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WormBase Tree Display for Gene: WBGene00010778

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Name Class

WBGene00010778SMapS_parentSequenceK11H3
IdentityVersion2
NameCGC_namegpdh-2Person_evidenceWBPerson1851
Sequence_nameK11H3.1
Molecular_name (12)
Other_nameCELE_K11H3.1Accession_evidenceNDBBX284603
Public_namegpdh-2
DB_infoDatabase (14)
SpeciesCaenorhabditis elegans
HistoryVersion_change126 May 2004 16:54:51WBPerson1971EventImportedInitial conversion from CDS class of WS125
212 Sep 2006 10:49:55WBPerson2970Name_changeCGC_namegpdh-2
StatusLive
Gene_infoBiotypeSO:0001217
Gene_classgpdh
AlleleWBVar00100959
WBVar01939584
WBVar01939585
WBVar01500260
WBVar01939586
WBVar00305424
WBVar00852909
WBVar00852910
WBVar00852911
WBVar00852912
WBVar00852913
WBVar00852914
WBVar01267317
WBVar00852915
WBVar00852916
WBVar00852917
WBVar00852918
WBVar00852919
WBVar00852920
WBVar00852921
WBVar00852922
WBVar00852923
WBVar00852924
WBVar00852925
WBVar00852926
WBVar00852927
WBVar00852928
WBVar00852929
WBVar00852930
WBVar00852931
WBVar00852932
WBVar00852933
WBVar00852934
WBVar00852935
WBVar00852936
WBVar00852937
WBVar00852938
WBVar00852939
WBVar02086618
WBVar00852940
WBVar00852941
WBVar01499774
WBVar00598650
WBVar01827719
WBVar01827720
WBVar00088235
WBVar00092936
WBVar01490782
WBVar01567238
WBVar00318426
WBVar00178198
WBVar00178199
WBVar00178200
WBVar00406163
WBVar00258865
WBVar00406164
WBVar00406165
WBVar00406166
WBVar00237023
WBVar00406167
WBVar00406168
WBVar00406169
WBVar00406170
WBVar00406171
WBVar00406172
WBVar00406173
WBVar00406174
WBVar02085415
WBVar01629527
WBVar00298474
WBVar00322127
WBVar00215661
WBVar01447719
WBVar02069657
WBVar01447720
WBVar00215663
WBVar00215664
StrainWBStrain00003775
WBStrain00032179
WBStrain00048030
RNASeq_FPKM (74)
GO_annotation (26)
Contained_in_operonCEOP3795
Ortholog (48)
ParalogWBGene00009824Caenorhabditis elegansFrom_analysisTreeFam
Panther
WormBase-Compara
Structured_descriptionConcise_descriptiongpdh-2 encodes one of two C. elegans glycerol 3-phosphate dehydrogenases; although loss of gpdh-2 activity via large-scale RNAi screens results in no obvious defects, expression of a gpdh-2 cDNA in Saccharomyces cerevisiae hog1 mutants is able to rescue the high osmolarity-sensitive growth phenotype of these mutants, suggesting that gpdh-2 encodes a functional glycerol 3-phosphate dehydrogenase.Paper_evidenceWBPaper00003607
Curator_confirmedWBPerson1843
Date_last_updated11 Dec 2006 00:00:00
Automated_descriptionPredicted to enable glycerol-3-phosphate dehydrogenase (quinone) activity and glycerol-3-phosphate dehydrogenase [NAD(P)+] activity. Involved in intracellular accumulation of glycerol. Predicted to be located in cytosol. Predicted to be part of glycerol-3-phosphate dehydrogenase complex. Expressed in excretory cell and hypodermis. Human ortholog(s) of this gene implicated in Brugada syndrome 2. Is an ortholog of human GPD1 (glycerol-3-phosphate dehydrogenase 1) and GPD1L (glycerol-3-phosphate dehydrogenase 1 like).Paper_evidenceWBPaper00065943
Curator_confirmedWBPerson324
WBPerson37462
Inferred_automaticallyThis description was generated automatically by a script based on data from the WS291 version of WormBase
