WormBase Tree Display for Gene: WBGene00010510

WBGene00010510 SMap: S_parent: Sequence: K02E11
  Identity: Version: 3
    Name: CGC_name: ent-3 Person_evidence: WBPerson1318
      Sequence_name: K02E11.1
      Molecular_name: K02E11.1
        K02E11.1.1
        CE37978
      Other_name: CELE_K02E11.1 Accession_evidence: NDB BX284605
      Public_name: ent-3
    DB_info: Database (11)
    Species: Caenorhabditis elegans
    History: Version_change: 1 26 May 2004 16:54:51 WBPerson1971 Event: Imported: Initial conversion from CDS class of WS125
        2 04 Nov 2004 16:11:20 WBPerson2970 Name_change: CGC_name: ent-3
        3 10 Jan 2005 12:17:44 WBPerson2970 Event: Acquires_merge: WBGene00001321
      Acquires_merge: WBGene00001321
    Status: Live
  Gene_info: Biotype: SO:0001217
    Gene_class: ent
    Allele (62)
    Strain: WBStrain00035587
      WBStrain00035945
    RNASeq_FPKM (74)
    GO_annotation: 00070402
      00070403
      00070404
      00070405
      00070406
      00117888
      00117889
      00117890
    Ortholog: WBGene00056993 Caenorhabditis remanei From_analysis: TreeFam
            Inparanoid_8
            WormBase-Compara
      WBGene00027353 Caenorhabditis briggsae From_analysis: Hillier-set
            OrthoMCL
            WormBase-Compara
      WBGene00143370 Caenorhabditis brenneri From_analysis: TreeFam
            Inparanoid_8
            WormBase-Compara
      WBGene00130128 Caenorhabditis japonica From_analysis: TreeFam
            WormBase-Compara
      WBGene00194322 Caenorhabditis brenneri From_analysis: TreeFam
            WormBase-Compara
      WBGene00164086 Caenorhabditis brenneri From_analysis: TreeFam
      WBGene00149983 Caenorhabditis brenneri From_analysis: TreeFam
      WBGene00060929 Caenorhabditis remanei From_analysis: TreeFam
      WBGene00030497 Caenorhabditis briggsae From_analysis: Inparanoid_8
      WBGene00136714 Caenorhabditis japonica From_analysis: Inparanoid_8
      WBGene00225202 Brugia malayi From_analysis: WormBase-Compara
      WBGene00229010 Brugia malayi From_analysis: WormBase-Compara
      CBOVI.g2169 Caenorhabditis bovis From_analysis: WormBase-Compara
      CSP21.g13279 Caenorhabditis parvicauda From_analysis: WormBase-Compara
      CSP21.g13280 Caenorhabditis parvicauda From_analysis: WormBase-Compara
      CSP26.g15171 Caenorhabditis zanzibari From_analysis: WormBase-Compara
      CSP28.g7684 Caenorhabditis panamensis From_analysis: WormBase-Compara
      CSP29.g10178 Caenorhabditis becei From_analysis: WormBase-Compara
      CSP31.g14355 Caenorhabditis uteleia From_analysis: WormBase-Compara
      CSP32.g9022 Caenorhabditis sulstoni From_analysis: WormBase-Compara
      CSP38.g17558 Caenorhabditis quiockensis From_analysis: WormBase-Compara
      CSP38.g17559 Caenorhabditis quiockensis From_analysis: WormBase-Compara
      CSP39.g24815 Caenorhabditis waitukubuli From_analysis: WormBase-Compara
      CSP40.g60 Caenorhabditis tribulationis From_analysis: WormBase-Compara
      Cnig_chr_V.g20708 Caenorhabditis nigoni From_analysis: WormBase-Compara
      Csp11.Scaffold630.g19970 Caenorhabditis tropicalis From_analysis: WormBase-Compara
      Csp5_scaffold_00407.g10910 Caenorhabditis sinica From_analysis: WormBase-Compara
      FL83_21625 Caenorhabditis latens From_analysis: WormBase-Compara
      GCK72_020338 Caenorhabditis remanei From_analysis: WormBase-Compara
      OTIPU.nOt.2.0.1.g11472 Oscheius tipulae From_analysis: WormBase-Compara
