WormBase Tree Display for Gene: WBGene00000122

WBGene00000122 SMap: S_parent: Sequence: M18
  Identity: Version: 1
    Name: CGC_name: aly-3 Person_evidence: WBPerson297
            WBPerson4981
      Sequence_name: M18.7
      Molecular_name: M18.7a
        M18.7a.1
        CE06198
        M18.7b
      Other_name: CELE_M18.7 Accession_evidence: NDB BX284604
      Public_name: aly-3
    DB_info: Database: WormQTL gene WBGene00000122
        WormFlux gene WBGene00000122
        NDB locus_tag CELE_M18.7
        Panther gene CAEEL|WormBase=WBGene00000122|UniProtKB=Q21559
          family PTHR19965
        NCBI gene 178157
        RefSeq protein NR_003454.1
            NM_001083228.6
        TREEFAM TREEFAM_ID TF313312
        TrEMBL UniProtAcc Q21559
        UniProt_GCRP UniProtAcc Q21559
        RNAcentral URSid URS0000253FBA
    Species: Caenorhabditis elegans
    History: Version_change: 1 07 Apr 2004 11:29:20 WBPerson1971 Event: Imported: Initial conversion from geneace
    Status: Live
  Gene_info: Biotype: SO:0001217
    Gene_class: aly
    Allele: WBVar02156997
      WBVar02158636
      WBVar01500079
      WBVar01825794
      WBVar00251019
      WBVar01498811
      WBVar01498996
      WBVar01499925
      WBVar00251077
      WBVar01859062
      WBVar01498540
      WBVar00437276
      WBVar01499672
      WBVar02059290
      WBVar02134790
      WBVar00946958
      WBVar00946959
      WBVar00946960
      WBVar00946961
      WBVar00946962
      WBVar00946963
      WBVar00946964
      WBVar00946965
      WBVar00946966
      WBVar01500245
      WBVar00946967
      WBVar00946968
      WBVar01498775
      WBVar00946969
      WBVar00946970
      WBVar00946971
      WBVar01498779
      WBVar00946972
    RNASeq_FPKM (74)
    GO_annotation: 00072102
      00072103
      00072104
      00072105
      00106836
    Contained_in_operon: CEOP4496
    Ortholog: WBGene00028541 Caenorhabditis briggsae From_analysis: OrthoMCL
            OMA
            Inparanoid_8
            WormBase-Compara
      WBGene00075068 Caenorhabditis remanei From_analysis: OMA
            TreeFam
            WormBase-Compara
      WBGene00156774 Caenorhabditis brenneri From_analysis: OMA
            TreeFam
            Inparanoid_8
            WormBase-Compara
      WBGene00145339 Caenorhabditis brenneri From_analysis: OMA
            TreeFam
            Inparanoid_8
            WormBase-Compara
      WBGene00136109 Caenorhabditis japonica From_analysis: OMA
            TreeFam
            Inparanoid_8
            WormBase-Compara
      WBGene00066295 Caenorhabditis remanei From_analysis: Inparanoid_8
            WormBase-Compara
      CBOVI.g11644 Caenorhabditis bovis From_analysis: WormBase-Compara
      CSP21.g3527 Caenorhabditis parvicauda From_analysis: WormBase-Compara
      CSP26.g3197 Caenorhabditis zanzibari From_analysis: WormBase-Compara
      CSP28.g11030 Caenorhabditis panamensis From_analysis: WormBase-Compara
      CSP29.g7726 Caenorhabditis becei From_analysis: WormBase-Compara
      CSP31.g6447 Caenorhabditis uteleia From_analysis: WormBase-Compara
      CSP32.g11033 Caenorhabditis sulstoni From_analysis: WormBase-Compara
      CSP38.g958 Caenorhabditis quiockensis From_analysis: WormBase-Compara
      CSP39.g8790 Caenorhabditis waitukubuli From_analysis: WormBase-Compara
      CSP40.g22653 Caenorhabditis tribulationis From_analysis: WormBase-Compara
      Cni-aly-3 Caenorhabditis nigoni From_analysis: WormBase-Compara
