osm-9 encodes a TRPV channel homologous to capsaicin receptors; osm-9 is involved in sensory responses to a subset of chemical stimuli and to ASH neuron-mediated osmotic and mechanical stimuli; OSM-9 is also involved in adaptation to volatile odorants and salts; OSM-9 is expressed in a variety of sensory neurons and shows neuron-specific localization to either the cell body or the cilium.
Enables calcium channel activity and temperature-gated cation channel activity. Involved in several processes, including heat acclimation; negative adaptation of signaling pathway; and nervous system process. Located in neuronal cell body; non-motile cilium; and perinuclear region of cytoplasm. Expressed in RIG; head mesodermal cell; rectal gland cell; sensory neurons; and uterine toroidal epithelial cell. Human ortholog(s) of this gene implicated in several diseases, including keratosis (multiple); motor neuron disease (multiple); and osteochondrodysplasia (multiple). Is an ortholog of human TRPV3 (transient receptor potential cation channel subfamily V member 3); TRPV4 (transient receptor potential cation channel subfamily V member 4); and TRPV5 (transient receptor potential cation channel subfamily V member 5).