WormBase Tree Display for Variation: WBVar00275498
expand all nodes | collapse all nodes | view schema
| WBVar00275498 | Name | Public_name | zu154 | ||||||
|---|---|---|---|---|---|---|---|---|---|
| Sequence_details | SeqStatus | Pending_curation | |||||||
| Variation_type | Allele | ||||||||
| Origin | Species | Caenorhabditis elegans | |||||||
| Strain | WBStrain00007250 | ||||||||
| WBStrain00022474 | |||||||||
| Laboratory | JJ | ||||||||
| Status | Live | ||||||||
| Affects | Gene | WBGene00004027 | |||||||
| Interactor | WBInteraction000501692 | ||||||||
| WBInteraction000520747 | |||||||||
| Description | Phenotype | WBPhenotype:0000050 | Paper_evidence | WBPaper00001584 | |||||
| Curator_confirmed | WBPerson2021 | ||||||||
| Recessive | Paper_evidence | WBPaper00001584 | |||||||
| Curator_confirmed | WBPerson2021 | ||||||||
| Variation_effect | Probable_null_via_phenotype | Paper_evidence | WBPaper00001584 | ||||||
| Curator_confirmed | WBPerson2021 | ||||||||
| EQ_annotations | Life_stage | WBls:0000003 | PATO:0000460 | Paper_evidence | WBPaper00001584 | ||||
| Curator_confirmed | WBPerson2021 | ||||||||
| Maternal | |||||||||
| WBPhenotype:0000052 | Person_evidence | WBPerson261 | |||||||
| Curator_confirmed | WBPerson712 | ||||||||
| Remark | Maternal effect lethal, often with two distinct pharynges; additional pharynx and intestinal tissue from P2 (transformed to EMS fate). | Person_evidence | WBPerson261 | ||||||
| Curator_confirmed | WBPerson712 | ||||||||
| WBPhenotype:0000414 | Person_evidence | WBPerson261 | |||||||
| Curator_confirmed | WBPerson712 | ||||||||
| Remark | Additional pharynx intestinal tissue from P2 (transformed to EMS fate). | Person_evidence | WBPerson261 | ||||||
| Curator_confirmed | WBPerson712 | ||||||||
| WBPhenotype:0001276 | Paper_evidence | WBPaper00003331 | |||||||
| Curator_confirmed | WBPerson2987 | ||||||||
| Remark | pie-1(zu154) resulted in ectopic expression of the ges-1(delta B)::lacZ transgene (in ectopic anterior intestine) in embryos in which the EMS blastomere underwent laser ablation (Table 1, Figure 6). | Paper_evidence | WBPaper00003331 | ||||||
| Curator_confirmed | WBPerson2987 | ||||||||
| Phenotype_assay | Genotype | ges-1(delta B)::lacZ | Paper_evidence | WBPaper00003331 | |||||
| Curator_confirmed | WBPerson2987 | ||||||||
| WBPhenotype:0001635 | Paper_evidence | WBPaper00001584 | |||||||
| Person_evidence | WBPerson261 | ||||||||
| Curator_confirmed | WBPerson2021 | ||||||||
| WBPerson712 | |||||||||
| Remark | Mutants have large clusters of excess pharyngeal cells. These clusters are surrounded by a basement membrane and some of them contain grinder-like structures | Paper_evidence | WBPaper00001584 | ||||||
| Curator_confirmed | WBPerson2021 | ||||||||
| Often with two distinct pharynges; additional pharynx tissue from P2 (transformed to EMS fate). | Person_evidence | WBPerson261 | |||||||
| Curator_confirmed | WBPerson712 | ||||||||
| Recessive | Paper_evidence | WBPaper00001584 | |||||||
| Curator_confirmed | WBPerson2021 | ||||||||
| Variation_effect | Probable_null_via_phenotype | Paper_evidence | WBPaper00001584 | ||||||
| Curator_confirmed | WBPerson2021 | ||||||||
| EQ_annotations | Life_stage | WBls:0000003 | PATO:0000460 | Paper_evidence | WBPaper00001584 | ||||
| Curator_confirmed | WBPerson2021 | ||||||||
| Maternal | |||||||||
| WBPhenotype:0001636 | Paper_evidence | WBPaper00001584 | |||||||
| Person_evidence | WBPerson261 | ||||||||
| Curator_confirmed | WBPerson2021 | ||||||||
| WBPerson712 | |||||||||
| Remark | pie-l mutant embryos appear to produce too many intestinal cells | Paper_evidence | WBPaper00001584 | ||||||
| Curator_confirmed | WBPerson2021 | ||||||||
| Additional intestinal tissue from P2 (transformed to EMS fate). | Person_evidence | WBPerson261 | |||||||
| Curator_confirmed | WBPerson712 | ||||||||
| Recessive | Paper_evidence | WBPaper00001584 | |||||||
| Curator_confirmed | WBPerson2021 | ||||||||
| Variation_effect | Probable_null_via_phenotype | Paper_evidence | WBPaper00001584 | ||||||
| Curator_confirmed | WBPerson2021 | ||||||||
| EQ_annotations | Life_stage | WBls:0000003 | PATO:0000460 | Paper_evidence | WBPaper00001584 | ||||
| Curator_confirmed | WBPerson2021 | ||||||||
| Maternal | |||||||||
| Phenotype_assay | Temperature | 16C, 25C | Paper_evidence | WBPaper00001584 | |||||
| Curator_confirmed | WBPerson2021 | ||||||||
| WBPhenotype:0002078 | Paper_evidence | WBPaper00038409 | |||||||
| Curator_confirmed | WBPerson712 | ||||||||
| Remark | An effect on the deposition of H3K4me3 at two- and four-cell stages was not observed; however, at the eight-cell stage, embryos depleted of PIE-1 acquire the H3K4me3 mark in P3 and in the somatic cells in which H3K4me3 is normally poor. Deposition of H3K4me3 in P4 was also observed. | Paper_evidence | WBPaper00038409 | ||||||
| Curator_confirmed | WBPerson712 | ||||||||
| Phenotype_not_observed | WBPhenotype:0001642 | Paper_evidence | WBPaper00001584 | ||||||
| Curator_confirmed | WBPerson2021 | ||||||||
| Remark | Mutant embryos appear identical to wild-type embryos in terms of size, cleavage rate, and division axes up to the 28-cell stage (data not shown) | Paper_evidence | WBPaper00001584 | ||||||
| Curator_confirmed | WBPerson2021 | ||||||||
| Recessive | Paper_evidence | WBPaper00001584 | |||||||
| Curator_confirmed | WBPerson2021 | ||||||||
| Variation_effect | Probable_null_via_phenotype | Paper_evidence | WBPaper00001584 | ||||||
| Curator_confirmed | WBPerson2021 | ||||||||
| EQ_annotations | Life_stage | WBls:0000003 | PATO:0000460 | Paper_evidence | WBPaper00001584 | ||||
| Curator_confirmed | WBPerson2021 | ||||||||
| Maternal | |||||||||
| Reference | WBPaper00038409 | ||||||||
| WBPaper00001584 | |||||||||
| WBPaper00003331 | |||||||||
| WBPaper00023708 | |||||||||
| WBPaper00015432 | |||||||||
| WBPaper00011225 | |||||||||
| WBPaper00010539 | |||||||||
| Method | Allele |
