WormBase Tree Display for Gene: WBGene00004749
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WBGene00004749 | SMap | S_parent | Sequence | F57C7 | |||||
---|---|---|---|---|---|---|---|---|---|
Identity | Version | 1 | |||||||
Name | CGC_name | sdn-1 | Person_evidence | WBPerson1831 | |||||
Sequence_name | F57C7.3 | ||||||||
Molecular_name | F57C7.3a | ||||||||
F57C7.3a.1 | |||||||||
CE05996 | |||||||||
F57C7.3b | |||||||||
CE32681 | |||||||||
F57C7.3b.1 | |||||||||
Other_name | CELE_F57C7.3 | Accession_evidence | NDB | BX284606 | |||||
Public_name | sdn-1 | ||||||||
DB_info | Database | AceView | gene | XL210 | |||||
WormQTL | gene | WBGene00004749 | |||||||
WormFlux | gene | WBGene00004749 | |||||||
NDB | locus_tag | CELE_F57C7.3 | |||||||
Panther | gene | CAEEL|WormBase=WBGene00004749|UniProtKB=P50605 | |||||||
family | PTHR10915 | ||||||||
NCBI | gene | 181259 | |||||||
RefSeq | protein | NM_171769.7 | |||||||
NM_171972.7 | |||||||||
SwissProt | UniProtAcc | P50605 | |||||||
TREEFAM | TREEFAM_ID | TF320463 | |||||||
TrEMBL | UniProtAcc | Q8I4H9 | |||||||
UniProt_GCRP | UniProtAcc | P50605 | |||||||
Species | Caenorhabditis elegans | ||||||||
History | Version_change | 1 | 07 Apr 2004 11:29:36 | WBPerson1971 | Event | Imported | Initial conversion from geneace | ||
Status | Live | ||||||||
Gene_info | Biotype | SO:0001217 | |||||||
Gene_class | sdn | ||||||||
Allele (60) | |||||||||
Strain | WBStrain00031428 | ||||||||
WBStrain00000144 | |||||||||
WBStrain00050774 | |||||||||
RNASeq_FPKM (74) | |||||||||
GO_annotation (19) | |||||||||
Ortholog (42) | |||||||||
Structured_description | Concise_description | sdn-1 encodes a homolog of vertebrate syndecan-2, a type I transmembrane heparan sulfate proteoglycan; by homology, SDN-1 is predicted to play a role in cell-cell and cell-matrix adhesion; loss of sdn-1 activity via RNA-mediated interference (RNAi) indicates that SDN-1 is required for backward locomotion and for normal development of the egg-laying system, particularly gonadal and vulval structures; SDN-1 is expressed in a subset of neuronal cell bodies and their associated processes in the nerve ring, and also in select tail neurons. | Paper_evidence | WBPaper00011289 | |||||
WBPaper00018603 | |||||||||
Curator_confirmed | WBPerson1843 | ||||||||
Date_last_updated | 17 Jun 2004 00:00:00 | ||||||||
Automated_description | Involved in embryo development; epidermis morphogenesis; and nematode larval development. Located in cell surface. Expressed in several structures, including neuroblasts; neurons; pharynx; somatic nervous system; and vulva. Human ortholog(s) of this gene implicated in several diseases, including Hodgkin's lymphoma; cleft lip; and glucose metabolism disease (multiple). Is an ortholog of human SDC1 (syndecan 1); SDC2 (syndecan 2); and SDC4 (syndecan 4). | Paper_evidence | WBPaper00065943 | ||||||
Curator_confirmed | WBPerson324 | ||||||||
WBPerson37462 | |||||||||
Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||||
Date_last_updated | 29 Nov 2023 00:00:00 | ||||||||
Disease_info | Potential_model | DOID:9296 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:10659) | ||||
DOID:8567 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:10658) | ||||||
DOID:4195 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:10658) | ||||||
DOID:3910 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:10658) | ||||||
DOID:9352 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:10659) | ||||||
DOID:5844 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:10661) | ||||||
DOID:674 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:10659) | ||||||
Molecular_info | Corresponding_CDS | F57C7.3a | |||||||
F57C7.3b | |||||||||
Corresponding_CDS_history | F57C7.3:wp83 | ||||||||
Corresponding_transcript | F57C7.3a.1 | ||||||||
F57C7.3b.1 | |||||||||
Other_sequence (22) | |||||||||
Associated_feature (27) | |||||||||
Experimental_info | RNAi_result (9) | ||||||||
Expr_pattern (12) | |||||||||
Drives_construct | WBCnstr00000700 | ||||||||
WBCnstr00001405 | |||||||||
WBCnstr00001406 | |||||||||
WBCnstr00019775 | |||||||||
WBCnstr00020032 | |||||||||
WBCnstr00035413 | |||||||||
Construct_product (13) | |||||||||
Antibody | WBAntibody00000804 | ||||||||
WBAntibody00002534 | |||||||||
Microarray_results (26) | |||||||||
Expression_cluster (124) | |||||||||
Interaction (34) | |||||||||
Anatomy_function | WBbtf0790 | ||||||||
WBbtf0791 | |||||||||
WBbtf0792 | |||||||||
Map_info | Map | X | Position | 2.31221 | Error | 0.009839 | |||
Positive | Positive_clone | F57C7 | Inferred_automatically | From CDS info | |||||
From sequence, transcript, pseudogene data | |||||||||
Mapping_data | Multi_point | 4532 | |||||||
4652 | |||||||||
4134 | |||||||||
Pseudo_map_position | |||||||||
Reference (47) | |||||||||
Remark | Sequence connection from [Turnbull J, Kinnunen T]. krb 13/11/01 | ||||||||
Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | ||||||||
Method | Gene |