WormBase Tree Display for Gene: WBGene00015735
expand all nodes | collapse all nodes | view schema
WBGene00015735 | SMap | S_parent | Sequence | C13B9 | |||||
---|---|---|---|---|---|---|---|---|---|
Identity | Version | 3 | |||||||
Name | CGC_name | pdfr-1 | Paper_evidence | WBPaper00031656 | |||||
Person_evidence | WBPerson3516 | ||||||||
WBPerson3480 | |||||||||
Sequence_name | C13B9.4 | ||||||||
Molecular_name (23) | |||||||||
Other_name | seb-1 | Person_evidence | WBPerson3006 | ||||||
WBPerson1263 | |||||||||
CELE_C13B9.4 | Accession_evidence | NDB | BX284603 | ||||||
Public_name | pdfr-1 | ||||||||
DB_info | Database | AceView | gene | 3H724 | |||||
WormQTL | gene | WBGene00015735 | |||||||
WormFlux | gene | WBGene00015735 | |||||||
NDB | locus_tag | CELE_C13B9.4 | |||||||
Panther | gene | CAEEL|WormBase=WBGene00015735|UniProtKB=Q09460 | |||||||
family | PTHR45620 | ||||||||
NCBI | gene | 175942 | |||||||
RefSeq | protein | NM_001372610.3 | |||||||
NM_001382898.2 | |||||||||
NM_001026000.5 | |||||||||
NM_001025999.5 | |||||||||
NM_001306692.3 | |||||||||
SwissProt | UniProtAcc | Q09460 | |||||||
TrEMBL | UniProtAcc | S6F595 | |||||||
S6FD44 | |||||||||
UniProt_GCRP | UniProtAcc | Q09460 | |||||||
OMIM | gene | 114131 | |||||||
114190 | |||||||||
168468 | |||||||||
Species | Caenorhabditis elegans | ||||||||
History | Version_change | 1 | 28 May 2004 13:30:56 | WBPerson1971 | Event | Imported | Initial conversion from CDS class of stlace from WS125 | ||
2 | 18 Apr 2008 13:26:44 | WBPerson2970 | Name_change | CGC_name | pdfr-1 | ||||
3 | 29 Aug 2012 16:49:31 | WBPerson2970 | Name_change | Other_name | seb-1 | ||||
Status | Live | ||||||||
Gene_info | Biotype | SO:0001217 | |||||||
Gene_class | pdfr | ||||||||
Allele (246) | |||||||||
Strain (11) | |||||||||
RNASeq_FPKM (74) | |||||||||
GO_annotation (31) | |||||||||
Ortholog (47) | |||||||||
Paralog | WBGene00007664 | Caenorhabditis elegans | From_analysis | TreeFam | |||||
Panther | |||||||||
WormBase-Compara | |||||||||
WBGene00014035 | Caenorhabditis elegans | From_analysis | Panther | ||||||
WormBase-Compara | |||||||||
WBGene00002251 | Caenorhabditis elegans | From_analysis | WormBase-Compara | ||||||
WBGene00002252 | Caenorhabditis elegans | From_analysis | WormBase-Compara | ||||||
WBGene00009304 | Caenorhabditis elegans | From_analysis | WormBase-Compara | ||||||
WBGene00017947 | Caenorhabditis elegans | From_analysis | WormBase-Compara | ||||||
WBGene00017948 | Caenorhabditis elegans | From_analysis | WormBase-Compara | ||||||
Structured_description | Concise_description | pdfr-1 encodes, by alternative splicing, three isoforms of a G-protein-coupled receptor (GPCR) required for normal locomotion; PDFR-1 is orthologous to Drosophila pigment dispersing factor (PDF) receptors, and to human CALCR (OMIM:114131, associated with susceptibility to osteoporesis); pdfr-1 is expressed in all body wall muscles and many head and tail neurons; the C. elegans neuropeptides PDF-1a, PDF-1b, or PDF-2 (orthologous to Drosophila PDF) activated PDFR-1 receptors with dose-dependent nanomolar potency; in vivo, excess PDF-2 induces a movement phenotype like that seen in a pdf-1 null mutant, indicating that PDF-1a/b and PDF-2 exert opposite effects on PDFR-1. | Paper_evidence | WBPaper00012979 | |||||
WBPaper00028902 | |||||||||
WBPaper00031656 | |||||||||
Curator_confirmed | WBPerson1843 | ||||||||
WBPerson1823 | |||||||||
WBPerson567 | |||||||||
Date_last_updated | 14 Jul 2008 00:00:00 | ||||||||
Automated_description | Enables calcitonin family receptor activity. Involved in several processes, including locomotory behavior; signal transduction; and sleep. Located in plasma membrane. Expressed in several structures, including I1 neuron; RMEV; ganglia; mechanosensory neurons; and vulD. Human ortholog(s) of this gene implicated in bone disease (multiple); hereditary lymphedema; and primary failure of tooth eruption. Is an ortholog of human CALCR (calcitonin receptor); CALCRL (calcitonin receptor like receptor); and PTH1R (parathyroid hormone 1 receptor). | Paper_evidence | WBPaper00065943 | ||||||
Curator_confirmed | WBPerson324 | ||||||||
WBPerson37462 | |||||||||
Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||||
Date_last_updated | 29 Nov 2023 00:00:00 | ||||||||
Disease_info | Potential_model (7) | ||||||||
Molecular_info | Corresponding_CDS | C13B9.4a | |||||||
C13B9.4b | |||||||||
C13B9.4c | |||||||||
C13B9.4d | |||||||||
C13B9.4e | |||||||||
Corresponding_CDS_history | C13B9.4:wp127 | ||||||||
Corresponding_transcript (13) | |||||||||
Other_sequence (25) | |||||||||
Associated_feature (24) | |||||||||
Experimental_info | RNAi_result | WBRNAi00010677 | Inferred_automatically | RNAi_primary | |||||
WBRNAi00005367 | Inferred_automatically | RNAi_primary | |||||||
WBRNAi00027171 | Inferred_automatically | RNAi_primary | |||||||
WBRNAi00040427 | Inferred_automatically | RNAi_primary | |||||||
WBRNAi00024543 | Inferred_automatically | RNAi_primary | |||||||
WBRNAi00024544 | Inferred_automatically | RNAi_primary | |||||||
WBRNAi00028838 | Inferred_automatically | RNAi_primary | |||||||
Expr_pattern (15) | |||||||||
Drives_construct | WBCnstr00002179 | ||||||||
WBCnstr00002180 | |||||||||
WBCnstr00004248 | |||||||||
WBCnstr00004988 | |||||||||
WBCnstr00015834 | |||||||||
WBCnstr00015836 | |||||||||
WBCnstr00019100 | |||||||||
WBCnstr00021690 | |||||||||
WBCnstr00021702 | |||||||||
WBCnstr00028610 | |||||||||
Construct_product (12) | |||||||||
Antibody | WBAntibody00001399 | ||||||||
Microarray_results (36) | |||||||||
Expression_cluster (224) | |||||||||
Interaction (12) | |||||||||
Map_info | Map | III | Position | -1.02511 | Error | 0.00506 | |||
Positive | Positive_clone | C13B9 | Inferred_automatically | From sequence, transcript, pseudogene data | |||||
Pseudo_map_position | |||||||||
Reference (36) | |||||||||
Remark | Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | |||||||
Method | Gene |