WormBase Tree Display for Gene: WBGene00010290

WBGene00010290 SMap: S_parent: Sequence: CHROMOSOME_V
  Identity: Version: 2
    Name: Sequence_name: F58H1.7
      Molecular_name: F58H1.7a
        F58H1.7a.1
        CE20895
        F58H1.7b
        CE11412
        F58H1.7b.1
      Other_name: nrap-1 Paper_evidence: WBPaper00053454
          Remark: This name was not requested prior to publication. It is felt that this would introduce confusion as there is a human gene NRAP which is not the ortholog of this gene. This gene also appears to be restricted to invertebrates as there is only a single fly ortholog according to AGR/DIOPT.
        CELE_F58H1.7 Accession_evidence: NDB BX284605
      Public_name: F58H1.7
    DB_info: Database: AceView gene 5M444
        WormQTL gene WBGene00010290
        WormFlux gene WBGene00010290
        NDB locus_tag CELE_F58H1.7
        Panther gene CAEEL|WormBase=WBGene00010290|UniProtKB=G5EBT2
          family PTHR20967
        NCBI gene 179636
        RefSeq protein NM_001047675.4
            NM_001047674.3
        TrEMBL UniProtAcc G5EEF9
            G5EBT2
        UniProt_GCRP UniProtAcc G5EBT2
    Species: Caenorhabditis elegans
    History: Version_change: 1 26 May 2004 16:54:51 WBPerson1971 Event: Imported: Initial conversion from CDS class of WS125
        2 02 Jan 2021 22:55:32 WBPerson1983 Name_change: Other_name: nrap-1
    Status: Live
  Gene_info: Biotype: SO:0001217
    Allele: WBVar00094471 Inferred_automatically: From strain object: RB2511
      WBVar01866517
      WBVar01866518
      WBVar02137212
      WBVar01499357
      WBVar01499358
      WBVar01499547
      WBVar01743632
      WBVar00471783
      WBVar00471784
      WBVar00471785
      WBVar00471786
      WBVar00471787
      WBVar00471788
      WBVar02068817
      WBVar01974923
      WBVar00276771
      WBVar01052036
      WBVar01052037
      WBVar01052038
      WBVar01052039
      WBVar01052040
      WBVar01052041
      WBVar01052042
      WBVar01052043
      WBVar01052044
      WBVar01052045
      WBVar01052046
      WBVar01052047
      WBVar01052048
      WBVar01484752
      WBVar01990989
      WBVar01500212
      WBVar01500213
      WBVar01499299
      WBVar01499316
      WBVar00006075
      WBVar01590196
    Strain: WBStrain00033186
    RNASeq_FPKM (74)
    Ortholog: WBGene00041712 Caenorhabditis briggsae From_analysis: OrthoMCL
            OMA
            Inparanoid_8
            WormBase-Compara
      WBGene00052395 Caenorhabditis remanei From_analysis: OMA
            Inparanoid_8
            WormBase-Compara
      WBGene00140569 Caenorhabditis brenneri From_analysis: OMA
            Inparanoid_8
            WormBase-Compara
      WBGene00118329 Pristionchus pacificus From_analysis: OMA
            Inparanoid_8
            WormBase-Compara
      WBGene00120950 Caenorhabditis japonica From_analysis: Inparanoid_8
            WormBase-Compara
      WBGene00193459 Caenorhabditis brenneri From_analysis: WormBase-Compara
      CBOVI.g2081 Caenorhabditis bovis From_analysis: WormBase-Compara
      CSP21.g14245 Caenorhabditis parvicauda From_analysis: WormBase-Compara
      CSP26.g10648 Caenorhabditis zanzibari From_analysis: WormBase-Compara
      CSP28.g12025 Caenorhabditis panamensis From_analysis: WormBase-Compara
      CSP29.g833 Caenorhabditis becei From_analysis: WormBase-Compara
      CSP31.g7068 Caenorhabditis uteleia From_analysis: WormBase-Compara
      CSP32.g4341 Caenorhabditis sulstoni From_analysis: WormBase-Compara
