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WormBase Tree Display for Gene: WBGene00003495

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Name Class

WBGene00003495SMapS_parentSequenceT22E5
IdentityVersion1
NameCGC_namemup-2Person_evidenceWBPerson1052
Sequence_nameT22E5.5
Molecular_nameT22E5.5
T22E5.5.1
CE04994
Other_nametnt-1
CELE_T22E5.5Accession_evidenceNDBBX284606
Public_namemup-2
DB_infoDatabase (11)
SpeciesCaenorhabditis elegans
HistoryVersion_change107 Apr 2004 11:29:32WBPerson1971EventImportedInitial conversion from geneace
StatusLive
Gene_infoBiotypeSO:0001217
Gene_classmup
AlleleWBVar00144763Inferred_automaticallyFrom strain object: EE31
From strain object: EE66
From strain object: EE67
WBVar00274914
WBVar00033261
WBVar01154033
WBVar01154034
WBVar01154035
WBVar01154036
WBVar01154037
WBVar01154038
WBVar01154039
WBVar01154040
WBVar01154041
WBVar01154042
WBVar01154043
WBVar01154044
WBVar01154045
WBVar01154046
WBVar01154047
WBVar01154048
WBVar01881337
WBVar01154049
WBVar01154050
WBVar01469344
WBVar00506077
WBVar00506078
WBVar00506079
WBVar00506080
WBVar01500067
Legacy_information[C.elegansII] e2346ts : embryonic temp-shift leads to lethal mispositioning and deformity of body-wall muscle; larval temp-shift leads to sterility, defects in oviduct muscle. OA1: up1 (non-conditional, lethal with arrest as kinked larva; probable null, nonsense mutation). Cloned: encodes troponin T homolog. [EE; UG]
StrainWBStrain00006650
WBStrain00006651
WBStrain00006652
RNASeq_FPKM (74)
GO_annotation (13)
Ortholog (36)
ParalogWBGene00006587Caenorhabditis elegansFrom_analysisInparanoid_8
Panther
WormBase-Compara
WBGene00006589Caenorhabditis elegansFrom_analysisPanther
WormBase-Compara
WBGene00006588Caenorhabditis elegansFrom_analysisPanther
WormBase-Compara
Structured_descriptionConcise_descriptionmup-2 encodes the muscle contractile protein troponin T ( TnT ) homologous to vertebrate and invertebrate TnT and contains an invertebrate- specific COOH -terminal tail; mup-2 affects embryonic body wall muscle cell contraction, sarcomere organization, cell positioning, regulated muscle contraction in larval and adult body wall muscle, epidermal morphogenesis, and is required for proper function of the hermaphrodite nonstriated oviduct myoepithelial sheath, proper growth, and fertility.Paper_evidenceWBPaper00002414
WBPaper00003294
WBPaper00006395
Curator_confirmedWBPerson48
Date_last_updated11 Mar 2005 00:00:00
Automated_descriptionPredicted to enable tropomyosin binding activity. Involved in several processes, including axonal fasciculation; muscle structure development; and ovulation. Predicted to be part of troponin complex. Human ortholog(s) of this gene implicated in several diseases, including distal arthrogryposis type 2B2; intrinsic cardiomyopathy (multiple); and nemaline myopathy (multiple). Is an ortholog of human TNNT1 (troponin T1, slow skeletal type); TNNT2 (troponin T2, cardiac type); and TNNT3 (troponin T3, fast skeletal type).Paper_evidenceWBPaper00065943
Curator_confirmedWBPerson324
WBPerson37462
Inferred_automaticallyThis description was generated automatically by a script based on data from the WS291 version of WormBase
Date_last_updated29 Nov 2023 00:00:00
Disease_infoPotential_model (14)
Molecular_infoCorresponding_CDST22E5.5
Corresponding_transcriptT22E5.5.1
Other_sequenceAA610992.1
ALC00525_1
JO467824.1
BU586403.1
BMC12178_1
ACC03796_2
RS07461
HSC00418_1
GRC00282_1
FG974091.1
FG584381.1
CJC09642_1
BE720906.1
AI444915.1
TSC01054_1
JI168224.1
BU586171.1
CGC00871_1
ES561456.1
AI205465.1
DA03422
ES273495.1
CJC10511_1
AI124216.1
BXC03149_1
HS00244
FG972995.1
CR03852
HS00757
BE346054.1
EX536240.1
AYC02675_1
FK801927.1
GW406771.1
FK803472.1
PPC00164_1
MJ00472
DAC02009_1
EX551045.1
MHC02489_1
MC00708
ES273044.1
CK725966.1
FG347795.1
TX00320
TS01181
CK725536.1
JI483529.1
FK806788.1
AI130173.1
CK855496.1
ES290990.1
FE597068.1
Tcir_isotig10663
SR02893
Tcir_isotig13899
DN190560.1
AI815322.1
GW413115.1
AW980283.1
NBC00437_1
MH02251
AAC00680_1
GW412583.1
MI02592
BXC03621_1
EL887853.1
ZP00166
MHC01364_1
AA917119.1
CR01817
GR14184
BMC00135_1
CJC03009_1
FE597262.1
FG974989.1
ACC03998_1
JI246635.1
AM744862.1
ASC16100_1
BE346074.1
AS00533
ZPC00085_1
FG971155.1
AA293911.1
JO471660.1
AS12305
ES567179.1
PTC02386_1
TCC00639_1
FG585776.1
FE597205.1
JI168759.1
NB08046
MJC02017_1
FG350470.1
DA05176
MIC00101_1
TSC08067_1
ACC29082_1
GW412643.1
FG976558.1
HO243985.1
CBC00369_1
MC03608
BUC00886_1
CRC01928_1
EX542815.1
NAC02202_1
BU088428.1
DAC01067_1
BE491756.1
ASC00867_1
EX537532.1
BE346007.1
TX00405
FC811945.1
FC549368.1
EY473465.1
CK725974.1
FE597381.1
Tcol_isotig09653
ASC00178_1
PVC02136_1
RSC04146_1
MI01025
EY463361.1
AE03411
SRC00656_1
ES563928.1
Tcol_isotig09654
AS01116
ES567736.1
AJ419175.1
FE597081.1
MIC00101_2
BXC01604_1
AS04128
EX915303.1
BUC00191_1
Associated_featureWBsf654064
WBsf670625
WBsf670626
WBsf1005570
WBsf1005571
WBsf1023097
WBsf237478
WBsf237479
WBsf237480
Experimental_infoRNAi_result (21)
Expr_patternExpr1026876
Expr1031599
Expr1157386
Expr2013825
Expr2032065
Drives_constructWBCnstr00036087
Construct_productWBCnstr00036087
Microarray_results (23)
Expression_cluster (248)
Interaction (72)
WBProcessWBbiopr:00000006
WBbiopr:00000067
Map_infoMapXPosition-2.91797Error0.002167
Well_ordered
PositivePositive_cloneR04A4
T22E5Inferred_automaticallyFrom sequence, transcript, pseudogene data
Mapping_dataMulti_point3386
3694
3958
Reference (39)
MethodGene