WormBase Tree Display for Gene: WBGene00012186

WBGene00012186 SMap: S_parent: Sequence: W01F3
  Identity: Version: 3
    Name: CGC_name: mlt-11 Person_evidence: WBPerson545
            WBPerson3379
      Sequence_name: W01F3.3
      Molecular_name (24)
      Other_name: phi-36 Person_evidence: WBPerson2582
        CELE_W01F3.3 Accession_evidence: NDB BX284605
      Public_name: mlt-11
    DB_info: Database: AceView gene 5V147
        WormQTL gene WBGene00012186
        WormFlux gene WBGene00012186
        NDB locus_tag CELE_W01F3.3
        Panther gene CAEEL|WormBase=WBGene00012186|UniProtKB=B9WRT9
          family PTHR10083
        NCBI gene 180352
        RefSeq protein NM_001270012.3
            NM_001270011.3
            NM_001270009.3
            NM_001270014.3
            NM_001270015.4
            NM_001270013.3
            NM_001270016.3
            NM_001270010.3
        TREEFAM TREEFAM_ID TF315349
        TrEMBL UniProtAcc O45881
            C1P660
            C1P659
            B9WRT9
            H9G334
            H9G335
            H9G336
            C1P658
        UniProt_GCRP UniProtAcc B9WRT9
    Species: Caenorhabditis elegans
    History: Version_change: 1 26 May 2004 16:54:53 WBPerson1971 Event: Imported: Initial conversion from CDS class of WS125
        2 17 Mar 2005 13:54:35 WBPerson2970 Name_change: Other_name: phi-36
        3 28 Jul 2005 14:22:15 WBPerson2970 Name_change: CGC_name: mlt-11
    Status: Live
  Gene_info: Biotype: SO:0001217
    Gene_class: mlt
    Allele: WBVar00240357
      WBVar00240359
      WBVar01108633
      WBVar00073752
      WBVar01108634
      WBVar00073753
      WBVar00073754
      WBVar01108635
      WBVar01756566
      WBVar00073755
      WBVar01756567
      WBVar01108636
      WBVar00073756
      WBVar01756568
      WBVar01108637
      WBVar01756569
      WBVar01108638
      WBVar01756570
      WBVar01108639
      WBVar01756571
      WBVar02138496
      WBVar01108640
      WBVar01108641
      WBVar01756572
      WBVar02138497
      WBVar01499709
      WBVar01108642
      WBVar01756573
      WBVar02138498
      WBVar01756574
      WBVar01108643
      WBVar00105810
      WBVar01756575
      WBVar01108644
      WBVar01108645
      WBVar01756576
      WBVar01756577
      WBVar00068019
      WBVar00490865
      WBVar01108646
      WBVar01108647
      WBVar00490866
      WBVar01108648
      WBVar00490867
      WBVar00490868
      WBVar01108649
      WBVar00490869
      WBVar01108650
      WBVar01829903
      WBVar01108651
      WBVar00490870
      WBVar00490871
      WBVar01108652
      WBVar01599999
      WBVar01108653
      WBVar00490872
      WBVar01600000
      WBVar01108654
      WBVar00490873
      WBVar00490874
      WBVar01600001
      WBVar01108655
      WBVar01600002
      WBVar00490875
      WBVar01108656
      WBVar01941337
      WBVar01108657
      WBVar01600003
      WBVar00490876
      WBVar01600004
      WBVar00490877
      WBVar01108658
      WBVar01600005
      WBVar00490878
      WBVar01108659
      WBVar01600006
      WBVar00490879
      WBVar01108660
      WBVar01600007
      WBVar00490880
      WBVar01108661
      WBVar01108662
      WBVar00490881
      WBVar00490882
      WBVar01108663
      WBVar01108664
      WBVar00490883
      WBVar01108665
      WBVar00490884
      WBVar00490885
      WBVar01108666
      WBVar01108667
      WBVar00490886
      WBVar00490887
      WBVar01108668
      WBVar00490888
      WBVar01108669
      WBVar01108670
      WBVar00490889
      WBVar01108671
      WBVar00490890
      WBVar00490891
      WBVar01108672
      WBVar00490892
      WBVar01108673
      WBVar01108674
      WBVar00490893
      WBVar01108675
      WBVar00490894
      WBVar01108676
      WBVar00490895
      WBVar01108677
      WBVar00490896
