WormBase Tree Display for Gene: WBGene00002344

WBGene00002344 SMap: S_parent: Sequence: M7
  Identity: Version: 1
    Name: CGC_name: let-70 Person_evidence: WBPerson533
      Sequence_name: M7.1
      Molecular_name: M7.1
        M7.1.1
        CE03482
      Other_name: ubc-2
        CELE_M7.1 Accession_evidence: NDB BX284604
      Public_name: let-70
    DB_info: Database: AceView gene 4L846
        WormQTL gene WBGene00002344
        WormFlux gene WBGene00002344
        NDB locus_tag CELE_M7.1
        Panther gene CAEEL|WormBase=WBGene00002344|UniProtKB=P35129
          family PTHR24068
        NCBI gene 178006
        RefSeq protein NM_069664.7
        KEGG KEGG_id 2.3.2.23
        NemaPath KEGG_id 2.3.2.23
        SwissProt UniProtAcc P35129
        UniProt_GCRP UniProtAcc P35129
    Species: Caenorhabditis elegans
    History: Version_change: 1 07 Apr 2004 11:29:27 WBPerson1971 Event: Imported: Initial conversion from geneace
    Status: Live
  Gene_info (12)
  Molecular_info: Corresponding_CDS: M7.1
    Corresponding_transcript: M7.1.1
    Other_sequence (191)
    Associated_feature: WBsf668290
      WBsf997760
      WBsf1018171
      WBsf230817
      WBsf230818
  Experimental_info: RNAi_result (45)
    Expr_pattern: Expr725
      Expr726
      Expr1511
      Expr3635
      Expr12883
      Expr1021868
      Expr1031350
      Expr1154754
      Expr2013070
      Expr2031302
    Drives_construct: WBCnstr00001832
      WBCnstr00012506
      WBCnstr00022714
      WBCnstr00022715
      WBCnstr00022808
      WBCnstr00023038
      WBCnstr00036331
    Construct_product: WBCnstr00001832
      WBCnstr00011560
      WBCnstr00012506
      WBCnstr00022714
      WBCnstr00036331
    Antibody: WBAntibody00000112
    Microarray_results (21)
    Expression_cluster: WBPaper00031040:TGF-beta_adult_downregulated
      WBPaper00032097:CGH-1-associated-mRNA
      WBPaper00032528:L3_enriched
      WBPaper00036662:oxidative_modification
      WBPaper00037682:sma-2_upregulated
      WBPaper00037950:A-class-motor-neurons_L1-larva_expressed
      WBPaper00037950:A-class-motor-neurons_L2-larva_expressed
      WBPaper00037950:all-neurons_L1-larva_expressed
      WBPaper00037950:all-neurons_L2-larva_expressed
      WBPaper00037950:AVA-neuron_L1-larva_expressed
      WBPaper00037950:AVE-neuron_L1-larva_expressed
      WBPaper00037950:BAG-neuron_blastula-embryo_expressed
      WBPaper00037950:bodywall-muscle_L1-larva_expressed
      WBPaper00037950:bodywall-muscle_L2-larva_expressed
      WBPaper00037950:coelomocytes_L1-larva_expressed
      WBPaper00037950:coelomocytes_L2-larva_expressed
      WBPaper00037950:dopaminergic-neurons_L3-L4-larva_expressed
      WBPaper00037950:GABAergic-motor-neurons_L1-larva_expressed
      WBPaper00037950:germline-precursors_blastula-embryo_expressed
      WBPaper00037950:glr-1(+)-neurons_L2-larva_expressed
      WBPaper00037950:hypodermis_L1-larva_expressed
      WBPaper00037950:intestine_L1-larva_expressed
      WBPaper00037950:pharyngeal-muscle_L1-larva_expressed
      WBPaper00038061:aldicarb_upregulated
      WBPaper00038118:aak-2(gt33)_upregulated
      WBPaper00040221:DAF-12_target_ALF9
      WBPaper00044736:flat_dev_expression
      WBPaper00044786:emr-1(RNAi);lem-2(tm1582)_downregulated
      WBPaper00045420:fertilization_downregulated_transcript
      WBPaper00045521:Gender_Neutral
      WBPaper00048988:daf-2(e1370)_daf-16(mu86)_upregulated_neuron
      WBPaper00048988:neuron_expressed
      WBPaper00049545:cco-1(RNAi)_upregulated
      WBPaper00050344:PLM-neuron_enriched
      WBPaper00050468:hlh-30-dependent_Cry5B_regulated
      WBPaper00050488:20C_vs_25C_regulated_N2_adult
      WBPaper00050488:adult_vs_dauer_regulated_N2_20C
      WBPaper00050488:mir-34(gk437)_vs_mir-34(OverExpression)_regulated_dauer_20C
      WBPaper00050686:glp-1(e2141)_downregulated
      WBPaper00050698:DEP-1_interacting
      WBPaper00050990:arcade_intestinal-valve_expressed
      WBPaper00050990:body-muscle_expressed
      WBPaper00050990:GABAergic-neuron_expressed