      OTIPU.nOt.2.0.1.g14362 Oscheius tipulae From_analysis: WormBase-Compara
      Pan_g10508 Panagrellus redivivus From_analysis: WormBase-Compara
      Pan_g10509 Panagrellus redivivus From_analysis: WormBase-Compara
      Pan_g22035 Panagrellus redivivus From_analysis: WormBase-Compara
      Sp34_50363500 Caenorhabditis inopinata From_analysis: WormBase-Compara
      Sp34_50363810 Caenorhabditis inopinata From_analysis: WormBase-Compara
      Sp34_50363820 Caenorhabditis inopinata From_analysis: WormBase-Compara
      Sp34_50364200 Caenorhabditis inopinata From_analysis: WormBase-Compara
      chrV_pilon.g16458 Caenorhabditis elegans From_analysis: WormBase-Compara
      WBGene00238646 Onchocerca volvulus From_analysis: WormBase-Compara
      WBGene00241620 Onchocerca volvulus From_analysis: WormBase-Compara
      WBGene00111315 Pristionchus pacificus From_analysis: WormBase-Compara
      WBGene00257475 Strongyloides ratti From_analysis: WormBase-Compara
      WBGene00257813 Strongyloides ratti From_analysis: WormBase-Compara
      WBGene00265373 Strongyloides ratti From_analysis: WormBase-Compara
      WBGene00293064 Trichuris muris From_analysis: WormBase-Compara
      SGD:S000000020 Saccharomyces cerevisiae From_analysis: EnsEMBL-Compara
            Hieranoid
            OrthoFinder
            Panther
      FB:FBgn0263916 Drosophila melanogaster From_analysis: EnsEMBL-Compara
            Hieranoid
            Inparanoid
            OrthoFinder
            OrthoInspector
            Panther
            PhylomeDB
      ZFIN:ZDB-GENE-050220-15 Danio rerio From_analysis: EnsEMBL-Compara
            Inparanoid
            OrthoInspector
            SonicParanoid
      ZFIN:ZDB-GENE-050913-138 Danio rerio From_analysis: EnsEMBL-Compara
            Inparanoid
            OrthoInspector
            SonicParanoid
      ZFIN:ZDB-GENE-130415-4 Danio rerio From_analysis: EnsEMBL-Compara
            Inparanoid
            OrthoInspector
            SonicParanoid
      HGNC:11004 Homo sapiens From_analysis: EnsEMBL-Compara
            Inparanoid
            OrthoInspector
            SonicParanoid
      HGNC:23096 Homo sapiens From_analysis: EnsEMBL-Compara
            Inparanoid
            OrthoInspector
            SonicParanoid
      MGI:1927073 Mus musculus From_analysis: EnsEMBL-Compara
            Inparanoid
            OrthoInspector
            SonicParanoid
      MGI:1918529 Mus musculus From_analysis: EnsEMBL-Compara
            Inparanoid
            OrthoInspector
            SonicParanoid
      RGD:61899 Rattus norvegicus From_analysis: EnsEMBL-Compara
            Inparanoid
            OrthoInspector
            SonicParanoid
      RGD:69296 Rattus norvegicus From_analysis: EnsEMBL-Compara
            Inparanoid
            OrthoInspector
            SonicParanoid
      RGD:727811 Rattus norvegicus From_analysis: EnsEMBL-Compara
            Inparanoid
            OrthoInspector
            SonicParanoid
    Paralog: WBGene00001320 Caenorhabditis elegans From_analysis: TreeFam
            Panther
            WormBase-Compara
      WBGene00008123 Caenorhabditis elegans From_analysis: TreeFam
            Panther
            WormBase-Compara
      WBGene00009499 Caenorhabditis elegans From_analysis: TreeFam
            Panther
            WormBase-Compara
      WBGene00009686 Caenorhabditis elegans From_analysis: TreeFam
            Panther
            WormBase-Compara
      WBGene00017532 Caenorhabditis elegans From_analysis: TreeFam