      Csp11.Scaffold448.g1269 Caenorhabditis tropicalis From_analysis: WormBase-Compara
      Csp5_scaffold_00064.g3052 Caenorhabditis sinica From_analysis: WormBase-Compara
      FL83_04857 Caenorhabditis latens From_analysis: WormBase-Compara
      GCK72_014246 Caenorhabditis remanei From_analysis: WormBase-Compara
      OTIPU.nOt.2.0.1.g03166 Oscheius tipulae From_analysis: WormBase-Compara
      Sp34_40238000 Caenorhabditis inopinata From_analysis: WormBase-Compara
      chrIV_pilon.g12006 Caenorhabditis elegans From_analysis: WormBase-Compara
      WBGene00090238 Pristionchus pacificus From_analysis: WormBase-Compara
      WBGene00111598 Pristionchus pacificus From_analysis: WormBase-Compara
      WBGene00116154 Pristionchus pacificus From_analysis: WormBase-Compara
      WBGene00275161 Pristionchus pacificus From_analysis: WormBase-Compara
      WBGene00285690 Trichuris muris From_analysis: WormBase-Compara
      WBGene00298093 Trichuris muris From_analysis: WormBase-Compara
      FB:FBgn0032439 Drosophila melanogaster From_analysis: OrthoFinder
            Panther
            SonicParanoid
      FB:FBgn0010774 Drosophila melanogaster From_analysis: EnsEMBL-Compara
            Hieranoid
            Inparanoid
            OMA
            OrthoFinder
            OrthoInspector
            Panther
            PhylomeDB
            SonicParanoid
      ZFIN:ZDB-GENE-070928-29 Danio rerio From_analysis: EnsEMBL-Compara
            Hieranoid
            Inparanoid
            OrthoFinder
            Panther
            PhylomeDB
      HGNC:19071 Homo sapiens From_analysis: EnsEMBL-Compara
            Hieranoid
            Inparanoid
            OrthoFinder
            Panther
            PhylomeDB
      MGI:1341044 Mus musculus From_analysis: EnsEMBL-Compara
            Hieranoid
            Inparanoid
            OrthoFinder
            Panther
            PhylomeDB
      MGI:1913144 Mus musculus From_analysis: Hieranoid
            Inparanoid
            OrthoFinder
            OrthoInspector
            Panther
            PhylomeDB
      MGI:1918238 Mus musculus From_analysis: EnsEMBL-Compara
            Hieranoid
            Inparanoid
            OrthoFinder
            Panther
      MGI:3649020 Mus musculus From_analysis: EnsEMBL-Compara
            Hieranoid
            Inparanoid
            OrthoFinder
            Panther
      MGI:3782481 Mus musculus From_analysis: EnsEMBL-Compara
            Hieranoid
            Inparanoid
            OrthoFinder
            Panther
            PhylomeDB
      MGI:3782482 Mus musculus From_analysis: EnsEMBL-Compara
            Hieranoid
            Inparanoid
            OrthoFinder
            Panther
      MGI:3782483 Mus musculus From_analysis: EnsEMBL-Compara
            Hieranoid
            Inparanoid
            OrthoFinder
            Panther
      MGI:3782485 Mus musculus From_analysis: EnsEMBL-Compara
            Hieranoid
            Inparanoid
            OrthoFinder
            Panther
      MGI:3782487 Mus musculus From_analysis: EnsEMBL-Compara
            Hieranoid
            Inparanoid
            OrthoFinder
            Panther
      MGI:3782493 Mus musculus From_analysis: EnsEMBL-Compara
            Hieranoid
            Inparanoid
            OrthoFinder
            Panther
            PhylomeDB
      MGI:3782524 Mus musculus From_analysis: EnsEMBL-Compara
            Hieranoid
            Inparanoid
            OrthoFinder