      WBPaper00050990:hypodermis_expressed
      WBPaper00050990:intestine_expressed
      WBPaper00050990:NMDA-neuron_expressed
      WBPaper00050990:pharynx_expressed
      WBPaper00050990:seam_expressed
      WBPaper00051039:germline_enriched
      WBPaper00051245:body-wall-muscle_cytoplasm_expressed
      WBPaper00051245:body-wall-muscle_nucleus_expressed
      WBPaper00051245:epidermis_cytoplasm_expressed
      WBPaper00051245:epidermis_nucleus_expressed
      WBPaper00051245:intestine_cytoplasm_expressed
      WBPaper00051245:intestine_nucleus_expressed
      WBPaper00051245:pharyngeal-muscle_cytoplasm_expressed
      WBPaper00053184:sma-2(rax5)_downregulated
      WBPaper00053184:sma-4(rax3)_downregulated
      WBPaper00053302:zidovudine_72h_regulated
      WBPaper00053814:25C_downregulated_OP50
      WBPaper00053814:25C_downregulated_PY79
      WBPaper00055648:germline_expressed
      WBPaper00056090:E.faecalis_downregulated_hpx-2(dg047)
      WBPaper00056900:TOFU-6_interacting
      WBPaper00057288:Cold_downregulated_protein
      WBPaper00057288:iff-1(RNAi)_downregulated_transcript
      WBPaper00058691:sin-3(tm1276)_upregulated
      WBPaper00059174:MEG-3_interacting
      WBPaper00059328:mrps-5(RNAi)_downregulated_protein
      WBPaper00059440:LAG-1_activated_4hr-auxin
      WBPaper00059471:EGL-43_interacting
      WBPaper00059763:neuron_expressed
      WBPaper00060661:sensory-neuron_enriched
      WBPaper00060811:L1_vs_adult_upregulated_neural
      WBPaper00061377:MYRF-1_interacting
      WBPaper00061478:SUMO-conjugated_protein
      WBPaper00061527:dld-1-skn-1_16701
      WBPaper00061527:nhr-46_2300-unc-108_2961
      WBPaper00061651:AIZ_enriched
      WBPaper00061651:VA12_enriched
      WBPaper00061651:VB01_enriched
      WBPaper00061651:VB02_enriched
      WBPaper00061651:VB_enriched
      WBPaper00062325:muscle_enriched_coding-RNA
      WBPaper00062554:MAGU-2_interacting
      WBPaper00062669:extracellular-vesicle_protein
      WBPaper00063930:BRD-1_interacting
      WBPaper00064005:starvation_upregulated_N2_mRNA
      WBPaper00064055:trl-1(cas1077)_downregulated_starved
      WBPaper00064071:NHR-49_interacting
      WBPaper00064716:paraquat_upregulated
      WBPaper00065120:body-muscle-transcriptome
      WBPaper00065158:AFD_depleted
      WBPaper00065258:anchor-cell_enriched
      cgc4386_cluster_4_4
      WBPaper00025032:cluster_3
      WBPaper00025032:cluster_19
      WBPaper00025141:N2_Expressed_Genes
      WBPaper00025141:unc-4::GFP_Expressed_Genes
      WBPaper00026929:sir-2.1_overexpression_regulated
      WBPaper00026980:intestine_enriched
      WBPaper00035560:ahr-1_downregulated
      WBPaper00035905:FBF-1_Associated
      WBPaper00036123:Atrazine_regulated
      WBPaper00036286:Pattern_F
      WBPaper00037147:heatshock_upregulated
      WBPaper00040210:Chlorpyrifos_Diazinon_24C_regulated
      WBPaper00040603:tdp-1(lf)_down_vs_N2_FC_1.2
      WBPaper00040603:tdp-1(lf)_down_vs_N2_FC_1.5
      WBPaper00041606:CE_B.thuringiensis-DB27_regulated
      WBPaper00041606:CE_X.nematophila_regulated
      [cgc5767]:cluster_3
      [cgc5767]:expression_class_M
      [cgc5767]:expression_class_MD
      [cgc5767]:expression_class_MD_pd(66_min)
      [cgc5767]:expression_class_SM
      [cgc5767]:expression_class_SMD
    Interaction (169)
  Map_info: Map: IV Position: 4.82672 Error: 0.002948
    Well_ordered
    Positive: Positive_clone: M7 Inferred_automatically: From sequence, transcript, pseudogene data
        PC#2-1
    Negative: Outside_rearr: sDf60
    Mapping_data: 2_point: 1006
      Multi_point: 803
      Pos_neg_data: 1007
        1008
        1009
        1010
        1011
        3814
        3850
        8003
        8045
        8288
  Reference (45)
  Remark: [BC Lab] Essential gene. Phenotype of different homozygous alleles range from early to mid larval development.
    This gene is now the primary name again for ubc-2. Previously, let-70 was made an 'Other_name' for ubc-2. 02/06/12 krb.
  Method: Gene