      CSP38.g14874 Caenorhabditis quiockensis From_analysis: WormBase-Compara
      CSP39.g6594 Caenorhabditis waitukubuli From_analysis: WormBase-Compara
      CSP40.g14373 Caenorhabditis tribulationis From_analysis: WormBase-Compara
      Cang_2012_03_13_00935.g15011 Caenorhabditis angaria From_analysis: WormBase-Compara
      Cni-F58H1.7 Caenorhabditis nigoni From_analysis: WormBase-Compara
      Csp11.Scaffold629.g7758 Caenorhabditis tropicalis From_analysis: WormBase-Compara
      Csp5_scaffold_00230.g7556 Caenorhabditis sinica From_analysis: WormBase-Compara
      FL83_10714 Caenorhabditis latens From_analysis: WormBase-Compara
      GCK72_018149 Caenorhabditis remanei From_analysis: WormBase-Compara
      OTIPU.nOt.2.0.1.g00648 Oscheius tipulae From_analysis: WormBase-Compara
      Pan_g16716 Panagrellus redivivus From_analysis: WormBase-Compara
      Sp34_50143100 Caenorhabditis inopinata From_analysis: WormBase-Compara
      chrV_pilon.g15891 Caenorhabditis elegans From_analysis: WormBase-Compara
      WBGene00265210 Strongyloides ratti From_analysis: WormBase-Compara
      FB:FBgn0051221 Drosophila melanogaster From_analysis: EnsEMBL-Compara
            Hieranoid
            Inparanoid
            OrthoFinder
            OrthoInspector
            Panther
            PhylomeDB
            SonicParanoid
    Structured_description: Automated_description: Expressed in glutamatergic neurons. Is predicted to encode a protein with the following domains: LDL receptor-like superfamily; Low-density lipoprotein (LDL) receptor class A repeat; and Low-density lipoprotein receptor domain class A. Paper_evidence: WBPaper00065943
          Curator_confirmed: WBPerson324
            WBPerson37462
          Inferred_automatically: This description was generated automatically by a script based on data from the WS291 version of WormBase
          Date_last_updated: 29 Nov 2023 00:00:00
  Molecular_info: Corresponding_CDS: F58H1.7a
      F58H1.7b
    Corresponding_transcript: F58H1.7a.1
      F58H1.7b.1
    Other_sequence (47)
    Associated_feature (12)
  Experimental_info: RNAi_result: WBRNAi00002177 Inferred_automatically: RNAi_primary
      WBRNAi00049072 Inferred_automatically: RNAi_primary
      WBRNAi00111163 Inferred_automatically: RNAi_primary
      WBRNAi00016027 Inferred_automatically: RNAi_primary
      WBRNAi00033529 Inferred_automatically: RNAi_primary
    Expr_pattern: Expr13695
      Expr1017647
      Expr1034490
      Expr1152812
      Expr2004426
      Expr2022649
    Drives_construct: WBCnstr00031523
      WBCnstr00039944
    Construct_product: WBCnstr00031523
      WBCnstr00039944
    Microarray_results (27)
    Expression_cluster: WBPaper00031040:Cluster_3
      WBPaper00031040:TGF-beta_adult_upregulated
      WBPaper00032425:down_in_rde-4
      WBPaper00032528:L3_enriched
      WBPaper00033065:cyc-1(RNAi)_downregulated
      WBPaper00035269:cde-1_regulated
      WBPaper00037682:sma-2_sma-4_upregulated
      WBPaper00037950:A-class-motor-neurons_L2-larva_expressed
      WBPaper00037950:BAG-neuron_blastula-embryo_expressed
      WBPaper00037950:BAG-neuron_embryo_enriched
      WBPaper00037950:bodywall-muscle_L2-larva_expressed
      WBPaper00037950:CEP-sheath-cells_Day1-adult_expressed
      WBPaper00037950:dopaminergic-neurons_L1-larva_expressed
      WBPaper00037950:dopaminergic-neurons_L3-L4-larva_expressed
      WBPaper00037950:dopaminergic-neurons_larva_enriched
      WBPaper00037950:GABAergic-motor-neurons_L2-larva_expressed
      WBPaper00037950:glr-1(+)-neurons_larva_enriched
