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WormBase Tree Display for Gene: WBGene00001898

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Name Class

WBGene00001898SMapS_parentSequenceM163
IdentityVersion2
NameCGC_namehis-24Person_evidenceWBPerson160
Sequence_nameM163.3
Molecular_nameM163.3
M163.3.1
CE12450
Other_nameHH1
H1.1Paper_evidenceWBPaper00004630
Histone H1.1Paper_evidenceWBPaper00053345
CELE_M163.3Accession_evidenceNDBBX284606
Public_namehis-24
DB_infoDatabaseAceViewgeneXP109
WormQTLgeneWBGene00001898
WormFluxgeneWBGene00001898
NDBlocus_tagCELE_M163.3
PanthergeneCAEEL|WormBase=WBGene00001898|UniProtKB=P10771
familyPTHR11467
NCBIgene181545
RefSeqproteinNM_078009.7
SwissProtUniProtAccP10771
UniProt_GCRPUniProtAccP10771
SpeciesCaenorhabditis elegans
HistoryVersion_change107 Apr 2004 11:29:26WBPerson1971EventImportedInitial conversion from geneace
212 Nov 2010 10:24:40WBPerson2970Name_changeOther_nameH1.1
StatusLive
Gene_infoBiotypeSO:0001217
Gene_classhis
Allele (33)
Legacy_information[C.elegansII] NMK. Histone type H1. Contains intron, encodes polyadenylated RNA. [Sanicola et al. 1990]
StrainWBStrain00031772
WBStrain00034782
WBStrain00034807
WBStrain00006458
RNASeq_FPKM (74)
GO_annotation (30)
Ortholog (80)
ParalogWBGene00001852Caenorhabditis elegansFrom_analysisTreeFam
Panther
WormBase-Compara
WBGene00001853Caenorhabditis elegansFrom_analysisTreeFam
Panther
WormBase-Compara
WBGene00001854Caenorhabditis elegansFrom_analysisTreeFam
Panther
WormBase-Compara
WBGene00001855Caenorhabditis elegansFrom_analysisTreeFam
Panther
WormBase-Compara
WBGene00001856Caenorhabditis elegansFrom_analysisTreeFam
Panther
WormBase-Compara
WBGene00001857Caenorhabditis elegansFrom_analysisTreeFam
Panther
WormBase-Compara
Structured_descriptionConcise_descriptionhis-24 encodes one of eight C. elegans H1 linker histones; HIS-24, along with the histone deacetylase SIR-2.1 and the Enhancer of zeste E(Z) ortholog MES-2, plays a key role in heterochromatin regulation and thus, in regulation of fertility and embryonic development; specifically, HIS-24 and SIR-2.1 are essential for maintenance of the histone H3K27me3 mark at subtelomeric regions in the C. elegans germ line; HIS-24 interacts specifically with the H3 K27 region, either when unmodified or when in the trimethylated (me3) state; HIS-24 is ubiquitously expressed and localizes to nuclei; in addition, in germ cells, the majority of HIS-24 localizes to the cytoplasm, in a manner dependent upon SIR-2.1 and MES proteins.Paper_evidenceWBPaper00004630
WBPaper00028983
WBPaper00033091
Curator_confirmedWBPerson1843
WBPerson567
Date_last_updated17 Nov 2010 00:00:00
Automated_descriptionEnables H3K27me3 modified histone binding activity. Involved in defense response to Gram-positive bacterium and negative regulation of gene expression. Located in chromosome, telomeric region; cytoplasm; and nucleus. Expressed in several structures, including germ line and gonad. Is an ortholog of human H1-0 (H1.0 linker histone) and H1-8 (H1.8 linker histone).Paper_evidenceWBPaper00065943
Curator_confirmedWBPerson324
WBPerson37462
Inferred_automaticallyThis description was generated automatically by a script based on data from the WS291 version of WormBase
Date_last_updated29 Nov 2023 00:00:00
Molecular_infoCorresponding_CDSM163.3
Corresponding_transcriptM163.3.1
Other_sequenceCRC10456_1
Tcir_isotig18885
CSC00881_1
CBC00664_1
Tcol_isotig01264
Tcol_isotig01265
CRC09538_1
HCC00284_1
AS01474
CJC11638_1
BXC03798_1
CBC00664_2
CRC01284_1
JO470002.1
HC03897
CR08901
EX553299.1
Tcol_isotig04790
Oden_isotig13392
