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WormBase Tree Display for Gene: WBGene00016192

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Name Class

WBGene00016192SMapS_parentSequenceC28H8
IdentityVersion2
NameCGC_namebcl-7Person_evidenceWBPerson426
Sequence_nameC28H8.1
Molecular_nameC28H8.1
C28H8.1.1
CE01820
Other_nameCELE_C28H8.1Accession_evidenceNDBBX284603
Public_namebcl-7
DB_infoDatabaseAceViewgene3H17
WormQTLgeneWBGene00016192
WormFluxgeneWBGene00016192
NDBlocus_tagCELE_C28H8.1
PanthergeneCAEEL|WormBase=WBGene00016192|UniProtKB=Q09242
familyPTHR12767
NCBIgene175838
RefSeqproteinNM_065886.6
SwissProtUniProtAccQ09242
TREEFAMTREEFAM_IDTF317441
UniProt_GCRPUniProtAccQ09242
SpeciesCaenorhabditis elegans
HistoryVersion_change128 May 2004 13:30:57WBPerson1971EventImportedInitial conversion from CDS class of stlace from WS125
220 May 2014 11:44:19WBPerson2970Name_changeCGC_namebcl-7
StatusLive
Gene_infoBiotypeSO:0001217
Gene_classbcl
Allele (15)
RNASeq_FPKM (74)
GO_annotation00053020
00053021
00053022
00053023
00053024
Ortholog (43)
Structured_descriptionConcise_descriptionbcl-7 encodes the sole C. elegans member of the BCL7 family of proteins that contains human proteins, namely BCL7A and BCL7B, that are associated with malignant diseases; bcl-7 activity is required for proper terminal seam cell differentiation as well as for normal development of the distal tip cells of the somatic gonad and germ line; in controlling cell development and differentiation, bcl-7 interacts with the Wnt signaling pathway, regulating the asymmetric localization of WRM-1, and hence POP-1, in asymmetric cell divisions; bcl-7 may also function to regulate apoptosis, as loss of bcl-7 activity results in increased expression of ced-9; a BCL-7::GFP reporter is expressed ubiquitously and localized to nuclei; mammalian BCL7 family members are members of Swi/Snf transcriptional regulatory complexes.Paper_evidenceWBPaper00046304
Curator_confirmedWBPerson1843
WBPerson1823
WBPerson567
Date_last_updated20 May 2014 00:00:00
Automated_descriptionPredicted to be involved in Wnt signaling pathway; apoptotic process; and cell differentiation. Predicted to be located in nucleus. Expressed in distal tip cell; germ cell; and gonadal sheath cell. Is an ortholog of human BCL7A (BAF chromatin remodeling complex subunit BCL7A).Paper_evidenceWBPaper00065943
Curator_confirmedWBPerson324
WBPerson37462
Inferred_automaticallyThis description was generated automatically by a script based on data from the WS291 version of WormBase
Date_last_updated29 Nov 2023 00:00:00
Molecular_infoCorresponding_CDSC28H8.1
Corresponding_transcriptC28H8.1.1
Other_sequenceAcan_isotig14735
Oden_isotig13379
CBC13479_1
Tcir_isotig09201
CJC05531_1
Dviv_isotig33085
Tcol_contig20712
Oden_isotig13380
JI180958.1
Associated_featureWBsf645222
WBsf645223
WBsf225029
Experimental_infoRNAi_resultWBRNAi00061740Inferred_automaticallyRNAi_primary
WBRNAi00114621Inferred_automaticallyRNAi_primary
WBRNAi00029301Inferred_automaticallyRNAi_primary
WBRNAi00011309Inferred_automaticallyRNAi_primary