            Panther
            WormBase-Compara
      WBGene00010701 Caenorhabditis elegans From_analysis: Panther
            WormBase-Compara
    Structured_description: Automated_description: Predicted to enable nucleoside transmembrane transporter activity. Predicted to be involved in nucleoside transmembrane transport. Predicted to be located in plasma membrane. Human ortholog(s) of this gene implicated in histiocytosis-lymphadenopathy plus syndrome. Is an ortholog of human SLC29A2 (solute carrier family 29 member 2) and SLC29A3 (solute carrier family 29 member 3). Paper_evidence: WBPaper00065943
          Curator_confirmed: WBPerson324
            WBPerson37462
          Inferred_automatically: This description was generated automatically by a script based on data from the WS291 version of WormBase
          Date_last_updated: 29 Nov 2023 00:00:00
  Disease_info: Potential_model: DOID:0111278 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:23096)
  Molecular_info: Corresponding_CDS: K02E11.1
    Corresponding_CDS_history: K02E11.1:wp138
    Corresponding_transcript: K02E11.1.1
    Other_sequence: CRC00025_1
      CR06836
      CJC16007_1
      CR02783
      CR00015
      CRC01103_1
      CRC02587_1
    Associated_feature: WBsf1001968
      WBsf1001969
      WBsf1001970
      WBsf1001971
      WBsf1001972
      WBsf1001973
      WBsf1020813
      WBsf1020814
      WBsf1020815
      WBsf234918
  Experimental_info: RNAi_result: WBRNAi00016459 Inferred_automatically: RNAi_primary
      WBRNAi00001923 Inferred_automatically: RNAi_primary
      WBRNAi00049711 Inferred_automatically: RNAi_primary
    Expr_pattern: Expr1024929
      Expr1153429
      Expr2011325
      Expr2029561
    Drives_construct: WBCnstr00031366
    Construct_product: WBCnstr00031366
    Microarray_results (18)
    Expression_cluster: WBPaper00033065:cyc-1(RNAi)_upregulated
      WBPaper00037950:CEP-sheath-cells_Day1-adult_expressed
      WBPaper00037950:germline-precursors_blastula-embryo_expressed
      WBPaper00038237:age-1_upregulated_intestine_rescue
      WBPaper00038237:age-1_upregulated_neuron_rescue
      WBPaper00038237:age-1_upregulated_nontransgenic
      WBPaper00038438:E.faecalis_24hr_upregulated_RNAseq
      WBPaper00038438:E.faecalis_24hr_upregulated_TilingArray
      WBPaper00038438:S.marcescens_24hr_upregulated_RNAseq
      WBPaper00042194:nhr-114(RNAi)_upregulated
      WBPaper00042215:wdr-23(tm1817)_upregulated
      WBPaper00042477:rsr-2(RNAi)_downregulated_TilingArray
      WBPaper00042561:smgl-1(RNAi)_upregulated
      WBPaper00044037:eat-2_upregulated
      WBPaper00044260:1-methylnicotinamide_upregulated
      WBPaper00044260:nicotinc-acid_upregulated
      WBPaper00044316:CH3HgCl_7.5uM_upregulated
      WBPaper00044426:rotenone_10day_downregulated
      WBPaper00044578:reduced-humidity_downregulated_microarray
      WBPaper00044736:rising_dev_expression
      WBPaper00044760:germline_specific
      WBPaper00045050:csr-1(hypomorph)_upregulated
      WBPaper00045521:Spermatogenic
      WBPaper00045729:gld-2(RNAi)_upregulated
      WBPaper00045774:clk-1_downregulated
      WBPaper00046497:B.thuringiensis_0.1mix_upregulated_12h
      WBPaper00046497:B.thuringiensis_0.5mix_upregulated_12h
      WBPaper00046805:csr-1(RNAi)_upregulated_Set1
      WBPaper00046805:csr-1(RNAi)_upregulated_Set2
      WBPaper00048611:MnCl2_downregulated
      WBPaper00048923:Aging_regulated
      WBPaper00049498:npr-1(ur89)_regulated_2