      WBPaper00037950:hypodermis_L3-L4-larva_expressed
      WBPaper00037950:PVD-OLL-neurons_L3-L4-larva_expressed
      WBPaper00037950:PVD-OLL-neurons_larva_enriched
      WBPaper00038438:P.lumniescens_24hr_upregulated_TilingArray
      WBPaper00042215:wdr-23(tm1817)_upregulated
      WBPaper00044037:eat-2_upregulated
      WBPaper00044736:flat_dev_expression
      WBPaper00044743:wdr-23_neuron_upregulated
      WBPaper00045314:S.aureus-induced_N2
      WBPaper00045571:germline-ablation_upregulated
      WBPaper00045861:wdr-5(ok1417)_upregulated
      WBPaper00046012:tdp-1(ok803)_upregulated
      WBPaper00046497:B.thuringiensis_0.1mix_upregulated_12h
      WBPaper00046497:B.thuringiensis_0.5mix_upregulated_12h
      WBPaper00047131:daf-2(e1370)_upregulated_hel-1(gk148684)-background
      WBPaper00047131:daf-2(e1370)_upregulated_N2-background
      WBPaper00048988:neuron_enriched
      WBPaper00048988:neuron_expressed
      WBPaper00049920:Glucose-Diet_upregulated_hyl-2(tm2031)
      WBPaper00049920:Glucose-Diet_upregulated_N2
      WBPaper00050053:muscle_enriched_Day4
      WBPaper00050234:lin-28(RNAi)_downregulated
      WBPaper00050344:AFD-neuron_enriched
      WBPaper00050344:PLM-neuron_enriched
      WBPaper00050488:20C_vs_25C_regulated_N2_adult
      WBPaper00050488:adult_vs_dauer_regulated_N2_20C
      WBPaper00050488:mir-34(gk437)_vs_mir-34(OverExpression)_regulated_adult_20C
      WBPaper00050488:mir-34(gk437)_vs_mir-34(OverExpression)_regulated_adult_25C
      WBPaper00050488:mir-34(OverExpression)_vs_N2_regulated_adult_20C
      WBPaper00050726:OsmoticStress_regulated_NoFood
      WBPaper00050726:starvation_regulated_LowSalt
      WBPaper00050743:elli-1(sam-3)_downregulated
      WBPaper00050859:upregulated_P-granule(-)GFP(+)_vs_control_day2-adult
      WBPaper00050859:upregulated_P-granule(-)GFP(-)_vs_control_day2-adult
      WBPaper00050859:upregulated_pgl-1(ct131)_vs_control_day1-adult
      WBPaper00050990:arcade_intestinal-valve_expressed
      WBPaper00050990:body-muscle_expressed
      WBPaper00050990:GABAergic-neuron_expressed
      WBPaper00050990:hypodermis_expressed
      WBPaper00050990:intestine_expressed
      WBPaper00050990:NMDA-neuron_expressed
      WBPaper00050990:pharynx_expressed
      WBPaper00051558:aging_regulated
      WBPaper00052884:emb-4(hc60)_upregulated
      WBPaper00053184:sma-2(rax5)_upregulated
      WBPaper00053184:sma-4(rax3)_upregulated
      WBPaper00053302:zidovudine_24h_regulated
      WBPaper00053388:dauer_regulated_Cluster2
      WBPaper00053599:female_vs_male_downregulated
      WBPaper00053810:isp-1(qm150)_upregulated
      WBPaper00053810:nuo-6(qm200)_upregulated
      WBPaper00054758:alg-1(gk204)_upregulated
      WBPaper00055060:flr-1(RNAi)_upregulated
      WBPaper00055354:Metformin_upregulated
      WBPaper00055354:Rifampicin-Allantoin_upregulated
      WBPaper00055482:pmt-2(RNAi)_upregulated
      WBPaper00055648:male-tail_expressed
      WBPaper00055648:nerve-ring_expressed
      WBPaper00055941:nuo-6(qm200);atfs-1(gk3094)_upregulated
      WBPaper00055971:nhl-2(ok818)_25C_downregulated
      WBPaper00056090:E.faecalis_upregulated_hpx-2(dg047)
      WBPaper00056090:E.faecalis_upregulated_N2
      WBPaper00056161:male_enriched_siRNA
      WBPaper00056443:sek-1(km4)_upregulated
      WBPaper00056471:aak-1(tm1944);aak-2(ok524)_upregulated
      WBPaper00056471:S.aureus-4h_upregulated_N2
      WBPaper00056997:nmad-1(ok3133)_upregulated_germline_25C
      WBPaper00058598:sin-3(tm1276)_downregulated
