WormBase Tree Display for Gene: WBGene00003508

WBGene00003508 Evidence: Person_evidence: WBPerson490
  SMap: S_parent: Sequence: B0379
  Identity: Version: 2
    Name: CGC_name: mut-16 Person_evidence: WBPerson261
      Sequence_name: B0379.3
      Molecular_name: B0379.3a
        B0379.3a.1
        CE40346
        B0379.3b
        CE40347
        B0379.3b.1
      Other_name: pqn-3 Person_evidence: WBPerson490
        rde-6 Paper_evidence: WBPaper00036036
        CELE_B0379.3 Accession_evidence: NDB BX284601
      Public_name: mut-16
    DB_info: Database: AceView gene 1K661
        WormQTL gene WBGene00003508
        WormFlux gene WBGene00003508
        NDB locus_tag CELE_B0379.3
        NCBI gene 172873
        RefSeq protein NM_060259.7
            NM_060260.9
        TREEFAM TREEFAM_ID TF319090
        TrEMBL UniProtAcc O62011
            Q9U3S5
        UniProt_GCRP UniProtAcc O62011
    Species: Caenorhabditis elegans
    History: Version_change: 1 07 Apr 2004 11:29:32 WBPerson1971 Event: Imported: Initial conversion from geneace
        2 16 Oct 2013 10:12:26 WBPerson2970 Name_change: Other_name: rde-6
    Status: Live
  Gene_info: Biotype: SO:0001217
    Gene_class: mut
    Allele: WBVar00601255 Inferred_automatically: From strain object: GR1823
          From strain object: JK3826
      WBVar02158887
      WBVar02158929
      WBVar00343287
      WBVar00343288
      WBVar00343289
      WBVar00343290
      WBVar00343291
      WBVar00343292
      WBVar00343293
      WBVar00343294
      WBVar00343295
      WBVar00343296
      WBVar00343297
      WBVar01499739
      WBVar00156382
      WBVar00156383
      WBVar00156384
      WBVar02150163
      WBVar00664693
      WBVar00664694
      WBVar00664695
      WBVar00664696
      WBVar00664697
      WBVar00664698
      WBVar00664699
      WBVar00664700
      WBVar00664701
      WBVar00664702
      WBVar00664703
      WBVar00239325
      WBVar00239326
      WBVar00664704
      WBVar00664705
      WBVar00239327
      WBVar00664706
      WBVar00252356
      WBVar00239329
      WBVar00664707
      WBVar00664708
      WBVar00664709
      WBVar01499045
      WBVar00664710
      WBVar00664711
      WBVar00239333
      WBVar00664712
      WBVar00664713
      WBVar00664714
      WBVar01499786
      WBVar00664715
      WBVar00664716
      WBVar00664717
      WBVar00664718
      WBVar01499054
      WBVar00664719
      WBVar00664720
      WBVar00664721
      WBVar00664722
      WBVar00090972
      WBVar01497609
      WBVar02073717
      WBVar01910239
      WBVar01343345
      WBVar02128316
      WBVar02128317
      WBVar02128318
      WBVar01343356
      WBVar01343367
      WBVar01498959
    Possibly_affected_by: WBVar02152952
      WBVar02153070
      WBVar02153071
    Strain: WBStrain00022637
      WBStrain00028973
      WBStrain00028974
      WBStrain00007950
      WBStrain00040773
    RNASeq_FPKM (74)
    GO_annotation: 00036800
      00036801
      00036802
      00036803
      00036804
      00036805
      00036806
      00036807
      00036808
    Ortholog (17)
    Structured_description: Concise_description: mut-16 encodes a glutamine/asparagine (Q/N)-rich domain-containing protein that lacks obvious homologs outside of other nematode species; MUT-16 activity is required for RNA-mediated interference (RNAi), transgene silencing in germ-line and somatic tissues, and for maintaining low levels of transposon mobilization; MUT-16 is thus predicted to play a role in chromatin organizataion and/or regulation of gene expression. Paper_evidence: WBPaper00005068
            WBPaper00005423
            WBPaper00012788
            WBPaper00012830
            WBPaper00012882
            WBPaper00012897
            WBPaper00013003
          Curator_confirmed: WBPerson1843
          Date_last_updated: 17 Jun 2004 00:00:00
      Automated_description: Involved in obsolete negative regulation of transposition, DNA-mediated; regulatory ncRNA-mediated post-transcriptional gene silencing; and siRNA processing. Located in mutator focus and nucleus. Expressed in several structures, including germ cell; germ line; and somatic cell. Paper_evidence: WBPaper00065943
          Curator_confirmed: WBPerson324
            WBPerson37462
          Inferred_automatically: This description was generated automatically by a script based on data from the WS291 version of WormBase
          Date_last_updated: 29 Nov 2023 00:00:00
  Molecular_info: Corresponding_CDS: B0379.3a
      B0379.3b
    Corresponding_CDS_history: B0379.3a:wp77
      B0379.3a:wp162
      B0379.3b:wp77
      B0379.3b:wp162
    Corresponding_transcript: B0379.3a.1
      B0379.3b.1
    Associated_feature: WBsf976551
      WBsf976552
      WBsf976553
      WBsf976554
      WBsf976555
      WBsf976556
      WBsf984908
      WBsf218389
  Experimental_info: RNAi_result (17)
    Expr_pattern: Expr10153
      Expr11747
      Expr14750
      Expr1016894
      Expr1031604
      Expr1143159
      Expr2013831
      Expr2032071
    Drives_construct: WBCnstr00014702
      WBCnstr00019234
      WBCnstr00041416
      WBCnstr00042129
    Construct_product: WBCnstr00014702
      WBCnstr00042129
    Regulate_expr_cluster: WBPaper00059605:mut-16(pk710)_downregulated
      WBPaper00059605:mut-16(pk710)_upregulated
      WBPaper00059605:MUT-16_interacting
    Microarray_results (20)
    Expression_cluster (111)
    Interaction (250)
    Anatomy_function: WBbtf1091
      WBbtf1092
    WBProcess: WBbiopr:00000057
  Map_info: Map: I Position: 4.60801 Error: 0.009888
    Positive: Positive_clone: B0379 Inferred_automatically: From CDS info
            From sequence, transcript, pseudogene data
    Pseudo_map_position
  Reference (41)
  Remark: Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. CGC_data_submission
  Method: Gene