WormBase Tree Display for Gene: WBGene00004945
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WBGene00004945 | Evidence | Person_evidence | WBPerson160 | ||||
---|---|---|---|---|---|---|---|
SMap | S_parent | Sequence | CHROMOSOME_II | ||||
Identity (6) | |||||||
Gene_info | Biotype | SO:0001217 | |||||
Gene_class | sop | ||||||
Allele | WBVar00092630 | Inferred_automatically | From strain object: VC937 | ||||
WBVar02033839 | |||||||
WBVar01499702 | |||||||
WBVar00380276 | |||||||
WBVar00380277 | |||||||
WBVar00311299 | |||||||
WBVar00311300 | |||||||
WBVar00380278 | |||||||
WBVar00380279 | |||||||
WBVar00311301 | |||||||
WBVar00311302 | |||||||
WBVar00380280 | |||||||
WBVar00311303 | |||||||
WBVar00380281 | |||||||
WBVar00311304 | |||||||
WBVar00380282 | |||||||
WBVar00311305 | |||||||
WBVar00380283 | |||||||
WBVar00380284 | |||||||
WBVar00311306 | |||||||
WBVar00380285 | |||||||
WBVar00380286 | |||||||
WBVar00380287 | |||||||
WBVar01258673 | |||||||
WBVar00380288 | |||||||
WBVar01835463 | |||||||
WBVar01835464 | |||||||
WBVar01835465 | |||||||
WBVar01498435 | |||||||
WBVar01835466 | |||||||
WBVar01258684 | |||||||
WBVar02086400 | |||||||
WBVar02067097 | |||||||
WBVar01247185 | |||||||
WBVar01247186 | |||||||
WBVar01247187 | |||||||
WBVar01247188 | |||||||
WBVar01247193 | |||||||
WBVar01247194 | |||||||
WBVar01247196 | |||||||
WBVar01491846 | |||||||
WBVar01505103 | |||||||
WBVar01499956 | |||||||
WBVar01406076 | |||||||
WBVar00234943 | |||||||
WBVar00177366 | |||||||
WBVar00177367 | |||||||
WBVar00177369 | |||||||
WBVar00000522 | |||||||
WBVar00177370 | |||||||
WBVar00177371 | |||||||
WBVar00177372 | |||||||
WBVar00177373 | |||||||
WBVar00177374 | |||||||
WBVar00177375 | |||||||
WBVar00774725 | |||||||
WBVar00774726 | |||||||
WBVar00774727 | |||||||
WBVar00774728 | |||||||
WBVar00774729 | |||||||
WBVar00774730 | |||||||
WBVar00774731 | |||||||
WBVar00774732 | |||||||
WBVar01892047 | |||||||
WBVar00774733 | |||||||
WBVar01936172 | |||||||
WBVar01936173 | |||||||
WBVar00774734 | |||||||
WBVar01892048 | |||||||
WBVar00774736 | |||||||
WBVar01892049 | |||||||
WBVar00774737 | |||||||
WBVar01892050 | |||||||
WBVar01892051 | |||||||
WBVar00774738 | |||||||
WBVar00774739 | |||||||
WBVar01440594 | |||||||
WBVar01892052 | |||||||
WBVar00774740 | |||||||
WBVar01440595 | |||||||
WBVar01655440 | |||||||
WBVar00774741 | |||||||
WBVar01655441 | |||||||
WBVar00774742 | |||||||
WBVar00774743 | |||||||
WBVar00774744 | |||||||
WBVar00774745 | |||||||
WBVar01314293 | |||||||
WBVar01314294 | |||||||
WBVar00774746 | |||||||
WBVar01314297 | |||||||
WBVar00774747 | |||||||
WBVar00774748 | |||||||
WBVar01314301 | |||||||
WBVar00774749 | |||||||
WBVar01314304 | |||||||
WBVar00774750 | |||||||
WBVar00000594 | |||||||
WBVar00774751 | |||||||
WBVar00774752 | |||||||
WBVar00774753 | |||||||
WBVar00774754 | |||||||
WBVar00774755 | |||||||
WBVar00774756 | |||||||
WBVar00774757 | |||||||
WBVar00774758 | |||||||
WBVar02130866 | |||||||
WBVar00774759 | |||||||
WBVar02130867 | |||||||
WBVar00774760 | |||||||
WBVar00774761 | |||||||
WBVar00774762 | |||||||
WBVar00774763 | |||||||
WBVar02040699 | |||||||
WBVar02074665 | |||||||
WBVar02040700 | |||||||
WBVar01605484 | |||||||
WBVar01605485 | |||||||
WBVar01605487 | |||||||
WBVar01605488 | |||||||
WBVar01605489 | |||||||
WBVar01605490 | |||||||
WBVar01605491 | |||||||
WBVar00554098 | |||||||
WBVar01605492 | |||||||
WBVar00554102 | |||||||
WBVar00554103 | |||||||
WBVar00554104 | |||||||
WBVar01378791 | |||||||
WBVar01378792 | |||||||
WBVar01378793 | |||||||
WBVar01498941 | |||||||
WBVar01378801 | |||||||
WBVar00230209 | |||||||
WBVar00230210 | |||||||
WBVar00230214 | |||||||
WBVar00230216 | |||||||
WBVar00106175 | |||||||
WBVar00276118 | |||||||
WBVar01493440 | |||||||
WBVar00298290 | |||||||
Strain | WBStrain00036186 | ||||||
WBStrain00007188 | |||||||
WBStrain00008579 | |||||||
RNASeq_FPKM (74) | |||||||
GO_annotation (32) | |||||||
Ortholog | WBGene00070774 | Caenorhabditis remanei | From_analysis | OMA | |||
WBGene00060128 | Caenorhabditis remanei | From_analysis | Inparanoid_8 | ||||