      WBVar01108678
      WBVar00490897
      WBVar01108679
      WBVar00490898
      WBVar01108680
      WBVar00490899
      WBVar00490900
      WBVar01108681
      WBVar01108682
      WBVar00490901
      WBVar01108683
      WBVar00490902
      WBVar00490903
      WBVar01108684
      WBVar01689898
      WBVar01108685
      WBVar00490904
      WBVar00490905
      WBVar01108686
      WBVar00490906
      WBVar01108687
      WBVar01108688
      WBVar01108689
      WBVar00603308
      WBVar01108690
      WBVar00603309
      WBVar00603310
      WBVar01108691
      WBVar00603311
      WBVar01108692
      WBVar01108693
      WBVar00603314
      WBVar00302325
      WBVar01108694
      WBVar01108695
      WBVar01108696
      WBVar01108697
      WBVar01108698
      WBVar01108699
      WBVar01108700
      WBVar01108701
      WBVar01108702
      WBVar02063431
      WBVar01526374
      WBVar01108703
      WBVar01108704
      WBVar01108705
      WBVar01926653
      WBVar01108706
      WBVar01108707
      WBVar01108708
      WBVar01108709
      WBVar01108710
      WBVar01108711
      WBVar01108712
      WBVar01108713
      WBVar00238622
      WBVar01108714
      WBVar01108715
      WBVar01108716
      WBVar01108717
      WBVar02026424
      WBVar01499446
      WBVar00246564
      WBVar01500000
      WBVar01544377
      WBVar01914128
      WBVar01914129
      WBVar02070363
      WBVar01498549
      WBVar01486039
      WBVar01877904
      WBVar01877905
      WBVar01877906
      WBVar01877907
      WBVar01877908
      WBVar01877909
      WBVar01877910
      WBVar01499299
      WBVar00229273
      WBVar02050373
      WBVar02050374
      WBVar01108623
      WBVar01108624
      WBVar01108625
      WBVar01108626
      WBVar01108627
      WBVar01498958
      WBVar01108628
      WBVar00073747
      WBVar01108629
      WBVar00073748
      WBVar00073749
      WBVar01108630
      WBVar01108631
      WBVar00073750
      WBVar01108632
      WBVar00073751
    RNASeq_FPKM (74)
    GO_annotation: 00006591
      00006592
      00006593
      00006594
      00119363
    Ortholog: WBGene00063539 Caenorhabditis remanei From_analysis: OMA
            TreeFam
            Inparanoid_8
            WormBase-Compara
      WBGene00028044 Caenorhabditis briggsae From_analysis: Hillier-set
            OrthoMCL
            OMA
            Inparanoid_8
            WormBase-Compara
      WBGene00157306 Caenorhabditis brenneri From_analysis: TreeFam
      WBGene00137923 Caenorhabditis japonica From_analysis: TreeFam
            Inparanoid_8
            WormBase-Compara
      WBGene00145314 Caenorhabditis brenneri From_analysis: TreeFam
            WormBase-Compara
      WBGene00157758 Caenorhabditis brenneri From_analysis: TreeFam
      WBGene00057945 Caenorhabditis remanei From_analysis: TreeFam
      WBGene00226370 Brugia malayi From_analysis: WormBase-Compara
      CBOVI.g2223 Caenorhabditis bovis From_analysis: WormBase-Compara
      CSP21.g4681 Caenorhabditis parvicauda From_analysis: WormBase-Compara
      CSP26.g13328 Caenorhabditis zanzibari From_analysis: WormBase-Compara
      CSP28.g5759 Caenorhabditis panamensis From_analysis: WormBase-Compara
      CSP29.g19227 Caenorhabditis becei From_analysis: WormBase-Compara
      CSP31.g3466 Caenorhabditis uteleia From_analysis: WormBase-Compara
      CSP32.g13679 Caenorhabditis sulstoni From_analysis: WormBase-Compara
      CSP38.g12696 Caenorhabditis quiockensis From_analysis: WormBase-Compara
      CSP39.g9380 Caenorhabditis waitukubuli From_analysis: WormBase-Compara
      CSP40.g3825 Caenorhabditis tribulationis From_analysis: WormBase-Compara
      Cang_2012_03_13_00003.g302 Caenorhabditis angaria From_analysis: WormBase-Compara
      Cni-mlt-11 Caenorhabditis nigoni From_analysis: WormBase-Compara
