WormBase Tree Display for Gene: WBGene00004052
expand all nodes | collapse all nodes | view schema
| WBGene00004052 | SMap | S_parent | Sequence | H23L24 | |||||
|---|---|---|---|---|---|---|---|---|---|
| Identity | Version | 2 | |||||||
| Name | CGC_name | parg-2 | Person_evidence | WBPerson236 | |||||
| Sequence_name | H23L24.5 | ||||||||
| Molecular_name | H23L24.5 | ||||||||
| H23L24.5.1 | |||||||||
| CE32685 | |||||||||
| Other_name | pme-4 | ||||||||
| CELE_H23L24.5 | Accession_evidence | NDB | BX284604 | ||||||
| Public_name | parg-2 | ||||||||
| DB_info | Database (12) | ||||||||
| Species | Caenorhabditis elegans | ||||||||
| History | Version_change | 1 | 07 Apr 2004 11:29:34 | WBPerson1971 | Event | Imported | Initial conversion from geneace | ||
| 2 | 18 Nov 2014 11:51:19 | WBPerson2970 | Name_change | CGC_name | parg-2 | ||||
| Other_name | pme-4 | ||||||||
| Status | Live | ||||||||
| Gene_info | Biotype | SO:0001217 | |||||||
| Gene_class | parg | ||||||||
| Allele | WBVar01500079 | ||||||||
| WBVar00928035 | |||||||||
| WBVar00928036 | |||||||||
| WBVar00928037 | |||||||||
| WBVar00928038 | |||||||||
| WBVar00928039 | |||||||||
| WBVar01966744 | |||||||||
| WBVar01854578 | |||||||||
| WBVar00928040 | |||||||||
| WBVar01854579 | |||||||||
| WBVar00928041 | |||||||||
| WBVar01453434 | |||||||||
| WBVar01854580 | |||||||||
| WBVar01854581 | |||||||||
| WBVar01453435 | |||||||||
| WBVar01498996 | |||||||||
| WBVar00928042 | |||||||||
| WBVar01854582 | |||||||||
| WBVar00928043 | |||||||||
| WBVar00928044 | |||||||||
| WBVar00928045 | |||||||||
| WBVar00928046 | |||||||||
| WBVar00928047 | |||||||||
| WBVar00297468 | |||||||||
| WBVar01650028 | |||||||||
| WBVar02148093 | |||||||||
| WBVar01499396 | |||||||||
| WBVar01499397 | |||||||||
| WBVar00092251 | |||||||||
| WBVar00430945 | |||||||||
| WBVar00430946 | |||||||||
| WBVar00430947 | |||||||||
| WBVar00430948 | |||||||||
| WBVar00191190 | |||||||||
| WBVar00191191 | |||||||||
| WBVar00191192 | |||||||||
| WBVar02058118 | |||||||||
| WBVar02058119 | |||||||||
| WBVar00313273 | |||||||||
| WBVar01499633 | |||||||||
| WBVar01482167 | |||||||||
| WBVar01498928 | |||||||||
| WBVar01500245 | |||||||||
| Strain | WBStrain00035943 | ||||||||
| WBStrain00047360 | |||||||||
| WBStrain00047361 | |||||||||
| RNASeq_FPKM (74) | |||||||||
| GO_annotation (22) | |||||||||
| Ortholog (41) | |||||||||
| Paralog | WBGene00004051 | Caenorhabditis elegans | From_analysis | TreeFam | |||||
| Inparanoid_8 | |||||||||
| Panther | |||||||||
| WormBase-Compara | |||||||||
| Structured_description | Concise_description | parg-2 (formerly known as pme-4) encodes a poly(ADP-ribose) glycohydrolase (PARG) orthologous to human PARG (OMIM:603501) and paralogous to PARG-1; PARG-2 exhibits poly(ADP-ribose) glycohydrolase activity in vitro, and is required in vivo for normal resistance to ionizing radiation; PARG-2 is primarily expressed in the cytoplasm of nerve cells in the head and tail, and also in embryos; neuronal expression of PARG-2 may reflect a requirement for PARG in preventing neurodegeneration like that seen in Drosophila. | Paper_evidence | WBPaper00005600 | |||||
| WBPaper00028953 | |||||||||
| WBPaper00029104 | |||||||||
| Curator_confirmed | WBPerson1843 | ||||||||
| WBPerson567 | |||||||||
| Date_last_updated | 14 Nov 2014 00:00:00 | ||||||||
| Automated_description | Enables poly(ADP-ribose) glycohydrolase activity. Involved in nucleotide-sugar metabolic process and response to gamma radiation. Located in cytoplasm. Expressed in head neurons and tail neurons. Is an ortholog of human BPHL (biphenyl hydrolase like) and PARG (poly(ADP-ribose) glycohydrolase). | Paper_evidence | WBPaper00065943 | ||||||
| Curator_confirmed | WBPerson324 | ||||||||
| WBPerson37462 | |||||||||
| Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||||
| Date_last_updated | 29 Nov 2023 00:00:00 | ||||||||
| Molecular_info (4) | |||||||||
| Experimental_info | RNAi_result | WBRNAi00013332 | Inferred_automatically | RNAi_primary | |||||
| WBRNAi00033743 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00016298 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00065517 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00049464 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00065516 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00102083 | Inferred_automatically | RNAi_primary | |||||||
| Expr_pattern | Expr4510 | ||||||||
| Expr1016211 | |||||||||
| Expr1153191 | |||||||||
| Expr2014733 | |||||||||
| Expr2032967 | |||||||||
| Drives_construct | WBCnstr00004939 | ||||||||
| WBCnstr00037944 | |||||||||
| Construct_product | WBCnstr00037944 | ||||||||
| Microarray_results (17) | |||||||||
| Expression_cluster (263) | |||||||||
| Interaction | WBInteraction000253282 | ||||||||
| WBInteraction000580252 | |||||||||
| Map_info | Map | IV | Position | 3.95647 | Error | 0.001836 | |||
| Positive | Positive_clone | H23L24 | Inferred_automatically | From CDS info | |||||
| From sequence, transcript, pseudogene data | |||||||||
| Mapping_data | Multi_point | 4592 | |||||||
| 4940 | |||||||||
| Pseudo_map_position | |||||||||
| Reference (11) | |||||||||
| Remark | Sequence connection via email from [Desnoyers S], [krb 020729] | ||||||||
| Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | ||||||||
| Method | Gene |