WBRNAi00005962Inferred_automaticallyRNAi_primary
WBRNAi00076175Inferred_automaticallyRNAi_primary
WBRNAi00041425Inferred_automaticallyRNAi_primary
Expr_patternExpr12126
Expr1015868
Expr1036929
Expr1145455
Expr2009584
Expr2027821
Drives_constructWBCnstr00008715
WBCnstr00020228
WBCnstr00020229
WBCnstr00028256
Construct_productWBCnstr00008715
WBCnstr00020228
WBCnstr00020229
WBCnstr00028256
Microarray_resultsSMD_C28H8.1
SMD_C28H8.1:2
187294_at
A_12_P104248
Aff_C28H8.1
GPL13394_WBGene00016192
GPL13914_C28H8.1
GPL14144_C28H8.1_204-263_0.949_3_C
GPL14144_C28H8.1_333-392_0.965_1_A
GPL14144_C28H8.1_4-63_0.651_68_B
GPL19516_CGZ0006501
GPL21109_C28H8.1
GPL3518_CE01820
GPL8304_CE_WBGene00016192_A
GPL8304_CE_WBGene00016192_B
GPL8304_CE_WBGene00016192_C
GPL8673_C28H8_1P00134
GPL8673_C28H8_1P00225
GPL8673_C28H8_1P00322
GPL9450_C28H8.1
cea2.p.58573
Expression_clusterWBPaper00031040:TGF-beta_adult_downregulated
WBPaper00032097:CGH-1-associated-mRNA
WBPaper00033065:isp-1-1(qm150)_upregulated
WBPaper00037950:dopaminergic-neurons_larva_enriched
WBPaper00037950:hypodermis_larva_enriched
WBPaper00037950:PVD-OLL-neurons_larva_enriched
WBPaper00038438:E.faecalis_24hr_downregulated_RNAseq
WBPaper00044426:rotenone_24h_upregulated
WBPaper00044656:tatn-1(qd182)_downregulated
WBPaper00044736:flat_dev_expression
WBPaper00044760:germline_specific
WBPaper00045420:fertilization_downregulated_protein
WBPaper00045521:Oogenic
WBPaper00045729:gld-2(RNAi)_downregulated
WBPaper00046497:B.thuringiensis_0.1mix_downregulated_6h
WBPaper00046887:WNT-target
WBPaper00048762:FOG-3_associated
WBPaper00048923:Aging_regulated
WBPaper00048988:neuron_expressed
WBPaper00049018:SWSN-2.2_interacting
WBPaper00049498:npr-1(ur89)_regulated_3
WBPaper00049545:jmjd-3.1(+)_downregulated
WBPaper00050225:flp-6(RNAi)_downregulated
WBPaper00050488:20C_vs_25C_regulated_mir-34(gk437)_adult
WBPaper00050488:adult_vs_dauer_regulated_N2_20C
WBPaper00050726:OsmoticStress_regulated_Food
WBPaper00050859:downregulated_P-granule(-)GFP(+)_vs_control_day2-adult
WBPaper00050990:arcade_intestinal-valve_expressed
WBPaper00050990:intestine_expressed
WBPaper00050990:pharynx_expressed
WBPaper00051265:F4_morc-1(tm6048)_upregulated
WBPaper00051404:alg-1(gk214)_upregulated
WBPaper00052884:emb-4(hc60)_downregulated
WBPaper00053184:sma-2(rax5)_downregulated
WBPaper00053184:sma-4(rax3)_downregulated
WBPaper00053302:zidovudine_72h_regulated
WBPaper00054493:hpl-2(tm1489)_downregulated
WBPaper00055648:germline_expressed
WBPaper00056034:pals-22(jy3)_downregulated
WBPaper00056090:E.faecalis_downregulated_hpx-2(dg047)
WBPaper00056090:E.faecalis_downregulated_N2
WBPaper00056165:MINA-1_interacting_mRNA
WBPaper00056284:ints-5(RNAi)_downregulated
WBPaper00056826:SGP_biased
WBPaper00057288:Cold_downregulated_transcript
WBPaper00058598:sin-3(tm1276)_upregulated
WBPaper00059664:srbc-48(ac23)_downregulated
WBPaper00059728:5ug_cholesterol_downregulated
WBPaper00059987:Wounding_downregulated
WBPaper00060014:set-2(tm1630)_upregulated
WBPaper00060459:bcat-1(RNAi)_downregulated
WBPaper00060683:hlh-11(ko1)_downregulated
WBPaper00061007:HB101_downregulated
