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WormBase Tree Display for Variation: WBVar00600761

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Name Class

WBVar00600761EvidencePaper_evidenceWBPaper00027764
NamePublic_nametu142
Sequence_detailsMapping_targetPPA01382
Type_of_mutationSubstitutionga
SeqStatusPending_curation
Variation_typeAllele
OriginSpeciesPristionchus pacificus
LaboratoryTU
StatusLive
AffectsGeneWBGene00195123
DescriptionPhenotypeWBPhenotype:0000220Paper_evidenceWBPaper00027764
Curator_confirmedWBPerson712
RemarkThis mutation inhibits the programmed cell death of P3.p and P4.p without affecting apoptosis of P(1,2,9-11).p. Surviving cells differentiate into ectopic vulval tissue.Paper_evidenceWBPaper00027764
Curator_confirmedWBPerson712
WBPhenotype:0002027Paper_evidenceWBPaper00027764
Curator_confirmedWBPerson712
RemarkDetailed cell-lineage analysis showed that mutant worms have lineage defects, i.e., lineage reversals, restricted to the P7.p lineage. Gonad independent differentiation (Gid) was measured after gonad ablation.Paper_evidenceWBPaper00027764
Curator_confirmedWBPerson712
PenetranceCompletePaper_evidenceWBPaper00027764
Curator_confirmedWBPerson712
ReferenceWBPaper00027764
Remarktu142 is a Gly248Arg mutationPaper_evidenceWBPaper00027764
MethodSubstitution_allele