scd-1 encodes a novel protein with several regions that are extremely glutamine (Q) rich, interspersed with other residues (usually alanine); SCD-1 affects signalling by proteins in the DAF-7/transforming growth factor (TGF)-beta pathway (DAF-1, DAF-8, and DAF-14), and the Q-rich regions of SCD-1 protein may mediate epigenetic changes of stably heritable tertiary conformation.
Enriched in several structures, including ABalppppppa; ABpraaapppa; head mesodermal cell; neurons; and pharyngeal cell based on Chronogram; microarray; RNA-seq; tiling array; and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and daf-12 based on microarray; tiling array; RNA-seq; and proteomic studies. Is affected by nineteen chemicals including 1-methylnicotinamide; rotenone; and multi-walled carbon nanotube based on RNA-seq and microarray studies.