WormBase Tree Display for Gene: WBGene00004801
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| WBGene00004801 | SMap | S_parent | Sequence | F46G10 | |||||
|---|---|---|---|---|---|---|---|---|---|
| Identity | Version | 1 | |||||||
| Name | CGC_name | sir-2.2 | Person_evidence | WBPerson1840 | |||||
| Sequence_name | F46G10.7 | ||||||||
| Molecular_name (11) | |||||||||
| Other_name | CELE_F46G10.7 | Accession_evidence | NDB | BX284606 | |||||
| Public_name | sir-2.2 | ||||||||
| DB_info | Database (12) | ||||||||
| Species | Caenorhabditis elegans | ||||||||
| History | Version_change | 1 | 07 Apr 2004 11:29:36 | WBPerson1971 | Event | Imported | Initial conversion from geneace | ||
| Status | Live | ||||||||
| Gene_info | Biotype | SO:0001217 | |||||||
| Gene_class | sir | ||||||||
| Allele | WBVar02152944 | Inferred_automatically | From strain object: HA2040 | ||||||
| WBVar01602377 | |||||||||
| WBVar01499887 | |||||||||
| WBVar01499519 | |||||||||
| WBVar01602378 | |||||||||
| WBVar01602379 | |||||||||
| WBVar01499888 | |||||||||
| WBVar01472019 | |||||||||
| WBVar01498787 | |||||||||
| WBVar01499710 | |||||||||
| WBVar01835267 | |||||||||
| WBVar00084040 | |||||||||
| WBVar00084041 | |||||||||
| WBVar00084042 | |||||||||
| WBVar01487951 | |||||||||
| WBVar01572359 | |||||||||
| WBVar01572360 | |||||||||
| WBVar02140373 | |||||||||
| WBVar00258773 | |||||||||
| WBVar00216842 | |||||||||
| WBVar00521641 | |||||||||
| WBVar00521642 | |||||||||
| WBVar00521643 | |||||||||
| WBVar00521644 | |||||||||
| WBVar00521645 | |||||||||
| WBVar00521646 | |||||||||
| WBVar00521647 | |||||||||
| WBVar00521648 | |||||||||
| WBVar00521649 | |||||||||
| WBVar00521650 | |||||||||
| WBVar00521651 | |||||||||
| WBVar00521652 | |||||||||
| WBVar00521653 | |||||||||
| WBVar00521654 | |||||||||
| WBVar00521655 | |||||||||
| WBVar00521656 | |||||||||
| WBVar00521657 | |||||||||
| WBVar01759803 | |||||||||
| WBVar01200694 | |||||||||
| WBVar01200695 | |||||||||
| WBVar01200696 | |||||||||
| WBVar01200697 | |||||||||
| WBVar01200698 | |||||||||
| WBVar01200699 | |||||||||
| WBVar02027521 | |||||||||
| WBVar01200700 | |||||||||
| WBVar01200701 | |||||||||
| WBVar01200702 | |||||||||
| WBVar01200703 | |||||||||
| WBVar02005326 | |||||||||
| WBVar01200704 | |||||||||
| WBVar01200705 | |||||||||
| WBVar01200706 | |||||||||
| WBVar01200707 | |||||||||
| WBVar01200708 | |||||||||
| WBVar01200709 | |||||||||
| WBVar01200710 | |||||||||
| WBVar01200711 | |||||||||
| WBVar01200712 | |||||||||
| WBVar01200713 | |||||||||
| WBVar01200714 | |||||||||
| WBVar01200715 | |||||||||
| WBVar01200716 | |||||||||
| WBVar01200717 | |||||||||
| WBVar01200718 | |||||||||
| WBVar01200719 | |||||||||
| WBVar01200720 | |||||||||
| WBVar01498720 | |||||||||
| WBVar01679095 | |||||||||
| WBVar01679096 | |||||||||
| WBVar00251497 | |||||||||
| WBVar01497456 | |||||||||
| WBVar00251520 | |||||||||
| WBVar01941663 | |||||||||
| WBVar02052240 | |||||||||
| WBVar01498960 | |||||||||
| WBVar01500067 | |||||||||
| Strain | WBStrain00047283 | ||||||||
| RNASeq_FPKM (74) | |||||||||
| GO_annotation (19) | |||||||||
| Contained_in_operon | CEOPX178 | ||||||||
| CEOP2736 | |||||||||
| Ortholog (31) | |||||||||
| Paralog | WBGene00004802 | Caenorhabditis elegans | From_analysis | TreeFam | |||||
| Inparanoid_8 | |||||||||
