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WormBase Tree Display for Gene: WBGene00001758

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Name Class

WBGene00001758EvidencePerson_evidenceWBPerson1846
SMapS_parentSequenceY45G12C
IdentityVersion1
NameCGC_namegst-10
Sequence_nameY45G12C.2
Molecular_nameY45G12C.2a
Y45G12C.2a.1
CE21937
Y45G12C.2b
CE51120
Y45G12C.2b.1
Other_nameCELE_Y45G12C.2Accession_evidenceNDBBX284605
Public_namegst-10
DB_infoDatabase (12)
SpeciesCaenorhabditis elegans
HistoryVersion_change107 Apr 2004 11:29:25WBPerson1971EventImportedInitial conversion from geneace
StatusLive
Gene_infoBiotypeSO:0001217
Gene_classgst
AlleleWBVar00204504
WBVar00296338
WBVar01499528
WBVar01499167
WBVar01490528
WBVar01490529
WBVar01499740
WBVar02090477
WBVar00249389
WBVar00992888
WBVar00992889
WBVar00452096
WBVar00452097
WBVar02076455
WBVar00992890
WBVar00992891
WBVar00452098
WBVar00992892
WBVar00992893
WBVar00992894
WBVar00992895
WBVar00582327
WBVar00582328
WBVar02031880
WBVar00261817
WBVar00252429
WBVar01499676
WBVar01498943
WBVar01498944
WBVar01499496
WBVar01499316
WBVar01612553
WBVar01500066
RNASeq_FPKM (74)
GO_annotation00094967
00094968
00094969
00094970
00094971
00094972
00094973
00094974
00094975
00094976
00094977
00094978
00094979
00094980
00094981
Ortholog (66)
Paralog (45)
Structured_descriptionConcise_descriptiongst-10 encodes a glutathione S-transferase with similarity to the pi class of human glutathione S-transferases; GST-10 catalyzes the conjugation of glutathione to 4-hydroxynonenal in vitro.Paper_evidenceWBPaper00004663
Curator_confirmedWBPerson48
WBPerson1843
Date_last_updated11 Jan 2012 00:00:00
Automated_descriptionEnables glutathione transferase activity. Involved in several processes, including determination of adult lifespan; heat acclimation; and response to UV-C. Predicted to be located in cytosol. Expressed in head and tail. Used to study obesity. Human ortholog(s) of this gene implicated in several diseases, including Alzheimer's disease; autoimmune disease (multiple); carcinoma (multiple); and hematologic cancer (multiple). Is an ortholog of human GSTP1 (glutathione S-transferase pi 1).Paper_evidenceWBPaper00065943
Curator_confirmedWBPerson324
WBPerson37462
Inferred_automaticallyThis description was generated automatically by a script based on data from the WS291 version of WormBase
Date_last_updated29 Nov 2023 00:00:00
Disease_infoExperimental_modelDOID:9970Homo sapiensPaper_evidenceWBPaper00035962
Curator_confirmedWBPerson38202
Date_last_updated29 Jun 2018 00:00:00
Potential_model (139)
Models_disease_in_annotationWBDOannot00000566
Molecular_infoCorresponding_CDSY45G12C.2a
Y45G12C.2b
Corresponding_transcriptY45G12C.2a.1
Y45G12C.2b.1
Other_sequence (11)
Associated_featureWBsf231517
WBsf231518
Experimental_infoRNAi_result (21)
Expr_patternChronogram415
Expr3779
Expr6981
Expr1017258
Expr1031047
Expr1160093
Expr2012293
Expr2030529
Drives_constructWBCnstr00002820
WBCnstr00011654
WBCnstr00036711
Construct_productWBCnstr00011654
WBCnstr00036711
AntibodyWBAntibody00000875
Microarray_results (19)
Expression_cluster (346)
Interaction (46)
Map_infoMapVPosition-14.8306Error0.069584
PositivePositive_cloneY45G12CInferred_automaticallyFrom CDS info
From sequence, transcript, pseudogene data
Mapping_dataMulti_point4922
5418
Pseudo_map_position
Reference (26)
RemarkSequence connection from [Engle MR, Zimniak P]
Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC.CGC_data_submission
MethodGene