Map_info: Map: III Position: -0.775725 Error: 0.000156
    Positive: Positive_clone: F37C12 Inferred_automatically: From sequence, transcript, pseudogene data
    Pseudo_map_position
  Reference: WBPaper00036384
    WBPaper00038491
    WBPaper00044390
    WBPaper00052108
    WBPaper00055090
    WBPaper00056693
    WBPaper00061251
  Remark: Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. CGC_data_submission
  Method: Gene