| Panther | |||||||||
| WormBase-Compara | |||||||||
| WBGene00004800 | Caenorhabditis elegans | From_analysis | WormBase-Compara | ||||||
| WBGene00004803 | Caenorhabditis elegans | From_analysis | WormBase-Compara | ||||||
| Structured_description | Concise_description | sir-2.2 encodes one of four C. elegans proteins with similarity to the Saccharomyces cerevisiae Sir2p NAD-dependent histone deacetylase; SIR-2.2 may play a role in genomic stability and protecting the genome against mutations, as loss of SIR-2.2 function via RNA-mediated interference (RNAi) results in an increased level of spontaneous mutagenesis. | Paper_evidence | WBPaper00004566 | |||||
| WBPaper00005736 | |||||||||
| Curator_confirmed | WBPerson1843 | ||||||||
| Date_last_updated | 11 May 2009 00:00:00 | ||||||||
| Automated_description | Predicted to enable NAD+ binding activity and NAD-dependent histone deacetylase activity. Involved in innate immune response. Located in mitochondrion. Is an ortholog of human SIRT4 (sirtuin 4). | Paper_evidence | WBPaper00065943 | ||||||
| Curator_confirmed | WBPerson324 | ||||||||
| WBPerson37462 | |||||||||
| Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||||
| Date_last_updated | 29 Nov 2023 00:00:00 | ||||||||
| Molecular_info | Corresponding_CDS | F46G10.7a | |||||||
| F46G10.7b | |||||||||
| F46G10.7c | |||||||||
| Corresponding_CDS_history | F46G10.7:wp109 | ||||||||
| Corresponding_transcript | F46G10.7a.1 | ||||||||
| F46G10.7a.2 | |||||||||
| F46G10.7b.1 | |||||||||
| F46G10.7b.2 | |||||||||
| F46G10.7c.1 | |||||||||
| Other_sequence (15) | |||||||||
| Associated_feature | WBsf648660 | ||||||||
| WBsf236559 | |||||||||
| Experimental_info | RNAi_result (7) | ||||||||
| Expr_pattern | Chronogram1178 | ||||||||
| Expr6092 | |||||||||
| Expr6093 | |||||||||
| Expr10774 | |||||||||
| Expr1027681 | |||||||||
| Expr1151410 | |||||||||
| Expr1200185 | |||||||||
| Expr2015824 | |||||||||
| Expr2034057 | |||||||||
| Drives_construct | WBCnstr00003470 | ||||||||
| WBCnstr00003833 | |||||||||
| WBCnstr00017540 | |||||||||
| WBCnstr00035380 | |||||||||
| Construct_product | WBCnstr00017540 | ||||||||
| WBCnstr00017950 | |||||||||
| WBCnstr00035380 | |||||||||
| Antibody | WBAntibody00002427 | ||||||||
| Microarray_results (27) | |||||||||
| Expression_cluster (98) | |||||||||
| SAGE_tag | SAGE:taatcttgaa | Strand | Antisense | ||||||
| SAGE:atggataaac | Strand | Antisense | |||||||
| SAGE:aaacaaattgccattct | Strand | Antisense | |||||||
| SAGE:aagttccgtt | Strand | Antisense | |||||||
| SAGE:aaacaaattg | Strand | Antisense | |||||||
| SAGE:gcgacgatga | Strand | Sense | |||||||
| Unambiguously_mapped | |||||||||
| SAGE:ccatacttca | Strand | Antisense | |||||||
| SAGE:gcgacgatgaagttaga | Strand | Sense | |||||||
| Unambiguously_mapped | |||||||||
| SAGE:ttaacgttct | Strand | Antisense | |||||||
| Interaction (150) | |||||||||
| Map_info | Map | X | Position | 11.3226 | Error | 0.035645 | |||
| Positive | Positive_clone | F46G10 | Inferred_automatically | From CDS info | |||||
| From sequence, transcript, pseudogene data | |||||||||
| Pseudo_map_position | |||||||||
| Reference (13) | |||||||||
| Remark | Sequence connection from [Tissenbaum HA] | ||||||||
| Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | ||||||||
| Method | Gene |
