WormBase Tree Display for Gene: WBGene00003768

WBGene00003768 SMap: S_parent: Sequence: B0213
  Identity: Version: 1
    Name: CGC_name: nlp-30 Person_evidence: WBPerson242
      Sequence_name: B0213.5
      Molecular_name: B0213.5
        B0213.5.1
        CE16776
      Other_name: CELE_B0213.5 Accession_evidence: NDB BX284605
      Public_name: nlp-30
    DB_info: Database: AceView gene 5E461
        WormQTL gene WBGene00003768
        WormFlux gene WBGene00003768
        NDB locus_tag CELE_B0213.5
        Panther gene CAEEL|WormBase=WBGene00003768|UniProtKB=O44663
          family PTHR22552
        NCBI gene 3565444
        RefSeq protein NM_071707.4
        SwissProt UniProtAcc O44663
        UniProt_GCRP UniProtAcc O44663
    Species: Caenorhabditis elegans
    History: Version_change: 1 07 Apr 2004 11:29:32 WBPerson1971 Event: Imported: Initial conversion from geneace
    Status: Live
  Gene_info: Biotype: SO:0001217
    Gene_class: nlp
    Allele (26)
    RNASeq_FPKM (74)
    GO_annotation: 00033115
      00033116
      00033117
    Ortholog: WBGene00045436 Caenorhabditis remanei From_analysis: OMA
      WBGene00100569 Pristionchus pacificus From_analysis: OMA
      WBGene00119590 Caenorhabditis japonica From_analysis: OMA
      WBGene00121896 Caenorhabditis japonica From_analysis: OMA
      WBGene00123428 Caenorhabditis japonica From_analysis: OMA
      WBGene00181963 Caenorhabditis japonica From_analysis: OMA
      WBGene00133597 Caenorhabditis japonica From_analysis: OMA
      WBGene00138055 Caenorhabditis japonica From_analysis: OMA
      chrV_pilon.g13882 Caenorhabditis elegans From_analysis: WormBase-Compara
    Paralog (17)
    Structured_description: Concise_description: nlp-30 encodes five predicted neuropeptide-like proteins; in C. elegans, nlp-30 is part of the YGGWamide neuropeptide family that also contains nlp-24, nlp-25, and nlp-27-32; nlp-30 is expressed in the hypodermis, suggesting that the peptides it encodes may have a non-neuronal function; as loss of nlp-30 activity via large-scale RNAi screens does not result in any obvious abnormalities, the precise role of the nlp-30-encoded peptides in development and/or behavior is not yet known. Paper_evidence: WBPaper00004651
            WBPaper00004975
            WBPaper00005654
          Curator_confirmed: WBPerson1843
          Date_last_updated: 17 Jun 2004 00:00:00
      Automated_description: Predicted to be involved in neuropeptide signaling pathway. Predicted to be located in extracellular region. Expressed in hypodermis. Paper_evidence: WBPaper00065943
          Curator_confirmed: WBPerson324
            WBPerson37462
          Inferred_automatically: This description was generated automatically by a script based on data from the WS291 version of WormBase
          Date_last_updated: 29 Nov 2023 00:00:00
  Molecular_info: Corresponding_CDS: B0213.5
    Corresponding_transcript: B0213.5.1
    Other_sequence: TCC02149_1
      CJC03892_1
      TX01802
      PPC12681_1
      PPC01753_1
      CJC09552_1
    Associated_feature: WBsf661202
      WBsf999718
      WBsf1019450
      WBsf231621
  Experimental_info: RNAi_result: WBRNAi00027994 Inferred_automatically: RNAi_primary
      WBRNAi00038738 Inferred_automatically: RNAi_primary
      WBRNAi00009586 Inferred_automatically: RNAi_primary
      WBRNAi00007253 Inferred_automatically: RNAi_primary
    Expr_pattern: Expr1695
      Expr8212
      Expr1142949