            Panther
            PhylomeDB
      MGI:5434648 Mus musculus From_analysis: EnsEMBL-Compara
            Hieranoid
            Inparanoid
            OrthoFinder
            Panther
            PhylomeDB
      RGD:1594679 Rattus norvegicus From_analysis: EnsEMBL-Compara
            Hieranoid
            Inparanoid
            OrthoFinder
            Panther
    Paralog: WBGene00000120 Caenorhabditis elegans From_analysis: TreeFam
            Inparanoid_8
            Panther
            WormBase-Compara
      WBGene00000121 Caenorhabditis elegans From_analysis: TreeFam
            Inparanoid_8
            Panther
            WormBase-Compara
      WBGene00015329 Caenorhabditis elegans From_analysis: Panther
            WormBase-Compara
    Structured_description: Concise_description: aly-3 encodes an RRM motif-containing protein orthologous to human THOC4 (OMIM:604171), and paralogous to ALY-1 and ALY-2; by orthology, ALY-3 is thought to promote recruitment of mRNA export factor to mRNAs; however, ALY-3 has no grossly obvious function in four-way RNAi assays of ALY-1/-3 and W04D2.6, and aly-3(RNAi) had no obvious effect on nuclear retention of tra-2 mRNA in the absence of TRA-1. Paper_evidence: WBPaper00030790
          Curator_confirmed: WBPerson567
          Date_last_updated: 09 Dec 2007 00:00:00
      Automated_description: Predicted to enable mRNA binding activity. Predicted to be involved in mRNA export from nucleus. Predicted to be located in nucleus. Is an ortholog of human ALYREF (Aly/REF export factor). Paper_evidence: WBPaper00065943
          Curator_confirmed: WBPerson324
            WBPerson37462
          Inferred_automatically: This description was generated automatically by a script based on data from the WS291 version of WormBase
          Date_last_updated: 29 Nov 2023 00:00:00
  Molecular_info: Corresponding_CDS: M18.7a
    Corresponding_transcript: M18.7b
      M18.7a.1
    Other_sequence (31)
    Associated_feature (12)
  Experimental_info: RNAi_result (14)
    Expr_pattern: Expr13880
      Expr1015108
      Expr1030068
      Expr1154717
      Expr2009318
      Expr2027554
    Drives_construct: WBCnstr00037716
    Construct_product: WBCnstr00037716
      WBCnstr00040228
    Microarray_results: SMD_M18.7
      193709_at
      A_12_P147690
      Aff_M18.7
      GPL13394_WBGene00000122
      GPL13914_M18.7
      GPL14144_M18.7a_149-208_0.918_6_C
      GPL14144_M18.7a_228-287_0.928_4_B
      GPL14144_M18.7a_663-722_0.947_1_A
      GPL19516_CGZ0011778
      GPL19516_CGZ0030224
      GPL19516_CGZ0030225
      GPL19516_CGZ0030226
      GPL21109_Cat_M18.7a.1
      GPL21109_M18.7a.1
      GPL3518_CE06198
      GPL8304_CE_WBGene00000122_A
      GPL8304_CE_WBGene00000122_B
      GPL8304_CE_WBGene00000122_C
      GPL8673_M18_7aP00206
      GPL8673_M18_7aP00549
      GPL8673_M18_7aP00556
      GPL9450_M18.7
      cea2.c.30515
    Expression_cluster (130)
    Interaction (34)
  Map_info: Map: IV Position: 5.72967 Error: 0.002435
    Positive: Positive_clone: M18 Inferred_automatically: From CDS info
            From sequence, transcript, pseudogene data
    Mapping_data: Multi_point: 5514
        5519
        5280
    Pseudo_map_position
  Reference: WBPaper00013477
    WBPaper00029295
    WBPaper00038491
    WBPaper00055090
    WBPaper00063792
    WBPaper00064012
  Remark: Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. CGC_data_submission
  Method: Gene