      WBPaper00058711:paraquat_downregulated
      WBPaper00058711:skn-1(lax188)_upregulated
      WBPaper00058948:PA14_downregulated
      WBPaper00059027:neuron-synapses_depleted
      WBPaper00059566:wdr-23(mac32)_upregulated
      WBPaper00059609:malt-1_ilc-17.1_nfki-1_downregulated
      WBPaper00059664:srbc-48(ac23)_upregulated
      WBPaper00059728:20ug_cholesterol_upregulated
      WBPaper00059754:C.neoformans_H99_upregulated
      WBPaper00059754:E.faecalis_OG1RF_upregulated
      WBPaper00059763:neuron_acr-2(n2420gf)_regulated
      WBPaper00059763:neuron_expressed
      WBPaper00060273:isp-1(qm150)_upregulated
      WBPaper00060358:B.thuringiensis_non-pathogen_regulated_elt-2(RNAi)
      WBPaper00060358:B.thuringiensis_pathogen_regulated_elt-2(RNAi)
      WBPaper00060399:pqm-1(ok485)_upregulated_CoCl2_6hr
      WBPaper00060459:bcat-1(RNAi)_upregulated
      WBPaper00060661:sensory-neuron_enriched
      WBPaper00060811:L1_vs_adult_upregulated_neural
      WBPaper00060909:atfs-1(cmh15)_downregulated
      WBPaper00061007:HB101_upregulated
      WBPaper00061007:S.aquatilis_upregulated
      WBPaper00061007:X.citri_upregulated
      WBPaper00061081:E.faecalis_upregulated_N2
      WBPaper00061081:E.faecalis_upregulated_skpo-1(ok1640)
      WBPaper00061203:sin-3(tm1276)_upregulated
      WBPaper00061203:spr-1(ok2144)_upregulated
      WBPaper00061274:microgravity_downregulated
      WBPaper00061340:ADA_ADE_grandparent
      WBPaper00061340:ADL
      WBPaper00061340:ASH
      WBPaper00061340:AUA
      WBPaper00061340:Body_wall_muscle
      WBPaper00061340:DVC
      WBPaper00061340:Excretory_cell_parent
      WBPaper00061340:Excretory_gland
      WBPaper00061340:I2_grandparent
      WBPaper00061340:Neuroblast_ADE_ADA
      WBPaper00061340:NSM_parent
      WBPaper00061340:Parents_of_Y_DA6_DA7_DA9
      WBPaper00061340:Parent_of_exc_duct_pore_DB_1_3
      WBPaper00061340:Parent_of_exc_gland_AVK
      WBPaper00061341:28C_24h_upregulated
      WBPaper00061341:28C_48h_upregulated
      WBPaper00061439:unc-30(ok613)_upregulated
      WBPaper00061439:unc-30(ok613)_upregulated_P.aeruginosa-infection
      WBPaper00061527:ccg-1_12351-ZC410.5
      WBPaper00061651:AIB_enriched
      WBPaper00061651:AIZ_enriched
      WBPaper00061651:AQR_enriched
      WBPaper00061651:AUA_enriched
      WBPaper00061651:AVM_enriched
      WBPaper00061651:DVC_enriched
      WBPaper00061651:LUA_enriched
      WBPaper00061651:PHC_enriched
      WBPaper00061651:PQR_enriched
      WBPaper00061651:PVM_enriched
      WBPaper00061651:PVQ_enriched
      WBPaper00061651:PVR_enriched
      WBPaper00061651:PVW_enriched
      WBPaper00061651:RIG_enriched
      WBPaper00061753:csr-1(tor159)_upregulated_25C
      WBPaper00061902:camt-1(ok515)_regulated_RMG
      WBPaper00061995:mter-4(syb3662syb3403)_downregulated
      WBPaper00062095:unc-4(e120)_upregulated_VA-neuron
      WBPaper00062103:neuron_enriched
      WBPaper00062159:hda-2(ok1479)_upregulated
      WBPaper00062193:skn-1(RNAi)_upregulated
      WBPaper00062325:muscle_depleted_coding-RNA
      WBPaper00064005:starvation_upregulated_aptf-1(gk794)_mRNA
      WBPaper00064088:Day-1-adult_vs_L4_downregulated_fem-3(q20)
      WBPaper00064088:Day-3-adult_vs_L4_downregulated_fem-3(q20)
      WBPaper00064156:lipl-4(overexpress)_upregulated
      WBPaper00064306:Agaro-oligosaccharides_upregulated
      WBPaper00064716:paraquat_downregulated
      WBPaper00064871:hypoxia_downregulated_F1
      WBPaper00064933:bcf-1(ylf1)_downregulated_transcript