      Expr2014295
      Expr2032536
    Drives_construct: WBCnstr00000499
      WBCnstr00006845
      WBCnstr00007224
      WBCnstr00007225
      WBCnstr00007226
      WBCnstr00007227
      WBCnstr00007228
      WBCnstr00007229
      WBCnstr00007230
      WBCnstr00010386
      WBCnstr00013185
      WBCnstr00035880
    Construct_product: WBCnstr00000499
      WBCnstr00035880
    Microarray_results (15)
    Expression_cluster: WBPaper00031040:Cluster_3
      WBPaper00031040:TGF-beta_adult_upregulated
      WBPaper00032031:DConiospora_upregulated_cDNA_12h
      WBPaper00032031:DConiospora_upregulated_cDNA_24h
      WBPaper00032031:DConiospora_upregulated_OligoArray_24h
      WBPaper00032425:down_in_alg-1
      WBPaper00032425:down_in_zfp-1
      WBPaper00033065:cyc-1(RNAi)_upregulated
      WBPaper00033131:dapk-1_upregulated
      WBPaper00037849:sam-10(js94)_upregulated
      WBPaper00038438:D.coniospora_12hr_upregulated_RNAseq
      WBPaper00038438:P.lumniescens_24hr_upregulated_TilingArray
      WBPaper00040209:B.thuringiensis_downregulated_MY15
      WBPaper00043945:MeHg_upregulated
      WBPaper00044736:oscillating_dev_expression
      WBPaper00044760:somatic_specific
      WBPaper00045017:blmp-1(tm548)_upregulated
      WBPaper00045314:S.aureus-induced_hlh-30(tm1978)
      WBPaper00045314:S.aureus-induced_N2
      WBPaper00045316:prg-1_downregulated_L3
      WBPaper00045417:128Q-huntingtin_downreglated
      WBPaper00046795:starvation_upregulated
      WBPaper00049217:DAF-16_downregulated
      WBPaper00049545:cco-1(RNAi)_downregulated
      WBPaper00049732:blmp-1(tm548)_vs_N2_upregulated
      WBPaper00049920:Glucose-Diet_upregulated_N2
      WBPaper00049920:hyl-2(tm2031)_upregulated
      WBPaper00049942:HeatShock_downregulated_hsf-1(RNAi)
      WBPaper00049942:HeatShock_upregulated_hsf-1(+)
      WBPaper00050193:cec-4(ok3124)_upregulated_L1
      WBPaper00050344:AFD-neuron_enriched
      WBPaper00050344:ASER-neuron_enriched
      WBPaper00050344:PLM-neuron_enriched
      WBPaper00050412:cco-1(RNAi)_downregulated_N2
      WBPaper00050488:adult_vs_dauer_regulated_N2_20C
      WBPaper00050488:mir-34(gk437)_vs_mir-34(OverExpression)_regulated_dauer_20C
      WBPaper00050488:N2_vs_mir-34(gk437)_regulated_dauer_20C
      WBPaper00050726:OsmoticStress_regulated_NoFood
      WBPaper00050743:elli-1(sam-3)_downregulated
      WBPaper00050903:mir-35-41(nDf50)_20C_upregulated
      WBPaper00050903:mir-35-41(nDf50)_25C_upregulated
      WBPaper00050990:hypodermis_enriched
      WBPaper00050990:hypodermis_expressed
      WBPaper00051311:VGLN-1-interacting
      WBPaper00052856:Cadmium_regulated
      WBPaper00053023:nrx-1(tm1961);nlg-1(ok259)_upregulated
      WBPaper00053140:IncreasingResponse_20nmAgCit
      WBPaper00053184:sma-2(rax5)_upregulated
      WBPaper00053184:sma-4(rax3)_upregulated
      WBPaper00053295:lin-22(ot267)_upregulated
      WBPaper00053295:lin-22(ot269)_upregulated
      WBPaper00053302:alovudine_24h_regulated
      WBPaper00053302:stavudine_24h_regulated
      WBPaper00053388:dauer_regulated_Cluster5
      WBPaper00053771:up_at_3h-NaCl
      WBPaper00053771:up_at_24h-NaCl
      WBPaper00053771:up_at_dpy-7(e88)
      WBPaper00053810:isp-1(qm150)_downregulated
      WBPaper00053810:nuo-6(qm200)_downregulated
      WBPaper00054191:H3.3(null)_L1_downregulated
      WBPaper00054796:cav-1(RNAi)_downregulated
      WBPaper00055049:S.gordonii_upregulated