WBPaper00061007:S.aquatilis_downregulated
WBPaper00061045:Y56A3A.22(cck200)_downregulated
WBPaper00061203:sin-3(tm1276)_downregulated
WBPaper00061203:spr-1(ok2144)_downregulated
WBPaper00061274:hypergravity_10xg_upregulated
WBPaper00061341:28C_48h_downregulated
WBPaper00061527:F54E7.8-orc-5_6376
WBPaper00062143:PQN-59_interacting
WBPaper00062159:hda-2(ok1479)_downregulated
WBPaper00062456:doxycycline_downregulated_CB4856_transcript
WBPaper00064005:starvation_upregulated_aptf-1(gk794)_protein
WBPaper00064088:Day-1-adult_vs_L4_downregulated_daf-16(mu86);glp-1(e2141)
WBPaper00064088:Day-3-adult_vs_L4_downregulated_daf-16(mu86);glp-1(e2141)
WBPaper00064088:Day-3-adult_vs_L4_downregulated_glp-1(e2141)
WBPaper00064229:B.thuringiensis-Cry5Ba_downregulated
WBPaper00064502:spe-44(fx110)_upregulated
WBPaper00064716:paraquat_upregulated
WBPaper00065975:P-body_vs_oocyte_enriched
WBPaper00065975:P-body_vs_WholeAnimal_enriched
WBPaper00066038:mip-1(how5)_downregulated
WBPaper00066110:Doxorubicin_downregulated_diploid
WBPaper00066110:tetraploid_vs_diploid_downregulated
WBPaper00066146:germline-inx-14(RNAi)_downregulated_PA14
cgc4386_cluster_6_3
cgc4489_group_5
WBPaper00025141:N2_Expressed_Genes
WBPaper00025141:unc-4::GFP_Expressed_Genes
WBPaper00026929:Resveratrol_regulated_daf-16
WBPaper00026929:sir-2.1_overexpression_regulated
WBPaper00026980:intestine_enriched
WBPaper00030839:Embryo_Pan_Neuronal
WBPaper00031252:AIN-1_IP_enriched
WBPaper00035084:L2_enriched_AIN-2_IP
WBPaper00035588:alg-1(-)_upregulated
WBPaper00035873:dpy-9_regulated
WBPaper00035873:dpy-10_regulated
WBPaper00035905:FBF-1_Associated
WBPaper00036123:Fluoranthene_regulated
WBPaper00036130:mir-243_down_regulated
WBPaper00036286:Pattern_F
WBPaper00037611:RNP-8-associated
WBPaper00037901:GLD-1_mRNA_targets
WBPaper00040210:Diazinon_24C_regulated
WBPaper00040823:alg-1(gk214)_upregulated
WBPaper00040858:eQTL_age_regulated_developing
WBPaper00040858:eQTL_regulated_old
WBPaper00040963:TA300_down
WBPaper00041606:CE_B.thuringiensis-DB27_regulated
WBPaper00041606:CE_X.nematophila_regulated
WBPaper00041906:I-3690_vs_OP50_3d
WBPaper00041939:control_vs_EtBr-exposed_24h
WBPaper00041939:control_vs_EtBr-exposed_48h
WBPaper00041939:control_vs_UVC-EtBr-exposed_48h
WBPaper00041939:UVC-EtBr-exposed_vs_UVC-exposed_48h
WBPaper00045263:0.1mM-paraquat_upregulated
WBPaper00046083:pmk-1(km25)_OP50_upregulated
WBPaper00048989:N2_rapamycin_downregulated
WBPaper00056330:mrps-5(RNAi)_downregulated
[cgc5767]:expression_class_E
[cgc5767]:expression_class_ET
[cgc5767]:expression_class_ET_max(66_min)
[cgc5767]:expression_class_E_pi(53_min)
[cgc5767]:expression_class_E_pi(66_min)
[cgc5767]:expression_class_M
[cgc5767]:expression_class_ME
[cgc5767]:expression_class_MET
[cgc6390]:Cluster_E
[cgc6390]:oogenesis-enriched
Interaction (67)
Map_infoMapIIIPosition-1.43385
PositivePositive_cloneC28H8Inferred_automaticallyFrom sequence, transcript, pseudogene data
Pseudo_map_position
ReferenceWBPaper00032961
WBPaper00038491
WBPaper00046304
WBPaper00055090
RemarkMap position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC.CGC_data_submission
MethodGene