      WBPaper00065096:25C_vs_20C_downregulated
      WBPaper00065158:AFD_enriched
      WBPaper00065623:82
      WBPaper00065623:116
      WBPaper00065623:149
      WBPaper00065623:154
      WBPaper00065623:156
      WBPaper00065623:166
      WBPaper00065749:Heat-Shock_downregulated_endu-2(tm4977)
      WBPaper00065835:Day11_vs_Day1_upregulated
      WBPaper00065841:20_1
      WBPaper00065841:39_2
      WBPaper00065841:39_3
      WBPaper00065841:54_0
      WBPaper00065841:62_0
      WBPaper00065841:70_0
      WBPaper00065841:70_1
      WBPaper00065841:75_0
      WBPaper00065841:87_0
      WBPaper00065841:90_0
      WBPaper00065841:97_0
      WBPaper00065841:107_0
      WBPaper00065841:108_0
      WBPaper00065841:114_0
      WBPaper00065841:119_0
      WBPaper00065841:120_0
      WBPaper00065841:122_0
      WBPaper00065841:137_0
      WBPaper00065841:140_0
      WBPaper00065975:P-body_vs_WholeAnimal_depleted
      WBPaper00065993:glp-1(e2141)_upregulated
      WBPaper00066146:germline-inx-14(RNAi)_upregulated_PA14
      cgc4386_cluster_1_6
      WBPaper00025141:N2_Expressed_Genes
      WBPaper00025141:unc-4::GFP_Expressed_Genes
      WBPaper00027342:alpha-Synuclein(A53T)_downregulated
      WBPaper00029437:dcr-1_upregulated
      WBPaper00030839:Embryo_Pan_Neuronal
      WBPaper00030839:Larval_Pan_Neuronal
      WBPaper00031003:0hr_muscle_depleted
      WBPaper00031003:total_muscle_depleted
      WBPaper00031252:AIN-1_IP_enriched
      WBPaper00031532:Larva_Pan_Neuronal_Enriched
      WBPaper00032948:StarveUp3
      WBPaper00034661:AgNPs_downregulated
      WBPaper00035084:L2_enriched_AIN-2_IP
      WBPaper00035084:L3_enriched_AIN-2_IP
      WBPaper00035084:L4_enriched_AIN-2_IP
      WBPaper00035227:heat_shock_regulated
      WBPaper00035588:alg-1(-)_upregulated
      WBPaper00035873:dpy-9_regulated
      WBPaper00035873:dpy-10_regulated
      WBPaper00035873:osm-8_regulated
      WBPaper00035873:osm-11_regulated
      WBPaper00036286:Pattern_G
      WBPaper00038060:SUMO-1_downregulated
      WBPaper00038172:tax-6null_up_regulated
      WBPaper00038304:octr-1_regulated
      WBPaper00039851:Live_C_albicans_vs_HK_OP50
      WBPaper00040603:tdp-1(lf)_down_vs_N2_FC_1.2
      WBPaper00040821:Au-NP_regulated
      WBPaper00041002:HF_3d_2.0mM_Up
      WBPaper00041002:HQ_3d_2.0mM_Up
      WBPaper00041939:control_vs_EtBr-exposed_48h
      WBPaper00041939:control_vs_UVC-EtBr-exposed_48h
      WBPaper00041939:control_vs_UVC-EtBr-exposed_51h
      WBPaper00041939:EtBr-exposed_vs_UVC-exposed_48h
      WBPaper00041939:UVC-EtBr-exposed_vs_UVC-exposed_48h
      WBPaper00041939:UVC-EtBr-exposed_vs_UVC-exposed_51h
      WBPaper00041960:N2_fasting_upregulated_anytime
      WBPaper00042258:DA1877_upregulated_GravidAdult
      WBPaper00042274:tbx-2(bx59)_upregulated
      WBPaper00045673:colistin_upregulated
      WBPaper00047070:N2_starvation_upregulated
      WBPaper00048989:eat-2(ad465)_rapamycin_downregulated
      WBPaper00050538:Fasting_upregulated
      WBPaper00050538:Fasting_upregulated_cholesterol-dependent
      WBPaper00053236:Starvation_regulated_GR1307
      WBPaper00053236:Starvation_regulated_N2
      WBPaper00056330:mrps-5(RNAi)_upregulated
      WBPaper00057098:SiO2-nanoparticles_upregulated
      [cgc6390]:Cluster_A
    Interaction (91)
  Map_info: Positive: Positive_clone: F58H1 Inferred_automatically: From sequence, transcript, pseudogene data
    Interpolated_map_position: V 3.5457
  Reference: WBPaper00053454
    WBPaper00060161
    WBPaper00064302
  Method: Gene