      WBPaper00055354:Psora-Allantoin_downregulated
      WBPaper00055354:Psora_downregulated
      WBPaper00055354:Rapamycin-Allantoin_downregulated
      WBPaper00055354:Rapamycin-Metformin_downregulated
      WBPaper00055354:Rifampicin_downregulated
      WBPaper00055626:pry-1(mu38)_downregulated
      WBPaper00055897:heat-shock_upregulated
      WBPaper00055941:atfs-1(et15)_upregulated
      WBPaper00055941:nuo-6(qm200)_downregulated
      WBPaper00055971:nhl-2(ok818)_25C_downregulated
      WBPaper00056090:E.faecalis_upregulated_hpx-2(dg047)
      WBPaper00056090:E.faecalis_upregulated_N2
      WBPaper00056167:Cry5B_downregulated
      WBPaper00056167:ifo-1(kc2)_downregulated
      WBPaper00056169:rrf-3(pk1426)_downregulated_adult
      WBPaper00056169:rrf-3(pk1426)_downregulated_L4
      WBPaper00056169:rrf-3(pk1426)_upregulated_embryo
      WBPaper00056326:zip-3(gk3164)_upregulated_P.aeruginosa-infected
      WBPaper00056443:DietaryRestriction_downregulated
      WBPaper00056471:aak-1(tm1944);aak-2(ok524)_downregulated
      WBPaper00057041:spc-1(cas971)_upregulated
      WBPaper00057041:unc-70(cas983)_upregulated
      WBPaper00057154:HeatShock_upregulated_mRNA
      WBPaper00058598:mex-1(or286)_upregulated
      WBPaper00058598:mex-3(eu149)_upregulated
      WBPaper00058598:sin-3(tm1276)_downregulated
      WBPaper00058725:sftb-1(cer39)_downregulated
      WBPaper00058948:npr-8(ok1439)_downregulated_OP50
      WBPaper00058948:npr-8(ok1439)_downregulated_PA14
      WBPaper00058948:PA14_downregulated
      WBPaper00059117:B.subtilis_upregulated
      WBPaper00059191:hsp-16.2p-LIN-29_downregulated
      WBPaper00059328:mrps-5(RNAi)_downregulated_mRNA
      WBPaper00059421:daf-1(m40)_upregulated
      WBPaper00059421:daf-3(mgDf90)_downregulated
      WBPaper00059537:ngn-1(ok2200)_upregulated
      WBPaper00059605:mut-16(pk710)_upregulated
      WBPaper00059728:5ug_cholesterol_upregulated
      WBPaper00059728:20ug_cholesterol_upregulated
      WBPaper00059739:hira-1(gk835598)_downregulated_L4
      WBPaper00059754:E.faecalis_OG1RF_upregulated
      WBPaper00059824:rnp-6(dh1127)_regulated_S.aureus
      WBPaper00059895:wounding_upregulated
      WBPaper00059987:Wounding_upregulated
      WBPaper00060014:set-2(tm1630)_downregulated
      WBPaper00060358:B.thuringiensis_pathogen_regulated_elt-2(RNAi)
      WBPaper00060399:pqm-1(ok485)_upregulated_CoCl2_6hr
      WBPaper00060445:ikb-1(nr2027)_upregulated_L1
      WBPaper00060445:nfki-1(cer1)_downregulated_L4
      WBPaper00060683:hlh-11(ko1)_upregulated
      WBPaper00060703:nas-38(ok3407)_upregulated
      WBPaper00060811:L1_vs_adult_downregulated_neural
      WBPaper00060871:M.humicola-infection_24h_regulated
      WBPaper00060871:M.humicola-infection_48h_regulated
      WBPaper00060909:atfs-1(et18)_downregulated
      WBPaper00061007:HB101_upregulated
      WBPaper00061007:S.aquatilis_upregulated
      WBPaper00061007:X.citri_upregulated
      WBPaper00061081:E.faecalis_upregulated_N2
      WBPaper00061081:E.faecalis_upregulated_skpo-1(ok1640)
      WBPaper00061203:sin-3(tm1276)_upregulated
      WBPaper00061203:spr-1(ok2144)_upregulated
      WBPaper00061340:Hypodermis
      WBPaper00061390:N2_ascarosides_downregulated
      WBPaper00061424:Diet_MYb120_upregulated
      WBPaper00061424:Diet_MYb131_upregulated
      WBPaper00061527:ZK970.7-nlp-29
      WBPaper00061530:nhr-49(e2144)_upregulated
      WBPaper00061590:CGP37157_downregulated
