WormBase Tree Display for Gene: WBGene00009304
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WBGene00009304 | SMap | S_parent | Sequence | F32A7 | |||||
---|---|---|---|---|---|---|---|---|---|
Identity | Version | 3 | |||||||
Name | CGC_name | eva-1 | Paper_evidence | WBPaper00031043 | |||||
Person_evidence | WBPerson2189 | ||||||||
WBPerson893 | |||||||||
Sequence_name | F32A7.3 | ||||||||
Molecular_name (12) | |||||||||
Other_name | tag-271 | ||||||||
CELE_F32A7.3 | Accession_evidence | NDB | BX284601 | ||||||
Public_name | eva-1 | ||||||||
DB_info | Database (11) | ||||||||
Species | Caenorhabditis elegans | ||||||||
History | Version_change | 1 | 26 May 2004 16:54:50 | WBPerson1971 | Event | Imported | Initial conversion from CDS class of WS125 | ||
2 | 22 Apr 2005 11:55:18 | WBPerson2970 | Name_change | CGC_name | tag-271 | ||||
3 | 09 Oct 2007 15:40:26 | WBPerson2970 | Name_change | CGC_name | eva-1 | ||||
Other_name | tag-271 | ||||||||
Status | Live | ||||||||
Gene_info | Biotype | SO:0001217 | |||||||
Gene_class | eva | ||||||||
Allele (99) | |||||||||
Strain | WBStrain00036134 | ||||||||
WBStrain00054912 | |||||||||
RNASeq_FPKM (74) | |||||||||
GO_annotation | 00002163 | ||||||||
00101597 | |||||||||
00101598 | |||||||||
00101599 | |||||||||
00101600 | |||||||||
00101601 | |||||||||
00101602 | |||||||||
00117029 | |||||||||
Ortholog (33) | |||||||||
Paralog | WBGene00002251 | Caenorhabditis elegans | From_analysis | WormBase-Compara | |||||
WBGene00002252 | Caenorhabditis elegans | From_analysis | WormBase-Compara | ||||||
WBGene00007664 | Caenorhabditis elegans | From_analysis | WormBase-Compara | ||||||
WBGene00014035 | Caenorhabditis elegans | From_analysis | WormBase-Compara | ||||||
WBGene00015735 | Caenorhabditis elegans | From_analysis | WormBase-Compara | ||||||
WBGene00017947 | Caenorhabditis elegans | From_analysis | WormBase-Compara | ||||||
WBGene00017948 | Caenorhabditis elegans | From_analysis | WormBase-Compara | ||||||
Structured_description | Concise_description | eva-1 encodes, by alternative splicing, two isoforms of a cell-surface protein that acts cell-autonomously with SAX-3 as a SLT-1 receptor subunit, and is required for guidance of the AVM pioneer axon to the ventral nerve cord; EVA-1's long isoform is predicted to have a signal sequence, an ectodomain with two lectinlike galactose-binding sequences, a single transmembrane sequence, and a cytodomain with a phosphotyrosine binding motif; homologs of EVA-1 include human C21orf63; EVA-1 is expressed in embryonic neurons during axonal growth, head and tail neurons, the ventral nerve cord, pharyngeal and body wall muscles, hypodermis, uterus and vulva; ectopic EVA-1 expression in touch-receptor neurons causes the cell body of ALM to be displaced anteriorly (due to failed posterior migration) in a SLT-1-dependent manner; the cytodomain of EVA-1 is functionally dispensable in vivo; eva-1 mutants enhance the ventral-axon guidance defects of unc-40 mutants; EVA-1, SLT-1, and SAX-3 bind one another in vitro. | Paper_evidence | WBPaper00031043 | |||||
Curator_confirmed | WBPerson567 | ||||||||
Date_last_updated | 29 Dec 2007 00:00:00 | ||||||||
Automated_description | Predicted to enable carbohydrate binding activity. Located in M band; cell junction; and striated muscle dense body. Expressed in body wall musculature; hypodermis; pharyngeal muscle cell; and ventral nerve cord. Is an ortholog of human EVA1C (eva-1 homolog C). | Paper_evidence | WBPaper00065943 | ||||||
Curator_confirmed | WBPerson324 | ||||||||
WBPerson37462 | |||||||||
Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||||
Date_last_updated | 29 Nov 2023 00:00:00 | ||||||||
Molecular_info | Corresponding_CDS | F32A7.3a | |||||||
F32A7.3b | |||||||||
F32A7.3c | |||||||||
Corresponding_CDS_history | F32A7.3a:wp114 | ||||||||
F32A7.3b:wp114 | |||||||||
Corresponding_transcript | F32A7.3a.1 | ||||||||
F32A7.3b.1 | |||||||||
F32A7.3b.2 | |||||||||
F32A7.3b.3 | |||||||||
F32A7.3b.4 | |||||||||
F32A7.3c.1 | |||||||||
Other_sequence | Oden_isotig19651 | ||||||||
FD514519.1 | |||||||||
CJC06290_1 | |||||||||
CRC10951_1 | |||||||||
CBC04911_1 | |||||||||
CSC00310_1 | |||||||||
Associated_feature (13) | |||||||||
Experimental_info | RNAi_result | WBRNAi00109732 | Inferred_automatically | RNAi_primary | |||||
WBRNAi00066624 | Inferred_automatically | RNAi_primary | |||||||
WBRNAi00046088 | Inferred_automatically | RNAi_primary | |||||||
WBRNAi00109779 | Inferred_automatically | RNAi_primary | |||||||
WBRNAi00109638 | Inferred_automatically | RNAi_primary | |||||||
WBRNAi00101830 | Inferred_automatically | RNAi_primary | |||||||
WBRNAi00031650 | Inferred_automatically | RNAi_primary | |||||||
WBRNAi00116608 | Inferred_automatically | RNAi_primary | |||||||
WBRNAi00003551 | Inferred_automatically | RNAi_primary | |||||||
WBRNAi00109685 | Inferred_automatically | RNAi_primary | |||||||
Expr_pattern | Expr4895 | ||||||||
Expr9367 | |||||||||
Expr1015991 | |||||||||
Expr1034065 | |||||||||
Expr1149975 | |||||||||
Expr2011386 | |||||||||
Expr2029622 | |||||||||
Drives_construct | WBCnstr00012316 | ||||||||
WBCnstr00019877 | |||||||||
WBCnstr00032298 | |||||||||
Construct_product | WBCnstr00012316 | ||||||||
WBCnstr00013932 | |||||||||
WBCnstr00019586 | |||||||||
WBCnstr00019593 | |||||||||
WBCnstr00019594 | |||||||||
WBCnstr00032298 | |||||||||
Antibody | WBAntibody00001309 | ||||||||
Microarray_results (30) | |||||||||
Expression_cluster (229) | |||||||||
Interaction | WBInteraction000028967 | ||||||||
WBInteraction000262189 | |||||||||
WBInteraction000524192 | |||||||||
WBInteraction000543558 | |||||||||
WBInteraction000551356 | |||||||||
WBInteraction000551357 | |||||||||
WBInteraction000551359 | |||||||||
WBInteraction000555696 | |||||||||
WBInteraction000555697 | |||||||||
WBInteraction000555698 | |||||||||
Map_info | Map | I | Position | 27.9483 | Error | 0.004097 | |||
Positive | Positive_clone | F32A7 | Inferred_automatically | From sequence, transcript, pseudogene data | |||||
Mapping_data | Multi_point | 5192 | |||||||
Pseudo_map_position | |||||||||
Reference (15) | |||||||||
Remark | Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | |||||||
Method | Gene |