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WormBase Tree Display for Gene: WBGene00004271

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Name Class

WBGene00004271SMapS_parentSequenceW03C9
IdentityVersion1
NameCGC_namerab-7Person_evidenceWBPerson451
Sequence_nameW03C9.3
Molecular_nameW03C9.3
W03C9.3.1
CE03777
Other_nameCELE_W03C9.3Accession_evidenceNDBBX284602
Public_namerab-7
DB_infoDatabase (11)
SpeciesCaenorhabditis elegans
HistoryVersion_change107 Apr 2004 11:29:34WBPerson1971EventImportedInitial conversion from geneace
StatusLive
Gene_info (11)
Disease_infoExperimental_modelDOID:9970Homo sapiensPaper_evidenceWBPaper00030935
Accession_evidenceOMIM601665
Curator_confirmedWBPerson324
Date_last_updated30 Jan 2013 00:00:00
Potential_modelDOID:0110159Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:9788)
Disease_relevanceStudies in C. elegans suggest that the small Rab GTPase RAB-7 and the Rab-GTPase-activating protein RBG-3 are involved in a tub-1/tubby mediated endocytic pathway that increases fat storage; tub-1/tubby is a gene involved in obesity across species; tub-1 also interacts with RBG-3 in ciliated neurons to possibly modulate neurohormonal and chemosensory function in the regulation of fat storage.Homo sapiensPaper_evidenceWBPaper00031329
WBPaper00038404
Accession_evidenceOMIM203750
601665
Curator_confirmedWBPerson324
Date_last_updated12 Jan 2012 00:00:00
Models_disease_in_annotationWBDOannot00000028
Molecular_infoCorresponding_CDSW03C9.3
Corresponding_transcriptW03C9.3.1
Other_sequence (45)
Associated_featureWBsf650634
WBsf666217
WBsf224016
WBsf224017
Experimental_infoRNAi_result (75)
Expr_pattern (11)
Drives_constructWBCnstr00012363
WBCnstr00020664
WBCnstr00042405
Construct_productWBCnstr00000244
WBCnstr00000245
WBCnstr00000255
WBCnstr00001410
WBCnstr00001776
WBCnstr00001796
WBCnstr00001803
WBCnstr00001815
WBCnstr00005661
WBCnstr00005662
WBCnstr00005794
WBCnstr00006085
WBCnstr00006087
WBCnstr00006090
WBCnstr00006423
WBCnstr00007015
WBCnstr00008061
WBCnstr00008210
WBCnstr00008285
WBCnstr00008431
WBCnstr00009005
WBCnstr00013097
WBCnstr00013129
WBCnstr00014502
WBCnstr00017632
WBCnstr00017636
WBCnstr00018951
WBCnstr00019168
WBCnstr00019186
WBCnstr00019200
WBCnstr00020664
WBCnstr00022453
WBCnstr00022461
WBCnstr00023032
WBCnstr00038380
WBCnstr00042405
AntibodyWBAntibody00001207
WBAntibody00002256
Microarray_results (21)
Expression_clusterWBPaper00032031:DConiospora_downregulated_OligoArray_24h
WBPaper00035073:mitochondria_protein
WBPaper00036375:enriched_in_PVD_OLL
WBPaper00037047:aging_accelerated_insoluble_protein
WBPaper00037047:insoluble_protein
WBPaper00037950:dopaminergic-neurons_larva_enriched
WBPaper00038289:oocyte_protein
WBPaper00040285:H2S_24hr_upregulated
WBPaper00040965:lipid-droplet_associated_protein
WBPaper00044128:DietaryRestriction_upregulated
WBPaper00044501:gld-1_let-7_regulated
WBPaper00044736:flat_dev_expression
WBPaper00044786:emr-1(RNAi);lem-2(tm1582)_downregulated
WBPaper00045420:fertilization_downregulated_transcript
WBPaper00045521:Oogenic
WBPaper00046012:tdp-1(ok803)_downregulated
WBPaper00046509:htz-1(ok3099)_upregulated
WBPaper00048988:neuron_expressed
WBPaper00049545:jmjd-3.1(+)_downregulated
WBPaper00049545:sur-5p-jmjd-1.2(+)_downregulated
WBPaper00050182:lmn-1(L535P)_downregulated
WBPaper00050488:adult_vs_dauer_regulated_N2_20C
WBPaper00050488:N2_vs_mir-34(gk437)_regulated_dauer_20C
WBPaper00050488:N2_vs_mir-34(OverExpression)_regulated_dauer_20C
WBPaper00050726:OsmoticStress_regulated_Food
WBPaper00050990:arcade_intestinal-valve_expressed