CR00662
PPC14799_1
CB037840.1
Tcol_isotig04789
Tcol_isotig22590
Tcol_isotig01266
CRC06438_1
JI215151.1
Tcir_isotig20441
CRC10725_1
Acan_isotig02450
PPC00439_1
CRC01978_1
CR02530
Tcol_isotig01262
CR02093
FD516780.1
ASC27424_1
FE914425.1
Tcol_isotig18360
JI182697.1
Name_isotig00729
BXC07629_1
CR02589
FD517769.1
FD514089.1
PPC11097_1
FD514604.1
EX553807.1
NAC00202_1
PPC04914_1
Tcir_isotig01512
TDC01223_1
Acan_isotig02449
PPC01935_1
Tcir_isotig07047
CRC09308_1
JI170446.1
FD515554.1
CRC02221_1
FD514861.1
CRC09253_1
Oden_isotig21735
FD514112.1
CJC00374_1
CRC06533_1
Tcol_isotig01263
CRC02001_1
CBC03532_1
JI212502.1
CRC07974_1
ASC00643_1
CRC11074_1
Tcol_isotig01267
PP00532
Tcol_isotig20089
ACC04772_1
Associated_feature (15)
Experimental_infoRNAi_resultWBRNAi00090698Inferred_automaticallyRNAi_primary
WBRNAi00017226Inferred_automaticallyRNAi_primary
WBRNAi00089638Inferred_automaticallyRNAi_primary
WBRNAi00027719Inferred_automaticallyRNAi_primary
WBRNAi00089608Inferred_automaticallyRNAi_primary
WBRNAi00050989Inferred_automaticallyRNAi_primary
WBRNAi00076026Inferred_automaticallyRNAi_primary
WBRNAi00076031Inferred_automaticallyRNAi_primary
WBRNAi00064599Inferred_automaticallyRNAi_primary
WBRNAi00076030Inferred_automaticallyRNAi_primary
Expr_pattern (15)
Drives_constructWBCnstr00000408
WBCnstr00000430
WBCnstr00002522
WBCnstr00007280
WBCnstr00009451
WBCnstr00013533
WBCnstr00015453
WBCnstr00015912
WBCnstr00036616
Construct_productWBCnstr00000408
WBCnstr00000540
WBCnstr00004606
WBCnstr00004608
WBCnstr00004609
WBCnstr00004610
WBCnstr00004611
WBCnstr00004612
WBCnstr00004613
WBCnstr00004614
WBCnstr00004693
WBCnstr00007280
WBCnstr00007487
WBCnstr00007489
WBCnstr00007490
WBCnstr00007813
WBCnstr00007817
WBCnstr00007818
WBCnstr00007819
WBCnstr00009451
WBCnstr00009552
WBCnstr00009609
WBCnstr00014443
WBCnstr00014803
WBCnstr00014854
WBCnstr00014942
WBCnstr00015138
WBCnstr00015139
WBCnstr00015140
WBCnstr00015141
WBCnstr00015142
WBCnstr00015143
WBCnstr00015144
WBCnstr00015145
WBCnstr00015146
WBCnstr00015147
WBCnstr00015148
WBCnstr00015149
WBCnstr00015150
WBCnstr00015151
WBCnstr00015152
WBCnstr00015153
WBCnstr00015154
WBCnstr00015155
WBCnstr00015156
WBCnstr00015157
WBCnstr00015158
WBCnstr00015159
WBCnstr00015160
WBCnstr00015161
WBCnstr00015162
WBCnstr00015163
WBCnstr00015164
WBCnstr00015165
WBCnstr00015166
WBCnstr00015167
WBCnstr00015168
WBCnstr00015169
WBCnstr00015170
WBCnstr00015171
WBCnstr00015172
WBCnstr00015173
WBCnstr00015174
WBCnstr00015175
WBCnstr00015176
WBCnstr00015177
WBCnstr00015178
WBCnstr00015179
WBCnstr00015180
WBCnstr00015181
WBCnstr00015182
WBCnstr00015183
WBCnstr00015184
WBCnstr00015185
WBCnstr00015186
WBCnstr00015187
WBCnstr00015188
WBCnstr00015189
WBCnstr00015190
WBCnstr00015191
WBCnstr00015192
WBCnstr00015193
WBCnstr00015194
WBCnstr00015195
WBCnstr00015196
WBCnstr00015197
WBCnstr00015198
WBCnstr00015199
WBCnstr00015200
WBCnstr00015201
WBCnstr00015202
WBCnstr00015203
WBCnstr00015204
WBCnstr00015205
WBCnstr00015206
WBCnstr00015207
WBCnstr00015208
WBCnstr00015209
WBCnstr00015210
WBCnstr00015211
WBCnstr00015212
WBCnstr00015213
WBCnstr00015214
WBCnstr00015215
WBCnstr00015216
WBCnstr00015217
WBCnstr00015218
WBCnstr00015219
WBCnstr00015220
WBCnstr00015221
WBCnstr00015222
WBCnstr00015223
WBCnstr00015224
WBCnstr00015225
WBCnstr00015226
WBCnstr00015227
WBCnstr00015228
WBCnstr00015229
WBCnstr00015230
WBCnstr00015231
WBCnstr00015232
WBCnstr00015233
WBCnstr00015234
WBCnstr00015235
WBCnstr00015236
WBCnstr00015237
WBCnstr00015238
WBCnstr00015239
WBCnstr00015240
WBCnstr00015241
WBCnstr00015242
WBCnstr00015243
WBCnstr00015244
WBCnstr00015245