      WBPaper00049920:Glucose-Diet_upregulated_hyl-2(tm2031)
      WBPaper00049920:Glucose-Diet_upregulated_N2
      WBPaper00050231:male_enriched
      WBPaper00050370:dpy-21(e428)_L3_downregulated
      WBPaper00050488:20C_vs_25C_regulated_N2_adult
      WBPaper00050488:adult_vs_dauer_regulated_N2_20C
      WBPaper00050488:N2_vs_mir-34(gk437)_regulated_dauer_20C
      WBPaper00050522:mafr-1(tm6082)_downregulated
      WBPaper00050743:elli-1(sam-3)_upregulated
      WBPaper00050801:DAF-12_dauer_regulome
      WBPaper00050801:DAF-16_dauer_regulome
      WBPaper00050859:upregulated_P-granule(-)GFP(+)_vs_control_day2-adult
      WBPaper00050859:upregulated_P-granule(-)GFP(-)_vs_control_day1-adult
      WBPaper00050859:upregulated_P-granule(-)GFP(-)_vs_control_day2-adult
      WBPaper00050990:hypodermis_enriched
      WBPaper00050990:hypodermis_expressed
      WBPaper00051265:F4_hrde-1(tm1200)_upregulated
      WBPaper00051404:alg-2(ok304)_downregulated
      WBPaper00053184:sma-2(rax5)_upregulated
      WBPaper00053184:sma-4(rax3)_upregulated
      WBPaper00053302:stavudine_24h_regulated
      WBPaper00053302:zidovudine_72h_regulated
      WBPaper00053318:Aging_downregulated_mRNA_N2
      WBPaper00053318:mir-71(n4115)_downregulated_mRNA
      WBPaper00053388:dauer_regulated_Cluster6
      WBPaper00053599:female_vs_male_downregulated
      WBPaper00054872:egl-9(sa307)_downregulated
      WBPaper00055354:Rapamycin-Allantoin_upregulated
      WBPaper00055354:Rapamycin-Metformin_upregulated
      WBPaper00055354:Rapamycin-Psora_upregulated
      WBPaper00055386:daf-2(e1370)_upregulated
      WBPaper00055386:eat-2(ad465)_upregulated
      WBPaper00055482:pmt-2(RNAi)_upregulated
      WBPaper00055648:sperm_expressed
      WBPaper00055804:FBF-1-FBF-2-associated_spermatogenic-enriched
      WBPaper00055862:antimycin_damt-1(gk961032)_regulated
      WBPaper00055971:nhl-2(ok818)_20C_downregulated
      WBPaper00055971:nhl-2(ok818)_25C_downregulated
      WBPaper00056034:pals-22(jy3)_upregulated
      WBPaper00056090:E.faecalis_upregulated_hpx-2(dg047)
      WBPaper00056090:E.faecalis_upregulated_N2
      WBPaper00056161:male_enriched_siRNA
      WBPaper00056167:Cry5B_downregulated
      WBPaper00056169:rrf-3(pk1426)_downregulated_L3
      WBPaper00056290:hsp-6(mg585)_downregulated
      WBPaper00056471:aak-1(tm1944);aak-2(ok524)_downregulated
      WBPaper00056471:flcn-1(ok975)_downregulated
      WBPaper00056809:smn-1(ok355)_downregulated
      WBPaper00056997:nmad-1(ok3133)_upregulated_germline_25C
      WBPaper00057068:numr-1(RNAi)_upregulated_Cadmium
      WBPaper00058948:npr-8(ok1439)_downregulated_OP50
      WBPaper00058948:PA14_upregulated
      WBPaper00059117:B.subtilis_upregulated
      WBPaper00059328:mrps-5(RNAi)_downregulated_mRNA
      WBPaper00059728:5ug_cholesterol_upregulated
      WBPaper00059728:20ug_cholesterol_upregulated
      WBPaper00060358:B.thuringiensis_pathogen_regulated_elt-2(RNAi)
      WBPaper00060358:B.thuringiensis_pathogen_regulated_N2
      WBPaper00060399:pqm-1(ok485)_upregulated_CoCl2_6hr
      WBPaper00060445:ikb-1(nr2027)_upregulated_L4
      WBPaper00060445:nfki-1(cer1)_ikb-1(nr2027)_upregulated_L4
      WBPaper00060445:nfki-1(cer1)_upregulated_L4
      WBPaper00060526:plp-1(ok2155)_upregulated
      WBPaper00060683:hlh-11(ko1)_upregulated
      WBPaper00060811:L1_vs_adult_downregulated_neural
      WBPaper00060909:atfs-1(cmh15)_upregulated
      WBPaper00060921:cat-2(e1112)_downregulated
      WBPaper00061081:E.faecalis_upregulated_N2
