hyl-1 encodes a ceramide synthase orthologous to Saccharomyces cerevisiae Lag1p (longevity assurance gene), a protein preferentially expressed in young yeasts; by homology, HYL-1 is predicted to have several possible functions, including regulation of lipid, particularly ceramide, biosynthesis, regulation of lipid transport, and regulation of protein translocation in the endoplasmic reticulum.
Predicted to enable sphingosine N-acyltransferase activity. Involved in regulation of locomotion. Located in axon. Expressed in motor neurons. Is an ortholog of human CERS6 (ceramide synthase 6).
Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC.