Questions, Feedback & Help
Send us an email and we'll get back to you ASAP. Or you can read our Frequently Asked Questions.

WormBase Tree Display for Gene: WBGene00006890

expand all nodes | collapse all nodes | view schema

Name Class

WBGene00006890EvidenceCGC_data_submission
SMapS_parentSequenceK07E3
IdentityVersion1
NameCGC_namevem-1Person_evidenceWBPerson1835
Sequence_nameK07E3.8
Molecular_nameK07E3.8
K07E3.8.1
CE34578
Other_nameCELE_K07E3.8Accession_evidenceNDBBX284606
Public_namevem-1
DB_infoDatabase (9)
SpeciesCaenorhabditis elegans
HistoryVersion_change107 Apr 2004 11:29:43WBPerson1971EventImportedInitial conversion from geneace
StatusLive
Gene_infoBiotypeSO:0001217
Gene_classvem
AlleleWBVar00599144
WBVar01981044
WBVar01884644
WBVar01499781
WBVar02151886
WBVar00146307
WBVar00092327
WBVar01499642
WBVar01500012
WBVar01500013
WBVar00241652
WBVar00509944
WBVar00509945
WBVar00509946
WBVar00509947
WBVar00509948
WBVar00509949
WBVar00509950
WBVar00509951
WBVar00509952
WBVar00081078
WBVar01816162
WBVar01165200
WBVar01165201
WBVar01165202
WBVar01165203
WBVar01165204
WBVar01165205
WBVar01165206
WBVar01165207
WBVar01165208
WBVar01498960
WBVar00145627
WBVar01500067
StrainWBStrain00035774
WBStrain00035993
RNASeq_FPKM (74)
GO_annotation00082942
00082943
00082944
00082945
00082946
00082947
00082948
00082949
00082950
00082951
Ortholog (41)
ParalogWBGene00006478Caenorhabditis elegansFrom_analysisPanther
WormBase-Compara
WBGene00012559Caenorhabditis elegansFrom_analysisPanther
WormBase-Compara
Structured_descriptionConcise_descriptionvem-1 encodes a transmembrane protein that contains a cytochrome b5-like heme/steroid-binding domain and is orthologous to mammalian VEMA, a membrane-associated progesterone receptor component; in C. elegans, vem-1 is required for proper axonal guidance of ventral nerve cord neurons; vem-1 interacts genetically with unc-40, whose protein product also interacts with VEM-1; a VEM-1::GFP reporter fusion is expressed from embryonic stages through late larval stages and is found in a subset of neurons, including the AVG pioneer neurons, that extend processes into the ventral nerve cord; microarray experiments indicate that vem-1 transcripts are upregulated in response to treatment with xenobiotics such as clofibrate and beta-naphthoflavone.Paper_evidenceWBPaper00024484
WBPaper00026820
Curator_confirmedWBPerson1843
Date_last_updated26 Feb 2009 00:00:00
Automated_descriptionInvolved in innate immune response. Located in axon. Expressed in AVG; head neurons; and somatic nervous system. Is an ortholog of human PGRMC1 (progesterone receptor membrane component 1).Paper_evidenceWBPaper00065943
Curator_confirmedWBPerson324
WBPerson37462
Inferred_automaticallyThis description was generated automatically by a script based on data from the WS291 version of WormBase
Date_last_updated29 Nov 2023 00:00:00
Molecular_infoCorresponding_CDSK07E3.8
Corresponding_CDS_historyK07E3.8a:wp252
Corresponding_transcriptK07E3.8.1
Other_sequence (28)
Associated_featureWBsf654188
WBsf654189
WBsf654190
WBsf654191
WBsf670808
WBsf982206
WBsf1006049
Experimental_infoRNAi_resultWBRNAi00061111Inferred_automaticallyRNAi_primary
WBRNAi00050171Inferred_automaticallyRNAi_primary
WBRNAi00061112Inferred_automaticallyRNAi_primary
WBRNAi00016735Inferred_automaticallyRNAi_primary
Expr_patternExpr3106
Expr1011310
Expr1032922
Expr1153866
Expr2017966
Expr2036102
Drives_constructWBCnstr00001989
WBCnstr00034111
Construct_productWBCnstr00034111
Microarray_results (22)
Expression_cluster (157)
Interaction (20)
Map_infoMapXPosition-0.581887Error0.008927
PositivePositive_cloneK07E3Inferred_automaticallyFrom sequence, transcript, pseudogene data
Mapping_dataMulti_point4259
4404
4750
Pseudo_map_position
ReferenceWBPaper00018032
WBPaper00024484
WBPaper00026820
WBPaper00033099
WBPaper00038491
WBPaper00048021
WBPaper00050498
WBPaper00055090
RemarkSequence connection from [Runko E, Kaprielian Z]
Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC.CGC_data_submission
MethodGene