WBCnstr00015246
WBCnstr00015247
WBCnstr00015248
WBCnstr00015249
WBCnstr00015250
WBCnstr00015251
WBCnstr00015252
WBCnstr00015253
WBCnstr00015254
WBCnstr00015255
WBCnstr00015256
WBCnstr00015257
WBCnstr00015258
WBCnstr00015259
WBCnstr00015260
WBCnstr00015261
WBCnstr00015262
WBCnstr00015263
WBCnstr00015264
WBCnstr00015265
WBCnstr00015266
WBCnstr00015267
WBCnstr00015268
WBCnstr00015269
WBCnstr00015270
WBCnstr00015271
WBCnstr00015272
WBCnstr00015273
WBCnstr00015274
WBCnstr00015275
WBCnstr00015276
WBCnstr00015277
WBCnstr00015278
WBCnstr00015279
WBCnstr00015280
WBCnstr00015281
WBCnstr00015282
WBCnstr00015283
WBCnstr00015284
WBCnstr00015285
WBCnstr00015286
WBCnstr00015287
WBCnstr00015288
WBCnstr00015289
WBCnstr00015290
WBCnstr00015291
WBCnstr00015292
WBCnstr00015293
WBCnstr00015294
WBCnstr00015295
WBCnstr00015296
WBCnstr00015297
WBCnstr00015298
WBCnstr00015299
WBCnstr00015300
WBCnstr00015301
WBCnstr00015302
WBCnstr00015303
WBCnstr00015304
WBCnstr00015305
WBCnstr00015306
WBCnstr00015307
WBCnstr00015308
WBCnstr00015309
WBCnstr00015310
WBCnstr00015311
WBCnstr00015312
WBCnstr00015313
WBCnstr00015314
WBCnstr00015315
WBCnstr00015316
WBCnstr00015317
WBCnstr00015318
WBCnstr00015319
WBCnstr00015320
WBCnstr00015321
WBCnstr00015322
WBCnstr00015323
WBCnstr00015324
WBCnstr00015325
WBCnstr00015326
WBCnstr00015327
WBCnstr00015328
WBCnstr00015329
WBCnstr00015330
WBCnstr00015331
WBCnstr00015332
WBCnstr00015333
WBCnstr00015334
WBCnstr00015335
WBCnstr00015336
WBCnstr00015337
WBCnstr00015338
WBCnstr00015339
WBCnstr00015340
WBCnstr00015341
WBCnstr00015342
WBCnstr00015343
WBCnstr00015344
WBCnstr00015345
WBCnstr00015346
WBCnstr00015347
WBCnstr00015348
WBCnstr00015349
WBCnstr00015350
WBCnstr00015351
WBCnstr00015352
WBCnstr00015932
WBCnstr00015933
WBCnstr00015934
WBCnstr00015935
WBCnstr00015936
WBCnstr00015937
WBCnstr00015938
WBCnstr00015939
WBCnstr00015940
WBCnstr00015941
WBCnstr00015942
WBCnstr00015943
WBCnstr00015944
WBCnstr00015945
WBCnstr00016501
WBCnstr00016502
WBCnstr00016503
WBCnstr00016504
WBCnstr00016505
WBCnstr00016506
WBCnstr00016508
WBCnstr00016509
WBCnstr00016510
WBCnstr00016512
WBCnstr00016513
WBCnstr00016514
WBCnstr00016515
WBCnstr00016516
WBCnstr00016517
WBCnstr00016518
WBCnstr00016519
WBCnstr00016520
WBCnstr00016523
WBCnstr00016524
WBCnstr00017045
WBCnstr00017939
WBCnstr00018077
WBCnstr00018226
WBCnstr00018227
WBCnstr00018313
WBCnstr00018316
WBCnstr00018318
WBCnstr00018319
WBCnstr00018321
WBCnstr00018391
WBCnstr00018476
WBCnstr00019603
WBCnstr00020357
WBCnstr00021099
WBCnstr00021740
WBCnstr00022963
WBCnstr00036616
Regulate_expr_clusterWBPaper00041609:hpl-1_hpl-2_downregulated
WBPaper00041609:hpl-1_hpl-2_upregulated
AntibodyWBAntibody00000355
WBAntibody00001210
WBAntibody00002298
Microarray_resultsSMD_M163.3
175662_at
190225_s_at
A_12_P113258
A_12_P166719
A_12_P166720
A_12_P166721
A_12_P166722
A_12_P166723
Aff_M163.3
GPL13394_WBGene00001898
GPL13914_M163.3
GPL14144_M163.3_111-170_0.924_18_B
GPL14144_M163.3_243-302_0.682_114_C
GPL14144_M163.3_78-137_0.935_12_A
GPL19516_CGZ0030190
GPL21109_M163.3
GPL3518_CE12450
GPL8304_CE_WBGene00001898_A
GPL8304_CE_WBGene00001898_B
GPL8304_CE_WBGene00001898_C
GPL8673_M163_3P00069
GPL8673_M163_3P00163
GPL8673_M163_3P00243
GPL9450_M163.3
cea2.c.47119
Expression_cluster (392)
Interaction (157)
WBProcessWBbiopr:00000008
WBbiopr:00000039
Map_infoMapXPosition16.7093Error0.005353
PositivePositive_cloneLCEH1A
M163Inferred_automaticallyFrom sequence, transcript, pseudogene data
Pseudo_map_position
Reference (29)
RemarkMap position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC.CGC_data_submission
MethodGene