      WBPaper00061613:human-amyloid-beta_alpha-Synuclein(A53T)_upregulated
      WBPaper00061853:osm-3(dh441)_downregulated
      WBPaper00061853:osm-3(dh441)_downregulated_tunicamycin
      WBPaper00061952:daf-18(nr2037)_upregulated
      WBPaper00062078:NMR-HspB1_regulated
      WBPaper00062156:jmjd-1.2(zr1010)_upregulated
      WBPaper00062156:jmjd-5(zr1234)_upregulated
      WBPaper00062159:hda-2(ok1479)_upregulated
      WBPaper00062193:skn-1(RNAi)_upregulated
      WBPaper00062325:muscle_depleted_coding-RNA
      WBPaper00062345:bortezomib_4h_upregulated_zip-1(jy13)
      WBPaper00062347:blmp-1(tm548)_upregulated
      WBPaper00062354:H.zoospora_6h_regulated
      WBPaper00062354:H.zoospora_12h_regulated
      WBPaper00062446:nhr-8(hd117)_upregulated
      WBPaper00062456:doxycycline_upregulated_N2_transcript
      WBPaper00062534:fat-P-80_downregulated
      WBPaper00062585:hlh-26(ok1453)_upregulated_E.faecium
      WBPaper00062590:Aging_downregulated_neuron
      WBPaper00062672:let-418(n3536)dcp-66(RNAi)_upregulated
      WBPaper00062672:let-418(n3536)_upregulated
      WBPaper00062715:blmp-1(s71)_upregulated
      WBPaper00064005:starvation_downregulated_aptf-1(gk794)_mRNA
      WBPaper00064005:starvation_downregulated_N2_mRNA
      WBPaper00064088:Day-1-adult_vs_L4_downregulated_daf-16(mu86);glp-1(e2141)
      WBPaper00064088:Day-1-adult_vs_L4_downregulated_fem-3(q20)
      WBPaper00064088:Day-1-adult_vs_L4_downregulated_glp-1(e2141)
      WBPaper00064088:Day-3-adult_vs_L4_downregulated_daf-16(mu86);glp-1(e2141)
      WBPaper00064088:Day-3-adult_vs_L4_downregulated_fem-3(q20)
      WBPaper00064088:Day-3-adult_vs_L4_downregulated_glp-1(e2141)
      WBPaper00064403:Heat-killed-E.Coli_upregulated
      WBPaper00065005:sams-4(RNAi)_upregulated
      WBPaper00065074:glna(-)_downregulated
      WBPaper00065096:25C_vs_20C_downregulated
      WBPaper00065096:Day10_vs_Day1_downregulated
      WBPaper00065096:npr-8(ok1439)_upregulated_Day1_25C
      WBPaper00065158:25C_vs_15C_downregulated_WholeAnimal
      WBPaper00065581:hpk-1(pk1393)_upregulated
      WBPaper00065749:Heat-Shock_downregulated_N2
      WBPaper00065823:pmk-1(km25)_downregulated
      WBPaper00065835:Day5_vs_Day1_downregulated
      WBPaper00065835:Day11_vs_Day1_downregulated
      WBPaper00065841:2_0
      WBPaper00065841:82_0
      WBPaper00065975:P-body_vs_oocyte_depleted
      WBPaper00066004:tdp-1(csb38)_upregulated
      WBPaper00066110:tetraploid_vs_diploid_upregulated
      WBPaper00066204:CdCl2_upregulated_mRNA
      WBPaper00066232:ash-2(RNAi)_downregulated_WT
      cgc4386_cluster_3_4
      cgc4489_group_12
      WBPaper00005124:progesterone_10-7M_regulated
      WBPaper00025141:N2_Expressed_Genes
      WBPaper00025141:unc-4::GFP_Expressed_Genes
      WBPaper00026952:class_E
      WBPaper00026980:intestine_enriched
      WBPaper00028474:dys-1_downregulated
      WBPaper00028789:PA14_vs_OP50_upregulated_4hr
      WBPaper00028789:pmk-1_upregulated
      WBPaper00029437:dcr-1_upregulated
      WBPaper00031003:0hr_muscle_depleted
      WBPaper00031003:24hr_muscle_depleted
      WBPaper00031003:total_muscle_depleted
      WBPaper00031532:Larva_Pan_Neuronal_Depleted
      WBPaper00032948:FedUp
      WBPaper00034661:AgNPs_upregulated
      WBPaper00034757:up_by_oxidative_stress
      WBPaper00035560:ahr-1_downregulated
      WBPaper00035873:dpy-9_regulated
      WBPaper00035873:dpy-10_regulated
