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WormBase Tree Display for Gene: WBGene00000496

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Name Class

WBGene00000496SMapS_parentSequenceT25G3
IdentityVersion2
NameCGC_namechs-1Person_evidenceWBPerson50
Sequence_nameT25G3.2
Molecular_nameT25G3.2
T25G3.2.1
CE39183
T25G3.2.2
Other_namechi-1CGC_data_submission
chs-2
CELE_T25G3.2Accession_evidenceNDBBX284601
Public_namechs-1
DB_infoDatabase (12)
SpeciesCaenorhabditis elegans
HistoryVersion_change107 Apr 2004 11:29:21WBPerson1971EventImportedInitial conversion from geneace
205 Jul 2004 10:20:16WBPerson1971Name_changeCGC_namechs-1
StatusLive
Gene_infoBiotypeSO:0001217
Gene_classchs
AlleleWBVar00092388Inferred_automaticallyFrom strain object: RB1189
WBVar02072860
WBVar00650299
WBVar01432112
WBVar00650300
WBVar00650301
WBVar01432113
WBVar01432114
WBVar00650302
WBVar00650303
WBVar00650304
WBVar00650305
WBVar00650306
WBVar00650307
WBVar00650308
WBVar00650309
WBVar00650310
WBVar00650311
WBVar00650312
WBVar00650313
WBVar00650314
WBVar00650315
WBVar00650316
WBVar00650317
WBVar00650318
WBVar00650319
WBVar00650320
WBVar00650321
WBVar00650322
WBVar00650323
WBVar00650324
WBVar00650325
WBVar00650326
WBVar00650327
WBVar02151673
WBVar00650328
WBVar00537518
WBVar02127854
WBVar02127855
WBVar02156747
WBVar01345357
WBVar01499786
WBVar01499054
WBVar01420011
WBVar00154387
WBVar00154388
WBVar00338440
WBVar00338441
WBVar00338442
WBVar00338443
WBVar00338444
WBVar00338445
WBVar00338446
WBVar00338447
WBVar00338448
WBVar00338449
WBVar01498959
StrainWBStrain00031890
RNASeq_FPKM (74)
GO_annotation (26)
Contained_in_operonCEOP1400
Ortholog (42)
ParalogWBGene00000497Caenorhabditis elegansFrom_analysisWormBase-Compara
Structured_descriptionConcise_descriptionchs-1 encodes a chitin synthase, paralogous to CHS-2; chs-1 is requiredfor embryonic chitin synthesis, eggshell synthesis and osmoticintegrity, error-free chromosomal segregation during meiosis, polar bodyextrusion, association of the sperm pronucleus/centrosome complex (SPCC)with the early embryonic cortex, localization of PAR-2 in early embryos,posterior localization of P granules or PIE-1, and pseudocleavage; CHS-1is also, independently of chitin synthesis, required for normallocalization of MBK-2 to cortex and punctae in early embryos; CHS-1 isdispensable for synthesis of pharyngeal cuticle, since chs-1(ok1120)mutants have it normally; CHS-1 localizes to the oocyte plasma membrane and .cell cortexPaper_evidenceWBPaper00004881
WBPaper00006390
WBPaper00012846
WBPaper00026721
WBPaper00028588
WBPaper00029233
WBPaper00031014
WBPaper00035426
Curator_confirmedWBPerson1843
WBPerson567
Date_last_updated16 Nov 2010 00:00:00
Automated_descriptionPredicted to enable chitin synthase activity. Involved in cell wall chitin biosynthetic process; eggshell formation; and positive regulation of protein localization to cell cortex. Located in cell cortex and plasma membrane. Expressed in Psub1.Paper_evidenceWBPaper00065943
Curator_confirmedWBPerson324
WBPerson37462
Inferred_automaticallyThis description was generated automatically by a script based on data from the WS291 version of WormBase
Date_last_updated29 Nov 2023 00:00:00
Molecular_infoCorresponding_CDST25G3.2
Corresponding_CDS_historyT25G3.2:wp149
Corresponding_transcriptT25G3.2.1
T25G3.2.2
Other_sequence (54)
Associated_featureWBsf643461
WBsf643462
WBsf656537
WBsf656538
WBsf218023
WBsf218024
Experimental_infoRNAi_result (17)
Expr_patternExpr3655
Expr4906
Expr11042
Expr14401
Expr1011456
Expr1030292
Expr1157706
Expr2009999
Expr2028240
Drives_constructWBCnstr00011576
WBCnstr00037497
Construct_productWBCnstr00001287
WBCnstr00019030
WBCnstr00037497
Microarray_results (19)
Expression_cluster (168)
Interaction (188)
Map_infoMapIPosition2.13842Error0.012536
PositivePositive_cloneT25G3Inferred_automaticallyFrom sequence, transcript, pseudogene data
Mapping_dataMulti_point4887
5298
Pseudo_map_position
ReferenceWBPaper00004881
WBPaper00010668
WBPaper00010809
WBPaper00026113
WBPaper00026721
WBPaper00027938
WBPaper00028588
WBPaper00029024
WBPaper00030694
WBPaper00031014
WBPaper00031064
WBPaper00031129
WBPaper00035426
WBPaper00036882
WBPaper00037715
WBPaper00041423
WBPaper00045573
WBPaper00046691
WBPaper00047153
WBPaper00052117
WBPaper00058103
WBPaper00062623
WBPaper00064315
RemarkGene was renamed from chi-1 to chs-1 at request of CGC, note that the other name 'chs-2' is from the Brugia malayi ortholog...this ortholog may be renamed in the future to clarify the situation.CGC_data_submission
Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC.CGC_data_submission
MethodGene