WBPaper00050990:body-muscle_expressed
WBPaper00050990:GABAergic-neuron_expressed
WBPaper00050990:hypodermis_expressed
WBPaper00050990:intestine_expressed
WBPaper00050990:NMDA-neuron_expressed
WBPaper00050990:pharynx_expressed
WBPaper00050990:seam_expressed
WBPaper00051245:body-wall-muscle_cytoplasm_expressed
WBPaper00051245:epidermis_cytoplasm_expressed
WBPaper00051245:epidermis_nucleus_expressed
WBPaper00051245:intestine_cytoplasm_expressed
WBPaper00052884:emb-4(hc60)_upregulated
WBPaper00053184:sma-2(rax5)_downregulated
WBPaper00053184:sma-4(rax3)_downregulated
WBPaper00053713:Pheromone-induced_postdauer_vs_control_upregulated
WBPaper00053814:25C_downregulated_PY79
WBPaper00054410:set-26(tm2467)_downregulated
WBPaper00055049:S.gordonii_upregulated
WBPaper00055648:germline_expressed
WBPaper00056139:soil-microbiota_upregulated
WBPaper00056443:sek-1(km4)_downregulated
WBPaper00056471:aak-1(tm1944);aak-2(ok524)_downregulated
WBPaper00056471:S.aureus-4h_upregulated_N2
WBPaper00057288:Cold_upregulated_transcript
WBPaper00058598:sin-3(tm1276)_downregulated
WBPaper00058958:100mGy-irradiation-72h_upregulated
WBPaper00060100:SiNP_upregulated_mRNA
WBPaper00060811:L1_vs_adult_upregulated_neural
WBPaper00061203:let-418(n3536)_upregulated
WBPaper00061203:sin-3(tm1276)_upregulated
WBPaper00061203:spr-1(ok2144)_upregulated
WBPaper00061340:Intestinal_and_rectal_muscle
WBPaper00061439:unc-30(ok613)_upregulated
WBPaper00061478:SUMO-conjugated_protein
WBPaper00061527:T23B5.3_15993-C17D12.1
WBPaper00061902:camt-1(ok515)_regulated_RMG
WBPaper00061902:camt-1(ok515)_regulated_URX-AQR-PQR
WBPaper00062193:skn-1(RNAi)_upregulated
WBPaper00062325:muscle_enriched_coding-RNA
WBPaper00062554:MAGU-2_interacting
WBPaper00062669:extracellular-vesicle_protein
WBPaper00064071:NHR-49_interacting
WBPaper00064088:Day-1-adult_vs_L4_upregulated_daf-16(mu86);glp-1(e2141)
WBPaper00064088:Day-3-adult_vs_L4_upregulated_daf-16(mu86);glp-1(e2141)
WBPaper00064088:Day-3-adult_vs_L4_upregulated_glp-1(e2141)
WBPaper00064107:lin-35(n745)_downregulated
WBPaper00064201:SNA-3_interacting
WBPaper00064716:paraquat_upregulated
WBPaper00064992:Eugenol_downregulated
WBPaper00065120:body-muscle-transcriptome
WBPaper00065373:Cisplatin_upregulated_WT
WBPaper00025141:N2_Expressed_Genes
WBPaper00025141:unc-4::GFP_Expressed_Genes
WBPaper00026929:sir-2.1_overexpression_regulated
WBPaper00026980:intestine_enriched
WBPaper00027111:eri-1(mg366)_upregulated
WBPaper00031832:slr-2_regulated
WBPaper00034739:N2lessDR1350
WBPaper00035905:FBF-1_Associated
WBPaper00036123:Cadmium_regulated
WBPaper00037611:RNP-8-associated
WBPaper00040603:tdp-1(lf)_down_vs_N2_FC_1.2
WBPaper00040821:Au-NP_regulated
WBPaper00041174:genotypic
WBPaper00041174:genotypic_prime
WBPaper00041606:CE_B.thuringiensis-DB27_regulated
WBPaper00041606:CE_X.nematophila_regulated
WBPaper00041939:control_vs_UVC-exposed_24h
WBPaper00041939:EtBr-exposed_vs_UVC-exposed_24h
WBPaper00041939:UVC-EtBr-exposed_vs_UVC-exposed_51h
WBPaper00044535:male_upregulated
WBPaper00045263:0.1mM-paraquat_upregulated
WBPaper00045263:nuo-6(qm200)_upregulated
WBPaper00053236:Starvation_regulated_GR1307
WBPaper00053236:Starvation_regulated_N2
WBPaper00055899:nitroguanidine_regulated
[cgc6390]:mixed_oogenesis-somatic
Interaction (96)
WBProcessWBbiopr:00000015
Map_infoMapIIPosition4.64486Error0.24308
PositivePositive_cloneW03C9Inferred_automaticallyFrom CDS info
From sequence, transcript, pseudogene data
Mapping_dataMulti_point4619
Pseudo_map_position
Reference (132)
RemarkMap position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC.CGC_data_submission
MethodGene