      WBPaper00035873:osm-7_regulated
      WBPaper00035873:osm-8_regulated
      WBPaper00035873:osm-11_regulated
      WBPaper00035873:osmotically_regulated
      WBPaper00036130:mir-243_up_regulated
      WBPaper00036286:Pattern_G
      WBPaper00036464:S.aureus-RN6390_regulated
      WBPaper00037695:CC_3-day
      WBPaper00038172:crh-1null_up_regulated
      WBPaper00038172:tax-6null_up_regulated
      WBPaper00038304:octr-1_regulated
      WBPaper00040426:CYD-1_CDK-4_upregulated
      WBPaper00040603:tdp-1(lf)_up_vs_N2_FC_1.2
      WBPaper00040603:tdp-1(lf)_up_vs_N2_FC_1.5
      WBPaper00040823:alg-1(gk214)_upregulated
      WBPaper00040858:eQTL_age_regulated_developing
      WBPaper00040858:eQTL_regulated_developing
      WBPaper00040963:Q100_up
      WBPaper00040963:Q200_up
      WBPaper00040963:TA100_up
      WBPaper00040963:TA200_up
      WBPaper00040963:TA300_up
      WBPaper00041002:HF_3d_0.2mM_Up
      WBPaper00041002:HF_3d_2.0mM_Up
      WBPaper00041002:HF_11d_2.0mM_Down
      WBPaper00041002:HQ_3d_2.0mM_Up
      WBPaper00041207:CE_dauer_down
      WBPaper00041606:CE_B.thuringiensis-DB27_regulated
      WBPaper00041606:CE_S.marcescens_regulated
      WBPaper00041606:CE_X.nematophila_regulated
      WBPaper00041939:control_vs_UVC-EtBr-exposed_48h
      WBPaper00041939:UVC-EtBr-exposed_vs_UVC-exposed_48h
      WBPaper00041939:UVC-EtBr-exposed_vs_UVC-exposed_51h
      WBPaper00041960:N2_fasting_upregulated_anytime
      WBPaper00042067:Cu2+_upregulated_WT
      WBPaper00042128:gei-8(ok1671)_upregulated
      WBPaper00042178:hlh-29(tm284)_upregulated
      WBPaper00042258:DA1877_upregulated_GravidAdult
      WBPaper00042274:tbx-2(bx59)_upregulated
      WBPaper00042574:N2_OrsayVirus_downregulated
      WBPaper00044091:Bpseudomallei_induced_2h
      WBPaper00044091:Bpseudomallei_induced_8h
      WBPaper00044091:Bpseudomallei_induced_12h
      WBPaper00044535:male_upregulated
      WBPaper00045015:acs-3(ft5)_upregulated
      WBPaper00045015:nhr-25(RNAi)_upregulated
      WBPaper00045263:0.1mM-paraquat_downregulated
      WBPaper00045673:colistin_upregulated
      WBPaper00045960:L4-lethargus_upregulated
      WBPaper00046083:pmk-1(km25)_OP50_downregulated
      WBPaper00047070:N2_starvation_downregulated
      WBPaper00047070:xpa-1_UV_upregulated
      WBPaper00048989:N2_allantoin_downregulated
      WBPaper00050515:nipi-3(fr4)_upregulated
      WBPaper00050515:pmk-1(km25)_downregulated
      WBPaper00051448:P.aeruginosa_Slow-Killing_upregulated
      WBPaper00053236:Starvation_regulated_GR1307
      WBPaper00053236:Starvation_regulated_N2
      WBPaper00053550:daf-19(m86)_downregulated_L1
      WBPaper00053827:pyoverdine_upregulated
      WBPaper00057098:SiO2-nanoparticles_downregulated
    Interaction: WBInteraction000136561
      WBInteraction000141781
      WBInteraction000190627
      WBInteraction000382206
      WBInteraction000419747
      WBInteraction000518416
      WBInteraction000561538
  Map_info: Map: V Position: -7.3412 Error: 0.001619
    Positive: Positive_clone: B0213 Inferred_automatically: From CDS info
            From sequence, transcript, pseudogene data
    Pseudo_map_position
  Reference: WBPaper00004975
    WBPaper00006488
    WBPaper00032031
    WBPaper00033777
    WBPaper00050183
    WBPaper00055020
    WBPaper00060703
    WBPaper00062715
    WBPaper00063691
  Remark: Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. CGC_data_submission
  Method: Gene