Date_last_updated29 Nov 2023 00:00:00
Disease_infoPotential_modelDOID:0110219Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:28956)
Molecular_infoCorresponding_CDSK11H3.1a
K11H3.1b
K11H3.1c
K11H3.1d
Corresponding_CDS_historyK11H3.1:wp85
Corresponding_transcriptK11H3.1a.1
K11H3.1b.1
K11H3.1c.1
K11H3.1d.1
Other_sequenceMIC05690_1
FG583129.1
FK806244.1
TV00145
Tcol_isotig05517
RS10010
AYC03638_1
BU087933.1
FC544024.1
Oden_isotig05101
EX557361.1
FC546041.1
ACC18422_1
FK808678.1
FF679816.1
RS10310
FC550121.1
MC04651
EX009578.1
FF679626.1
FK807955.1
AE02469
FK803885.1
EY469729.1
RSC03254_1
MCC00282_1
ACC00574_1
HBC20271_1
BXC01368_1
GO239026.1
Name_isotig02417
GO238890.1
Oden_isotig05111
EX559984.1
Tcol_isotig05519
CSC01799_1
AYC02482_1
CBC04363_1
FE913163.1
GO238902.1
RSC04575_1
EX007054.1
EY465713.1
ACC06834_1
Oden_isotig05104
GO238964.1
FF681946.1
HG02431
GO239002.1
EX537354.1
Oden_isotig05108
ASC38078_1
Tcir_isotig10062
GO238878.1
EX562357.1
EY473349.1
JI168777.1
FK804507.1
GO238970.1
EW743113.1
EX547536.1
EY462092.1
HBC03506_1
EY462832.1
CRC05037_1
NAC00419_1
GO239030.1
GO238997.1
EX565384.1
FC543226.1
EY468189.1
FK805030.1
FC547880.1
Oden_isotig05109
EX565201.1
EX563150.1
Tcol_isotig05518
Oden_isotig05110
GO238914.1
EX563033.1
FC554626.1
Oden_isotig05100
AE03722
Tcol_isotig05520
BXC00038_1
GO238892.1
GO238917.1
ES744009.1
CSC01332_1
ACC19012_1
FC544392.1
EX015073.1
GO251483.1
PVC01609_1
PPC05272_1
MC00107
ACC27730_1
ES672851.1
OOC01707_1
FC553460.1
ACC26554_1
EY463085.1
EX565340.1
FK806950.1
FD516766.1
EX560747.1
GO238905.1
CV200936.1
GRC05459_1
Oden_isotig05103
JI171360.1
GR11238
FF681648.1
FC545627.1
BU087647.1
EX556342.1
FK809514.1
BUC00939_1
FK808055.1
GO252366.1
ACC12855_1
EX555685.1
ACC15473_1
BU666257.1
ACC16122_1
AE04194
FC546271.1
GO238975.1
Acan_isotig03556
Oden_isotig05105
EY466041.1
EW743873.1
BU665939.1
GO238915.1
FC555247.1
CR02308
TVC00835_1
EX914852.1
EY463769.1
FF681834.1
FK804456.1
SC00357
GO239004.1
FD517020.1
FF679520.1
EY462579.1
ES672860.1
EX565118.1
HGC05995_1
MI05971
Oden_isotig05102
PPC07545_1
EW743272.1
PPC17466_1
BXC01358_1
MI02091
Oden_isotig05107
JI172093.1
GO238950.1
GO238904.1
GO238980.1
CJC13854_1
DN153032.1
Acan_isotig11738
BXC00857_1
JO471647.1
GO238985.1
GO238895.1
Hbac_isotig01619
Dviv_isotig23680
Oden_isotig05106
FC552297.1
FF679326.1
Acan_isotig03555
GR978767.1
EY469224.1
GO238953.1
EY467748.1
BU088359.1
Associated_feature (14)
Experimental_infoRNAi_resultWBRNAi00034302Inferred_automaticallyRNAi_primary
WBRNAi00092280Inferred_automaticallyRNAi_primary
WBRNAi00050633Inferred_automaticallyRNAi_primary
WBRNAi00017038Inferred_automaticallyRNAi_primary
WBRNAi00092279Inferred_automaticallyRNAi_primary
WBRNAi00006047Inferred_automaticallyRNAi_primary
Expr_patternExpr3987
Expr6392
Expr1018067
Expr1034717
Expr1154341
Expr2012210
Expr2030446
Drives_constructWBCnstr00004195
WBCnstr00011798
WBCnstr00031154
Construct_productWBCnstr00031154
Microarray_results (34)
Expression_cluster (151)
Interaction (111)
Map_infoMapIIIPosition1.12662Error0.001222
PositivePositive_cloneK11H3Inferred_automaticallyFrom sequence, transcript, pseudogene data
Pseudo_map_position
Reference (17)
RemarkMap position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC.CGC_data_submission
MethodGene