WormBase Tree Display for Variation: WBVar00275320
expand all nodes | collapse all nodes | view schema
| WBVar00275320 | Name | Public_name | y93 | ||||||
|---|---|---|---|---|---|---|---|---|---|
| Sequence_details | SeqStatus | Pending_curation | |||||||
| Variation_type | Allele | ||||||||
| Origin | Species | Caenorhabditis elegans | |||||||
| Strain | WBStrain00035166 | ||||||||
| Laboratory | TY | ||||||||
| Status | Live | ||||||||
| Affects | Gene | WBGene00004746 | |||||||
| Interactor | WBInteraction000052078 | ||||||||
| Description | Phenotype | WBPhenotype:0000066 | Paper_evidence | WBPaper00003262 | |||||
| WBPaper00001171 | |||||||||
| Curator_confirmed | WBPerson712 | ||||||||
| Remark | This is a weak allele with little or no XX lethality observed (1,606 live adults/1,658 embryos laid or 97% viability observed). | Paper_evidence | WBPaper00003262 | ||||||
| Curator_confirmed | WBPerson712 | ||||||||
| y93 is a weak allele of sdc-2, with significant levels of XX viability. At the restrictive temperature y93 fails to complement the strong alleles, y76 and y77; however, y93 complements these alleles at 15C and gives intermediate levels of viability. | Paper_evidence | WBPaper00001171 | |||||||
| Curator_confirmed | WBPerson712 | ||||||||
| Penetrance | Low | 3% lethality observed | Paper_evidence | WBPaper00003262 | |||||
| Curator_confirmed | WBPerson712 | ||||||||
| Paper_evidence | WBPaper00001171 | ||||||||
| Curator_confirmed | WBPerson712 | ||||||||
| Temperature_sensitive | Heat_sensitive | 25 | Paper_evidence | WBPaper00001171 | |||||
| Curator_confirmed | WBPerson712 | ||||||||
| Phenotype_assay | Temperature | 15C, 25C | Paper_evidence | WBPaper00001171 | |||||
| Curator_confirmed | WBPerson712 | ||||||||
| Genotype | sdc-2(y76) or sdc-2(y77) | Paper_evidence | WBPaper00001171 | ||||||
| Curator_confirmed | WBPerson712 | ||||||||
| WBPhenotype:0000136 | Paper_evidence | WBPaper00031121 | |||||||
| Curator_confirmed | WBPerson712 | ||||||||
| Remark | Transcript levels were elevated for sex-1 (2.9-fold), ceh-39(5.2-fold), fox-1(2-fold) and xol-1(4.5-fold) above the levels of these transcripts in wild-type XX animals, as assayed by qRT-PCR. | Paper_evidence | WBPaper00031121 | ||||||
| Curator_confirmed | WBPerson712 | ||||||||
| EQ_annotations | Life_stage | WBls:0000003 | PATO:0000460 | Paper_evidence | WBPaper00031121 | ||||
| Curator_confirmed | WBPerson712 | ||||||||
| Phenotype_assay | Treatment | Dosage compensation-defective XX embryos (dead) were harvested from the progeny of a population of sdc-2(y93) larva treated with scd-2(RNAi) feeding for one generation. Transcript levels were normalized to fasn-1, a gene that is not affected by dosage compensation. | Paper_evidence | WBPaper00031121 | |||||
| Curator_confirmed | WBPerson712 | ||||||||
| Reference | WBPaper00031121 | ||||||||
| WBPaper00001171 | |||||||||
| WBPaper00003262 | |||||||||
| Method | Allele |