      Csp11.Scaffold630.g21826 Caenorhabditis tropicalis From_analysis: WormBase-Compara
      Csp5_scaffold_01803.g23231 Caenorhabditis sinica From_analysis: WormBase-Compara
      FL83_18038 Caenorhabditis latens From_analysis: WormBase-Compara
      OTIPU.nOt.2.0.1.g00088 Oscheius tipulae From_analysis: WormBase-Compara
      Sp34_50401300 Caenorhabditis inopinata From_analysis: WormBase-Compara
      chrV_pilon.g18147 Caenorhabditis elegans From_analysis: WormBase-Compara
      WBGene00244076 Onchocerca volvulus From_analysis: WormBase-Compara
      WBGene00103601 Pristionchus pacificus From_analysis: WormBase-Compara
      WBGene00263853 Strongyloides ratti From_analysis: WormBase-Compara
    Paralog (28)
    Structured_description: Concise_description: mlt-11 encodes one of 13 C. elegans proteins related to the mammalian Tissue Factor Pathway Inhibitors (TFPIs), serine protease inhibitors that function in blood coagulation (OMIM:152310); in C. elegans, genetic analysis indicates that mlt-11 is required for proper molting and, likely, for proper spatial and/or temporal regulation of proteolysis during the molting cycle; a mlt-11::gfp promoter fusion is expressed mid-way through each larval stage in the hypodermis including the hyp7 syncytium, the lateral seam cells (at larval-to-larval molts) and head and tail hypodermis; mlt-11 expression appears to be positively regulated by NHR-23 and LIN-14. Paper_evidence: WBPaper00026763
            WBPaper00026952
          Curator_confirmed: WBPerson1843
          Date_last_updated: 22 Jan 2009 00:00:00
      Automated_description: Predicted to enable serine-type endopeptidase inhibitor activity. Predicted to be located in extracellular space. Expressed in hypodermis. Paper_evidence: WBPaper00065943
          Curator_confirmed: WBPerson324
            WBPerson37462
          Inferred_automatically: This description was generated automatically by a script based on data from the WS291 version of WormBase
          Date_last_updated: 29 Nov 2023 00:00:00
  Molecular_info: Corresponding_CDS: W01F3.3a
      W01F3.3b
      W01F3.3c
      W01F3.3d
      W01F3.3e
      W01F3.3f
      W01F3.3g
      W01F3.3h
    Corresponding_CDS_history: W01F3.3:wp158
    Corresponding_transcript: W01F3.3a.1
      W01F3.3b.1
      W01F3.3c.1
      W01F3.3d.1
      W01F3.3e.1
      W01F3.3f.1
      W01F3.3g.1
      W01F3.3h.1
    Other_sequence (47)
    Associated_feature (23)
  Experimental_info: RNAi_result: WBRNAi00066552 Inferred_automatically: RNAi_primary
      WBRNAi00089175 Inferred_automatically: RNAi_primary
      WBRNAi00095752 Inferred_automatically: RNAi_primary
      WBRNAi00026446 Inferred_automatically: RNAi_primary
      WBRNAi00054530 Inferred_automatically: RNAi_primary
      WBRNAi00065007 Inferred_automatically: RNAi_primary
      WBRNAi00066817 Inferred_automatically: RNAi_primary
      WBRNAi00009240 Inferred_automatically: RNAi_primary
      WBRNAi00066739 Inferred_automatically: RNAi_primary
    Expr_pattern: Expr3693
      Expr1011804
      Expr1035388
      Expr1158076
      Expr2013605
      Expr2031838
    Drives_construct: WBCnstr00006890
      WBCnstr00011604
      WBCnstr00030076
    Construct_product: WBCnstr00030076
    Microarray_results (28)
    Expression_cluster (337)
    Interaction (81)
  Map_info: Map: V Position: 25.031 Error: 0.000443
    Positive: Positive_clone: W01F3 Inferred_automatically: From sequence, transcript, pseudogene data
    Pseudo_map_position
  Reference: WBPaper00026952
    WBPaper00038491
    WBPaper00055090
    WBPaper00059378
    WBPaper00061662
    WBPaper00062278
    WBPaper00062715
    WBPaper00062969
    WBPaper00065000
    WBPaper00065560
  Remark: Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. CGC_data_submission
  Method: Gene