      WBPaper00061274:hypergravity_10xg_downregulated
      WBPaper00061340:BAG
      WBPaper00061341:28C_24h_downregulated
      WBPaper00061424:Diet_MYb120_upregulated
      WBPaper00061424:Diet_MYb131_upregulated
      WBPaper00061439:unc-30(ok613)_downregulated
      WBPaper00061479:hda-1(ne4752)_upregulated
      WBPaper00061479:mep-1(ne4629)_upregulated
      WBPaper00061479:prg-1(tm872)_upregulated
      WBPaper00061479:ubc-9(ne4833)_upregulated
      WBPaper00061527:Y40H4A.2-ZK1053.2
      WBPaper00062078:NMR-HspB1_regulated
      WBPaper00062156:jmjd-5(zr1234)_upregulated
      WBPaper00062456:doxycycline_upregulated_CB4856_transcript
      WBPaper00062456:doxycycline_upregulated_N2_transcript
      WBPaper00062585:hlh-26(ok1453)_upregulated_E.faecium
      WBPaper00064088:Day-1-adult_vs_L4_downregulated_glp-1(e2141)
      WBPaper00064088:Day-1-adult_vs_L4_upregulated_fem-3(q20)
      WBPaper00064088:Day-3-adult_vs_L4_downregulated_glp-1(e2141)
      WBPaper00064088:Day-3-adult_vs_L4_upregulated_fem-3(q20)
      WBPaper00064130:Beta-Amyloid_24h_upregulated_mRNA
      WBPaper00064229:B.thuringiensis-Cry5Ba_upregulated
      WBPaper00064502:nhr-23(kry61);spe-44(fx110)_downregulated
      WBPaper00064539:nhr-114(gk849)_downregulated
      WBPaper00064716:paraquat_downregulated
      WBPaper00065096:25C_vs_20C_downregulated
      WBPaper00065096:Day10_vs_Day1_downregulated
      WBPaper00065096:npr-8(ok1439)_upregulated_Day1_25C
      WBPaper00065096:npr-8(ok1439)_upregulated_Day10_20C
      WBPaper00065096:npr-8(ok1439)_upregulated_Day10_25C
      WBPaper00065581:hpk-1(pk1393)_upregulated
      WBPaper00065746:eat-2(ad1113)_downregulated
      WBPaper00065749:Heat-Shock_upregulated_endu-2(tm4977)
      WBPaper00065749:Heat-Shock_upregulated_N2
      WBPaper00065984:pals-17(syb3980)_upregulated
      WBPaper00066038:mip-1(how5)_upregulated
      WBPaper00066085:hda-3(ok1991)_upregulated
      WBPaper00066093:E.coli-purE_upregulated
      WBPaper00066110:Cisplatin_upregulated_diploid
      WBPaper00066110:Doxorubicin_upregulated_diploid
      WBPaper00066110:tetraploid_vs_diploid_upregulated
      WBPaper00066118:cyclobutrifluram_upregulated
      WBPaper00066232:ash-2(RNAi)_downregulated_WT
      cgc4489_group_10
      WBPaper00026929:sir-2.1_overexpression_regulated
      WBPaper00035873:dpy-9_regulated
      WBPaper00035873:dpy-10_regulated
      WBPaper00036286:Pattern_E
      WBPaper00038172:aak-2overexpression_up_regulated
      WBPaper00041174:environmental
      WBPaper00041174:environmental_prime
      WBPaper00042258:DA1877_upregulated_GravidAdult
      WBPaper00045263:0.1mM-paraquat_downregulated
      WBPaper00045263:isp-1(qm150)_downregulated
      WBPaper00045263:nuo-6(qm200)_downregulated
      WBPaper00045263:ProLongevity-mtROS_downregulated
      WBPaper00045673:colistin_downregulated
      WBPaper00048989:N2_allantoin_downregulated
      WBPaper00048989:N2_rapamycin_upregulated
      [cgc6390]:Cluster_D
      [cgc6390]:spermatogenesis-enriched
    Interaction (29)
  Map_info: Map: V Position: 6.2055 Error: 0.001795
    Positive: Positive_clone: K02E11 Inferred_automatically: From sequence, transcript, pseudogene data
    Mapping_data: Multi_point: 5653
    Pseudo_map_position
  Reference: WBPaper00011438
    WBPaper00018608
    WBPaper00024337
    WBPaper00038491
    WBPaper00055090
  Remark: Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. CGC_data_submission
  Method: Gene