Sp34_20051800 | Caenorhabditis inopinata | From_analysis | WormBase-Compara | ||||
chrII_pilon.g6141 | Caenorhabditis elegans | From_analysis | WormBase-Compara | ||||
WBGene00125506 | Caenorhabditis japonica | From_analysis | WormBase-Compara | ||||
Paralog | WBGene00010552 | Caenorhabditis elegans | From_analysis | TreeFam | |||
WormBase-Compara | |||||||
Structured_description | Concise_description | sop-2 encodes a SAM domain-containing protein that is related to, but not orthologous with, Polycomb group proteins and ETS transcription factors; during development, SOP-2 activity is required for the proper integration of sexual, spatial, and temporal information during cell fate specification; specifically, SOP-2 is required for maintaining a restricted pattern of Hox gene expression, such as that of mab-5 and egl-5, to specific cells and tissues such as the serotonergic and dopaminergic male tail neurons and the ventral nerve cord; in addition, SOP-2 is required for the proper sexual and temporal specification of the hypodermal seam cells; in regulating temporal fate specification, genetic analyses indicate that sop-2 acts upstream of lin-29 in the heterochronic pathway and interacts with other members of the heterochronic pathway, such as lin-4, let-7, and hbl-1, to integrate temporal information and cell fate specification; sop-2 mutations also result in an increase in ALG-1-containing P bodies in hypodermal seam cells; in regulating neurotransmitter phenotype, sop-2 functions together with sor-3, which also encodes a Polycomb group protein, and members of the TGF-beta signaling pathway; sop-2 and sor-3 also function together to regulate progression through larval development; a SOP-2::GFP reporter fusion is expressed in the nuclei of all somatic cells beginning at the 50-cell stage of embryogenesis; SOP-2::GFP expression is initially diffuse, but by the 200-cell stage is visible in distinct nuclear bodies, the size and number of which may correlate with DNA content. | Paper_evidence | WBPaper00005924 | |||
WBPaper00024202 | |||||||
WBPaper00028988 | |||||||
WBPaper00031488 | |||||||
Curator_confirmed | WBPerson1843 | ||||||
Date_last_updated | 08 Aug 2008 00:00:00 | ||||||
Automated_description | Enables RNA binding activity; protein homodimerization activity; and ubiquitin protein ligase binding activity. Involved in several processes, including negative regulation of cytoplasmic mRNA processing body assembly; neuron differentiation; and regulation of gene expression. Located in nuclear speck. Expressed widely. | Paper_evidence | WBPaper00065943 | ||||
Curator_confirmed | WBPerson324 | ||||||
WBPerson37462 | |||||||
Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||
Date_last_updated | 29 Nov 2023 00:00:00 | ||||||
Molecular_info | Corresponding_CDS | C50E10.4a | |||||
C50E10.4b | |||||||
C50E10.4c | |||||||
Corresponding_CDS_history | C50E10.4:wp89 | ||||||
Corresponding_transcript | C50E10.4a.1 | ||||||
C50E10.4b.1 | |||||||
C50E10.4c.1 | |||||||
Associated_feature | WBsf981311 | ||||||
WBsf990051 | |||||||
WBsf990052 | |||||||
WBsf990053 | |||||||
WBsf1013409 | |||||||
WBsf1013410 | |||||||
WBsf1013411 | |||||||
WBsf222260 | |||||||
WBsf222261 | |||||||
Transcription_factor | WBTranscriptionFactor000203 | ||||||
Experimental_info | RNAi_result (21) | ||||||
Expr_pattern | Expr2597 | ||||||
Expr12241 | |||||||
Expr1025868 | |||||||
Expr1032460 | |||||||
Expr1146873 | |||||||
Expr2016005 | |||||||
Expr2034240 | |||||||
Drives_construct | WBCnstr00000173 | ||||||
WBCnstr00000174 | |||||||
WBCnstr00035311 | |||||||
Construct_product | WBCnstr00035311 | ||||||
Microarray_results (29) | |||||||
Expression_cluster (128) | |||||||
Interaction (55) | |||||||
Map_info | Map | II | Position | 8.55189 | Error | 0.18042 | |
Positive | Positive_clone | C50E10 | Inferred_automatically | From sequence, transcript, pseudogene data | |||
Mapping_data | Multi_point | 4624 | |||||
4686 | |||||||
Pseudo_map_position | |||||||
Reference (28) | |||||||
Remark | Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | |||||
Method | Gene |