WormBase Tree Display for Variation: WBVar02146270

WBVar02146270 Name: Public_name: tm8294
    Other_name: CE52179:p.Asn240MetfsTer16
      ZK973.6c.1:c.719_776delinsTGTCATCAGCATGCGTGATGTCA
      ZK973.6a.1:c.740_797delinsTGTCATCAGCATGCGTGATGTCA
      CE33588:p.Asn247MetfsTer16
    HGVSg: CHROMOSOME_I:g.4325044_4325101delinsTGTCATCAGCATGCGTGATGTCA
  Sequence_details: SMap: S_parent: Sequence: ZK973
    Flanking_sequences: gggatctcgttggcggacgacgtgtcgaga tccagatgtcatcagcatgcgtgaagtgac
    Mapping_target: ZK973
    Source_location: 7 CHROMOSOME_I 4325043 4325102 Inferred_automatically: National_Bioresource_Project
    Type_of_mutation: Insertion: TGTCATCAGCATGCGTGATGTCA
      Deletion
    PCR_product: tm8294_external
      tm8294_internal
    SeqStatus: Sequenced
  Variation_type: Allele
  Origin: Species: Caenorhabditis elegans
    Laboratory: FX
    Author: Mitani S
    DB_info: Database: National_Bioresource_Project seq 8294
    NBP_allele
    Status: Live
  Affects: Gene: WBGene00000140
    Transcript: ZK973.6c.1 VEP_consequence: frameshift_variant
        VEP_impact: HIGH
        HGVSc: ZK973.6c.1:c.719_776delinsTGTCATCAGCATGCGTGATGTCA
        HGVSp: CE52179:p.Asn240MetfsTer16
        cDNA_position: 719-776
        CDS_position: 719-776
        Protein_position: 240-259
        Exon_number: 5/30
        Codon_change: aATATGGATAAACAATGGAGAGATGGAATTCTATTCTGTGCTCTTGTATCTCGATGGCGt/aTGTCATCAGCATGCGTGATGTCAt
        Amino_acid_change: NMDKQWRDGILFCALVSRWR/MSSACVMSX
      ZK973.6a.1 VEP_consequence: frameshift_variant
        VEP_impact: HIGH
        HGVSc: ZK973.6a.1:c.740_797delinsTGTCATCAGCATGCGTGATGTCA
        HGVSp: CE33588:p.Asn247MetfsTer16
        cDNA_position: 740-797
        CDS_position: 740-797
        Protein_position: 247-266
        Exon_number: 5/31
        Codon_change: aATATGGATAAACAATGGAGAGATGGAATTCTATTCTGTGCTCTTGTATCTCGATGGCGt/aTGTCATCAGCATGCGTGATGTCAt
        Amino_acid_change: NMDKQWRDGILFCALVSRWR/MSSACVMSX
  Isolation: Mutagen: TMP/UV
  Genetics: Map: I
  Description: Phenotype_not_observed: WBPhenotype:0000062 Person_evidence: WBPerson7743
        Curator_confirmed: WBPerson712
        Remark: Classified as homozygous viable by the National BioResource Project of Japan. Person_evidence: WBPerson7743
            Curator_confirmed: WBPerson712
  Remark: 4443/4444-TGTCATCAGCATGCGTGATGTCA-4501/4502 (58 bp deletion + 23 bp insertion)
    This knockout was generated by the National Bioresource Project, Tokyo, Japan, which is part of the International C. elegans Gene Knockout Consortium, which should be acknowledged in any publications resulting from its use. Paper_evidence: WBPaper00041807
  Method: NBP_knockout_allele